Commitments and Contingencies

12 Months Ended

Dec. 31, 2017

Note 15. Commitments and Contingencies

Rent expense for all leases for the years ended December 31, 2017, 2016 and 2015, was approximately $8.2 million, $5.4 million and $1.3 million, respectively.

As of December 31, 2017, future non‑cancelable minimum payments under operating, direct financing and capital leases were as follows:


Year Ended December 31,	Operating Leases		Capital Lease
		(in millions)		(in millions)
2018	$	11.5	$	0.5
2019		6.2		0.1
2020		2.3		—
2021		0.7		—
2022		0.3		—
Thereafter		0.1		—
Total minimum lease payments	$	21.1	$	0.6

We lease approximately 160,000 square feet of office space in Chadds Ford, Pennsylvania, approximately 100,000 square feet of laboratory and office space in Wilmington, Delaware and approximately 63,000 square feet of office space in Europe and Japan.

We have entered into and may in the future seek to license additional rights relating to technologies or drug development candidates in connection with our drug discovery and development programs. Under these licenses, we may be required to pay upfront fees, milestone payments, and royalties on sales of future products, which are not reflected in the table above.