SECURITIES AND EXCHANGE COMMISSION
                            WASHINGTON, D.C. 20549
                                 SCHEDULE 13D
                   UNDER THE SECURITIES EXCHANGE ACT OF 1934

                               (Amendment No. 7)

                          OPHTHALMIC IMAGING SYSTEMS
                               (Name of Issuer)

                          COMMON STOCK, NO PAR VALUE
                        (Title of Class of Securities)

                                    683737
                                (CUSIP Number)

                          Premier Laser Systems, Inc.
                             Attn: Colette Cozean
                                3 Morgan Avenue
                               Irvine, CA 92718

                                with a copy to:

                            Peter J. Tennyson, Esq.
                           William J. Simpson, Esq.
                     Paul, Hastings, Janofsky & Walker LLP
                      695 Town Center Drive, 17/th/ Floor
                         Costa Mesa, California 92626
                                (714) 668-6200

                 (Name, address and telephone number of person
               authorized to receive notices and communications)

                                August 21, 1998
                     (Date of Event Which Requires Filing
                              of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report
the acquisition which is the subject of this Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following box [ ].

Note: Six copies of this statement, including all exhibits, should be filed with
the Commission. See Rule 13d-1(a) for other parties to whom copies are to be
sent.

- ------------------------------
* The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

                              (Page 1 of 5 Pages)

 
                        (Continued on following pages)
CUSIP No. 683737                      13D                      Page 2 of 5 Pages

1.   NAME OF REPORTING PERSON
     I.R.S. IDENTIFICATION NOS. OF ABOVE PERSON

     PREMIER LASER SYSTEMS, INC.
     33-0472684

2.   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                           a[ ]
                                                           b[X]
3.   SEC USE ONLY

4.   SOURCE OF FUNDS*
 
     WC

5.   CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS
     2(d) or 2(e)                                           [ ]

6.   CITIZENSHIP OR PLACE OF ORGANIZATION
 
     CALIFORNIA
 
NUMBER OF         7.   SOLE VOTING POWER
SHARES
BENEFICIALLY           2,131,758
OWNED BY
EACH              8.   SHARED VOTING POWER
REPORTING
PERSON                         0
WITH
                  9.   SOLE DISPOSITIVE POWER

                       2,131,758

                  10.  SHARED DISPOSITIVE POWER

                               0

11.  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     2,131,758

 
CUSIP No. 683737                      13D                      Page 3 of 5 Pages

12.  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES  [ ]

     N/A

13.  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     51.3%, BASED ON 4,155,428 SHARES OF COMMON STOCK REPORTED AS OUTSTANDING AS
     OF July 14, 1998.

14.  TYPE OF PERSON REPORTING

     CO



                     *SEE INSTRUCTIONS BEFORE FILLING OUT

 
                                                               Page 4 of 5 Pages

                          OPHTHALMIC IMAGING SYSTEMS
                                 Common Stock

                                 SCHEDULE 13D

        This Amendment No. 7 (the "Amendment") amends and supplements the
Schedule 13D originally filed with the Securities and Exchange Commission (the
"Commission") on December 29, 1997 (the "Original Schedule 13D"), as previously
amended by Amendment No. 1 to the Original Schedule 13D filed with the
Commission on January 5, 1998, by Amendment No. 2 to the Original Schedule 13D
filed with the Commission on January 20, 1998, by Amendment No. 3 filed with the
Commission on February 12, 1998, by Amendment No. 4 filed with the Commission on
March 3, 1998, by Amendment No. 5 filed with the Commission on August 14, 1998
and by Amendment No. 6 filed with the Commission on August 20, 1998, with
respect to the purchase by PREMIER LASER SYSTEMS, INC. ("Premier") of shares of
common stock, no par value per share (the "Shares") of OPHTHALMIC IMAGING
SYSTEMS, a California corporation ("OISI") (as amended, the "Schedule 13D").
Capitalized terms used but not defined herein shall have the meanings given to
such terms in the Schedule 13D.

Item 4.  Purpose of Transaction.

         The response set forth in Item 4 of the Schedule 13D is hereby amended
as follows:

         The Acquisition Agreement between Premier and OISI dated February 25,
1998 has terminated, but negotiations between the parties are continuing.

Item 6.  Contracts, Arrangements, Understandings or Relationships With Respect
to Securities of the Issuer.

         This item as previously filed is amended and supplemented by
incorporating herein the additions to Item 4 made by this Amendment No. 7.

 
                                                               Page 5 of 5 Pages

                                   SIGNATURE

               After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true,
complete and correct.


Dated: August 21, 1998

                                         PREMIER LASER SYSTEMS, INC.


                                         By:  /s/ CHARLES J. OLSON
                                            ---------------------------   
                                         Name: Charles J. Olson
                                         Title: Chief Financial Officer