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License Agreements - Innovent (Details) - Innovent - USD ($)
$ in Millions
1 Months Ended 12 Months Ended
Jan. 31, 2019
Dec. 31, 2018
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
License agreements          
Upfront and immediate milestone payment to be received under license agreement $ 40.0        
Research and development expenses reimbursed     $ 5.4 $ 6.2  
Reimbursable costs included in accounts receivable     1.2 3.0  
Development and Regulatory Milestones          
License agreements          
Amount recognized and received for the achievement of a predefined milestone       $ 20.0  
Development and Regulatory Milestones | Maximum          
License agreements          
Upfront and immediate milestone payment to be received under license agreement   $ 129.0      
Development and Regulatory Milestones | PEMAZYRE          
License agreements          
Amount recognized and received for the achievement of a predefined milestone     $ 5.0    
Sales and Commercial Milestones | Maximum          
License agreements          
Upfront and immediate milestone payment to be received under license agreement         $ 202.5