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Concentrations of Credit Risk and Current Expected Credit Losses (Details)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Net Product Revenues | Customer Concentration Risk | Customer A      
Concentration of risk      
Percentage of concentration risk 20.00% 20.00% 20.00%
Net Product Revenues | Customer Concentration Risk | Customer B      
Concentration of risk      
Percentage of concentration risk 13.00% 13.00% 14.00%
Net Product Revenues | Customer Concentration Risk | Customer C      
Concentration of risk      
Percentage of concentration risk 17.00% 16.00% 15.00%
Net Product Revenues | Customer Concentration Risk | Customer D      
Concentration of risk      
Percentage of concentration risk 11.00% 11.00% 11.00%
Accounts Receivable | Credit Concentration Risk | Collaboration Partner A, B, C and D      
Concentration of risk      
Percentage of concentration risk 42.00% 30.00%  
Accounts Receivable | Credit Concentration Risk | Customer A, B, C and D      
Concentration of risk      
Percentage of concentration risk 29.00% 39.00%