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Revenues (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2020
Sep. 30, 2020
Jun. 30, 2020
Mar. 31, 2020
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Revenues                      
Total revenues $ 789,509 $ 620,643 $ 688,043 $ 568,507 $ 579,389 $ 551,581 $ 529,932 $ 497,857 $ 2,666,702 $ 2,158,759 $ 1,881,883
Product revenues, net                      
Revenues                      
Total revenues 559,500 522,300 500,300 486,700 490,800 454,000 433,900 396,200 2,068,736 1,774,922 1,466,900
JAKAFI                      
Revenues                      
Total revenues                 1,937,850 1,684,968 1,386,964
ICLUSIG                      
Revenues                      
Total revenues                 105,002 89,954 79,936
PEMAZYRE                      
Revenues                      
Total revenues                 25,884    
Product royalty revenues                      
Revenues                      
Total revenues 119,900 98,400 92,800 81,800 88,600 80,100 76,000 61,600 392,966 306,337 234,780
JAKAVI Royalty Revenues                      
Revenues                      
Total revenues                 277,902 225,913 194,694
OLUMIANT Royalty Revenues                      
Revenues                      
Total revenues                 110,920 80,424 40,086
TABRECTA Royalty Revenues                      
Revenues                      
Total revenues                 4,144    
Milestone and contract revenues                      
Revenues                      
Total revenues $ 110,000 $ 0 $ 95,000 $ 0 $ 0 $ 17,500 $ 20,000 $ 40,000 $ 205,000 $ 77,500 180,000
Other revenues                      
Revenues                      
Total revenues                     $ 203