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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 M1PnaUxBMXL+3fOa/SBx93q1JKFNsUcC1FHsSpnhrvXlxFrpS/FH39zkJ7X7/sLQ
 OU5V0rfMZXXA1JzC7I14YQ==

<SEC-DOCUMENT>0000950005-05-000657.txt : 20050923
<SEC-HEADER>0000950005-05-000657.hdr.sgml : 20050923
<ACCEPTANCE-DATETIME>20050923175926
ACCESSION NUMBER:		0000950005-05-000657
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050922
FILED AS OF DATE:		20050923
DATE AS OF CHANGE:		20050923

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HUMAN PHEROMONE SCIENCES INC
		CENTRAL INDEX KEY:			0000878616
		STANDARD INDUSTRIAL CLASSIFICATION:	PERFUMES, COSMETICS & OTHER TOILET PREPARATIONS [2844]
		IRS NUMBER:				943107202
		STATE OF INCORPORATION:			CA
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		84 WEST SANTA CLARA STREET
		STREET 2:		SUITE 720
		CITY:			SAN JOSE
		STATE:			CA
		ZIP:			95113
		BUSINESS PHONE:		4089383030

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EROX CORP
		DATE OF NAME CHANGE:	19940307

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Marx Robert
		CENTRAL INDEX KEY:			0001302370

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-23544
		FILM NUMBER:		051101424

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		408-938-3030

	MAIL ADDRESS:	
		STREET 1:		84 W. SANTA CLARA ST.
		STREET 2:		SUITE 720
		CITY:			SAN JOSE
		STATE:			CA
		ZIP:			95113
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>p19520_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-09-22</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000878616</issuerCik>
        <issuerName>HUMAN PHEROMONE SCIENCES INC</issuerName>
        <issuerTradingSymbol>EROX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001302370</rptOwnerCik>
            <rptOwnerName>Marx Robert</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>84 W. SANTA CLARA ST.</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 720</rptOwnerStreet2>
            <rptOwnerCity>SAN JOSE</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>95113</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Common Stock Options</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.40</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-09-22</value>
            </transactionDate>
            <deemedExecutionDate>
                <value>2005-09-22</value>
            </deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>20000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2005-09-22</value>
            </exerciseDate>
            <expirationDate>
                <value>2012-09-21</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Stock Options</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>20000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>83333</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <remarks>6  Options vest monthly over one year</remarks>

    <ownerSignature>
        <signatureName>/s/ William P. Horgan, as Attorney in Fact for Robert S. Marx</signatureName>
        <signatureDate>2005-09-23</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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