<ARTICLE>  5
<LEGEND>
This schedule contains summary financial information extracted from Neose
Technologies, Inc.'s Form 10-Q for the quarter ended September 30, 2000 and is
qualified in its entirety by reference to such financial statements.

<MULTIPLIER>  1,000

                                                         
<PERIOD-TYPE>                                               9-MOS
<FISCAL-YEAR-END>                                            DEC-31-2000
<PERIOD-END>                                                 SEP-30-2000
<CASH>                                                             3,815
<SECURITIES>                                                      92,286
<RECEIVABLES>                                                      1,417
<ALLOWANCES>                                                           0
<INVENTORY>                                                            0
<CURRENT-ASSETS>                                                  98,344
<PP&E>                                                            20,257
<DEPRECIATION>                                                     6,713
<TOTAL-ASSETS>                                                   116,997
<CURRENT-LIABILITIES>                                              3,735
<BONDS>                                                            6,200
<PREFERRED-MANDATORY>                                                  0
<PREFERRED>                                                            0
<COMMON>                                                             140
<OTHER-SE>                                                       106,922
<TOTAL-LIABILITY-AND-EQUITY>                                     116,997
<SALES>                                                                0
<TOTAL-REVENUES>                                                   4,299
<CGS>                                                                  0
<TOTAL-COSTS>                                                          0
<OTHER-EXPENSES>                                                  13,877
<LOSS-PROVISION>                                                       0
<INTEREST-EXPENSE>                                                   351
<INCOME-PRETAX>                                                  (6,364)
<INCOME-TAX>                                                           0
<INCOME-CONTINUING>                                              (6,364)
<DISCONTINUED>                                                         0
<EXTRAORDINARY>                                                        0
<CHANGES>                                                              0
<NET-INCOME>                                                     (6,364)
<EPS-BASIC>                                                        (.48)
<EPS-DILUTED>                                                      (.48)