CONSOLIDATED STATEMENT OF STOCKHOLDERS' DEFICIT (Parenthetical)	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
CONSOLIDATED STATEMENT OF STOCKHOLDERS' DEFICIT
Issuance of shares of Common Stock upon exercise of stock options and restricted stock units	5,150,649	2,294,586	1,701,368
Issuance of shares of Common Stock under the ESPP	378,041	896,939	1,182,929
Issuance of shares of Common Stock upon conversion of convertible senio and subordinated notes, and Pfizer Note	1,461,496		1,502,851