-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, IHfcLMLsgaidpe2cLxJp5gZHK+uRjU98Ej0uPAQoymn/7pwT1Ll/L+IiilbHwiJo B+hZ5odn2i1/LDrcE9FA8Q== 0000893220-06-001983.txt : 20060906 0000893220-06-001983.hdr.sgml : 20060906 20060906083703 ACCESSION NUMBER: 0000893220-06-001983 CONFORMED SUBMISSION TYPE: 8-K PUBLIC DOCUMENT COUNT: 5 CONFORMED PERIOD OF REPORT: 20060901 ITEM INFORMATION: Entry into a Material Definitive Agreement ITEM INFORMATION: Completion of Acquisition or Disposition of Assets ITEM INFORMATION: Cost Associated with Exit or Disposal Activities ITEM INFORMATION: Financial Statements and Exhibits FILED AS OF DATE: 20060906 DATE AS OF CHANGE: 20060906 FILER: COMPANY DATA: COMPANY CONFORMED NAME: NEOSE TECHNOLOGIES INC CENTRAL INDEX KEY: 0000877902 STANDARD INDUSTRIAL CLASSIFICATION: MEDICINAL CHEMICALS & BOTANICAL PRODUCTS [2833] IRS NUMBER: 133549286 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 8-K SEC ACT: 1934 Act SEC FILE NUMBER: 000-27718 FILM NUMBER: 061075435 BUSINESS ADDRESS: STREET 1: 102 WITMER RD CITY: HORSHAM STATE: PA ZIP: 19044 BUSINESS PHONE: 2154415890 MAIL ADDRESS: STREET 1: 102 WITMER ROAD CITY: HORSHAM STATE: PA ZIP: 19044 FORMER COMPANY: FORMER CONFORMED NAME: NEOSE PHARMACEUTICALS INC DATE OF NAME CHANGE: 19950817 8-K 1 w24742e8vk.htm FORM 8-K NEOSE TECHNOLOGIES, INC. e8vk
 

 
 
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
PURSUANT TO SECTION 13 OR 15(d)
OF THE SECURITIES EXCHANGE ACT OF 1934
Date of Report (Date of Earliest Event Reported): September 1, 2006
Neose Technologies, Inc.
(Exact Name of Issuer as Specified in Charter)
         
Delaware   0-27718   13-3549286
         
(State or Other Jurisdiction of
Incorporation or Organization)
  (Commission File Number)   (I.R.S. Employer Identification
Number)
         
102 Witmer Road, Horsham, Pennsylvania   19044
     
(Address of Principal Executive Offices)   (Zip Code)
(215) 315-9000
(Registrant’s Telephone Number, Including Area Code)
 
 
(Former Name or Former Address, if Changed Since Last Report)
Check the appropriate box below if the Form 8-K is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
o    Written communications pursuant to Rule 425 under the Securities Act
 
o    Soliciting material pursuant to Rule 14a-12 under the Exchange Act
 
o    Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act
 
o    Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act
 
 

 


 

Item 1.01 — Entry into a Material Definitive Agreement.
     On September 5, 2006, Neose Technologies, Inc. (the “Company”) completed a transaction whereby the Company sold its facility at 102 Witmer Road in Horsham, Pennsylvania (the “Facility”) and certain pieces of equipment located in the facility (collectively, the “Conveyed Property”) for a cash purchase price of $21,042,800. The transaction occurred pursuant to a Purchase and Sale Agreement (the “Purchase Agreement”) with ARE-PA Region No. 6, LLC, an affiliate of Alexandria Real Estate Equities, Inc. (the “Purchaser”) entered into after the close of business on September 1, 2006. The Purchase Agreement provides that the Facility and Conveyed Property are being sold with no warranties on an “as-is, where-is” basis, and contains other terms and conditions customary to the sale of a similar facility.
     Concurrent with the execution of the Purchase Agreement, the Purchaser entered into a lease agreement with Auxilium Pharmaceuticals, Inc. (the “Tenant”) for the occupation of the Facility and use of the Conveyed Property (the “Lease”), the Company entered into a Post-Closing Property Access Agreement with Tenant (“Access Agreement”) and the Company, Tenant and Purchaser entered into a Consent to Property Access Agreement (“Consent Agreement”). Under the Access Agreement, the Company has the right, rent-free, to continue to occupy certain office and laboratory space in the Facility and use certain Conveyed Equipment until the Company can consolidate all of its operations in its leased facility at 102 Rock Road in Horsham, Pennsylvania or February 28, 2007, whichever is earlier. Under the terms of the Consent Agreement, Purchaser consents to the Company’s use of portions of the Facility and of certain Conveyed Equipment pursuant to the Access Agreement and agrees that the Company’s right to such use will not end in the event the Lease is terminated.  The Consent Agreement also provides that, in the event the Lease terminates or Tenant defaults on its obligations in the Lease, the Company will assume certain obligations of Tenant (but not the payment of rent) relating to the portions of the Facility it occupies.The Company has no other relationship with the Purchaser other than the Purchase Agreement and the Consent Agreement. In addition to the Access Agreement, the Company has agreed to allow Tenant to have limited access to the Facility and Conveyed Property prior to the entry into the agreements described above.
Item 2.01 — Completion of Acquisition or Disposition of Assets.
     The information set forth under Item 1.01 of this report is incorporated herein by reference.
Item 2.05 — Costs Associated with Exit or Disposal Activities.
     The Company also announced on September 5, 2006, that it was reducing the size of its workforce by approximately 25% contemporaneously with the sale of the Facility. On August 21, 2006, the Board of Directors authorized management, in its discretion, to enter into agreements to sell the Facility and, in that event, to implement the workforce reduction. Management decided on September 1, 2006 to enter into the agreements and implement the workforce reduction.
     After achieving the full benefits of the Facility sale and workforce reduction in the fourth quarter of 2006, the Company expects to realize annualized savings of between $6 million and $8 million. The Company estimates that it will incur employee severance and retention costs

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related to personnel of approximately $1 million. Most of the restructuring costs will be reflected in the Company’s operating results during the quarter ending September 30, 2006.
     The Company will consolidate its operations in its adjacent, leased 40,000 square foot facility in Horsham, which currently houses approximately half of its employees. The Company expects to spend approximately $3.5 million through the first quarter of 2007 to construct additional laboratory and office space in the leased facility. The Company will continue to occupy portions of the Witmer Road Facility under the terms of the Access Agreement until these renovations are complete, which is expected to be by February 2007.
Item 9.01 — Financial Statements and Exhibits.
         
          (c)
  Exhibits:   Reference is made to the Exhibit Index annexed hereto and made a part hereof.
Neose “Safe Harbor” Statement under the Private Securities Litigation Reform Act of 1995: Statements in this report regarding the Company’s business that are not historical facts are “forward-looking statements” that involve risks and uncertainties, including without limitation the risk that we will incur unexpected charges and/or delays in connection with the consolidation of operations to our leased facility, the risk that we will incur unexpected charges or will have unexpected expenditures related to the restructuring upon the completion of further analysis with respect to the restructuring generally and our assets specifically. For a discussion of additional risks and uncertainties concerning the Company, any of which could cause the Company’s actual results to differ from those contained in the forward-looking statement, see the section of the Company’s Annual Report on Form 10-K for the year ended December 31, 2005, entitled “Factors Affecting the Company’s Prospects” and discussions of potential risks and uncertainties in the Company’s subsequent filings with the SEC.

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Signatures
     Pursuant to the requirements of the Securities and Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, hereunto duly authorized.
         
  Neose Technologies, Inc.
 
 
Date: September 5, 2006  By:   /s/ A. Brian Davis    
    A. Brian Davis   
    Senior Vice President and Chief Financial Officer   

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Index to Exhibits
     
Exhibit No.   Description
Exhibit 2.1
  Purchase and Sale Agreement and Joint Escrow Instructions by and between ARE-PA Region No.6, LLC and Neose Technologies, Inc. dated September 1, 2006
 
   
Exhibit 10.1
  Post-Closing Property Access Agreement by and between Auxilium Pharmaceuticals, Inc. and Neose Technologies, Inc. dated September 1, 2006
 
   
Exhibit 10.2
  Consent to Property Access Agreement by and among ARE-PA Region No.6, LLC, Auxilium Pharmaceuticals, Inc. and Neose Technologies, Inc. dated September 1, 2006
 
   
Exhibit 99.1
  Press release dated September 5, 2006
 
   

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EX-2.1 2 w24742exv2w1.txt PURCHASE AND SALE AGREEMENT AND JOINT ESCROW INSTRUCTIONS Exhibit 2.1 102 WITMER ROAD, HORSHAM, PA PURCHASE AND SALE AGREEMENT AND JOINT ESCROW INSTRUCTIONS SEPTEMBER 1, 2006 BY AND BETWEEN ARE-PA REGION NO. 6, LLC, A DELAWARE LIMITED LIABILITY COMPANY "BUYER" AND NEOSE TECHNOLOGIES, INC., A DELAWARE CORPORATION "SELLER" (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 102 WITMER ROAD, HORSHAM, PA PURCHASE AND SALE AGREEMENT AND JOINT ESCROW INSTRUCTIONS THIS PURCHASE AND SALE AGREEMENT AND JOINT ESCROW INSTRUCTIONS (this "AGREEMENT") is made and entered into as of September 1, 2006 ("EXECUTION DATE"), by and between ARE-PA REGION NO. 6, LLC, a Delaware limited liability company ("BUYER"), and NEOSE TECHNOLOGIES, INC., a Delaware corporation ("SELLER"), for the purposes of setting forth the agreement of the parties and of instructing CHICAGO TITLE INSURANCE COMPANY ("ESCROW AGENT"), with respect to the transactions contemplated by this Agreement. RECITALS A. Upon and subject to the terms and conditions set forth in this Agreement, Seller desires to sell and Buyer desires to purchase the following (collectively, the "PROPERTY"): (i) the fee interest in that certain real property commonly known as 102 Witmer Road, located in the Township of Horsham, County of Montgomery, Commonwealth of Pennsylvania, as legally described on Exhibit A attached hereto, together with all rights, privileges and easements appurtenant thereto or used in connection therewith, including, without limitation, all minerals, oil, gas and other hydrocarbon substances thereon, all development rights, air rights, water, water rights and water stock relating thereto, all strips and gores, and all of Seller's right, title and interest in and to any streets, alleys, easements, rights-of-way, public ways, or other rights appurtenant, adjacent or connected thereto or used in connection therewith (collectively, the "LAND"); (ii) all buildings, improvements, structures and fixtures now or hereafter included or located on or in the Land (collectively, the "IMPROVEMENTS"), and all apparatus, equipment, appliances and other fixtures used in connection with the operation or occupancy of the Land and the Improvements, such as heating, air conditioning or mechanical systems and facilities used to provide any utility services, refrigeration, ventilation, waste disposal or other services now or hereafter located on or in the Land or the Improvements; (iii) Seller's right, title, and interest in all leases, licenses and other occupancy agreements covering the Land and Improvements (these leases, together with all amendments, modifications, extensions or supplements thereto or guarantees thereof, are collectively referred to in this Agreement as the "TENANT LEASES") (the Land, the Improvements and Seller's right, title, and interest in the Tenant Leases are sometimes hereinafter collectively referred to as the "REAL PROPERTY"); (iv) all tangible personal property, equipment and supplies (collectively, the "PERSONAL PROPERTY") now or hereafter owned by Seller and located on or about the Land or the Improvements or attached thereto or used in connection with the use, (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 1 102 WITMER ROAD, HORSHAM, PA operation, maintenance or repair thereof, including, without limitation, the personal property designated in Exhibit B but excluding the personal property designated on Exhibit B-1 attached hereto and further excluding any personal property that Seller and Auxilium Pharmaceuticals, Inc., a Delaware corporation ("AUXILIUM"), agree shall remain the property of Seller pursuant to the agreements that are the subject of the Consent (as defined below). To the extent available and in its possession, the Personal Property includes Seller's non-proprietary standard operating procedures specifically relating to the Land and the Improvements and the maintenance of the other Personal Property being conveyed by Seller to Buyer pursuant to this Agreement ("CONVEYED EQUIPMENT"), validation protocols for all Conveyed Equipment and facility systems, and equipment turnover packages and equipment history files relating to the Conveyed Equipment and facility systems ("TECHNICAL INFORMATION"); and (v) all intangible property (collectively, the "INTANGIBLE PROPERTY") now or hereafter owned by Seller and used in connection with the Land, the Improvements or the Personal Property (with the exception, however, of the Service Contracts [as defined below]), including, without limitation, transferable licenses, architectural, site, landscaping or other permits, applications, approvals, authorizations and other entitlements, transferable guarantees and warranties covering the Land and/or Improvements, books, records, reports, test results, environmental assessments, as-built plans, specifications and other similar documents and materials relating to the use or operation, maintenance or repair of the Property or the construction or fabrication thereof. The Intangible Property shall exclude any of the foregoing related to the business (including, but not limited to, any and all intellectual property) of Seller and not specifically related to the use and operations of the Land and the Improvements, all of which shall remain the sole property of Seller. B. Seller and Auxilium have entered into that certain letter agreement dated July 26, 2006 whereby Auxilium is granted certain rights to access and use of the Property (the "AUXILIUM ACCESS AGREEMENT"). C. Simultaneously with the execution and delivery of this Agreement (i) Seller, Buyer, and Auxilium have entered into a Consent to Property Access Agreements ("CONSENT"), and (ii) Buyer, as landlord, and Auxilium, as tenant, have entered into a lease of the Property (the "AUXILIUM LEASE") on terms and conditions acceptable to Buyer in the exercise of its sole and absolute discretion. D. The execution and delivery of this Agreement is conditioned upon the simultaneous execution and delivery of the Consent. NOW, THEREFORE, in consideration of the foregoing Recitals which are incorporated herein by this reference, the mutual covenants contained in this Agreement and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Buyer and Seller hereby agree, and instruct Escrow Agent, as follows: (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 2 102 WITMER ROAD, HORSHAM, PA 1 AGREEMENT TO PURCHASE AND SELL. Subject to all of the terms and conditions of this Agreement, Seller agrees to sell, transfer and convey to Buyer, and Buyer agrees to acquire and purchase from Seller, the Property upon the terms and conditions set forth herein. 2 PURCHASE PRICE. The purchase price for the Property (the "PURCHASE PRICE") shall be the sum of $21,050,000, payable as follows: 2.1 DEPOSIT. Not later than the date which is 3 Business Days (as hereinafter defined) after the Execution Date, Buyer shall deposit into Escrow the sum of $500,000 (which amount, together with any and all interest and dividends earned thereon, shall hereinafter be referred to as the "DEPOSIT"). Escrow Agent shall deposit the Deposit in a non-commingled trust account and shall invest the Deposit in insured money market accounts, certificates of deposit, United States Treasury Bills or such other instruments as Buyer may instruct from time to time. In the event of the consummation of the purchase and sale of the Property as contemplated hereunder, the Deposit shall be paid to Seller at the Closing (as defined in Section 8 below) and credited against the Purchase Price. If Buyer does not elect to terminate this Agreement pursuant to Section 3.5 (Termination Right) before the Due Diligence Termination Date, the Deposit shall automatically become non-refundable unless (a) the Closing fails to occur by reason of Seller's default, (b) Buyer terminates the Agreement in accordance with Article 12 (Risk of Loss), or (c) any other provision under this Agreement entitles Buyer to a refund of the Deposit (including, but not limited to, Section 7.3 [Failure of Condition Precedent]). 2.2 BALANCE. On the Closing Date (as defined below), Buyer shall pay to Seller the balance of the Purchase Price over and above the Deposit paid by Buyer under Section 2.1 above, by wire transfer of federal funds to Escrow Agent, net of all prorations and adjustments as provided herein. 3 DUE DILIGENCE 3.1 PROPERTY DOCUMENTS. Buyer acknowledges that it received from Seller all the materials listed on Exhibit C attached hereto (the "PROPERTY DOCUMENTS") 3.2 INVESTIGATIONS. 3.2.1 At all reasonable times from the Execution Date until the Closing or earlier termination of this Agreement and upon no less than 24 hours prior notice to Seller, Buyer, its agents and representatives shall be entitled at Buyer's sole cost and expense to (i) enter onto the Property during normal business hours to (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 3 102 WITMER ROAD, HORSHAM, PA perform any inspections, investigations, studies and tests of the Property, including, without limitation, physical, structural, mechanical, architectural, engineering, soils, geotechnical and environmental/asbestos tests that Buyer deems reasonable provided that no intrusive testing shall be performed at the Property unless a work plan for same is approved by Seller (which approval shall not be unreasonably withheld, delayed, or conditioned); (ii) cause an environmental assessment of the Property to be performed; (iii) review all Property Documents and examine and copy any and all other books and records in the possession or control of Seller or its agents relating to the Property (including, without limitation, all documents relating to utilities, zoning, and the access, subdivision and appraisal of the Property); and (iv) interview Seller's personnel responsible for the operation and management of the Property. Buyer shall conduct the investigations in such a manner that it shall not in any way damage the Property, create a hazardous or dangerous condition, necessitate a repair or clean-up, and/or deposit or release any Environmental Materials (as defined below) at, on or under the Property, or unreasonably interfere with Seller's normal business operations or security requirements. If approved by Seller, prior to performing any intrusive testing on the Property, Buyer shall provide Seller with copies of Buyer's plans as to the scope and methodology of work relating to such intrusive testing. Buyer shall give Seller and its respective authorized agents the opportunity, at Buyer's cost, to split samples taken from the Property. Buyer shall be responsible for locating any utilities on the Property and marking same; provided, however, that Seller shall assist Buyer in locating the utilities and shall provide Buyer with any documentation in its possession or control in connection herewith. 3.2.2 In connection with any investigations, Buyer will not permit the attachment of any mechanic's lien, materialmen's lien, or any other lien, claim, or encumbrance ("ENCUMBRANCE") against the Property. In the event of such Encumbrance, Buyer shall bear all cost and expense related to the defense or removal of same and indemnify and hold Seller harmless from any cost or expense (including reasonable attorneys' fees) that Seller may incur in connection therewith. 3.2.3 Buyer shall take all commercially reasonable precautions to prevent damage to the Property or personal property of Seller. 3.3 CC&RS. Buyer may conduct such inquiries and investigations of any and all declarants or associations created by any covenants, conditions or restrictions encumbering the Property ("CC&RS") as Buyer, in its sole and absolute discretion, deems advisable or necessary. Not later than 3 Business Days before the Closing Date (subject to extension pursuant to the provisions of Section 8.1 [Closing Date]), Seller shall use commercially reasonable efforts to deliver to Buyer an estoppel certificate, each substantially in form and substance acceptable to Buyer, executed by each declarant or association under any (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 4 102 WITMER ROAD, HORSHAM, PA CC&Rs (collectively, the "CC&RS ESTOPPELS"). The form of the CC&Rs Estoppel is attached hereto as a part hereof as Exhibit J. 3.4 PROPERTY QUESTIONNAIRE. Seller has completed the property questionnaire attached hereto as Exhibit D (the "PROPERTY QUESTIONNAIRE") but in doing so has answered each question therein as if the agreements that are the subject of the Consent have not been executed and do not affect the Property or Seller. 3.5 TERMINATION RIGHT. Buyer shall have the right at any time on or before 5:00 p.m. (Los Angeles, California time) on Friday, August 18, 2006 (the "DUE DILIGENCE TERMINATION DATE") to terminate this Agreement if, during the course of Buyer's due diligence investigations of the Property, Buyer determines in its sole and absolute discretion that the Property is not acceptable to Buyer. Buyer may exercise such termination right by delivering written notice of termination to Seller and Escrow Agent (a "DUE DILIGENCE TERMINATION NOTICE") on or before the Due Diligence Termination Date. Upon the timely delivery of such Due Diligence Termination Notice, (i) Escrow Agent shall immediately return the Deposit to Buyer and (ii) this Agreement shall automatically terminate and be of no further force or effect and neither party shall have any further rights or obligations hereunder, other than pursuant to any provision hereof which expressly survives the termination of this Agreement. If Buyer has timely delivered to Escrow Agent a Due Diligence Termination Notice, no notice to Escrow Agent from Seller shall be required for the return of the Deposit to Buyer. If Buyer does not exercise such termination by delivery of the Due Diligence Termination Notice on or before the Due Diligence Termination Date, then Buyer's right to terminate this Agreement pursuant to this Section shall automatically lapse. 3.6 INSURANCE. Buyer agrees that from the Execution Date through the Due Diligence Termination Date, Buyer shall carry, or cause its agents and representatives that will enter the Property in connection with the investigations pursuant to Section 3.2 to carry, workers' compensation and commercial general liability insurance, including contractual liability insurance and property damage insurance, under policies issued by insurers licensed to conduct business in Pennsylvania with per occurrence limits of not less than $2,000,000 for bodily injury, or death and damage to or destruction of property (including the loss of use thereof), and $4,000,000 combined aggregate, and workers' compensation at statutory limits. Additionally, Buyer or its contractors, as applicable, shall provide the following coverages: Automobile liability insurance for all owned, non-owed, leased or hired vehicles with not less than $2,000,000 combined single limit, and contractor's pollution liability with limits of $1,000,000 per occurrence and $2,000,000 aggregate. Such policies shall name Seller and its agents, and employees as additional insureds, as their interests appear under this Agreement. On written request from Seller, Buyer shall deliver to Seller certificates of insurance evidencing such coverage prior to entering upon the Property. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 5 102 WITMER ROAD, HORSHAM, PA 3.7 INDEMNITY AND REPAIR. Buyer agrees to indemnify and hold harmless Seller from any losses arising from any actual damage to the Property or any injury to persons caused by any act of Buyer as a result of the inspections, investigations or tests performed pursuant to Section 3.2 above, which indemnity shall survive the termination of this Agreement or the Closing for a period of 180 days; provided, however, that Buyer's indemnity hereunder shall not include any losses, cost, damage or expenses resulting from (x) the acts of Seller, its agents or representatives unless at the specific direction of Buyer, or (y) the discovery of any pre-existing condition of the Property. In addition, if this Agreement is terminated, Buyer shall repair any damage to the Property caused by its entry thereon and shall restore the Property substantially to the condition in which it existed prior to such entry; provided, however, that Buyer shall have no obligation to repair any damage caused by the acts or omissions of Seller, its agents or representatives or to remediate, contain, abate or control any pre-existing condition of the Property which existed prior to Buyer's entry thereon except and to the extent exacerbated due to the gross negligence or willful misconduct of Buyer. 3.8 TITLE. 3.8.1 DELIVERIES BY SELLER. Not later than 10 days after the Execution Date, Buyer shall order (a) an ALTA extended coverage preliminary title report (the "PTR") issued by Chicago Title Insurance Company (in such capacity, "TITLE COMPANY"), together with legible copies of all documents referenced as exceptions therein, (b) a current As-Built American Land Title Association survey of the Property (the "SURVEY"), in form reasonably satisfactory to Buyer and Title Company, prepared by a surveyor licensed in the Commonwealth of Pennsylvania and certified (using a surveyor's certificate in substantially the same form as the certificate attached hereto as Exhibit E) to Buyer, Title Company, and such other persons or entities as Buyer may, in its discretion, request; and (c) a UCC Search with regard to Seller and the Property (the "UCC SEARCH"). 3.8.2 BUYER'S REVIEW OF TITLE. Buyer shall have until the Due Diligence Termination Date to notify Seller in writing of any objection which Buyer may have to any exception reported in the PTR or matter shown on the Survey or the UCC Search or any updates thereof; provided, however, that if any such updates are received by Buyer, Buyer shall have an additional 5 Business Days, regardless of the Due Diligence Termination Date or Closing Date, following Buyer's receipt of such update and legible copies of all documents referenced therein to notify Seller of objections to items shown on any such update and not shown on the original PTR or Survey because such documents were not of record at the time of the original PTR or Survey. Exceptions reported in the PTR and matters shown on the Survey or the UCC Search (or any updates thereof) not objected to by Buyer as provided above shall be deemed to be "PERMITTED EXCEPTIONS." (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 6 102 WITMER ROAD, HORSHAM, PA 3.8.3 SELLER'S OBLIGATIONS REGARDING TITLE. As a condition to Closing, Seller shall take all action necessary to remove from title to the Property (or in the alternative, Seller shall obtain for Buyer title insurance insuring over such exceptions or matters, such insurance to be in form and substance satisfactory to Buyer in its sole and absolute discretion) the following matters: (a) all exceptions to title and survey matters created by Seller on or after the Execution Date without the prior written consent of Buyer (which consent may be withheld in Buyer's sole and absolute discretion); (b) any and all liens and encumbrances affecting the Property which secure an obligation to pay money (other than installments of real estate taxes or assessments not delinquent as of the Closing); provided, however, that Seller shall not be required to cause judgment liens to be removed if such liens exceed an amount equal to $5,000,000; and (c) all taxes and assessments due and payable for any period prior to the Closing (collectively, the "OBLIGATORY REMOVAL EXCEPTIONS"). If, prior to the Closing, Seller is unable to remove or satisfactorily insure over any of the Obligatory Removal Exceptions, then, in addition to any and all other rights and remedies which Buyer may have hereunder, Buyer may (a) terminate this Agreement by delivering written notice to Seller and Escrow Agent (in which case Escrow Agent shall immediately return the Deposit to Buyer), and Seller shall reimburse Buyer for all of Buyer's out-of-pocket costs and expenses in an aggregate amount not to exceed $100,000 incurred in connection with the transaction contemplated by this Agreement (including, but not limited to, costs incurred to negotiate the Auxilium Lease), and thereafter neither party shall thereafter have any rights or obligations to the other hereunder, other than pursuant to any provision hereof which expressly survives the termination of this Agreement; (b) pursue an action for specific performance to compel Seller to remove the Obligatory Removal Exceptions; or (c) waive Buyer's objections to such Obligatory Removal Exceptions and proceed to a timely Closing whereupon such Obligatory Removal Exceptions shall be deemed "PERMITTED EXCEPTIONS." If, prior to the Closing, Seller is unable to remove or satisfactorily insure over any other exceptions or matters objected to by Buyer (other than Obligatory Removal Exceptions), then, in addition to any and all other rights and remedies which Buyer may have hereunder, Buyer may (x) terminate this Agreement by delivering written notice to Seller and Escrow Agent (in which case Escrow Agent shall immediately return the Deposit to Buyer) and thereafter neither party shall thereafter have any rights or obligations to the other hereunder, other than pursuant to any provision hereof which expressly survives the termination of this Agreement; or (y) waive Buyer's objections to such other exceptions and matters (other than Obligatory Removal Exceptions) and proceed to a timely Closing whereupon such other exceptions and matters shall be deemed "PERMITTED EXCEPTIONS." 3.8.4 CONDITION OF TITLE AT CLOSING. Upon the Closing, Seller shall sell, transfer and convey to Buyer indefeasible fee simple title to the Land and the Improvements (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 7 102 WITMER ROAD, HORSHAM, PA thereon by a duly executed and acknowledged deed in the form of Exhibit F attached hereto (the "DEED"), subject only to the Permitted Exceptions. 4 SELLER'S REPRESENTATIONS AND WARRANTIES. Seller represents and warrants to and agrees with Buyer that, as of the Execution Date and as of the Closing Date: 4.1 AUTHORITY. This Agreement and all other documents delivered prior to or at the Closing (i) have been duly authorized, executed, and delivered by Seller; (ii) are binding obligations of Seller; and (iii) do not violate the formation documents of Seller. Seller has obtained all required consents, releases, and approvals necessary to execute this Agreement and consummate the transaction contemplated by this Agreement. Seller further represents that it is a corporation, duly organized and existing in good standing under the laws of the State of Delaware, with its principal place of business in Pennsylvania. 4.2 NO CONFLICTS. The execution and delivery of this Agreement, the consummation of the transactions herein contemplated, and compliance with the terms of this Agreement will not conflict with, or, with or without notice or the passage of time or both, result in a breach of any of the terms or provisions of, or constitute a default under, any indenture, deed of trust, mortgage, loan agreement, or other document, or instrument or agreement, oral or written, to which Seller is a party or by which Seller or the Property is bound, or any applicable regulation of any governmental agency, or any judgment, order or decree of any court having jurisdiction over Seller or all or any portion of the Property. 4.3 PREFERENTIAL RIGHTS. Seller has not granted any options or rights of first refusal or rights of first offer to third parties to purchase or otherwise acquire an interest in the Property other than such rights of entry as may exist in favor of Auxilium pursuant to the Pre-Closing Property Access Agreement of even date herewith between Auxilium and Seller. 4.4 PROPERTY DOCUMENTS. The Property Documents required to be delivered by Seller pursuant to the terms hereof constitute all of the material documents relating to the Property, and each such Property Document as delivered by Seller constitutes a true, correct and complete copy of such Property Document. To Seller's Knowledge, there are no commitments or agreements affecting the Property to which Seller is a party which would constitute a material document which have not been disclosed by Seller to Buyer in writing. Seller is not in default of Seller's obligations or liabilities pertaining to the Property or the Property Documents; nor, to Seller's Knowledge, are there facts, circumstances, conditions, or events which, after notice or lapse of time, would constitute a default. Seller has not received notice or information that any party to any of the Property Documents considers a breach or default to have occurred. Seller has delivered to Buyer on or before the Execution Date Seller's executed counterpart of the Consent. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 8 102 WITMER ROAD, HORSHAM, PA 4.5 NO TENANT LEASES. There are no Tenant Leases, no third party has the right to occupy space at the Property, and there are no other documents or agreements binding upon the Property or Buyer after the Closing with respect to the rights and obligations of such third parties relating to the Property other than the rights of Seller and Auxilium as provided in the agreements that are the subject of the Consent. 4.6 UNPAID COMMISSIONS. As of the Closing Date, there will be no brokerage or other leasing commissions due or payable on an absolute or contingent basis to any person in connection with any new Tenant Lease other than with respect to the Auxilium Lease, which commissions shall be paid at Closing by Seller. 4.7 SPECIAL ASSESSMENTS OR CONDEMNATION. To Seller's Knowledge, there are no existing, proposed or contemplated (i) special assessments, except those shown as exceptions on the PTR, or (ii) condemnation actions against the Property or any part, and Seller has not received written notice of any contemplated special assessments or eminent domain proceedings that would affect the Property. 4.8 UTILITIES. Seller has received no notices that service for water, sewer, electric, gas, telephone, and drainage facilities, and all other utilities required by law or for the normal operation of the Property, will be disconnected or reduced. 4.9 SERVICE CONTRACTS. There are no service, maintenance, repair, management, leasing, or supply contracts or other contracts (including, without limitation, janitorial, elevator, and landscaping agreements) affecting the Property, oral or written ("SERVICE CONTRACTS"), by or on behalf of Seller that will bind the Property or Buyer after the Closing Date. 4.10 EMPLOYEES. On and after the Closing, there will be no obligations concerning any pre-Closing employees of Seller that will be binding upon Buyer or the Property. 4.11 BANKRUPTCY. No attachments, execution proceedings, assignments for the benefit of creditors, insolvency, bankruptcy, reorganization or other proceedings are pending, or, to Seller's Knowledge, threatened, against Seller. 4.12 INSURANCE. There are currently in effect such insurance policies as are customarily maintained with respect to similar properties. Seller has received no written notice from any insurance company concerning, nor, to Seller's Knowledge, are there any defects or inadequacies in the Property which, if not corrected, would result in the termination of insurance coverage or increase its cost. 4.13 LITIGATION. There are no actions, suits or proceedings before any judicial or quasi-judicial body, pending, or to Seller's Knowledge, threatened, against or affecting all or any portion of the Property. 4.14 COMPLIANCE WITH LAWS. Seller has received no written notice of, and has no Knowledge of, any condition currently or previously existing on the Property or any portion thereof (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 9 102 WITMER ROAD, HORSHAM, PA that may give rise to any violation of any existing laws, rules, regulations, ordinances and orders of all applicable federal, state, city and other governmental authorities in effect as of the date of this Agreement (collectively, "LAWS"), including, without limitation, all Laws with respect to zoning, building, fire and health codes, environmental protection and sanitation and pollution control and the Americans with Disabilities Act, as amended, applicable to the Property if it were disclosed to the authorities having jurisdiction over the Property. 4.15 ENVIRONMENTAL MATERIALS. 4.15.1 DEFINITIONS. (A) "ENVIRONMENTAL CLAIM" means any and all actions (including, without limitation, investigatory, remedial or enforcement actions of any kind, administrative or judicial proceedings, and orders or judgments arising out of or resulting therefrom), costs, claims, damages (including, without limitation, punitive damages), expenses (including, without limitation, attorneys', consultants' and experts' fees, court costs and amounts paid in settlement of any claims or actions), fines, forfeitures or other civil, administrative or criminal penalties, injunctive or other relief (whether or not based upon personal injury, property damage, or contamination of, or adverse effects upon, the environment, water tables or natural resources), liabilities or losses arising from or relating to the presence or suspected presence of any Environmental Materials in, on, under, or about the Property or properties adjacent thereto. (B) "ENVIRONMENTAL MATERIALS" means chemicals, pollutants, contaminants, wastes, toxic substances, petroleum and petroleum products or any other chemical, material, or substance that, because of its quantity, concentration, or physical or chemical characteristics, exposure to which is limited or regulated for health and safety reasons by any governmental authority, or which poses a significant present or potential hazard to human health and safety or to the environment if released into the workplace or the environment. 4.15.2 REPRESENTATIONS AND WARRANTIES. Seller represents and warrants to and agrees with Buyer that, as of the Execution Date and as of the Closing Date: (i) to Seller's Knowledge, each of the Property and Seller is in full compliance with all Laws relating to Environmental Materials, which compliance includes, but is not limited to, the possession by Seller of all permits and other governmental authorities required under applicable Laws, and compliance with the terms and conditions thereof; (ii) Seller has not received any written communication that alleges that Seller or the Property is not in such full compliance; (iii) there is no Environmental Claim pending or, to Seller's Knowledge, threatened with regard to the Property; and (iv) without in any way limiting the generality of the foregoing, (a) Seller has not used, stored, generated, released, disposed or (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 10 102 WITMER ROAD, HORSHAM, PA arranged for the disposal of Environmental Materials on the Property except in compliance with Law, (b) no underground storage tanks were installed or removed on or from the Property during Seller's period of ownership of the Property, (c) except for 1 underground storage tank that was capped, to Seller's Knowledge, no underground storage tanks were installed or removed on or from the Property before Seller's period of ownership of the Property, (d) to Seller's Knowledge, there is no asbestos contained in or forming part of any Improvement, including, without limitation, any building, building component, structure or office space on the Property, and (e) to Seller's Knowledge, no polychlorinated biphenyls (PCBs) are used or stored at the Property. 4.15.3 INDEMNIFICATION. Seller hereby indemnifies and agrees to reimburse, defend (with counsel reasonably acceptable to Buyer), and hold Buyer harmless from, for and against all Environmental Claims arising from, asserted against, imposed on, or incurred by Buyer, directly or indirectly, in connection with the breach of any representation or warranty set forth in Section 4.15.2 of this Agreement. If an Environmental Claim is made against Buyer covered by the indemnity under this Section 4.15.3, Buyer shall promptly give notice to Seller, with a copy of the claim, demand, arbitration, or litigation documents. Buyer shall reasonably cooperate with Seller, including, without limitation, giving testimony at depositions and/or hearings. If Buyer desires to have its own counsel monitor any such proceedings, it may do so, at its expense, but Seller's counsel shall be the only counsel of record. 4.16 PERSONAL PROPERTY. Seller has good and marketable title to the Personal Property and shall convey same at Closing, free and clear of all liens, mortgages, pledges, security interests, prior assignments, encumbrances, and claims of any nature other than the Permitted Exceptions. Seller has made available at the Property for Buyer's inspection and review the Technical Information in form and content maintained by Seller in the ordinary course of its business. 4.17 SURVIVAL. All of the representations, warranties and agreements of Seller set forth in this Agreement shall be true upon the execution of this Agreement, shall be deemed to be repeated at and as of the Closing Date without the necessity of a separate certificate with respect thereto and shall survive the delivery of the Deed and other Closing instruments and documents for a period of 18 months. 4.18 SELLER'S KNOWLEDGE. As used in this Agreement, the phrase "TO SELLER'S KNOWLEDGE," "KNOWLEDGE," and words of similar import shall mean the actual knowledge of H. James White, Seller's Director of BioEngineering and Facilities and A. Brian Davis, Senior Vice President and Chief Financial Officer without independent investigation. Seller represents and warrants that the foregoing persons are those persons affiliated with Seller most knowledgeable regarding the ownership and operation of the Property. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 11 102 WITMER ROAD, HORSHAM, PA 4.19 AS-IS. Except as expressly set forth herein, including, without limitation elsewhere in this Article 4, and except for those warranties, expressly set forth in the Deed or other documents delivered at the Closing, Seller shall convey the Property to Buyer in its present "AS-IS" condition, without any warranties, expressed or implied. EXCEPT AS EXPRESSLY SET FORTH IN THIS AGREEMENT AND CERTAIN OF THE DOCUMENTS TO BE DELIVERED IN CONNECTION WITH CLOSING, (A) SELLER HAS NOT MADE AND DOES NOT HEREBY MAKE ANY REPRESENTATIONS, WARRANTIES OR OTHER STATEMENTS AS TO THE CONDITION OF THE PROPERTY, (B) BUYER ACKNOWLEDGES THAT AT CLOSING IT IS PURCHASING THE PROPERTY ON AN "AS IS, WHERE IS" BASIS AND WITHOUT RELYING ON ANY REPRESENTATIONS AND WARRANTIES OF ANY KIND WHATSOEVER, EXPRESS OR IMPLIED, FROM SELLER, ITS AGENTS OR BROKERS AS TO ANY MATTERS CONCERNING THE PROPERTY, AND (C) NO REPRESENTATIONS OR WARRANTIES HAVE BEEN MADE OR ARE MADE AND NO RESPONSIBILITY HAS BEEN OR IS ASSUMED BY SELLER OR BY ANY PARTNER, OFFICER, PERSON, FIRM, AGENT OR REPRESENTATIVE ACTING OR PURPORTING TO ACT ON BEHALF OF SELLER AS TO THE CONDITION OR REPAIR OF THE PROPERTY OR THE VALUE, EXPENSE OF OPERATION, OR INCOME POTENTIAL THEREOF OR AS TO ANY OTHER FACT OR CONDITION THAT HAS OR MIGHT AFFECT THE PROPERTY OR THE CONDITION, REPAIR, VALUE, EXPENSE OF OPERATION OR INCOME POTENTIAL OF THE PROPERTY OR ANY PORTION THEREOF. THE PARTIES HERETO AGREE THAT ALL UNDERSTANDINGS AND AGREEMENTS HERETOFORE MADE BETWEEN THEM OR THEIR RESPECTIVE AGENTS OR REPRESENTATIVES ARE MERGED IN THIS AGREEMENT AND THE EXHIBITS ATTACHED HERETO, WHICH ALONE FULLY AND COMPLETELY EXPRESS THEIR AGREEMENT, AND THAT THIS AGREEMENT HAS BEEN ENTERED INTO AFTER FULL INVESTIGATION, OR WITH THE PARTIES SATISFIED WITH THE OPPORTUNITY AFFORDED FOR INVESTIGATION, NEITHER PARTY RELYING UPON ANY STATEMENT OR REPRESENTATION BY THE OTHER UNLESS SUCH STATEMENT OR REPRESENTATION IS SPECIFICALLY EMBODIED IN THIS AGREEMENT OR THE EXHIBITS ATTACHED HERETO OR CERTAIN OF THE DOCUMENTS TO BE DELIVERED IN CONNECTION WITH CLOSING. 5 BUYER'S REPRESENTATIONS AND WARRANTIES. Buyer represents and warrants to and agrees with Seller that, as of the Execution Date, and as of the Closing Date: 5.1 NO CONFLICTS. The execution and delivery of this Agreement, the consummation of the transactions herein contemplated, and compliance with the terms of this Agreement will not conflict with, or, with or without notice or the passage of time or both, result in a breach of any of the terms or provisions of, or constitute a default under, any indenture, deed of trust, mortgage, loan agreement, or other document or instrument to which Buyer is a party or by which Buyer is bound, or any applicable regulation of any governmental agency, or any judgment, order or decree of any court having jurisdiction over Buyer or all or any portion of the Property. 5.2 DUE ORGANIZATION; CONSENTS. Buyer is a limited liability company duly formed and existing in good standing under the laws of the State of Delaware with its principal place (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 12 102 WITMER ROAD, HORSHAM, PA of business in the State of California. All requisite limited partnership action has been taken by Buyer in connection with entering into this Agreement, and will be taken prior to the Closing in connection with the execution and delivery of the instruments referenced herein and the consummation of the transactions contemplated hereby. No consent of any member, partner, shareholder, beneficiary, creditor, investor, judicial or administrative body, governmental authority or other party is required in connection herewith which has not been obtained, except with respect to the consent of the Board of Directors of the parent company of Buyer, which consent shall be obtained or denied prior to the expiration of the Due Diligence Termination Date. 5.3 BUYER'S AUTHORITY; VALIDITY OF AGREEMENTS. Buyer has or will have prior to the Closing full right, power and authority to purchase the Property from Seller as provided in this Agreement and to carry out its obligations hereunder. The individual(s) executing this Agreement and the instruments referenced herein on behalf of Buyer have the legal power, right and actual authority to bind Buyer to the terms hereof and thereof. This Agreement is and all other documents and instruments to be executed and delivered by Buyer in connection with this Agreement have been duly authorized, executed and delivered by Buyer and shall be valid, binding and enforceable obligations of Buyer. 5.4 AUXILIUM LEASE. Buyer and Auxilium have entered into the Auxilium Lease, which constitutes a lease for the entire Property that commences as of Closing and expires more than 1 year thereafter. 6 COVENANTS OF SELLER. In addition to the covenants and agreements of Seller set forth elsewhere in this Agreement, Seller covenants and agrees that between the Execution Date and the Closing Date: 6.1 TITLE. Seller shall not (a) directly or indirectly sell, assign or create any right, title or interest whatsoever in or to the Property, (b) take any action, create, commit, permit to exist or suffer any acts which would (i) give rise to a variance from the current legal description of the Land, or (ii) cause the creation of any lien, charge or encumbrance other than the Permitted Exceptions, or (c) enter into any agreement to do any of the foregoing without Buyer's prior written consent (which consent may be withheld in Buyer's sole and absolute discretion), other than the agreements that are the subject of the Consent. Seller shall comply with the terms and conditions of the Consent. 6.2 NOTICE OF CHANGE IN CIRCUMSTANCES. Seller shall promptly notify Buyer of any change in any condition with respect to the Property or any portion thereof or of any event or circumstance of which Seller has Knowledge subsequent to the date of this Agreement which (a) materially, adversely affects the Property or any portion thereof or the use or operation of the Property or any portion thereof, (b) makes any representation or warranty of Seller to Buyer under this Agreement untrue or misleading, or (c) makes any covenant or agreement of Seller under this Agreement incapable or less likely of being performed, it being expressly understood that Seller's obligation to provide information to Buyer (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 13 102 WITMER ROAD, HORSHAM, PA under this Section shall in no way relieve Seller of any liability for a breach by Seller of any of its representations, warranties, covenants or agreements under this Agreement. 6.3 NO DEFAULTS; MAINTENANCE OF PROPERTY. Seller shall not default with respect to the performance of any obligation relating to the Property, including, without limitation, the payment of all amounts due and the performance of all obligations with respect to the Service Contracts and any existing indebtedness relating to the Property. Subject to Section 12, Seller shall operate and maintain the Property in its current condition, reasonable wear and tear excepted, in accordance with all applicable Laws. 6.4 EXCLUSIVE NEGOTIATIONS. Seller shall (i) remove the Property from the market, (ii) cease and refrain from any and all negotiations with any other prospective optionees or purchasers of the Property, and (iii) advise Buyer of any negotiations with current or potential tenants at the Property. 6.5 DEVELOPMENT ACTIVITIES. Except as may be required under the Consent, Seller shall not take any actions with respect to the development of the Property, including, without limitation, applying for, pursuing, accepting or obtaining any permits, approvals or other development entitlements from any governmental or other regulatory entities or finalizing or entering into any agreements relating thereto without Buyer's prior written consent (which consent may be withheld in Buyer's sole and absolute discretion). Seller hereby agrees to reasonably cooperate with Buyer in Buyer's efforts to obtain such governmental approvals as Buyer deems necessary to permit Buyer to operate the Property as Buyer wishes, although obtaining such approvals shall not be a condition to Closing. 6.6 SERVICE, MANAGEMENT AND EMPLOYMENT CONTRACTS. Seller shall not enter into, extend, renew or replace any existing service, property management or employment contracts in respect of the Property that will be binding on the Property or Buyer after Closing without Buyer's prior written consent (which consent may be withheld in Buyer's sole and absolute discretion), unless the same shall be cancelable without penalty or premium, upon not more than 30 days' notice from the owner of the Property and Seller shall immediately notify Buyer of any such new, extended, renewed or replaced contract. Seller shall take all necessary steps to either terminate the Service Contracts on or prior to Closing or to cause the Service Contracts to which Seller is a party to be assigned to and assumed by Auxilium effective as of Closing. 6.7 TENANT LEASES. Except as set forth in the Consent, Seller shall not negotiate with any potential tenant of the Property or enter into any Tenant Lease. 6.8 INSURANCE. Seller will maintain its current insurance in place from the Execution Date through the Closing Date or earlier termination of this Agreement. 6.9 LITIGATION. Seller shall not allow to be commenced on its behalf any action, suit or proceeding with respect to all or any portion of the Property without Buyer's prior written consent (which consent may be withheld in Buyer's sole and absolute discretion). In the (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 14 102 WITMER ROAD, HORSHAM, PA event Seller receives any notice of any proceeding of the character described in Sections 4.14 or 4.17 which has not been previously disclosed to Buyer prior to the Closing, Seller shall promptly advise Buyer in writing. 6.10 TECHNICAL INFORMATION. Seller shall maintain the Technical Information in the form and content that Seller has maintained the Technical Information in the ordinary course of Seller's business. 6A COVENANTS OF BUYER. 6A.1 AUXILIUM LEASE. In addition to the covenants and agreements of Buyer set forth elsewhere in this Agreement, Buyer covenants and agrees that (a) Seller shall have the right to occupy and use portions of the Property after Closing pursuant to the terms and conditions of the Consent, and (b) Seller's right to occupy and use the Property shall survive any termination of the Auxilium Lease pursuant to the terms and conditions of the Consent. 6A.2 TECHNICAL INFORMATION. Buyer agrees that the Technical Information will be retained at the Property and that Seller, at its sole cost and expense, may, through February 28, 2007 and subject to the terms and conditions of the Consent, make copies of any or all of the Technical Information. 7 CONDITIONS PRECEDENT TO CLOSING. 7.1 BUYER'S CONDITIONS. The obligation of Buyer to render performance under this Agreement is subject to the following conditions precedent (and conditions concurrent, with respect to deliveries to be made by the parties at Closing) ("BUYER'S CONDITIONS"), which conditions may be waived, or the time for satisfaction thereof extended, by Buyer only in a writing executed by Buyer: 7.1.1 TITLE. Title Company shall be prepared and irrevocably committed to issue to Buyer an American Land Title Association extended coverage owner's policy of title insurance (Form B)-1970 (expressly deleting any creditor's rights exclusion) in favor of Buyer in an amount equal to the Purchase Price showing indefeasible fee simple title to the Property vested in Buyer, with those endorsements and reinsurance reasonably requested by Buyer, subject only to the Permitted Exceptions (collectively, the "OWNER'S TITLE POLICY"). 7.1.2 SELLER'S DUE PERFORMANCE. All of the representations and warranties of Seller set forth in Section 4 shall be true and correct as of the Closing Date, and Seller, on or prior to the Closing Date, shall have complied with and/or performed all of the obligations, covenants and agreements required on the part of Seller to be complied with or performed pursuant to the terms of this Agreement, including, (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 15 102 WITMER ROAD, HORSHAM, PA without limitation, the deliveries required to be made by Seller pursuant to Sections 9.1 and 9.3 hereof. 7.1.3 CONDITION OF PROPERTY. Subject to the provisions of Section 12 below, the condition of the Property shall be substantially the same on the Closing Date as on the Execution Date, except for reasonable wear and tear, any damages due to any act of Buyer or Buyer's representatives and except for changes and alterations performed in accordance with the Consent. 7.1.4 BANKRUPTCY. No action or proceeding shall have been commenced by or against Seller under the federal bankruptcy code or any state law for the relief of debtors or for the enforcement of the rights of creditors and no attachment, execution, lien or levy shall have attached to or been issued with respect to the Property or any portion thereof. 7.1.5 CC&RS ESTOPPEL. Prior to three (3) Business Days before the Closing Date, Buyer shall have received and approved a fully executed original of the CC&Rs Estoppel. 7.1.6 AUXILIUM LEASE. Auxilium shall not be in default of any of its obligations under the Auxilium Lease and the Auxilium Lease shall be in full force and effect other than due to the acts or omissions of Buyer. 7.2 SELLER'S CONDITIONS. The obligation of Seller to render performance under this Agreement is subject to the following conditions precedent (and conditions concurrent with respect to deliveries to be made by the parties at Closing) ("SELLER'S CONDITIONS"), which conditions may be waived, or the time for satisfaction thereof extended, by Seller only in a writing executed by Seller: 7.2.1 BUYER'S DUE PERFORMANCE. All of the representations and warranties of Buyer set forth in Section 5 hereof shall be true and correct as of the Closing Date, and Buyer, on or prior to the Closing Date, shall have complied with and/or performed all of the obligations, covenants and agreements required on the part of Buyer to be complied with or performed pursuant to the terms of this Agreement. 7.2.2 AUXILIUM LEASE. Buyer shall not be in default of any of its obligations under the Auxilium Lease beyond any applicable notice and cure period. 7.3 FAILURE OF CONDITION PRECEDENT. If any condition precedent to Closing has not been satisfied on or before the Closing Date, then the party whose conditions to Closing have not been satisfied (the "UNSATISFIED PARTY") shall give prompt notice to the other party of the condition or conditions that the Unsatisfied Party asserts are not satisfied. The party whose condition precedent was not satisfied may either waive the unsatisfied condition or conditions by prompt notice to the other party or terminate this Agreement, whereupon neither party shall have any further rights or obligations hereunder (other than any (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 16 102 WITMER ROAD, HORSHAM, PA obligations of either party that expressly survive termination) and the Deposit shall be immediately returned to Buyer, except if such failure of a condition is due to a default or breach by one of the parties of its representations or warranties under this Agreement or of any of its obligations hereunder, in which event the non-defaulting party shall have those rights and remedies set forth in Article 13 (Default). If the transaction contemplated by this Agreement closes, the parties shall be deemed to have waived any and all unmet or unsatisfied conditions, other than any unmet or unsatisfied conditions arising out of a breach by either party of any of its representations and warranties hereunder of which the other party has no knowledge as of Closing. 8 CLOSING. 8.1 CLOSING DATE. Subject to the provisions of this Agreement, the closing (the "CLOSING") shall take place on Tuesday, September 5, 2006, or on such earlier date as the parties hereto may agree (the "CLOSING DATE"). 8.2 CLOSING COSTS. Each party shall pay its own costs and expenses arising in connection with the Closing (including, without limitation, its own attorneys' and advisors' fees), except the following costs (the "CLOSING COSTS"), which shall be allocated between the parties as follows: 8.2.1 Seller shall pay 1/2 of the following: (a) all documentary transfer, stamp, sales and other taxes related to the transfer of the Property, (b) Escrow Agent's escrow fees and costs, and (c) all recording fees related to the transfer of ownership of the Property. 8.2.2 Buyer shall pay 1/2 of the following: (a) all documentary transfer, stamp, sales and other taxes related to the transfer of the Property, (b) Escrow Agent's escrow fees and costs, and (c) all recording fees related to the transfer of ownership of the Property. Buyer shall pay all recording fees related to all premiums, costs and fees related to the delivery of the Owner's Title Policy, the cost of the Survey, and the cost of the UCC Search. 9 CLOSING DELIVERIES. 9.1 DELIVERIES BY SELLER TO ESCROW. Not less than 1 Business Day prior to the Closing Date, Seller, at its sole cost and expense, shall deliver or cause to be delivered into Escrow the following documents and instruments, each effective as of the Closing Date and executed by Seller, in addition to the other items and payments required by this Agreement to be delivered by Seller: 9.1.1 DEED. The original executed and acknowledged Deed conveying the Property to Buyer or its nominee; (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 17 102 WITMER ROAD, HORSHAM, PA 9.1.2 NON-FOREIGN AFFIDAVIT. 2 originals of the Non-Foreign Affidavit in the form of Exhibit H attached hereto, each executed by Seller; 9.1.3 BILL OF SALE AND ASSIGNMENT. 2 original counterparts of the Bill of Sale and Assignment in the form of Exhibit I attached hereto, each executed by Seller, pursuant to which Seller shall transfer to Buyer all the Personal Property and the Intangible Property, including, without limitation, the Property Documents, in each case free and clear of all liens, mortgages, pledges, security interests, prior assignments, encumbrances and claims of any nature other than the Permitted Exceptions; 9.1.4 SELLER'S CERTIFICATE. 2 originals of a certificate, in the form of Exhibit G attached hereto (the "SELLER'S CERTIFICATE"), each executed by Seller; 9.1.5 PROOF OF AUTHORITY. Such proof of Seller's authority and authorization to enter into this Agreement and the transaction contemplated hereby, and such proof of the power and authority of the individual(s) executing or delivering any instruments, documents or certificates on behalf of Seller to act for and bind Seller as may be reasonably required by Title Company or Buyer; and 9.1.6 OTHER. Such other documents and instruments, signed and properly acknowledged by Seller, if appropriate, as may be reasonably required by Buyer, Escrow Agent, Title Company, or otherwise in order to effectuate the provisions of this Agreement and the Closing of the transactions contemplated herein (including the issuance of the Owner's Title Policy by the Title Company), including, without limitation, reasonable or customary title affidavits and so-called "gap indemnity" and related agreements. 9.2 DELIVERIES BY BUYER. On or before the Closing, Buyer, at its sole cost and expense, shall deliver or cause to be delivered into Escrow the following: 9.2.1 BALANCE, PRORATIONS & CLOSING COSTS. The balance of the Purchase Price pursuant to Section 2 hereof and Buyer's share of prorations and Closing Costs (as hereinafter defined), as provided in Sections 10 and 8.2, respectively; 9.2.2 OTHER. Such other documents and instruments, signed and properly acknowledged by Buyer, if appropriate, as may reasonably be required by Escrow Agent or otherwise in order to effectuate the provisions of this Agreement and the closing of the transactions contemplated herein. 9.3 DELIVERIES OUTSIDE OF ESCROW. Seller shall deliver possession of the Property to Buyer upon the Closing, free and clear of all tenancies and rights of third parties to occupy or possess all or any part of the Premises. Further, Seller hereby covenants and agrees, at its sole cost and expense, to deliver or cause to be delivered to deliver to Buyer, on or prior to the Closing, the following items: (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 18 102 WITMER ROAD, HORSHAM, PA 9.3.1 INTANGIBLE PROPERTY. The original of each document evidencing the Intangible Property or rights to ownership and use thereof including the Approvals if and to the extent in the possession of Seller (but if originals are not in Seller's possession, Seller shall deliver true and complete copies of such documents to the extent such copies exist and are in Seller's possession); 9.3.2 PERSONAL PROPERTY. The Personal Property, including, without limitation, all keys, pass cards, remote controls, security codes, computer software and other devices relating to access to the Improvements; provided, however, that Seller shall (a) maintain copies of same as may be required to effectuate the transactions contemplated by the Consent, and (b) deliver the Technical Information to Buyer at the Property; and 9.3.3 OTHER. Keys, combinations or card keys to all locks and security systems, and such other documents and instruments, as may be reasonably required by Buyer or otherwise in order to effectuate the provisions of this Agreement and the Closing of the transactions contemplated herein. 10 PRORATIONS. 10.1 PRORATIONS. 10.1.1 INCOME. Rentals, revenues, and other income, if any, from the Property, shall be prorated between Buyer and Seller as of the Closing Date to the extent actually collected. 10.1.2 INTENTIONALLY OMITTED. 10.1.3 EXPENSES. Taxes, assessments, improvement bonds, service or other contract fees, utility costs, and other expenses affecting the Property shall be prorated between Buyer and Seller as of the Closing Date to the extent due and payable for any period prior to the Closing. All non-delinquent real estate taxes or assessments on the Property shall be prorated based on the actual current tax bill, but if such tax bill has not yet been received by Seller by the Closing Date or if supplemental taxes are assessed after the Closing for the period prior to the Closing, the parties shall make any necessary adjustment after the Closing by cash payment to the party entitled thereto so that Seller shall have borne all taxes, including all supplemental taxes, allocable to the period prior to the Closing and Buyer shall bear all taxes, including all supplemental taxes, allocable to the period from and after the Closing. 10.1.4 ADJUSTMENTS. If any expenses attributable to the Property and allocable to the period prior to the Closing are discovered or billed after the Closing, the parties shall make any necessary adjustment after the Closing by cash payment to the party entitled thereto so that Seller shall have borne all expenses allocable to the (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 19 102 WITMER ROAD, HORSHAM, PA period prior to the Closing and Buyer shall bear all expenses allocable to the period from and after the Closing. 10.1.5 TAX APPEALS. With respect to any property tax appeals or reassessments filed by Seller for tax years prior to the year in which the Closing occurs, Seller shall be entitled to the full amount of any refund or rebate resulting therefrom, and with respect to any property tax appeals or reassessments filed by Seller or Buyer for the tax year in which the Closing occurs, Seller and Buyer shall share the amount of any rebate or refund resulting therefrom (after first paying to Seller or Buyer, as applicable, all costs and expenses incurred by Seller in pursuing such appeal or reassessment) in proportion to their respective periods of ownership of the Property for such tax year; 10.1.6 GENERALLY. For purposes of calculating prorations, Buyer shall be deemed to be in title to the Property, and therefore entitled to the income and responsible for the expenses, after 12:01 a.m. Eastern Daylight Saving Time. All such prorations shall be made on the basis of the actual number of days of the month which shall have elapsed as of the day of the Closing and based upon the actual number of days in the month and a three hundred sixty-five (365) day year. The provisions of this Section 10 shall survive the Closing for a period of 1 year. 10.1.7 PARKING LOT RESTRIPING CREDIT. At Closing, Buyer shall receive a credit against the Purchase Price in the amount of $7,200 in connection with the restriping of the parking lot located on the Land. 10.2 PRELIMINARY CLOSING STATEMENT. 10 days prior to the Closing, Escrow Agent shall deliver to each of the parties for their review and approval a preliminary closing statement (the "PRELIMINARY CLOSING STATEMENT") based on an income expense statement prepared by Seller, approved by Buyer, and delivered to Escrow Agent prior to said date, setting forth (i) the proration amounts allocable to each of the parties pursuant to this Section 10 and (ii) the Closing Costs allocable to each of the parties pursuant to Section 8.2 hereof. Based on each of the party's comments, if any, regarding the Preliminary Closing Statement, Escrow Agent shall revise the Preliminary Closing Statement and deliver a final, signed version of a closing statement to each of the parties at the Closing (the "CLOSING STATEMENT"). 11 ESCROW. 11.1 OPENING OF ESCROW. Promptly following the Execution Date, Buyer and Seller shall each cause a purchase and sale escrow ("ESCROW") to be opened with Escrow Agent by delivery to Escrow Agent of 2 duplicate partially executed originals of this Agreement executed by Seller and Buyer. Upon receipt of such partially executed originals of this Agreement, Escrow Agent shall form 2 duplicate original counterparts of this Agreement and telephonically confirm to Buyer and Seller the date upon which Escrow is opened (the "OPENING OF ESCROW"). On or immediately after the Opening of Escrow, Escrow (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 20 102 WITMER ROAD, HORSHAM, PA Agent shall (a) confirm the same by executing and dating the 3 duplicate original counterparts of this Agreement in the space provided for Escrow Agent, and (b) deliver a fully executed original of this Agreement to each of Seller and Buyer. 11.2 ESCROW INSTRUCTIONS. This Agreement shall constitute escrow instructions to Escrow Agent as well as the agreement of the parties. Escrow Agent is hereby appointed and designated to act as Escrow Agent and instructed to deliver, pursuant to the terms of this Agreement, the documents and funds to be deposited into Escrow as herein provided. The parties hereto shall execute such additional escrow instructions, not inconsistent with this Agreement as determined by counsel for Buyer and Seller, as Escrow Agent shall deem reasonably necessary for its protection, if any (as may be modified by and mutually acceptable to Buyer, Seller and Escrow Agent). In the event of any inconsistency between this Agreement and such additional escrow instructions, the provisions of this Agreement shall govern. 11.3 ACTIONS BY ESCROW AGENT. Provided that Escrow Agent shall not have received written notice from Buyer or Seller of the failure of any condition to the Closing or of the termination of the Escrow and this Agreement, when Buyer and Seller have deposited into Escrow the documents and funds required by this Agreement, and Title Company is unconditionally and irrevocably committed to issue the Owner's Title Policy concurrently with the Closing, Escrow Agent shall, in the order and manner herein below indicated, take the following actions: 11.3.1 FUNDS. Following Title Company's acknowledgment that it is prepared and irrevocably committed to issue the Owner's Title Policy to Buyer, disburse all funds deposited with it by Buyer as follows: (a) Pursuant to the Closing Statement, retain for Escrow Agent's own account all escrow fees and costs, disburse to Title Company the fees and expenses incurred in connection with the issuance of the Owner's Title Policy, and disburse to any other persons or entities entitled thereto the amount of any other Closing Costs; (b) Disburse to Seller an amount equal to the Purchase Price, less or plus the net debit or credit to Seller by reason of the prorations and allocation of Closing Costs provided for in Sections 10 and 8.2. Seller's portion (as provided in Section 8.2) of the escrow fees, title fees and other Closing Costs shall be paid pursuant to clause (a) above; and (c) Disburse to Buyer any remaining funds in the possession of Escrow Agent after payments pursuant to clauses (a) and (b) above have been completed. 11.3.2 RECORDING. Cause the Deed and any other documents which the parties hereto may mutually direct to be recorded in the Recorder of Deeds Office of (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 21 102 WITMER ROAD, HORSHAM, PA Montgomery County, Pennsylvania and obtain conformed copies thereof for distribution to Buyer and Seller. 11.3.3 OWNER'S TITLE POLICY. Cause Title Company to issue the Owner's Title Policy to Buyer. 11.3.4 DELIVERY OF DOCUMENTS. Deliver to Buyer and Seller one original of each of all documents deposited into Escrow, other than the Deed and any other recorded documents. 11.4 CONFLICTING DEMANDS. Upon receipt of a written demand for the Deposit (a "DEPOSIT DEMAND") by Seller or Buyer (the "DEMANDING PARTY"), Escrow Agent shall promptly send a copy of such Deposit Demand to the other party (the "NON-DEMANDING PARTY"). Except in connection with the timely delivery of a Due Diligence Termination Notice (in which event the Deposit shall be immediately returned to Buyer), Escrow Agent shall hold the Deposit for 5 Business Days from the date of delivery by Escrow Agent of the Deposit Demand to the non-demanding party ("OBJECTION PERIOD") or until Escrow Agent receives a confirming instruction from the non-demanding party. In the event the non-demanding party delivers to Escrow Agent written objection to the release of the Deposit to the demanding party (an "OBJECTION NOTICE") within the Objection Period (which Objection Notice shall set forth the basis under this Agreement for objecting to the release of the Deposit), Escrow Agent shall promptly send a copy of the Objection Notice to the demanding party. In the event of any dispute between the parties regarding the release of the Deposit, Escrow Agent, in its good faith business judgment, may disregard all inconsistent instructions received from either party and may either (a) hold the Deposit until the dispute is mutually resolved and Escrow Agent is advised of such mutual resolution in writing by both Seller and Buyer, or Escrow Agent is otherwise instructed by a final non-appealable judgment of a court of competent jurisdiction, or (b) deposit the Deposit with a court of competent jurisdiction by an action of interpleader (whereupon Escrow Agent shall be released and relieved of any further liability or obligations hereunder from and after the date of such deposit). In the event Escrow Agent shall in good faith be uncertain as to its duties or obligations hereunder or shall receive conflicting instructions, claims or demands from the parties hereto (expressly excluding however a conflicting demand given by Seller after Buyer has delivered a Due Diligence Termination Notice and demand for the Deposit), Escrow Agent shall promptly notify both parties in writing and thereafter Escrow Agent shall be entitled (but not obligated) to refrain from taking any action other than to keep safely the Deposit until Escrow Agent shall receive a joint instruction from both parties clarifying Escrow Agent's uncertainty or resolving such conflicting instructions, claims or demands, or until a final non-appealable judgment of a court of competent jurisdiction instructs Escrow Agent to act. 11.5 REAL ESTATE REPORTING PERSON. Escrow Agent is designated the "real estate reporting person" for purposes of section 6045 of title 26 of the United States Code and Treasury (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 22 102 WITMER ROAD, HORSHAM, PA Regulation 1.6045-4 and any instructions or settlement statement prepared by Escrow Agent shall so provide. Upon the consummation of the transaction contemplated by this Agreement, Escrow Agent shall file Form 1099 information return and send the statement to Seller as required under the aforementioned statute and regulation. 11.6 DESTRUCTION OF DOCUMENTS; SURVIVAL. Escrow Agent is hereby authorized to destroy or otherwise dispose of any and all documents, papers, instructions and other material concerning the Escrow at the expiration of 6 years from the later of (a) the Closing, (b) the final disbursement of any funds maintained in Escrow after the Closing, or (c) the final release of the Deposit following the termination of this Agreement. The provisions of this Section 11 shall survive the Closing or earlier termination of this Agreement until Escrow Agent's duties and obligations hereunder are fully and finally discharged. 12 RISK OF LOSS. 12.1 CONDEMNATION. If, prior to the Closing Date, all or any portion of the Property is taken by condemnation or eminent domain (or is the subject of a pending or contemplated taking which has not been consummated), Seller shall immediately notify Buyer of such fact. In such event, Buyer shall have the option to terminate this Agreement by delivering written notice to Seller not later than 30 days after delivery of such notice from Seller. Upon such termination, Escrow Agent shall immediately return the Deposit to Buyer and neither party shall have any further rights or obligations hereunder, other than pursuant to any provision hereof which expressly survives the termination of this Agreement. If Buyer does not elect to terminate this Agreement, Seller shall not compromise, settle or adjust any award without Buyer's prior written consent (which consent may be withheld in Buyer's sole and absolute discretion). At the Closing, Seller shall assign and turn over to Buyer, and Buyer shall be entitled to receive and keep all awards for such taking or pending or contemplated taking. 12.2 CASUALTY. 12.2.1 MAINTAIN INSURANCE. Seller shall maintain in effect until the Closing Date the insurance policies (or like policies) now in effect with respect to the Property. 12.2.2 MINIMAL DAMAGE. If prior to the Closing Date any portion of the Property is damaged or destroyed by fire or other casualty, and the cost of repair or restoration thereof shall be $1,000,000 or less (as established by good faith estimate obtained by Seller), this Agreement shall remain in force. 12.2.3 SUBSTANTIAL DAMAGE. If prior to the Closing Date any portion of the Property is damaged or destroyed by fire or other casualty, and the cost of repair or restoration thereof shall be more than $1,000,000 (as established by good faith estimates obtained by Seller), or such fire or casualty allows Auxilium to terminate the Auxilium Lease, Buyer may within fifteen (15) days after receipt of notice ("DAMAGE NOTICE") of said damage or destruction, terminate this (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 23 102 WITMER ROAD, HORSHAM, PA Agreement by giving written notice thereof to Seller, and if this Agreement is so terminated, then the Deposit shall be immediately refunded to Buyer, and thereafter neither party shall have any further liability hereunder. If Buyer does not elect to terminate this Agreement as provided herein, this Agreement shall remain in full force and effect, and the provisions of Section 12.2.4 (Closing After Minimal or Substantial Damage) shall apply. 12.2.4 CLOSING AFTER MINIMAL OR SUBSTANTIAL DAMAGE. So long as this Agreement shall remain in force under Section 12.2.2 (Minimal Damage) or 12.2.3 (Substantial Damage), then all proceeds of insurance collected prior to Closing, plus the amount of deductible under Seller's insurance policy, shall be credited to Buyer against the Purchase Price payable by Buyer at Closing, and all unpaid claims and rights in connection with losses shall be assigned to Buyer at Closing and the parties shall proceed to Closing without any adjustment in the Purchase Price. 13 DEFAULT. 13.1 DEFAULT BY BUYER. Buyer recognizes that if the purchase and sale contemplated by this Agreement is not consummated because of Buyer's default and Seller is otherwise ready, willing, able to perform its obligations under this Agreement, Seller shall be entitled to compensation for such detriment. Seller and Buyer acknowledge that it is extremely difficult and impracticable to ascertain the extent of the detriment, and to avoid this problem, Seller and Buyer agree that if the purchase and sale contemplated by this Agreement is not consummated because of Buyer's default under this Agreement, which default is not cured within 5 days after the date of receipt of a notice from Seller identifying the default, then Seller shall be entitled to retain the Deposit as liquidated damages and as Seller's sole and exclusive remedy. The parties agree that the sum stated above as liquidated damages shall be in lieu of all other relief to which Seller might otherwise be entitled, Seller hereby specifically waiving any and all rights that it may have to damages or specific performance as a result of Buyer's default under this Agreement. 13.2 DEFAULT BY SELLER. In the event that any of Seller's representations, warranties or covenants contained in this Agreement are untrue or if Seller shall have failed to have performed any of the covenants and/or agreements contained in this Agreement that are to be performed by Seller, on or before the date set forth in this Agreement for the performance thereof and Buyer is otherwise ready, willing, able to perform its obligations under this Agreement, which default is not cured within 5 days after the date of receipt of a notice from Buyer identifying the default, Buyer may, at its option, rescind this Agreement by giving written notice of such rescission to Seller and Seller shall cause the Escrow Agent to immediately thereafter return the Deposit to Buyer, Seller shall reimburse Buyer for all of Buyer's out-of-pocket costs and expenses in an aggregate amount not to exceed $100,000 incurred in connection with the transaction contemplated (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 24 102 WITMER ROAD, HORSHAM, PA by this Agreement (including, but not limited to, costs incurred to negotiate the Auxilium Lease), and thereupon the parties shall have no further liability to each other hereunder. In the alternative, Buyer may seek to enforce specific performance of this Agreement. As a condition precedent to Buyer exercising any right it may have to specific performance of this Agreement, Buyer must commence such an action enforcing such right within ninety (90) days after the originally scheduled Closing Date (but Buyer shall have no obligation to maintain its Closing funds on deposit with the Escrow Agent). Buyer agrees that its failure to timely commence such an action for specific performance within such ninety (90) day period shall be deemed a waiver by it of its right to commence an action for specific performance as well as a waiver by it of any right it may have to file or record a notice of lis pendens or notice of pendency of action or similar notice against any portion of the Property within such ninety (90) day period. If Seller takes any action intended, designed, or calculated to make the remedy of specific performance unavailable to Buyer or frustrate, hinder, or delay Buyer's efforts to obtain specific performance or render such remedy meaningless or of little or no value to Buyer other than Seller's defense of any such action commenced by Buyer in a court of law, Seller shall pay to Buyer an amount equal to all damages sustained by Buyer as a result of such action. 14 BROKERS. Seller and Buyer each hereby represent, warrant to and covenant to each other that it has not dealt with any third party other than Trammell Crow Company ("BROKER") in a manner which would obligate the other to pay any brokerage commission, finder's fee or other compensation due or payable with respect to the transaction contemplated hereby other than a commission to be paid to Broker pursuant to a separate agreement, which shall be paid by Seller only upon the Closing of the purchase and sale contemplated hereby. Seller hereby indemnifies and agrees to protect, defend and hold Buyer harmless from and against any and all claims, losses, damages, costs and expenses (including attorneys' fees, charges and disbursements) incurred by Buyer by reason of any breach or inaccuracy of the representation, warranty and agreement of Seller contained in this Section 14. Buyer hereby indemnifies and agrees to protect, defend and hold Seller harmless from and against any and all claims, losses, damages, costs and expenses (including attorneys' fees, charges and disbursements) incurred by Seller by reason of any breach or inaccuracy of the representation, warranty and agreement of Buyer contained in this Section 14. The provisions of this Section 14 shall survive the Closing or earlier termination of this Agreement. 15 CONFIDENTIALITY. 15.1 BUYER. All "CONFIDENTIAL INFORMATION" (defined below) that Seller, its representatives, consultants, counsel, directors, officers, employees, and agents (each, a "REPRESENTATIVE," and collectively, the "REPRESENTATIVES") furnishes to any of Buyer and its Representatives (including, but not limited to, any such information furnished before the date of this Agreement) shall be used solely in connection with the transaction contemplated by this Agreement ("STATED PURPOSE") and not for any other purpose. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 25 102 WITMER ROAD, HORSHAM, PA Buyer shall ensure that all Confidential Information is kept confidential, provided that such information may be disclosed by Buyer to those Representatives of Buyer who have a need to know such information in connection with the Stated Purpose, are informed by Buyer of the confidential nature of such information and of the confidentiality undertakings of Buyer contained herein, and are bound to Buyer by a like obligation of confidentiality and restriction on use. Buyer shall be responsible for any breach of this Agreement by its Representatives. 15.1.1 For purposes of this Section 15.1, "CONFIDENTIAL INFORMATION" means any of Seller's proprietary or confidential information, technical data, trade secrets, or know-how, including, but not limited to, research, product plans, products, service plans, services, customer lists and customers, markets, software, developments, inventions, processes, formulas, technology, processes, designs, drawings, engineering, marketing, distribution and sales methods and systems, sales and profit figures, finances and other related business information disclosed to Buyer by or on behalf of Seller, either directly or indirectly, in writing, orally or by drawings or inspection of documents or other tangible property. However, Confidential Information does not include any of the foregoing items that: (a) is now, or in the future becomes, public knowledge other than through the acts or omissions of Buyer; (b) is required to be disclosed pursuant to applicable Laws; provided, however, that Buyer shall promptly advise Seller of its notice of any such Laws; (c) Buyer can demonstrate by written records was previously known by it; (d) is received by Buyer from another person or entity who is under no obligation of confidentiality to Seller to keep the same confidential; or (e) relate solely to the Property and/or the condition thereof that is disclosed to Auxilium as part of Auxilium's due diligence of the Property in connection with the negotiation and execution of the Auxilium Lease. Nothing in this Agreement shall prohibit, limit, restrict, or qualify Buyer's right to publicize in any medium the purchase and sale of the Property. 15.1.2 Neither Buyer nor its Representatives shall, without Seller's prior written consent, disclose to any person or entity (other than the persons employed by Buyer and its Representatives who are actively and directly participating in the Stated Purpose) any information about Buyer's discussions regarding the Stated Purpose or the terms, conditions, or other facts relating thereto, including the fact that discussions are taking place with respect thereto or the status thereof, or the fact that the Confidential Information has been made available to Buyer, except to the extent that such disclosure is required by applicable Laws; provided, however, that (a) Buyer shall promptly advise Seller of its notice of any such Laws, and (b) from and after the Closing Date, Buyer shall have the right in connection with its ownership, management, operation, and leasing activities to disclose to others without notice to Seller and without Seller's consent that portion of the Confidential Information, if any, relating to the Real Property, the Personal Property, and the Intangible Property. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 26 102 WITMER ROAD, HORSHAM, PA 15.1.3 If Closing does not occur under this Agreement, Buyer shall promptly deliver to Seller all Confidential Information, in whatever medium, including any and all copies thereof, and shall cause all summaries or synopses thereof to be destroyed. Upon receipt of a written request from Seller, such destruction shall be confirmed in writing by Buyer to Seller. The provisions of this Agreement shall survive the termination of this Agreement, such return of Confidential Information, and such destruction of summaries and synopses thereof. 15.1.4 Except as otherwise provided in this Agreement, Buyer understands and acknowledges that neither Seller nor any of its Representatives is making any representation or warranty as to the accuracy or completeness of any Confidential Information. Neither Seller, its affiliates nor any of its respective officers, directors, employees, agents, or controlling persons within the meaning of Section 20 of the Securities Exchange Act of 1934, shall have any liability to Buyer or any of its Representatives relating to or arising from the use of the Confidential Information. 15.1.5 Buyer hereby acknowledges that it is aware (and, if applicable, that its Representatives who are apprised of this matter have been advised) that the United States securities laws prohibit any person who has material non-public information about a company from purchasing or selling securities of such company, or from communicating such information to any other person under circumstances in which it is reasonably foreseeable that such person is likely to purchase or sell such securities. 15.1.6 Neither the execution of this Agreement nor the furnishing of any Confidential Information hereunder shall be construed as granting, either expressly or by implication, estoppel or otherwise, any license under or title to any invention or patent now or hereafter owned or controlled by Seller. 15.1.7 Buyer agrees that it would be impossible or inadequate to measure and calculate Seller's damages from any breach of the covenants set forth in this Section 15.1. Accordingly, Buyer agrees that if it breaches any of such covenants, Seller will have available, in addition to any other right or remedy available, the right to seek an injunction from a court of competent jurisdiction restraining such breach or threatened breach and to specific performance of any such provision of this Section 15.1. Buyer further agrees that no bond or other security shall be required in obtaining such equitable relief and each party hereby consents to the issuance of such injunction and to the ordering of specific performance. 15.2 SELLER. Seller agrees that both prior to and after the Closing, except as otherwise provided herein (including the Estoppel Certificates) or required by law, and except for the exercise by Seller of any remedy hereunder, Seller shall (a) keep confidential the pendency of this transaction with Buyer, the terms and conditions contained in the (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 27 102 WITMER ROAD, HORSHAM, PA Agreement and the identity of Buyer and the relationship between Buyer and the entity to which Buyer may assign this Agreement or which Buyer designates as the party to whom Seller shall convey the Property at the Closing, and (b) disclose such information only to Seller's agents, employees, contractors, consultants or attorneys, as well as Tenants and title company personnel, with a need to know such information in connection with effecting this transaction, provided that Seller shall inform all such persons receiving such confidential information from Seller of the confidentiality requirement and (to the extent within Seller's control) cause such confidence to be maintained. Disclosure of the pendency of this transaction by Seller shall not be prohibited if that disclosure is of information that is or becomes a matter of public record or public knowledge as a result of the Closing of this transaction or from sources other than Seller or its agents, employees, contractors, consultants or attorneys. 15.3 JUNE 8, 2006 CONFIDENTIALITY AGREEMENT. The provisions of this Section 15 supersede, replace, and terminate the Confidentiality Agreement dated June 8, 2006 between Seller and Buyer. 16 INTENTIONALLY DELETED. 17 MISCELLANEOUS PROVISIONS. 17.1 GOVERNING LAW. This Agreement and the legal relations between the parties hereto shall be governed by and construed and enforced in accordance with the laws of the Commonwealth of Pennsylvania, without regard to its principles of conflicts of law. 17.2 ENTIRE AGREEMENT. This Agreement, including the exhibits and schedules attached hereto, constitutes the entire agreement between Buyer and Seller pertaining to the subject matter hereof and supersedes all prior agreements, understandings, letters of intent, negotiations and discussions, whether oral or written, of the parties, and there are no warranties, representations or other agreements, express or implied, made to either party by the other party in connection with the subject matter hereof except as specifically set forth herein or in the documents delivered pursuant hereto or in connection herewith. Without limiting the foregoing, upon the Execution Date, that certain Letter of Intent dated as of July 12, 2006, between Buyer and Seller, shall terminate and be of no further force or effect. 17.3 MODIFICATIONS; WAIVER. No supplement, modification, waiver or termination of this Agreement shall be binding unless executed in writing by the party to be bound thereby. No waiver of any provision of this Agreement shall be deemed or shall constitute a waiver of any other provision hereof (whether or not similar), nor shall such waiver constitute a continuing waiver unless otherwise expressly provided. 17.4 NOTICES. All notices, consents, requests, reports, demands or other communications hereunder (collectively, "NOTICES") shall be in writing and may be given personally, by reputable overnight delivery service or by facsimile transmission (with in the case of a (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 28 102 WITMER ROAD, HORSHAM, PA facsimile transmission, confirmation by reputable overnight delivery service) to each of the parties at the following addresses: To Buyer: ARE-PA Region No. 6, LLC c/o Alexandria Real Estate Equities, Inc. 385 E. Colorado Blvd., Suite 299 Pasadena, California 91101 Attention: Corporate Secretary Re: 102 Witmer Road Telephone: (626) 578-0777 Facsimile: (626) 578-0770 With A Copy To: Kevin L. Shepherd, Esquire Venable LLP Suite 1800, Two Hopkins Plaza Baltimore, Maryland 21201-2978 Telephone: (410) 244-7772 Facsimile: (410) 244-7742 To Seller: Neose Technologies, Inc. Attention: Mr. A. Brian Davis Senior Vice President and Chief Financial Officer Neose Technologies, Inc. 102 Witmer Road Horsham. Pennsylvania 19044 Telephone: (215) 315-9020 Facsimile: (215) 441-5112 With a Copy To: Matthew J. Swett, Esquire Pepper Hamilton LLP 3000 Two Logan Square Eighteenth and Arch Streets Philadelphia, Pennsylvania 19103 Telephone: (215) 981-4788 Facsimile: (215) 689-4539 To Escrow Agent: Chicago Title Insurance Company Attention: Ms. Amy D. Hiraheta Assistant Vice President, Senior National Title Coordinator 700 South Flower Street, Suite 800 Los Angeles, California 90017 Telephone: (213) 488-4373 Facsimile: (213) 488-4380 (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 29 102 WITMER ROAD, HORSHAM, PA or to such other address or such other person as the addressee party shall have last designated by written notice to the other party. Notices given by facsimile transmission shall be deemed to be delivered as of the date and time when transmission and receipt of such facsimile is when confirmed; and all other Notices shall have been deemed to have been delivered on the date of delivery or refusal. 17.5 EXPENSES. Subject to the allocation of Closing Costs provided in Section 8.2 hereof, whether or not the transactions contemplated by this Agreement shall be consummated, all fees and expenses incurred by any party hereto in connection with this Agreement shall be borne by such party. 17.6 ASSIGNMENT. 17.6.1 SELLER'S RIGHT TO ASSIGN. Seller shall not have the right, power, or authority to assign, pledge or mortgage this Agreement or any portion of this Agreement, or to delegate any duties or obligations arising under this Agreement, voluntarily, involuntarily, or by operation of law. 17.6.2 BUYER'S RIGHT TO ASSIGN. Upon delivery of written notice to Seller and Escrow Agent, Buyer shall have the right, power, and authority to assign this Agreement or to delegate any duties or obligations arising under this Agreement, voluntarily, involuntarily or by operation of law, to any affiliate of Buyer. Upon such assignment, Buyer shall be relieved of all obligations under this Agreement and the Escrow. 17.7 SEVERABILITY. Any provision or part of this Agreement which is invalid or unenforceable in any situation in any jurisdiction shall, as to such situation and such jurisdiction, be ineffective only to the extent of such invalidity and shall not affect the enforceability of the remaining provisions hereof or the validity or enforceability of any such provision in any other situation or in any other jurisdiction. 17.8 SUCCESSORS AND ASSIGNS; THIRD PARTIES. Subject to and without waiver of the provisions of Section 17.6 hereof, all of the rights, duties, benefits, liabilities and obligations of the parties shall inure to the benefit of, and be binding upon, their respective successors and assigns. Except as specifically set forth or referred to herein, nothing herein expressed or implied is intended or shall be construed to confer upon or give to any person or entity, other than the parties hereto and their successors or assigns, any rights or remedies under or by reason of this Agreement. 17.9 COUNTERPARTS. This Agreement may be executed in as many counterparts as may be deemed necessary and convenient, and by the different parties hereto on separate counterparts, each of which, when so executed, shall be deemed an original, but all such counterparts shall constitute one and the same instrument. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 30 102 WITMER ROAD, HORSHAM, PA 17.10 HEADINGS. The section headings of this Agreement are for convenience of reference only and shall not be deemed to modify, explain, restrict, alter or affect the meaning or interpretation of any provision hereof. 17.11 TIME OF THE ESSENCE. Time shall be of the essence with respect to all matters contemplated by this Agreement. 17.12 FURTHER ASSISTANCE. In addition to the actions recited herein and contemplated to be performed, executed, and/or delivered by Seller and Buyer, Seller and Buyer agree to perform, execute and/or deliver or cause to be performed, executed and/or delivered at the Closing or after the Closing any and all such further acts, instruments, deeds and assurances as may be reasonably required to consummate the transactions contemplated hereby. 17.13 NUMBER AND GENDER. Whenever the singular number is used, and when required by the context, the same includes the plural, and the masculine gender includes the feminine and neuter genders. 17.14 CONSTRUCTION. This Agreement shall not be construed more strictly against one party hereto than against any other party hereto merely by virtue of the fact that it may have been prepared by counsel for one of the parties. 17.15 POST-CLOSING ACCESS TO RECORDS. Upon receipt by Seller of Buyer's reasonable written request at anytime and from time to time within a period of 2 years after the Closing, Seller shall make available to Buyer and its accountants and designees, for inspection and copying during normal business hours and at Buyer's sole cost and expense, (i) all accounting records relating to the Property for the calendar year period ended December 31, 2005, and for the period from January 1, 2006 through the Closing Date, including, without limitation, all general ledgers, cash receipts, canceled checks and other accounting documents or information reasonably requested by Buyer and related to the Property, and (ii) all other records related to the Property, in either case whether in the possession or control of Seller or Seller's manager, asset manager or other agent. 17.16 EXHIBITS. All exhibits attached hereto are hereby incorporated by reference as though set out in full herein. 17.17 ATTORNEYS' FEES. If any action is brought by either party against the other party, relating to or arising out of this Agreement, the transaction described herein or the enforcement hereof, the prevailing party shall be entitled to recover from the other party reasonable attorneys' fees, costs and expenses incurred in connection with the prosecution or defense of such action. For purposes of this Agreement, the term "ATTORNEYS' FEES" or "ATTORNEYS' FEES AND COSTS" shall mean the fees and expenses of counsel to the parties hereto, which may include printing, photostating, duplicating and other expenses, air freight charges, and fees billed for law clerks, paralegals and other persons not admitted to the bar but performing services under the supervision of an attorney, and the costs and (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 31 102 WITMER ROAD, HORSHAM, PA fees incurred in connection with the enforcement or collection of any judgment obtained in any such proceeding. The provisions of this Section shall survive the entry of any judgment, and shall not merge, or be deemed to have merged, into any judgment. 17.18 BUSINESS DAYS. As used herein, the term "BUSINESS DAY" shall mean a day that is not a Saturday, Sunday or legal holiday. In the event that the date for the performance of any covenant or obligation under this Agreement shall fall on a Saturday, Sunday or legal holiday under the laws of the Commonwealth of Pennsylvania or the State of California, the date for performance thereof shall be extended to the next Business Day. [REMAINDER OF PAGE INTENTIONALLY BLANK.] (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 32 102 WITMER ROAD, HORSHAM, PA IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the day and year first above written. BUYER: ARE-PA REGION NO. 6, LLC, a Delaware limited liability company By: Alexandria Real Estate Equities, L.P., a Delaware limited partnership, its managing member By: ARE-QRS CORP., a Maryland corporation, general partner Execution Date: September 1, 2006 By: /s/ Jennifer J. Pappas ------------------------------------ Its: Vice President and Assistant Secretary ----------------------------------- SELLER: NEOSE TECHNOLOGIES, INC., a Delaware corporation Execution Date: September 1, 2006 By: /s/ George J. Vergis, Ph.D. ------------------------------------ Name: George J. Vergis, Ph.D. ---------------------------------- Its: President and CEO ----------------------------------- ESCROW AGENT: The undersigned Escrow Agent accepts the foregoing Agreement of Purchase and Sale and Joint Escrow Instructions and agrees to act as Escrow Agent under this Agreement in strict accordance with its terms. CHICAGO TITLE INSURANCE COMPANY Date: September 1, 2006 By: /s/ Gus Aguilar --------------------------------- Name: Gus Aguilar ------------------------------- Its: AVP and Senior Escrow Officer -------------------------------- (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 33 102 WITMER ROAD, HORSHAM, PA EXHIBIT A LEGAL DESCRIPTION Metes and Bounds description of Unit 30, Block 60A, APN # 36-00-11954-016, lands now or formerly Neose Technologies, Inc., Horsham Township, Montgomery County, Commonwealth of Pennsylvania as described on the ALTA/ACSM Land Title Survey prepared by Control Point Associates, Inc., dated August 8, 2006, File No. CP97002.02 as follows: BEGINNING at a concrete monument along the Northeasterly legal right-of-way of Witmer Road (a.k.a. T-405, 60.00 feet wide right-of-way), at its intersection with the dividing line between Unit 30, Block 60A, APN #36-00-11954-016, Lands now or formerly Neose Technologies, Inc., and Unit 1, Block 60A, APN #36-00-11954-025, Lands now or formerly Liberty Property Limited Partnership, and from said point of beginning running, thence; 1. along the northeasterly legal right-of-way line of Witmer Road, North 23 degrees 42 minutes 10 seconds West, a distance of 376.11 feet to a point, thence; 2. along the dividing line between Unit 30, Block 60A, APN # 36-00-11954-016, and Unit 29, Block 60A, APN # 36-00-11954-007, Lands now or formerly Liberty Property Limited Partnership, North 44 degrees 49 minutes 22 seconds East, a distance of 428.99 feet to a railroad spike, thence; 3. along the dividing line between Unit 30, Block 60A, APN # 36-00-11954-016 and Unit 22, Block 60A, APN # 36-00-10235-052, Lands now or formerly Liberty Property Limited Partnership, South 45 degrees 10 minutes 38 seconds East, a distance of 350.00 feet to a concrete monument; 4. along the dividing line between Unit 30, Block 60A, APN #36-00-11954-016 and Unit 1, Block 60A, APN # 35-00-11954-025, South 44 degrees 49 minutes 22 seconds West, a distance of 566.68 feet to a concrete monument on the northeasterly legal right-of-way of Witmer Road and the point and place of beginning. Containing 174,242 square feet or 4.000 acres, more or less. TOGETHER WITH easements as set forth in Easement Agreement between Liberty Property Limited Partnership, a Pennsylvania limited partnership and Neose Technologies, Inc., a Delaware corporation, dated January 24, 2002 and recorded January 30, 2002 in the Office of the Recorder of Deeds in and for the County of Montgomery, Pennsylvania in Deed Book 5393 at Page 2346. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 34 102 WITMER ROAD, HORSHAM, PA EXHIBIT B PERSONAL PROPERTY INVENTORY (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are ALEXANDRIA, registered trademarks of Alexandria Real Estate Equities, Inc. 35 EXHIBIT B WITMER ROAD PROPERTY - INCLUDED ASSETS GROUPING LEGEND 1A GENERAL BUILDING INFRASTRUCTURE 2A PROCESS EQUIPMENT 3A LAB EQUIPMEN 6A IT EQUIPMENT
FAS SYSTEM EQUIPMENT FAS GROUP # TAG # TAG # ACQ DATE VENDOR - ----- ------ ------------ ------- ---------- -------------------------------- 1a 2,203 AE-5048 01425 5/31/2005 GE Infrastructure Sensing 1a N/A AU-1000 GETINGE 1a 1,535 BSC-1000 01005 8/11/2003 Thermo Forma 1a 1,534 BSC-1001 00630 8/11/2003 Thermo Forma 1a 1,944 BSC-1002 01258 7/31/2004 Thermo Forma 1a 1,945 BSC-1003 01322 7/31/2004 Thermo Forma 1a 1,119 BSC-2000 00695 1/31/2002 ThermoForma 1a 1,117 BSC-2700 00696 1/31/2002 ThermoForma 1a 1,116 BSC-3000 00697 1/31/2002 ThermoForma 1a 1,120 BSC-304 00694 1/31/2002 ThermoForma 1a 1,115 BSC-3700 00698 1/31/2002 ThermoForma 1a 1,521 DW-0001 00621 7/11/2003 Lancer USA Inc 1a 1,522 DW-0002 00622 7/11/2003 Lancer USA Inc 1a 530 H-0003 00962 Labconco 1a N/A H-0004 6 Foot 1a N/A H-0005 6 Foot 1a N/A H-0007 Labconco, 4 Foot 1a N/A H-0010 Labconco 1a N/A H-0011 Labconco 1a 693 H-1009 00146 2/29/2000 ThermoQuest 1a 682 ML-03 00127 1/28/2000 FTS Kinetics 1a 1,450 PK-1850 00560 1/1/2003 Techniserv 1a 1,448 PK-1910 00561 1/1/2003 Steris 1a 1,451 PK-1950 00556 1/1/2003 Techniserv 1a N/A PN-01 n/a Process Network 1a N/A RP-1720 Fristam Pump 1a N/A RP-1990 N/A Fristam Pump 1a 1,449 ST-1910 00553 1/1/2003 Steris 1a N/A Z-100 1-Tank, w/ HX & 2 Pumps 1a N/A Z-101 1-Tank, w/ HX & 2 Pumps GROUP DESCRIPTION LOCATION SERIAL NUMBER - ----- -------------------------------------------- ---------------------- -------------------- 1a Kaye Validator 2000 Trailer 504030 1a AUTOCLAVE/STERILIZER 413 #N/A 1a Bio Safe Cabinet-4 ft. Pilot Plant - Rm 361 100902-3088 1a Bio Safe Cabinet-4 ft. Pilot Plant - Rm 362 100902-3085 1a Bio Safety Cabinet-4ft PP 169A 101603-03865 1a Bio Safety Cabinet-4ft PP - Rm 358 101603-03866 1a 6ft Bio Safety Cabinet PP- Room 316 0 1a 6ft Bio Safety Cabinet Room 324 22539 1a 6ft Bio Safety Cabinet PP Room 335 0 1a 4ft Bio Safety Cabinet Room 304 22536 2070 1a 6ft Bio Safety Cabinet Room 341 22539 1a Glassware washing machine Common Area 413 3E042738 1a Glassware washing machine Common Area 413 3E042737 1a Fisher Scientific-BioHood 6 ft Purif-6 Lab 9 0 1a Biosafety Cabinet Lab 1 #N/A 1a Biosafety Cabinet Lab 1 #N/A 1a Biosafety Cabinet Lab 10 #N/A 1a BIOLOGICAL SAFETY CABINET Lab 8 010615620G 1a BIOLOGICAL SAFETY CABINET Lab 8 010615613G 1a Bio Safe Cabinet WR LAB 4 ROOM 132 23855-339 1a Lyostar, LS 00013a (lyophilizer) Rm 304 Neose # ML-003 1a CIP System utility rm PK1850 1a Clean Steam Generator Utility rm COA41480/PK1910 1a SIP System PP 318 0 1a Plant SCADA Network, Domain Server, 327 1a 3 hp, 1750 rpm, 60+ gpm 308 none 1a 3 hp, 1750 rpm, 60+ gpm 322 none 1a Autoclave Rm #321 0 1a Portable CIP skid 171 2005059 1a Portable CIP skid Rock Road 1054701
Page 1 of 8 EXHIBIT B WITMER ROAD PROPERTY - INCLUDED ASSETS GROUPING LEGEND 1A GENERAL BUILDING INFRASTRUCTURE 2A PROCESS EQUIPMENT 3A LAB EQUIPMEN 6A IT EQUIPMENT
FAS SYSTEM EQUIPMENT FAS GROUP # TAG # TAG # ACQ DATE VENDOR - ----- ------ ------------ ------- ---------- -------------------------------- 1a N/A Z-1046 Gas Cylinders, Auto Change- 1a N/A Z-1049 O2 Deward, Auto Change-over 2a N/A AG-1020 2a 1,860 AG-1600 00506 1/1/2003 Lightnin 2a 1,500 AG-1700 00504 1/1/2003 Lightnin 2a N/A AG-2000 2a N/A AG-2001 2a N/A AG-2002 2a N/A AG-2003 2a 1,580 CF-1009 00759 10/23/2003 Separation Equipment 2a 2,176 CF-1012 01429 3/3/2005 Block Scientific 2a 1,445 CF-2500 00524 1/1/2003 Alfa Laval 2a 1,595 CF-2700 00776 10/31/2003 Alfa Laval 2a 1,446 CF-3500 00541 1/1/2003 Alfa Laval 2a N/A F-803 10" diam, 38.5" High 2a N/A FH-1001 CUNO 2a N/A FH-1002 16" diam 2a N/A FH-1004 12" diam 2a N/A FH-1007 12" diam 2a N/A FH-1009 N/A 8" Diam x 27" High 2a 1,453 P-2450 00527 1/1/2003 APV USA 2a 1,461 P-2450 00529 1/1/2003 Allegheny Bradford 2a N/A R-100 2a N/A R-105 2a N/A R-200 1250L, jacketed, agitated 2a 1,456 R-2100 00515 1/1/2003 B. Braun Biotech 2a 1,455 R-2200 00516 1/1/2003 B. Braun Biotech 2a 1,457 R-2300 00519 1/1/2003 B. Braun Biotech 2a 1,459 R-3100 00532 1/1/2003 B. Braun Biotech 2a 1,458 R-3200 00535 1/1/2003 B. Braun Biotech GROUP DESCRIPTION LOCATION SERIAL NUMBER - ----- -------------------------------------------- ---------------------- -------------------- 1a Oxygen System Outside n/a 1a Liquid Oxygen Skid Outside n/a 2a High Shear Agitator Portable #N/A 2a Mixer Attachments-see sys 1500 & 1859 PP 309 R0237425501 & 401 2a Mixer Attachments-see sys 1859 & 1860 PP 308 R0237425501 & 401 2a Mix Tank Agitator 362 #N/A 2a Lightnin Agitator Portable #N/A 2a Lightnin Agitator Portable #N/A 2a Lightnin Agitator Portable #N/A 2a Sorvall RC-3C Plus w/H6000A Rotor Pilot Plant - Rm 320 9500399 2a Sorvall RC-3C Plus centrifuge w/6x1 L roto PP RM 362 0 2a Centrifuge #1-GMP Facility-CF2500 PP RM 326 7217 / 7219/4115645 2a LAPX 404 PP ROOM 320 4126585 2a Centrifuge #2-GMP Facility -CF3500 PP 339 7218/7220/4115482 2a Meissner Filter Housing Portable 1627 2a filter housing Lab 5 #N/A 2a CUNO Depth Filter Portable #N/A 2a CUNO Depth Filter Portable #N/A 2a CUNO Depth Filter Portable #N/A 2a 20" Millipore Filter housing 167 5072 2a Homogenizer PP 326 1-01-302 2a Cooling Exchanger PP 326 2783880 2a 1L reactor 168 WA42401397 2a 4L reactor 168 WA42401397 2a Reactor 302 none 2a 20L Fermenter R2100 PP ROOM 320 1654-15A 2a 200L Fermenter-R2200 PP 320 1655-200A 2a 2000L Fermenter-R2300 PP 320 1656-2000A 2a 20L Fermenter R3100 PP 337 1567-15A 2a 200L Fermenter-R3200 PP RM 337 1658-200A
Page 2 of 8 EXHIBIT B WITMER ROAD PROPERTY - INCLUDED ASSETS GROUPING LEGEND 1A GENERAL BUILDING INFRASTRUCTURE 2A PROCESS EQUIPMENT 3A LAB EQUIPMEN 6A IT EQUIPMENT
FAS SYSTEM EQUIPMENT FAS GROUP # TAG # TAG # ACQ DATE VENDOR - ----- ------ ------------ ------- ---------- -------------------------------- 2a 1,454 R-3300 00536 1/1/2003 B. Braun Biotech 2a N/A R-500 300L, jacketed, agitated 2a 1753 SI-0004 00964 New Brunswick 2a 1,106 SI-0010 00304 1/17/2002 B. Braun Biotech 2a 1,854 SI-0011 00305 1/17/2002 B. Braun Biotech 2a 1,855 SI-0012 00306 1/17/2002 B. Braun Biotech 2a 1,022 SI-0015 00568 9/27/2001 B. Braun Biotech 2a 1,869 SI-0018 00751 10/15/2003 B. Braun Biotech 2a 1,575 SI-0019 01080 10/15/2003 B. Braun Biotech 2a 1,475 TK-1430 00549 1/1/2003 Allegheny Bradford 2a 1,479 TK-1510 00554 1/1/2003 Allegheny Bradford 2a 1,471 TK-1515 00545 1/1/2003 Allegheny Bradford 2a 1,470 TK-1520 00544 1/1/2003 Allegheny Bradford 2a 1,473 TK-1525 00547 1/1/2003 Allegheny Bradford 2a 1,466 TK-1550 00514 1/1/2003 Allegheny Bradford 2a 1,474 TK-1555 00548 1/1/2003 Allegheny Bradford 2a 1,472 TK-1560 00546 1/1/2003 Allegheny Bradford 2a 1,478 TK-1565 00552 1/1/2003 Allegheny Bradford 2a 1,463 TK-1600 00507 1/1/2003 Allegheny Bradford 2a 1,462 TK-1700 00505 1/1/2003 Allegheny Bradford 2a N/A TK-2001 2a N/A TK-2002 2a N/A TK-202 STAINLESS FABRICATION 2a N/A TK-203 3000L, jacketed, agitated 2a 1,467 TK-2400 00522 1/1/2003 Allegheny Bradford 2a 1,468 TK-2600 00528 1/1/2003 Allegheny Bradford 2a 1,469 TK-3400 00537 1/1/2003 Allegheny Bradford 2a N/A TK-5004 2a N/A TK-502 500L, jacketed, agitated 2a N/A TK-503 1000L, jacketed, agitated GROUP DESCRIPTION LOCATION SERIAL NUMBER - ----- -------------------------------------------- ---------------------- -------------------- 2a 2000L Fermenter-R3300 PP RM 337 1659-2000A 2a Reactor 302 n/a 2a Fisher-(2) shakers model C-25KC incubat Lab 5 lab1-890265684 2a Incubating Shaking Cabinets- (3 of the COMMON AREA 413 2208012500274 2a Incubating Shaking Cabinets- (3 of the COMMON AREA 413 108012500283 2a Incubating Shaking Cabinets- (3 of the COMMON AREA 413 2a Incubating Shaking Cabinet PP-rm 316 409012500280 2a Certomat IS benchtop incubating shaker Rm 361 - PP 00101/03, 00102/03 2a Certomat IS benchtop incubating shaker PP Rm 362, 00101/03, 00102/03 2a Portable Tank-TK 1430 PP ROOM 302 8689-4-2-1 2a Portable Tank TK-1510 PP 312 2479785 2a Portable Tank TK-1515 PP ROOM 312 2479786 2a Portable Tank-TK 1520 PP 312 2479694 2a Portable Tank-TK 1525 pp room 312 2479695 2a Portable Tank TK-1550 PP 312 8689-4-2-2 2a Portable Tank TK-1555 PP MOBILE 8689-4-2-3 2a Portable Tank TK-1560 PP 312 8689-4-3-1 2a Portable Tank-TK 1565 PP 322 8689-4-3-2 2a Portable Tank TK-1600 PP ROOM 307 2479665 2a Portable Tank-1700, 200L Atmospheric Ve PP 308 2479634 2a Mixtainer Portable none 2a Mixtainer Portable none 2a HOLDING TANK Lab 5 3822 2a Reactor 171 3822 2a Tank-TK2400 PP 320 8689-5-1-1 2a STATIONARY Tank-TK 2600 PP RM 326 8689-5-1-2 2a Tank-TK-3400 PP RM 337 2479755 2a Mixtainer Portable n/a 2a Reactor 171 n/a 2a Reactor 171 n/a
Page 3 of 8 EXHIBIT B WITMER ROAD PROPERTY - INCLUDED ASSETS GROUPING LEGEND 1A GENERAL BUILDING INFRASTRUCTURE 2A PROCESS EQUIPMENT 3A LAB EQUIPMEN 6A IT EQUIPMENT
FAS SYSTEM EQUIPMENT FAS GROUP # TAG # TAG # ACQ DATE VENDOR - ----- ------ ------------ ------- ---------- -------------------------------- 2a N/A TK-517 600L, jacketed, agitated 2a 1,465 TK-620 00513 1/1/2003 Allegheny Bradford 2a 1,464 TK-630 00512 1/1/2003 Allegheny Bradford 2a 1,477 TK-631 00551 1/1/2003 Allegheny Bradford 2a 1,476 TK-632 00550 1/1/2003 Allegheny Bradford 2a N/A TK-801A 4,000 L, Jacketed w/ agitator 2a N/A TK-801B 4,000 L, Jacketed w/ agitator 2a 2,206 X-5041 01431 6/30/2005 Microfluidics 2a 1,423 Z-1006 00661 3/19/2003 Millipore 2a 1,249 Z-1008 00557 6/19/2002 Cuno Filtration Sales 2a 1,345 Z-1009 00387 11/25/2002 Amersham Biosciences 2a 1,538 Z-1011 00972 8/31/2003 Amersham Bioscience 2a 1,541 Z-1011 00974 8/31/2003 Amersham Bioscience 2a 1,542 Z-1012 00969 8/31/2003 Amersham Biosciences 2a 1,539 Z-1012 00971 8/31/2003 Amersham Bioscience 2a 1,544 Z-1012 00973 8/31/2003 Amersham 2a 1,600 Z-1018 00782 11/30/2003 Stainless Technology 2a 1,570 Z-1018 01014 9/30/2003 Millipore Corporation 2a N/A Z-1024 20L Tk, Mini flat sheet holder & 2a N/A Z-1029 20L Tk, Mini flat sheet holder & 2a 1,657 Z-1031 01116 2/29/2004 Fisher 2a 1,691 Z-1032 01220 4/21/2004 Amersham Biosciences Corp 2a 1,540 Z-1039 00970 8/31/2003 Amersham Bioscience 2a 1,715 Z-1039 01223 5/31/2004 Amersham Biosciences 2a 1,744 Z-1040 01222 6/30/2004 Amersham Biosciences 2a N/A Z-1048 mini TFF holder, peristaltic 2a 479 Z-1100A 00376 2a 1,751 Z-1100B 00377 2a 953 Z-1100C 00383 5/11/2001 B. Braun Biotech 2a 992 Z-1100E 00289 7/18/2001 B. Braun Biotech GROUP DESCRIPTION LOCATION SERIAL NUMBER - ----- -------------------------------------------- ---------------------- -------------------- 2a Reactor 169 n/a 2a Portable Tank-TK620 Portable Vessel PP Mobile 2479693 2a Portable Tank-TK630-Portable Vessel PP ROOM 312 8689-4-1-1 2a Portable Tank-TK-631 250L Portable Vess PP 312 8689-4-1-2 2a Portable Tank, 250L Portable Vessel TK- PP 312 8689-4-1-3 2a Reactor 169 E32702 2a Reactor 169 E32702 2a Low air consumption microfluidizer process PP 0 2a Pellicon Assembly Pilot Plant -320 SKID Z1006 2a Cunocheck 2 Integrity tester PP PORTABLE MC0057 2a 6mm std gradient bioprocess system PP Room 171 1054701 2a Akta Pilot w/ control-see notes Pilot Plant - mobile 0109 3298 2a FRAC 950 Pilot Plant - rm 171 0109 3115 2a AKTA Pilot w/control Pilot Plant - mobile 0109 3295 2a Akta Pilot w/ control Pilot Plant - mobile 0109 3296 2a Frac 950 Pilot Plant - mobile 0109 2786 2a 30L Atmospheric Single Wall Tank Pilot Plant - Mobile 6073 2a Pellicon 2 SS holder assembly Pilot Plant - Rm 167 N/A 2a Small TFF Skid 171 n/a 2a TFF Skid (Small) 169A n/a 2a Labscale TFF System 115V Pilot Plant - Rm 358 P4BN3896015 2a Akta Purifier 100--see sys 1895 Pilot Plant Rm 169A 01118766, 01118419 2a FRAC 950 Pilot Plant -RM 171 0109 2780 2a Akta purifier 100-see sys 1928 Pilot Plant - Rm 171 01129910, 01129977 2a 6mm Standard Gradient Bioprocess System Pilot Plant - Rm 171 1131299 2a 10K TFF Skid 358 n/a 2a B. Braun Biotech Inc.- 2 biostat C 15L WR LAB 5a Room 135A 00257/96, 00256/96 2a B. Braun Biotech Inc.- 2 biostat C 15L WR LAB 5a Room 135A 00257/96, 00256/96 2a Keofit Sample Valve, Biostat-see sys 18 WR LAB 5 01010/97, 01008/97 2a Fermenter WR LAB 5a Room 135A 04087/01
Page 4 of 8 EXHIBIT B WITMER ROAD PROPERTY - INCLUDED ASSETS GROUPING LEGEND 1A GENERAL BUILDING INFRASTRUCTURE 2A PROCESS EQUIPMENT 3A LAB EQUIPMEN 6A IT EQUIPMENT
FAS SYSTEM EQUIPMENT FAS GROUP # TAG # TAG # ACQ DATE VENDOR - ----- ------ ------------ ------- ---------- -------------------------------- 2a 993 Z-1100F 00290 7/18/2001 B. Braun Biotech 2a 994 Z-1100K 00384 7/18/2001 B. Braun Biotech 2a 1,137 Z-119 00912 2/14/2002 Millipore Corporation 2a 650 Z-1200 00733 ALLEGHENY BRADFORD 2a 1,133 Z-1200A 00772 2/28/2002 Allegheny Bradford Corp 2a 649 Z-1300 00732 ALLEGHENY BRADFORD 2a N/A Z-203PC/MT03 00160 3a N/A AE-1013-1 YSI 3a 912 AE-1022 00259 4/4/2001 Fisher Scientific 3a 1,302 AE-1029 00986 9/25/2002 Fisher Scientific 3a 1,536 AE-1041 00648 8/31/2003 Guava Technologies 3a 1,568 AE-1042 01019 9/30/2003 Fisher Scientific 3a 1,723 AE-1051 01231 6/16/2004 Guava Technologies 3a 1,956 AE-1055 01343 8/31/2004 Cambrex Bio Science 3a 1,696 Agilent1 01165 4/30/2004 Agilent Technologies 3a 1,693 Agilent1 01167 4/30/2004 Agilent Technologies 3a 1,896 Agilent1 01168 4/30/2004 Agilent Technologies 3a 1,897 Agilent1 01169 4/30/2004 Agilent Technologies 3a 1,898 Agilent1 01170 4/30/2004 Agilent Technologies 3a 1,899 Agilent1 01171 4/30/2004 Agilent Technologies 3a 1,703 Agilent1 01172 4/30/2004 Agilent Technologies 3a 1,697 Agilent2 01166 4/30/2004 Agilent Technologies 3a 1,694 Agilent2 01173 4/30/2004 Agilent Technologies 3a 1,900 Agilent2 01174 4/30/2004 Agilent Technologies 3a 1,901 Agilent2 01175 4/30/2004 Agilent Technologies 3a 1,903 Agilent2 01177 4/30/2004 Agilent Technologies 3a 765 CF-0149 00149 6/22/2000 Jouan 3a 1,274 CF-1005 00709 8/13/2002 Fisher Scientific 3a N/A CF-1006 Benchtop 3a 1,553 CF-1007 01020 9/18/2003 Fisher Scientific GROUP DESCRIPTION LOCATION SERIAL NUMBER - ----- -------------------------------------------- ---------------------- -------------------- 2a Fermenter-see notes tab-BIOSTAT C-15 Lab 5A 04088/01 2a Fermenter-biostat C15 Lab 5 0414a/01 2a Labscale TFF System WR Lab 3 2a ALLEGHENY BRADFORD-150L FERME WR LAB 5 0 2a 150L ASME code Fermentor with mixer ass Lab 5 0 2a ALLEGHENY BRADFORD-1000L FERM WR LAB 5 0 2a CONTROLLER Lab 5 3241-1-1 3a ANALYZER Lab 8 #N/A 3a Spectrophotometer WR LAB 6 Room 135 3FGD037003 3a Thermo-spectronic genesys 20 spectropho PP-Rm 316 neose # AE-1029 3a Guava PCA System-see sys 1866 PP 362 GTI-0300372, DPDL831 3a Gensys 5 spectophotometer package Pilot Plant - Rm 361 3V8F157005 3a Guava PCA System Pilot Plant - Rm 337 GTI-0400438 3a Channel Reader w/ incubator UV Genrc Lab 1 QC 1919188 3a Micro Vacuum Degasser WR Lab 9 - Rm 146 JP40714634 3a 1100 HPLC System with Cerity Software P WR Lab 9 - Rm 146 3a 1100 HPLC System with Cerity Soft Packg WR Lab 9 - Rm 146 3a 1100 HPLC Sys w/ Cerity Soft Packg-see WR Lab 9 - Rm 146 3a 1100 HPLC Sys w/ Cerity Soft Packg-sys WR Lab 9 - Rm 146 3a 1100 HPLC Sys w/ Cerity Soft Packg-see WR Lab 9 - Rm 146 3a GMP Stand alone Bundle Cerity, IQ/OQ WR Lab 9 - Rm 146 FRB40801S1 3a Micro Vacuum Degasser Lab 9 - Rm 146 JP40714765 3a 1100 HPLC System with Cerity Software P WR Lab 9 - Rm 146 3a 1100 HPLC System with Cerity Soft Packg WR Lab 9 - Rm 146 3a 1100 HPLC Sys w/ Cerity Soft Packg-see WR Lab 9 - Rm 146 3a 1100 HPLC Sys w/ Cerity Soft Packg-sys WR Lab 9 - Rm 146 3a Centrifuge MR1812 WR LAB 4 Room 132 49709025 3a Marathon 16km microcentrifuge WR LAB 6 Room 135B 207N0037 3a Centrifuge 337 04004 3a Eppendorf Centrifuge 541R w/o Rotor 115 Pilot Plant - Rm 316 5426-07848
Page 5 of 8 EXHIBIT B WITMER ROAD PROPERTY - INCLUDED ASSETS GROUPING LEGEND 1A GENERAL BUILDING INFRASTRUCTURE 2A PROCESS EQUIPMENT 3A LAB EQUIPMEN 6A IT EQUIPMENT
FAS SYSTEM EQUIPMENT FAS GROUP # TAG # TAG # ACQ DATE VENDOR - ----- ------ ------------ ------- ---------- -------------------------------- 3a N/A CF-1010 Benchtop 3a N/A CF-1011 Benchtop 3a 2,098 CF-1377 01377 10/31/2004 Amersham Biosciences Corp 3a 1,643 EDAS-290 01114 1/31/2004 Fisher 3a 730 EV-522 00129 4/24/2000 Pope Scientific 3a 526 EV-522 00977 3a 265 FD-0965 00965 3a N/A FP-100 SIM AMINCO 3a N/A FPLC-1 AMERSHAM 3a 1,313 FPLC-2 00375 10/11/2002 Amersham Biosciences Corp 3a 2,124 HPLC-1370 01367 11/30/2004 Agilent Technologies 3a 2,125 HPLC-1370 01368 11/30/2004 Agilent Technologies 3a 2,126 HPLC-1370 01369 11/30/2004 Agilent Technologies 3a 2,123 HPLC-1370 01370 11/30/2004 Agilent Technologies 3a 1,576 KF-02 01078 10/23/2003 Fisher Scientific 3a 729 M-01 00107 4/24/2000 Fisher Scientific 3a 2,127 MFT03 (HPLC 1370 01371 11/30/2004 Agilent Technologies 3a 1,243 MI-200 00583 6/30/2002 Millipore Corporation 3a 1,617 MPR-01 00787 12/16/2003 Molecular Devices 3a N/A N/A CENTRIFUGE 3a 1,671 OS-01 01150 3/31/2004 Fisher 3a 1,625 P-2460 01113 12/31/2003 APV North America 3a 661 PO-01 00945 VWR Scientific Products 3a N/A QC01 Beckman 3a N/A QC05-1 Dionex 3a N/A QC05-2 Dionex 3a N/A QC-15 3a 855 RI-71 00818 1/18/2001 Beckman Coulter, Inc 3a 1,276 SB-100 00705 8/19/2002 Fisher Scientific 3a 897 SDWATERS 00321 3/6/2001 Dell Direct Sales GROUP DESCRIPTION LOCATION SERIAL NUMBER - ----- -------------------------------------------- ---------------------- -------------------- 3a Centrifuge 361 #N/A 3a Centrifuge 362 #N/A 3a Fraction Collector 200 Cold Room 1130435 3a EDAS 290 EPI Win 110V, Demo Unit WR Lab 9 ROOM 132 EKT03201771 3a Liquid pump distilbate POPE (see also F Room 168 0 3a Pope Scientific, Inc.-addition to FAS # PP-Rm 168 0 3a Fisher - Freeze Dryer (Labconco) Common Lab Area 413 #N/A 3a CELL PRESS 413 #N/A 3a HPLC SYSTEM - FPLC Lab 3 #N/A 3a AKTA fplc WR Lab 3 1057859 3a 1100 Thermostatted Well-plate Sampler Lab 7 DE43603782 3a 1100 Thermostatted column Compartment Lab 7 DE43642389 3a 1100 Diode-array Detector Lab 7 DE43623550 3a 1100 Binary Pump Lab 7 DE43616461 3a KFD Titrino 758/B-20 WR LAB 9 10576598 3a Microscope- Zeiss- Axiostar Lab 1 33485 3a HPLC 2D ChemStation S/W License Bundle Lab 7 USU4390DW3 3a Milliflex Vacuum Filtration System LAB 1 0 3a Spectramax Plus 384 microplate reader w QC 147 MN03884 3a FISHER Lab 6 51200419 3a Osmette Osmometer WR Lab 9 HE0309B 3a APV1000 Laboratory Homogenizer Lab 2 1-0.3785 3a VWR- polax 2L display polarimeter QC 146 990223 3a Beckman HPLC (Autosampler, detector, Lab 9 252645 3a Dionex HPLC (Autosampler, detector, Lab 9 n/a 3a Dionex HPLC (Autosampler, detector, Lab 9 n/a 3a AUTOSAMPLER Lab 9 042/00821 3a Shodex Refractive Index Detector-RI-71, WR LAB 9 3a Sonic Dismembrator WR LAB 6 Room 135b FS1392 3a Dell 866 mhz F9D1D01
Page 6 of 8 EXHIBIT B WITMER ROAD PROPERTY - INCLUDED ASSETS GROUPING LEGEND 1A GENERAL BUILDING INFRASTRUCTURE 2A PROCESS EQUIPMENT 3A LAB EQUIPMEN 6A IT EQUIPMENT
FAS SYSTEM EQUIPMENT FAS GROUP # TAG # TAG # ACQ DATE VENDOR - ----- ------ ------------ ------- ---------- -------------------------------- 3a 1,615 SP-0495 00495 12/31/2003 Digilab 3a 1,712 SP-1199 01199 5/27/2004 Amersham Biosciences 3a 28 SS02 00994 3a N/A TOC-01 00224 TOC 3a 685 UV-101 00902 1/31/2000 Shimadzu Scientific Instr 3a N/A V-512A w/ distillation columns 3a N/A V-513A w/ distillation columns 3a 895 00223 3/15/2001 Sievers Instruments Inc 3a 1,826 00225 3/15/2001 Sievers Instruments Inc 3a N/A FISHER 3a N/A WATERS 6a 841 MT02 00985 11/17/2000 Dell Direct Sales 6a 714 00021 3/9/2000 Copy-Quik 6a 803 00024 8/24/2000 Copi-Quik 6a 775 00096 6/30/2000 Universal Access 6a 1,808 00160 9/22/2000 Dell Direct Sales 6a 829 00174 10/6/2000 Affiliated Business Solut 6a 946 00209 4/13/2001 Dell Direct Sales 6a 955 00244 5/17/2001 Hello Direct 6a 1,064 00308 11/28/2001 Dell Marketing LP 6a 1,251 00373 Parente Tech 6a 1,290 00389 8/1/2002 Vistacom 6a 1,405 00395 2/14/2003 CDW Computer Services 6a 848 00428 12/31/2000 Software House Inter 6a 1,452 00566 1/1/2003 Techniserv 6a 1,275 00590 8/19/2002 CDW 6a 1,546 00626 8/31/2003 ePlus Technologies 6a 1,127 00738 1/31/2002 Virtus Partners, LLC 6a 1,339 00918 10/30/2002 TrueTime, Inc 6a 625 00943 META CHEM TECHNOLOGIES GROUP DESCRIPTION LOCATION SERIAL NUMBER - ----- -------------------------------------------- ---------------------- -------------------- 3a U2810 UV/Vis Spectrophotometer Lab 5 5860016 3a Ultrospec 4300 Pro, plum WR Lab 3 80-2112-45 3a Beckman Centrifuge & Rotors (2) WR Lab 3 #N/A 3a Sievers Lab 9 01022453/AS928 3a UV-Vis Detector Spectro Lab 6 200505 3a Rotovap 168 US 53400689 3a Rotovap 168 US 53400689 3a Portable TOC Package Sievers Model 800- WR LAB 9 Room 146 TOC0102-2453 3a Portable TOC Package Sievers Model 800- LAB 9 Room 146 TOC0102-2453 3a MICROSCOPE Lab 5A #N/A 3a PHOTO DIODE ARRAY DETECTOR Lab 8 #N/A 6a Dell 866Mhz GX110 mini tower Lab 5a 61SF401 6a Ricoh Copier Receptionist Area 57925 6a Digital Copier & Digital Feeder-Ricoh Copy Room 59360 6a Compaq Server Rack Server Room 190 0 6a Dell 733 Mhz-see sys 819 Room 135 GVZL101 6a Fax Machine 3170 Reception Area UYP18793 6a Dell 866 mhz IT 5CX7H01 6a Polycom Viewstation-see Notes tab Conf Room B 0 6a Pentium III-see sys 1851 WR LAB 4 ROOM 132 3CC2011 6a Avaya Prologix Phone System-201 Witmer 6a Soundstation for lunchroom phonecloset-blackrac 0 6a SCADA Rack Accessories Server Room 0 6a Server for Neose West WR D045DKH1K161 6a SCADA/BOP System WR SERVER 0 6a CPQ EVO N800V 8/1.6 20GB Office XPP P. Toland Trailer 5Y27KSQZW00J 6a Cisco Catalyst 3550 24 10/100 inline po Server Room CAT0713Y0S3 6a HP Autoloader WR Server Room 0 6a Synchronized network time server server room 6a Canon Fax (admin area) UYG34350 0
Page 7 of 8 EXHIBIT B WITMER ROAD PROPERTY - INCLUDED ASSETS GROUPING LEGEND 1A GENERAL BUILDING INFRASTRUCTURE 2A PROCESS EQUIPMENT 3A LAB EQUIPMEN 6A IT EQUIPMENT
FAS SYSTEM EQUIPMENT FAS GROUP # TAG # TAG # ACQ DATE VENDOR - ----- ------ ------------ ------- ---------- -------------------------------- 6a 1,648 01115 1/31/2004 Suppression Systems Inc 6a 1,273 1273NT 8/30/2002 B. Braun Biotech 6a 1,277 1277NT 8/30/2002 Rumsey Electric 6a 1,295 1295NT 9/18/2002 Rumsey Electric 6a 1,344 1344NT 11/11/2002 Ionics Instruments 6a 1,379 1379NT 12/31/2002 The MNM Group, Inc 6a 1,588 1588NT 10/7/2003 ePlus Technology 6a 1,641 1641NT 12/31/2003 CDW 6a 776 776NT 6/30/2000 Associated Building 6a 6a 6a 6a 6a 6a 6a 6a 6a 6a 6a 6a 6a 1,144 2/11/2002 Rodata GROUP DESCRIPTION LOCATION SERIAL NUMBER - ----- -------------------------------------------- ---------------------- -------------------- 6a Fike SHP/Clean Agent Fire Suppression S Server Room 0400885 - tank 6a PCI Bus Board 0 6a RSLogix500 Programming Software SCDA laptop 0 6a SCADA Software software 0 6a Analog motherboard for model #400 TOC a Computer Board 0 6a Install Additional Cable trays, panels in new used in Room 190 0 6a Wireless Installation 0 6a APC Rack -mount LCD Monitor/Keyboard Drawr-Citrix-see #1605,16 0 6a Projection Screen in Lunch Room #N/A 6a One 4-port KVM switch Room #190 6a One 16-port KVM switch (SCADA Rack) Room #190 6a One APC UPS 3000 Room #190 6a One APC Netshelter Wall Mounted Rack Room #190 6a One Cisco 3500-48 port switch (SCADA net Room #190 FAB0549Q28Q 6a One Nextel BDA (actually owned by Nextel Room #190 6a Five Cisco Aironet 802.11 B access points Distributed throughout 6a Three AIR-ANT2012 and Two AIR-ANT59 Distributed throughout 6a Two infrastructure racks and patch panels(ca Room #190 6a One HP OfficeJet G95 (Fax/Scanner/Color Printer/Copier) SG19E13TJ 6a One HP 2200D Black & White Laser Printer (includes a network card-n JPGG72421 6a One HP 2200D Black & White Printer (local printer) CNDRC55654 6a Visual Concert-see notes tab-goes with FAS Conf Rm B 0
Page 8 of 8 102 WITMER ROAD, HORSHAM, PA EXHIBIT B-1 EXCLUDED PERSONAL PROPERTY (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 36 EXHIBIT B-1 WITMER ROAD PROPERTY - EXCLUDED ASSETS
FAS EQUIPMENT FAS SYSTEM # TAG # TAG # ACQ DATE VENDOR - -------- ----------------- ------- ---------- --------------------------------- 910 AE-1005 00226 4/4/2001 BioWhittaker N/A AE-1012 FISHER 1,000 AE-1013 00272 8/3/2001 Ecogen 1,139 AE-1021 00567 2/14/2002 Nova Biomedical 1,217 AE-1023 00388 5/31/2002 GE Kaye 1,300 AE-1035 00708 9/25/2002 Fisher Scientific 1,526 AE-1038 00594 7/30/2003 Guava Technologies, Inc 2,066 Agilent3 01330 9/30/2004 Agilent Technologies 2,078 Agilent3 01331 9/30/2004 Agilent Technologies 2,079 Agilent3 01332 9/30/2004 Agilent Technologies 2,080 Agilent3 01333 9/30/2004 Agilent Technologies 2,081 Agilent3 01334 9/30/2004 Agilent Technologies 2,082 Agilent3 01335 9/30/2004 Agilent Technologies 2,083 Agilent3 01336 9/30/2004 Agilent Technologies 2,065 Agilent4 01323 9/30/2004 Agilent Technologies 2,072 Agilent4 01324 9/30/2004 Agilent Technologies 2,073 Agilent4 01325 9/30/2004 Agilent Technologies 2,074 Agilent4 01326 9/30/2004 Agilent Technologies 2,075 Agilent4 01327 9/30/2004 Agilent Technologies 2,076 Agilent4 01328 9/30/2004 Agilent Technologies 2,077 Agilent4 01329 9/30/2004 Agilent Technologies N/A AX-300-SE ALPHA TECH N/A B10 KENMORE N/A BF-0001 SORVALL 1,594 CF-00778 00778 10/31/2003 Alfa Laval N/A CF-1002 EPPENDORF 674 CF-1003 00114 1/21/2000 Kendro Laboratory Product 1,676 CF-1241 01241 1/1/2004 Fisher Scientific 2,128 CF-1366 01366 11/30/2004 Fisher Scientific 2,215 CF-1436 01436 8/25/2005 Fisher Scientific 2,237 CF-4-5810 01454 2/22/2006 Fisher Scientific 708 CF-SS03 00115 3/23/2000 Kendo N/A CT-01 Eppendorf N/A CT-03 Eppendorf 2,091 DP-08 (HPLC 1353) 01357 7/31/2004 Agilent Technologies 1,036 F-1004 00718 10/11/2001 Fisher Scientific N/A F-1005 MILLIPORE N/A F-201 PD Pump, frame, cartridge holders N/A F-204 PD Pump, frame, cartridge holders N/A F-501 PD Pump, frame, cartridge holders N/A F-506 PD Pump, frame, cartridge holders N/A F-805 Temporary Use N/A H-0006 6 Foot 1,164 HPLC-0320 00320 3/31/2002 Amersham Biosciences 2,059 HPLC-0923 01358 9/30/2004 Agilent Technologies FAS SYSTEM # DESCRIPTION LOCATION SERIAL NUMBER - -------- ---------------------------------------------------------------- ------------------- ------------------- 910 Standard Kinetic System - biowhittaker Lab 1 154807 N/A OVEN Lab 8 1815 1,000 Biochemistry Analyzer Lab 8 0 1,139 Nova BioProfile 300A WR LAB 8 T03B01120 1,217 ValidatorX2000 GE Kaye (and related sof PP RM 337 205027 1,300 Microscope, binocular WR LAB 8 46961 1,526 Guava PCA system w/Via Count Module Lab 8 GTI-0300337 2,066 HPLC system with Chem Station & ChemStore software appl Lab 9 JP40718212 2,078 HPLC system with Chem Station & ChemStore software appl - #2066 Lab 9 DE43616213 2,079 HPLC system with Chem Station & ChemStore software appl - #2066 Lab 9 DE43603676 2,080 HPLC system with Chem Station & ChemStore software appl - #2066 Lab 9 DE13209035 2,081 HPLC system with Chem Station & ChemStore software appl - #2066 Lab 9 DE43641606 2,082 HPLC system with Chem Station & ChemStore software appl - #2066 Lab 9 DE43623141 2,083 HPLC system with Chem Station & ChemStore software appl - #2066 Lab 9 MXL4390MP1 2,065 HPLC systems with Chem Station & Chemstore software appl Lab 9 JP40718198 2,072 HPLC systems with Chem Station & Chemstore software appl Lab 9 DE43616218 2,073 HPLC systems with Chem Station & Chemstore software appl - #2065 Lab 9 DE40503664 2,074 HPLC systems with Chem Station & Chemstore software appl - #2065 Lab 9 DE13208979 2,075 HPLC systems with Chem Station & Chemstore software appl - #2065 Lab 9 DE43641580 2,076 HPLC systems with Chem Station & Chemstore software appl - #2065 Lab 9 DE43623142 2,077 HPLC systems with Chem Station & Chemstore software appl - #2065 Lab 9 MXL4390MRY N/A DEVELOPER Lab 4 #N/A N/A FREEZER Lab 6 N/A N/A BIO-FUGE BENCHTOP Lab 3 #N/A 1,594 LAPX 404 Centrifuge Room 135 4126586 N/A CENTRIFUGE Lab 8 92364 674 Kendro Laboratory-Centrifuge & Rotor WR LAB 8 9902806 & 9960052 1,676 Eppendorf Centrifuge 5414R w/o Roto 115 Lab 4 - Rm 132 5426 07559 2,128 Centrifuge Fisher Accuspin 3R Lab 7 40411879 2,215 Refrigerated Eppendorf Centrifuge - 5415R 14268 2,237 Eppendorf Cent Mdl 5810R Lab 4 33806 708 RC-5B plus Centrifuge 208v/60hz & GSA S common area 9902150 N/A Centrifuge Lab 9 5415 91857 N/A Eppendorf Model 5810 Centrifuge (RPM and time) Lab 9 #N/A 2,091 HPLC System - See 1942 Lab 7 FRB250TSZ 1,036 Gradient system with TOC Monitor' WR LAB 9 Room 146 0 N/A TFF UNITS (5 sqft qty 2) Lab 2 #N/A N/A Hollow Fiber Skid Rock Road #N/A N/A R.O. Skid Rock Road #N/A N/A Hollow Fiber Skid Rock Road #N/A N/A R.O. Skid Rock Road #N/A N/A R.O. Skid RR 403a #N/A N/A Biosafety Cabinet Lab 1 233370 1,164 AKTA Explorer WR Lab 2 1032333 2,059 Agilent HPLC system Lab 3 JP40717490
Page 1 of 6 EXHIBIT B-1 WITMER ROAD PROPERTY - EXCLUDED ASSETS
FAS EQUIPMENT FAS SYSTEM # TAG # TAG # ACQ DATE VENDOR - -------- ----------------- ------- ---------- --------------------------------- 2,112 HPLC-0923 01359 9/30/2004 Agilent Technologies 2,113 HPLC-0923 01360 9/30/2004 Agilent Technologies 2,114 HPLC-0923 01361 9/30/2004 Agilent Technologies 2,115 HPLC-0923 01362 9/30/2004 Agilent Technologies 2,116 HPLC-0923 01363 9/30/2004 Agilent Technologies 2,117 HPLC-0923 01364 9/30/2004 Agilent Technologies 1,669 HPLC-1156 01156 3/19/2004 Amersham Biosciences 1,680 HPLC-1200 01200 4/23/2004 Amersham Biosciences Corp 1,681 HPLC-1203 01203 4/23/2004 Amersham Biosciences Corp 1,892 HPLC-1203 01204 4/23/2004 Amersham Biosciences Corp 2,061 HPLC-1348 01344 9/30/2004 Agilent Technologies 2,092 HPLC-1348 01345 9/30/2004 Agilent Technologies 2,093 HPLC-1348 01346 9/30/2004 Agilent Technologies 2,094 HPLC-1348 01347 9/30/2004 Agilent Technologies 2,095 HPLC-1348 01348 9/30/2004 Agilent Technologies 2,096 HPLC-1348 01349 9/30/2004 Agilent Technologies 2,097 HPLC-1348 01350 9/30/2004 Agilent Technologies 1,942 HPLC-1353 01351 7/31/2004 Agilent Technologies 2,086 HPLC-1353 01352 7/31/2004 Agilent Technologies 2,087 HPLC-1353 01353 7/31/2004 Agilent Technologies 2,088 HPLC-1353 01354 7/31/2004 Agilent Technologies 2,089 HPLC-1353 01355 7/31/2004 Agilent Technologies 2,090 HPLC-1353 01356 7/31/2004 Agilent Technologies 1,955 HPLC-1377 01337 8/31/2004 Amersham Biosciences Corp 2,060 HPLC-1377 01338 9/30/2004 Amersham Biosciences 2,085 HPLC-1377 01339 8/31/2004 Amersham Biosciences Corp 1,734 HPLC-1430 01340 6/29/2004 Amersham Biosciences 2,084 HPLC-1430 01341 6/29/2004 Amersham Biosciences 1,938 HPLC-1430 01342 7/14/2004 Amersham Biosciences N/A IN-01 FISHER 2,188 IN-1423 01423 4/30/2005 Fisher Scientific 2,205 IN-1439 01439 6/29/2005 Fisher N/A IN-4-008 PRECISION SCIEN 695 IR-100 00106 2/29/2000 Nicolet Instrument Corpor 814 IR-100 00156 9/29/2000 Savant Instruments N/A JB-01 Boekel N/A Lab PC (TOC-5054) Compaq N/A Lab PC (Z-5056) Dell 1,692 M-02 01178 4/30/2004 Fisher Scientific N/A MC-CR01 N/A MC-CR-02 N/A MC-CR03 N/A MC-CR-04 N/A MC-CR-07 1,414 MF-0398 00398 1/1/2003 Microfluidics FAS SYSTEM # DESCRIPTION LOCATION SERIAL NUMBER - -------- ---------------------------------------------------------------- ------------------- ------------------- 2,112 Agilent HPLC system - See 2059 Lab 3 DE40916011 2,113 Agilent HPLC system - See 2059 Lab 3 DE40522833 2,114 Agilent HPLC system - See 2059 Lab 3 DE40541126 2,115 Agilent HPLC system - See 2059 Lab 3 DE40503602 2,116 Agilent HPLC system - See 2059 Lab 3 DE13208743 2,117 Agilent HPLC system - See 2059 Lab 3 FRB4250TT1 1,669 Akta Purifier 100 Lab 3 1127076 1,680 Akta Purifier 100-see sys 1890-1891 WR Lab 2 1,681 Akta Purifier 100-see sys 1892-1893 WR Lab 3 1,892 Akta Purifier 100-see sys 1681, 1892 WR Lab 3 2,061 HPLC System Lab 4 JP40718016 2,092 HPLC System - See 2061 Lab 4 DE40916072 2,093 HPLC System - See 2061 Lab 4 DE43623058 2,094 HPLC System - See 2061 Lab 4 DE40541424 2,095 HPLC System - See 2061 Lab 4 DE40503652 2,096 HPLC System - See 2061 Lab 4 DE13208932 2,097 HPLC System - See 2061 Lab 4 USU43006TT 1,942 HPLC System Lab 7 JP40716672 2,086 HPLC System - See 1942 Lab 7 DE40915661 2,087 HPLC System - See 1942 Lab 7 DE40503439 2,088 HPLC System - See 1942 Lab 7 DE13208151 2,089 HPLC System - See 1942 Lab 7 DE40540101 2,090 HPLC System - See 1942 Lab 7 DE40522258 1,955 AKTA Purifier 100, Pv908 and IV-908 Lab 7 1137326 2,060 Pump P-960 - see also system #1955 Lab 7 1144778 2,085 AKTA Purifier 100, Pv908 and IV-908, Fr Lab 7 1139661 1,734 Akta Purifier 100 Lab 7 1133946 2,084 Akta Purifier 100, Frac-950 - #1734 Lab 7 1133965 1,938 Pump P-960-part of AKTA Purifier 100 Lab 7 1135510 N/A INCUBATOR Lab 8 70B00098 2,188 Precision Incubators Lab 7 0 2,205 Precision Refrigerated Incubator Lab 3 0 N/A INCUBATOR Lab 4 9208-008 695 SpectrometerAvatar 360 WR LAB 9 AeA0001620 814 Speedvac DDA Concentrator(SC250DDA#4898 Lab 9 SC250DDA#4898 N/A Jitter Bug Lab 9 AEA0001620 N/A CPU for Sievers 900 Lab 9 MXL44104K5 N/A CPU for Densitometer Lab 9 MXL44104K5 1,692 Intervoskop 40C microscope QC 147 3826000111 N/A Chart Recorder for QI-01 Lab 1 3826000111 N/A Chart Recorder for QZ-03 Lab 1 3826000111 N/A Chart Recorder for QI-04 Lab 1 3826000111 N/A Chart Recorder for MZ-33 Lab 1 3826000111 N/A Chart Recorder for MZ-35 Lab 1 3826000111 1,414 Microfluidizer Lab 6 - Scale Up 2000011A
Page 2 of 6 EXHIBIT B-1 WITMER ROAD PROPERTY - EXCLUDED ASSETS
FAS EQUIPMENT FAS SYSTEM # TAG # TAG # ACQ DATE VENDOR - -------- ----------------- ------- ---------- --------------------------------- N/A MFT02 HP 767 MI-100 00108 6/30/2000 Millipore Corporation N/A MZ-11 17.9 cu. Ft. N/A MZ-17 HOTPOINT N/A MZ-31 WOODS N/A MZ-3-2 KENMORE 825 MZ-33 00161 10/20/2000 VWR Scientific 1,259 MZ-35 00303 7/23/2002 Labrepco, Inc. 1,705 MZ-4-1 01240 5/27/2004 Fisher 920 MZ-4-4 00227 4/20/2001 Fisher Scientific N/A MZ-45 24.4 cu. Ft. N/A MZ-4-5 FISHER SCIENTIF N/A MZ-4-6 FRIDGIDARE 2,189 MZ-4-7 01424 4/30/2005 Fisher Scientific 1,735 MZ-48 01242 6/30/2004 Fisher Scientific 2,212 MZ-4-8 01433 7/8/2005 Fisher Scientific 2,170 MZ-52 01415 2/17/2005 Fisher Scientific 1,954 MZ-7-1 01260 8/25/2004 Fisher Scientific 2,155 MZ-7-2 01387 12/17/2004 Fisher Scientific /Kendro N/A No # HP N/A No # N/A N/A No # Stovall 1,159 NT-105 00707 3/15/2002 Fisher Scientific 1,296 NT-106,107,108 00531 9/13/2002 ACME Cryogenics N/A NT-109 Taylor Wharton 10K 2,177 NT-110 01417 3/31/2005 Airgas East 1,597 NT-112 00493 11/30/2003 Anza Lab Services 1,261 P-0743 00743 7/31/2002 Penn Valve 2,185 P-2 01427 4/26/2005 Millipore N/A P-512 00991 PUMP N/A P-703, F-1006 LAPTOP N/A P-705 MASTERFLEX 641 QC02-1 00774 10/14/1999 BECKMAN COULTER 411 QC02-1 00869 N/A QC03 Beckman N/A QC04 Dionex 2,175 QC-06 01421 3/29/2005 ESA, Inc. N/A QI-01 10 cu.ft. 20deg.C to 65deg.C 981 QI-04 00266 7/26/2001 Fisher Scientific 2,171 QI-07 01414 2/28/2005 Fisher Scientific N/A QM-04 N/A QZ-03 17 cu.ft 2deg. C to 8deg. C N/A RP-0001 VWR N/A RP-0002 VWR N/A SC-003 DENVER INSTRUME FAS SYSTEM # DESCRIPTION LOCATION SERIAL NUMBER - -------- ---------------------------------------------------------------- ------------------- ------------------- N/A CPU Lab 7 MXLL4410FST 767 Milliflex sensor II WR LAB 1 372UCE N/A -20 degrees C Freezer 201 Witmer S510354305 N/A REFRIG/FREEZER Lab 8 GS554308 N/A REFRIGERATOR Lab 2 D6828038JF N/A FREEZER Lab 3 WB95103644 825 Refrigerator Lab 1 1,259 Harris Undercounter freezer Lab 1 0 1,705 Refrigerator, general purpose 49cu ft 1 Lab 4 - Rm 132 403N0013 920 Freezer Lab 4 P28L-523405RL N/A -70 freezer 201 Witmer U07D-168667-UD N/A FREEZER Lab 4 102N0052 N/A FREEZER Lab 4 WB30814521 2,189 Fisher Isotemp Lab refrigerator w/ recorder and alarm Lab 7 0 1,735 72 cu ft glass front refrigerator w/cha QC Lab 10 406N0002 2,212 Isotemp plus lab freezer with recorder and alarm 506N0004 2,170 72 cu. ft. refrigerator w/ alarm & day chart recorder 201 Witmer 0 1,954 72cuft chromatography refrigertor w/ al Lab 7 408N0004 2,155 Freezer (-86) 32 CUFT Lab 7 Y190-274184-Z0 N/A Scanjet 8200 scanner Lab 9 none N/A Cuvette washer apparatus & pump Lab 9 #N/A N/A Belly Dancer Lab 9 none 1,159 Locator jr plus cryovat w/monitor Lab 8 509020211379 1,296 Cryostorage system-Taylor Wharton PP RM 328 NT-106-108 N/A Cryovat 201 Witmer 562-018-U5 2,177 10K-Kryos - Taylor Wharton Cryovat 201 Witmer 0 1,597 Kryos liquid nitrogen cryofreezer 201 Warehouse 555-003-S21 1,261 Portable Pump Trolley Room 135 0 2,185 Pelicon2 Filter Holder Assembly + Pump LAb 2 5000-00917 N/A WATSON MARLOW Lab 5 7031206 N/A PUMP + Filter Assembly Lab 2 02179 N/A PUMP Lab 5 A94002784 641 Beckman Coulter-32 Karat Workstation Lab 9, Rm 146 8189E1UKCBP0L1 411 Beckman Instruments, Inc. - Model 507 e WR LAB 9 6656 N/A Beckman HPLC (Autosampler, detector, pump) Rock Road 127468 N/A Dionex HPLC (Autosampler, detector, pump) Lab 9 n/a 2,175 Corona charged aerosol detector and installation Lab 9 CO-0131 N/A Incubator Lab 1 9410011 981 Incubator WR LAB 1 601061579 2,171 Precision Model 815 refrigerated incubator RM 147 0 N/A pH meter/Conductivity meter Lab 9 11048304 N/A 2-8 degrees C Refrigerator Lab 1 WA42401397 N/A ROCKING PLATFORM Lab 3 040119A N/A ROCKING PLATFORM Lab 3 none N/A SCALE Lab 3 N0103309
Page 3 of 6 EXHIBIT B-1 WITMER ROAD PROPERTY - EXCLUDED ASSETS
FAS EQUIPMENT FAS SYSTEM # TAG # TAG # ACQ DATE VENDOR - -------- ----------------- ------- ---------- --------------------------------- 931 SC-0429 00429 4/19/2001 Nextran/Mettler N/A SC-1000 METTLER TOLEDO 739 SC-1001 00145 5/25/2000 Fisher SC-1002 5/25/2000 DENVER INSTR. N/A SC-1006 METTLER N/A SC-610 DENVER INSTRUME 1,019 SI-0013 00302 9/27/2001 B. Braun Biotech 965 SI-0014 00260 6/25/2001 B. Braun Biotech 1,946 SI-0023 01263 07/28/04 VWR Scientific 615 SP-0796 00796 AMERSHAM PHARMACIA BIO 2,121 SP-1372 01372 11/11/2004 Amersham Biosciences Corp N/A SR-01 Branson 1510 1,533 ST-0627 00627 8/21/2003 Fisher 1,577 TC-01 01076 10/23/2003 Labrepco 602 TK-1000 00769 2,180 TOC-5054 01437 3/31/2005 Ionics N/A UR-MZ-48 N/A UR-SI-0023 783 UV-01 00109 7/14/2000 Agilent Technologies 1,440 UV-01 00667 5/20/2003 Agilent Technologies 523 UV-01 00688 1,754 UV-01 00946 N/A VT-01 Fisher Scientific N/A VT-02 Thermolyne N/A VT-03 Thermolyne N/A VT-117 N/A WB-06 Fisher Scientific N/A WB-07 N/A WB-LAB6-1 FISHER SCIENTIF N/A Z-0124 WAVE N/A Z-1026 1,658 Z-1030 01117 2/29/2004 Fisher 1,599 Z-1041 00783 11/30/2003 Stainless Technology 2,108 Z-1041 01406 10/31/2004 Herman Goldner Co., Inc. 2,156 Z-1047 01386 12/28/2004 Millipore Corporation 1,833 Z-1100D 00378 5/11/2001 B. Braun Biotech 1,219 Z-1100G 00379 5/22/2002 B. Braun Biotech 1,237 Z-1100H 00380 5/22/2002 B. Braun Biotech 1,238 Z-1100I 00381 5/22/2002 B. Braun Biotech 1,752 Z-1100J 00382 1,001 Z-117 00273 8/3/2001 Ecogen 2,234 Z-5056 01451 1/27/2006 Eastman Kodak Co 1,166 00342 3/31/2002 Amersham Biosciences 1,319 00424 10/29/02 VWR Scientific 1,320 00425 10/29/02 VWR Scientific FAS SYSTEM # DESCRIPTION LOCATION SERIAL NUMBER - -------- ---------------------------------------------------------------- ------------------- ------------------- 931 Floor Scale WR Lab 2 0 N/A SCALE Lab 2 5075335-5FA 739 Weigh Scale TR-104 WR Lab 8 1914148 SCALE Lab 6 T0122875 N/A SCALE Lab 5A E20782 N/A SCALE Lab 3 0077924 1,019 Incubating Shaking Cabinet Lab 8 308012500240 965 Incubating Shaking Cabinet Lab 8 809002500211 1,946 Refrigerated Shaking Incubator Lab 10-WR 615 AMERSHAM PHARMACIA BIOTECH ULTROSPEC 3 Lab 4 ROOM 132 76803 2,121 Ultrospec 4300Pro UV/V is spectrophotometer Lab 7 80-2112-46 N/A Sonicator Lab 9 80-2112-46 1,533 Sterilmatic steam pressure sterilizer Lab 6 215207 1,577 DEMO Biometra Tgradient 96 Thermocycler WR LAB 9 1304242 602 Loeb Equipment WR Lab 5 0 2,180 Model 900 Laboratory TOC Analyzer w/Autosampler & DataGuard Lab 9 0503-0467 N/A Chart Recorder for MZ-48 Lab 10 01022453/AS928 N/A Chart recorder for SI-0023 Lab 5 01022453/AS928 783 Automated sipper system for 8453 for HP lab 109 Rm 146 10714-0013 1,440 Peltier temp controller WR Lab 9 - Room 146 CN22500124 523 Hewlett-Packard HP8453 gen purpose UV-V WR LAB 9 us53400689 1,754 Dell Direct Sales (2) DELL DIMENSIONS WR LAB 9 URWDH/09VQM N/A Mini vortexer Lab 9 2-214214 N/A Mini vortexer Lab 9 871000210826 N/A Mini vortexer Lab 10 871960925676 N/A Mini vortexer Lab 1 2-375973 N/A Waterbath Lab 10 304N0010 N/A Waterbath Lab 1 408N0133 N/A WATERBATH Lab 6 208N0854 N/A TUBE FUSER Lab 5A RW242/Ver. 2.5 N/A Oxygen Generator Rock Road none 1,658 Labscale TFF System WR Lab 7 P4BN3896006 1,599 30L Atmospheric Single Wall Tank Pilot Plant 362 6072 2,108 Fabricate cart for viral concentration PP Rm 362 N/A 2,156 Labscale TFF System -115V Lab 7 P4PN4076018 1,833 Keofit Sample Valve, Biostat-see sys 95 WR LAB 5a Room 135 01010/97, 01008/97 1,219 C-15 Biostat Fermenter WR LAB 6 Room 135B 04082/01 1,237 C-15 Biostat Fermenter WR LAB 6 Room 135B 04070/01 1,238 C-15 Biostat Fermenter WR LAB 6 Room 135B 04055/01 1,752 B. Braun - (2) BioStat C 15L w 25mm DO WR LAB 6 0 1,001 Zeiss trinocular microscope Lab 6 0 2,234 Kodak GEL Logic 100 system (Option B) WR Lab 9 061505-001 1,166 Frac 950 Fraction Collector Lab 2 code # 18-6083-00 1,319 Freezer 201 Witmer 1,320 Freezer 201 Witmer
Page 4 of 6 EXHIBIT B-1 WITMER ROAD PROPERTY - EXCLUDED ASSETS
FAS EQUIPMENT FAS SYSTEM # TAG # TAG # ACQ DATE VENDOR - -------- ----------------- ------- ---------- --------------------------------- 1,317 00432 10/29/02 VWR Scientific 1,318 00433 10/29/02 VWR Scientific 1,443 00670 5/30/2003 Wave Biotech 1,346 00710 11/12/2002 Cole-Parmer Instrument 1,707 01198 5/31/2004 Millipore 1,890 01201 4/23/2004 Amersham Biosciences Corp 1,891 01202 4/23/2004 Amersham Biosciences Corp 1,893 01205 4/23/2004 Amersham Biosciences Corp 1,685 01238 4/30/2004 Fisher Scientific 2,162 01409 1/31/2005 APV 2,186 01422 4/28/2005 Agilent Technologies 2,199 01426 5/26/2005 Amersham Biosciences Copr 2,242 01455 6/26/2006 BioTek 1,094 1094NT 12/20/2001 Workplace Environments 1,254 1254NT 6/30/2002 PGI 1,264 1264NT 7/31/2002 PGI 1,551 1551NT 8/31/2003 Transamerican 1,653 1653NT 1/31/2004 TransAmerican 1,940 1940NT 7/31/2004 Beckman Coulter 1,941 1941NT 7/31/2004 Beckman Coulter 2,157 2157TBD 12/31/2004 New Brunswick Scientific 529 529NT N/A INVITROGEN N/A MILLIPORE N/A N/A N/A Fotodyne N/A HARTMANN & BRAUN N/A INDCO N/A OHAUS CHAMP II N/A CORUING N/A MASTER FLEX N/A CORNING N/A LAB LINE N/A THERMO N/A INVITROGEN N/A MILLIPORE FAS SYSTEM # DESCRIPTION LOCATION SERIAL NUMBER - -------- ---------------------------------------------------------------- ------------------- ------------------- 1,317 Refrigerator 201 Witmer 1,318 Refrigerator 201 Witmer 1,443 Hot Lips Tube Sealer Lab 5A 0043.0303.SLR 1,346 Servodyne high speed, low torque mixer Lab 6 K02005043 1,707 XX42PMini Pellicon 2 mini holder WR Lab 3 N/A 1,890 Akta Purifier 100-see sys 1680, 1891 WR Lab 2 1,891 Akta Purifier 100-see sys 1680, 1890 WR LAB 4 1,893 Akta Purifier 100-see sys 1681, 1892 WR Lab 3 1,685 Eppendorf 5810 R centrifuge w/swing buc Lab 4 - Rm 132 9946 2,162 APV 1000 Lab Homogenizer Lab 2 73888Outp 2,186 1100 Refractive index detector Lab 4 CN43801849 2,199 AKTA explorer P960 sample pump Lab 2 (inside #320) 0 2,242 Precision XS Microplate Sample Processor w/ 1 +8 channel pipette Lab 10-WR 199383 1,094 Furniture for Business Development-now in eng trailer 0 1,254 Renovation of trade booth 0 1,264 Renovation of Trade Booth 0 1,551 Modular office furniture for engineering trailer N/A N/A 1,653 Modular Office Furniture for Engineering Trailer Engineering Trailer N/A 1,940 Upgrade of HPLC from stainless to PEEK 0 1,941 Upgrade of HPLC from stainless to PEEK 0 2,157 150L Bioreactor Skid 0 529 Finnigan Corporation-part of asset# 522 LCQ system #N/A Freezer 201 Witmer Freezer 201 Witmer N/A ELECTROPHORESIS STATION Lab 2 #N/A N/A FILTER HOUSING, 50mm FLAT SHEET Lab 2 #N/A N/A WATER BATHS (qty 2) Lab 2 #N/A Cuno Filter Housings (QTY 2) Lab 2 N/A WATER BATH Lab 3 #N/A N/A Camera for Gels Lab 4 N/A GAS ANALYZER Lab 5 #N/A N/A MIXER Lab 5 #N/A N/A SCALE Lab 5 #N/A N/A pH METER Lab 5A #N/A N/A PUMP Lab 5A #N/A N/A HOT PLATE Lab 6 #N/A N/A ROTATOR Lab 6 #N/A N/A SPECTROPHOTOMETER Lab 6 #N/A N/A ELECTROPHORESIS STATION Lab 7 #N/A N/A TFF UNIT Lab 7 #N/A
Page 5 of 6 EXHIBIT B-1 WITMER ROAD PROPERTY - EXCLUDED ASSETS
FAS EQUIPMENT FAS SYSTEM # TAG # TAG # ACQ DATE VENDOR - -------- ----------------- ------- ---------- --------------------------------- FAS SYSTEM # DESCRIPTION LOCATION SERIAL NUMBER - -------- ---------------------------------------------------------------- ------------------- -------------------
Chemicals and biologicals owned by Neose including, but not limited to, all raw materials, intermediate compounds, finished goods, and equipment stored in warehouses, cold rooms, freezers, refrigerators, incubators, cryovats (except for any items stored by Auxilium) Materials subject to, or covered by, intellectual property that is owned by, licensed to, or controlled by Neose All equipment, materials, and supplies purchased by Neose after July 1, 2006 All IT Equipment (including, but not limited to hardware, software, communications equipment, printers, and copiers) except for such assets specifically identified as Included Assets on Exhibit B Books, records and periodicals, including those on or in file cabinets, hanging file bins, bookshelves, bookcases, and high density storage Binders, lab notebooks, equipment logbooks, and other documentation not specifically identified as Included Assets on Exhibit B Back-up tapes Drawings that are not specific to the Property or Included Assets Contents of closets (except for janitorial supplies and cleaning equipment) Spare parts for excluded assets Wall hangings Office supplies, shredder bins, and portable heaters Preprinted documents and signs that include Neose's name, logo, or other identifying information Non-swivel chairs in the main conference room Personal effects of Neose employees Page 6 of 6 102 WITMER ROAD, HORSHAM, PA EXHIBIT C PROPERTY DOCUMENTS The following Property Documents have been provided to Buyer: 1. Drawings, Plans and similar documents 1.1 American Land Title Association (ALTA) Survey dated September 5, 2003. 1.2 HVAC plan for offices and laboratories 1.3 Site Plan dated September 27, 2001 1.4 Lab 5 Upgrade plan (1999) 1.5 Pilot Plant Renovation plan (2001) 1.6 Pilot Plant Upgrade plan (2003) 1.7 Pilot Plant Upgrade plan (2004) 1.8 Lab 5 Upgrade plan (2005) 2. Permits and Approvals 2.1 Occupancy Permit - File number 000430902 2.2 Occupancy Permit - File number 000396011 2.3 Occupancy Permit - File number 000392749 2.4 Occupancy Permit - File number 264719 2.5 Occupancy Permit - File number 299819 2.6 Certificate of Occupancy dated September 4, 2003 - Permit number 23645 2.7 Certificate of Occupancy dated January 31, 2002 - Permit number 22149 2.8 Certificate of Occupancy dated September 17, 2001 - Permit number 21868 2.9 Certificate of Occupancy dated July 19, 2001 - Permit number 21703 2.10 Electrical approval dated February 23, 1997 2.11 Plumbing permit dated January 14, 1997 - Permit number 8184 2.12 Letter from the law offices of Grim, Biehn & Thatcher dated December 20, 2001 indicating that The Township of Horsham (the "Township") had granted conditional preliminary approval of Neose Technologies, Inc.'s ("Neose") land development plan 3. Financial Information related to 102 Witmer Road 3.1 Listing of insurance coverage for 102 Witmer Road 3.2 A copy of the tax bill issued for the prior 3 years for real estate taxes 3.3 Operating expense budget for 102 Witmer Road 3.4 Complete Appraisal Self-Contained Report dated December 12, 2003 3.5 Summary Complete Appraisal dated March 20, 1997 4. Documents related to Land Use (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 37 102 WITMER ROAD, HORSHAM, PA 4.1 Agreement To Accept Conditions dated January 29, 2002 by and between Neose and the Township (as filed) 4.2 Easement Agreement dated January 24, 2002 by and between Neose and Liberty Property Limited Partnership 4.3 Opinion and Order of June 11, 2001 of the Zoning Hearing Board of Horsham Township, Montgomery County, PA 4.4 Declaration of Use Restriction Covenant dated December 11, 2001 (as filed) 4.5 Agreement To Accept Conditions dated December 21, 2001 by and between Neose and the Township (as filed) 4.6 Declaration of Covenants and restrictions dated March 13, 1997 (effective March 20, 1997) by and between Neose and Pennsylvania Business Campus Delaware, Inc. ("PBCD") 5. Transaction Documents related to Neose's purchase of 102 Witmer Road 5.1 Deed dated March 20, 1997 (as filed) 5.2 Agreement for the Purchase and Sale of Real Property dated March 14, 1997 by and between Neose and PBCD 5.3 Bill of Sale dated March 20, 1997 5.4 General Assignment dated March 20, 1997 by and between Neose and PBCD 6. Documents related to Environmental Matters 6.1 Environmental Status Summary Memo dated July 17, 2006 6.2 Phase I Environmental Site Audit Dated January 8, 1997 6.3 Completed Phase I Audit questionnaire (completed for 8.2, above) 7. Current Service Contracts related to 102 Witmer Road with the following vendors: 7.1 Airgas East 7.2 Alfa Laval 7.3 Applied Control Engineering 7.4 Artic Coolers 7.5 AT Chadwick Service Company 7.6 Brickman Group 7.7 Dionex Corp. 7.8 Integrated Service Solutions 7.9 JC Ehrlich & Co 7.10 Johnson Controls 7.11 Neu-Ion 8. Other documents provided directly to Buyer 8.1 Organizational documents of Neose (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered registered trademarks of Alexandria Real Estate Equities, Inc. 38 102 WITMER ROAD, HORSHAM, PA 8.2 Commitment for Title Insurance from Lawyers Title Insurance Company 9. Documents provided to agents or other representatives of Buyer 9.1 Copies of July & August 2006 energy bills for Property 9.2 Written summary of renovations to the Property 9.3 Copy of air emissions permit issued by the PA Department of Environmental Protection ("PA DEP") 9.4 PA DEP EPA number and status as a Small Quantity Generator 9.5 Inventory of chemicals on the Property 9.6 Chemical hygiene plan 9.7 Radiation safety manual 9.8 Documentation related to radiation decommissioning at the Property 9.9 Copies of monthly reports to water authority regarding waste/effluent pH 9.10 Copies of water authority permits 9.11 Samples of waste manifest 9.12 Current floor and site plan 9.13 Summary of MSDS program procedures 9.14 Neose environmental philosophy & policy document 9.15 Names and addresses of waste haulers (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 39 102 WITMER ROAD, HORSHAM, PA EXHIBIT D PROPERTY QUESTIONNAIRE Attached (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 40 Property Questionnaire 102 WITMER ROAD, HORSHAM, PA 19044 - Page 1 FORM LAST REVISED 12/05/0 ALEXANDRIA REAL ESTATE EQUITIES, INC. PROPERTY QUESTIONNAIRE Name of Property: Neose Technologies, 102 Witmer Road, Horsham. PA, 19044 (the "PROPERTY") THIS QUESTIONNAIRE SHOULD BE COMPLETED BY THE PROPERTY MANAGER OR THE MOST SENIOR MANAGEMENT PERSON OF THE COMPANY THAT IS FAMILIAR WITH THE DETAILS OF THE PROPERTY AND ITS OPERATION. 1. Which of the following best describes the Property? (Check more than one box if applicable.) [ ] Scientific research and development laboratory facility [ ] Assembly, distribution, pilot plant, or full-scale manufacturing facility [ ] Headquarters or administrative offices [ ] Build-to-suit or retrofit project [ ] Warehouse facility [ ] Raw land [ ] Other (please describe): 2. How many different tenants currently lease space at the Property? [X] 0-5 [ ] 6-10 [ ] 11-15 [ ] More than 15 N/A - PROPERTY IS OCCUPIED FULLY BY OWNER (C) All Rights Reserved -- Alexandria Real Estate Equities, Inc. 1999 CONFIDENTIAL - DO NOT COPY OR DISTRIBUTE 102 WITMER ROAD, HORSHAM, PA 19044 - Page 2 3. a. Does any lease in connection with the Property provide for any rental payments based upon the net income or profits of the tenant(1) or that are contingent in any respect other than rental payments that vary (i) as a percentage or percentages of the tenant's gross receipts or sales, or (ii) because of "escalation clauses"? If yes, please explain. [ ] YES [X] NO Explain: N/A - PROPERTY IS OCCUPIED FULLY BY OWNER b. Do the terms of any lease contain "escalation clauses" other than standard escalation provisions requiring adjustments in the amount of rent due based upon changes in the consumer price index or in the costs of the Owner for insurance, property taxes or maintenance expenses? If yes, please list all such items that would potentially require any adjustment under any escalation clause. [ ] YES [X] NO List: N/A - PROPERTY IS OCCUPIED FULLY BY OWNER c. In connection with the lease of the Property, is any tenant entitled to receive any economic incentives (e.g., "free" or reduced rent, tenant improvement allowances, etc.)' If yes, please explain. [ ] YES [X] NO Explain: N/A - PROPERTY IS OCCUPIED FULLY BY OWNER d. Are the terms of all lease payments and formulas typical and customary for properties of a character and quality similar to the Property that are located in the same geographic market, and do these provisions conform with normal business practice? If no, please explain which provisions are not typical or customary, or do not conform with normal business practice. [X] YES NO [ ] Explain: N/A - PROPERTY IS OCCUPIED FULLY BY OWNER - ---------- (1) Responses to any questions about leases or tenants should take into account, where applicable, any subleases and sub-tenants. (C) All Rights Reserved -- Alexandria Real Estate Equities, Inc. 1999 CONFIDENTIAL - DO NOT COPY OR DISTRIBUTE 102 WITMER ROAD, HORSHAM, PA 19044 - Page 3 e. Which of the following best describes the percentage of the leases that are "triple net"? [X] ALL [ ] MOST [ ] SOME [ ] NONE N/A - PROPERTY IS OCCUPIED FULLY BY OWNER 4. a. Is the percentage of the total rent attributable to personal property more than 15 percent of the total rent from any lease? [ ] YES [ ] NO N/A - PROPERTY IS OCCUPIED FULLY BY OWNER b. Are any temperature-controlled or other specialized rooms located at the Property (e.g., "cold rooms", "warm rooms", or "clean rooms")? If yes, please list the approximate number of such items located in each unit and/or floor. [ ] YES [ ] NO List: four cold rooms (three at 2-8 C, one at -20 C), entire pilot plant consists of clean rooms c. Do any of the units at the Property contain any individual air conditioning, heating, refrigeration, or freezer units that are owned or leased by the Owner, other than centralized HVAC or any specialized rooms described in question 4(b)? If yes, please describe. [ ] YES [ ] NO Explain: Miscellaneous refrigerators and freezers are located in a number of rooms/laboratories d. Do any of the units at the Property contain any movable lab benches or tables, furniture (e.g., desks, chairs or lamps), laboratory equipment (e.g., microscopes, centrifuges or glassware), boilers, air compressors, deionizing apparatus, reverse osmosis apparatus, vacuum pumps, glassware washers, oven dryers, animal washers, animal caging, incinerators, or other significant items of specialized equipment that is owned or leased by the Owner? If yes, please attach a list of such items (if available). [ ] YES [ ] NO See equipment list attached 5. a. Does any entity other than the Owner manage the Property or any portion of the Property (the "MANAGER")? if yes, please identify the Manager; [ ] YES [ ] NO - PROPERTY IS OCCUPIED FULLY BY OWNER (C) All Rights Reserved -- Alexandria Real Estate Equities, Inc. 1999 CONFIDENTIAL - DO NOT COPY OR DISTRIBUTE 102 WITMER ROAD, HORSHAM, PA 19044 - Page 4 Name of Manager: ______________________ b. If the answer to question 5(a) is yes, are there any arrangements pursuant to which the Manager refunds, rebates or otherwise provides any credit with respect to its fee relating to the Property? If yes, please explain. [ ] YES [ ] NO [ ] N/A Explain: c. Does the Owner employ any on-site personnel at the Property? If yes, please name such person(s) and describe their general duties. [ ] YES [X] NO Explain: PROPERTY IS OCCUPIED FULLY BY OWNER 6. a. Are all services provided to tenants of the Property by the Owner or the Manager (if applicable) typical and customary for properties of a character and quality similar to the Property that are located in the same geographic market? If no, please describe which services or arrangements are not typical and customary. [X] YES [ ] NO Explain: N/A - PROPERTY IS OCCUPIED FULLY BY OWNER b. Are you aware of any other services provided to tenants by any person hired by the Owner or the Manager that are not typical and customary for properties of a character and quality similar to the Property that are located in the same geographic market? If yes, please explain. [ ] YES [X] NO Explain: N/A - PROPERTY IS OCCUPIED FULLY BY OWNER 7. a. Are there any arrangements for the Owner or the Manager to provide architectural, construction or engineering services to any tenant at the Property (e.g. "building-out" the Property as part of lease inducements)? [ ] YES [X] NO N/A - PROPERTY IS OCCUPIED FULLY BY OWNER (C) All Rights Reserved -- Alexandria Real Estate Equities, Inc. 1999 CONFIDENTIAL - DO NOT COPY OR DISTRIBUTE 102 WITMER ROAD, HORSHAM, PA 19044 - Page 5 IF THE ANSWER TO QUESTION 7(A) IS NO, PLEASE SKIP TO QUESTION 8; OTHERWISE, PLEASE ANSWER QUESTIONS 7(B) THROUGH 7(D). b. Are such arrangements only provided as an inducement to the tenant to enter into or extend a lease? [ ] YES [ ] NO c. Are such arrangements typical and customary for properties of a character and quality similar to the Property that are located in the same geographic market? If no, please explain which arrangements are not typical and customary. [ ] YES [ ] NO Explain: d. Does the Owner or the Manager expect to derive any income (e.g., development fees) from such arrangements? If yes, please describe. [ ] YES [ ] NO Explain: e. Do any such arrangements provide for the purchase, funding, or installation by the Owner of any significant items of property which could be deemed to constitute "personal property"? If yes, please describe any such items of property. [ ] YES [ ] NO Explain: 8. a. Please check any utility services that the Owner or the Manager directly or indirectly plays any role in providing to tenants at the Property: [ ] Electric [ ] Gas [ ] Water [ ] Telephone [X] Heat/Air cond. [ ] Sewage [ ] Facsimile [ ] Cable TV [ ] Other: (Please list) T1 Lines NOTE - THE SERVICES CHECKED ABOVE ARE AVAILABLE AT THE PROPERTY, THOUGH OWNER MAY NOT UTILIZE ALL OF THOSE CHECKED. b. Are all such utility services typical and customary for properties of a character and quality similar to the Property that are located in the same geographic market? If no, please list any utility services that are not typical and customary, (C) All Rights Reserved -- Alexandria Real Estate Equities, Inc. 1999 CONFIDENTIAL - DO NOT COPY OR DISTRIBUTE 102 WITMER ROAD, HORSHAM, PA 19044 - Page 6 [ ] YES [ ] NO [ ] N/A List: c. Are tenants charged, either as a separate recoverable amount or as part of common area maintenance costs, for all such utility services? If no, please explain which services are provided at no charge and whether this is a typical and customar practice for properties of a quality and character similar to the Property that are local in the same geographic market. [ ] YES [X] NO Explain: N/A - PROPERTY IS OCCUPIED FULLY BY OWNER d. Are individual units separately metered to measure utility usage, with tenants charged by the Owner or the Manager, as appropriate, in proportion to usage? If no please briefly explain how charges for utilities are determined and allocated among the various tenants (e.g., pro-rata based on square footage, etc.). [ ] YES [X] NO [ ] N/A Explain: e. If any tenant is charged by the Owner or the Manager for any utility service, the tenant billed without any fee, income, profit or other markup over the cost? If no, please explain. [ ] YES [ ] NO [ ] N/A Explain: PROPERTY IS OCCUPIED FULLY BY OWNER f. Does the Owner or the Manager derive any income from any utility provider a the Property? If yes, please explain. [ ] YES [X] NO [ ] N/A Explain: PROPERTY IS OCCUPIED FULLY BY OWNER a. Are pay telephones and vending (e.g., soda, cigarette, candy, etc.) mach provided at the Property by the Owner, by the Manager, or by third-party suppliers? (Check more than one response if appropriate.) (C) All Rights Reserved -- Alexandria Real Estate Equities, Inc. 1999 CONFIDENTIAL - DO NOT COPY OR DISTRIBUTE 102 WITMER ROAD, HORSHAM, PA 19044 - Page 7 [ ] OWNER [ ] MANAGER [ ] THIRD PARTY [ ] N/A Explain: Third party provides vending machine currently b. If pay telephones or vending machines are provided or operated by a third-party supplier, does that person pay the Owner or the Manager any rent, fee, or any other amount? [ ] YES [ ] NO [ ] N/A c. If the answer to question 9(b) is yes, is such amount fixed or based upon a percentage of gross receipts? If it is not fixed or based upon a percentage of gross receipts, please explain. [ ] YES [ ] NO [ ] N/A Explain: 10. a. Please check any of the following that describes the parking provided at or with respect to the Property. (Check more than one box if applicable.) [ ] Open lot / no gated entry [ ] Open lot / gated entry [ ] Single level parking garage [ ] Multi-tier parking garage [ ] Specific spaces (or group of spaces) reserved or preferential parking for tenant(s) or their employees [ ] Cashier/parking lot attendant on duty [ ] Valet parking available [ ] Security guard on duty b. Is all parking at or with respect to the Property available to tenants (or to their or employees or guests) without separate charge and only on an unreserved basis (i.e., no tenant is assigned particular space(s)), other than valet parking services (as described in response to question 11(c) below) or reserved parking for handicapped persons? If no, please explain the parking arrangements between the Owner and the tenants. [X] YES [ ] NO Explain: N/A - PROPERTY IS OCCUPIED FULLY BY OWNER c. Are there any attendants or are any additional related services provided (e.g., valet parking, security, car wash)? If yes, please describe the functions of such (C) All Rights Reserved -- Alexandria Real Estate Equities, Inc. 1999 CONFIDENTIAL - DO NOT COPY OR DISTRIBUTE 102 WITMER ROAD, HORSHAM, PA 19044 - Page 8 person(s) and the nature of such services (including any services indicated in respons to question 10(a)). In addition, please indicate whether any such services are typical and customary for properties of a similar character and quality as the Property that are located in the same geographic market. [ ] YES [ ] NO Explain: d. For those persons who pay to park at the Property (including in connection with any valet parking services), please indicate the period of time, if any, for which their parking privileges are generally valid (e.g., hourly, daily, monthly, etc.). Duration: N/A e. Is there a person or entity (an "Operator") that either operates the parking facilities or provides related services (e.g., valet services)? If yes, please identify the Operator and attach any separate agreement evidencing those arrangements. [ ] YES [ ] NO Operator(s): ___________________ IF THE ANSWER TO QUESTION 10(E) IS NO, PLEASE SKIP TO QUESTION 11; OTHERWISE, PLEASE ANSWER QUESTIONS 10(F) THROUGH 10(H). f. Please briefly explain the manner in which each Operator is compensated for it role in providing parking (e.g., fixed fee, percentage of gross parking revenues, etc.). Explain: g. Does either of the Owner or the Manager bear any portion of any Operator's costs or expenses? If yes, please explain the arrangement. [ ] YES [ ] NO [ ] N/A Explain: (C) All Rights Reserved -- Alexandria Real Estate Equities, Inc. 1999 CONFIDENTIAL - DO NOT COPY OR DISTRIBUTE 102 WITMER ROAD, HORSHAM, PA 19044 - Page 9 h. Does either of the Owner or the Manager derive any income from the Opera from any parking charges? If yes, please explain. [ ] YES [ ] NO [ ] N/A Explain: 11. Does the Owner or the Manager directly or indirectly play any role in providing security services to individual tenants? Answer no if the only involvement of these entities in providing security services is with respect to the Property as a whole or its common areas, and not for individual units or tenants. [ ] YES [X] NO [ ] PROPERTY IS OCCUPIED FULLY BY OWNER 12. a. Does the Owner or the Manager directly or indirectly play any role in providing janitorial services to individual tenants? Answer no if the only involvement these entities in providing janitorial services is with respect to the Property as a whole its common areas, and not for individual units or tenants. [ ] YES [X] NO [ ] PROPERTY IS OCCUPIED FULLY BY OWNER IF THE ANSWER TO QUESTION 12(a) IS NO, PLEASE SKIP TO QUESTION 13; OTHERWISE, PLEASE ANSWER QUESTIONS 12(b) THROUGH 12(d). b. Is the provision of such service typical and customary for properties of a character and quality similar to the Property that are located in the same geographic market? If no, please explain. [ ] YES [ ] NO Explain: c. Does the Owner or the Manager bear any portion of the cost or expense of providing janitorial services to tenants? If yes, please explain. [ ] YES [ ] NO Explain: (C) All Rights Reserved -- Alexandria Real Estate Equities, Inc. 1999 CONFIDENTIAL - DO NOT COPY OR DISTRIBUTE 102 WITMER ROAD, HORSHAM, PA 19044 - Page 10 d. Does the Owner or the Manager derive any income in connection with the janitorial services provided to tenants? If yes, please explain. [ ] YES [ ] NO Explain: e. Are tenants directly or indirectly charged for any janitorial services provided at the Property? If yes, please briefly explain the manner in which these charges are determined (e.g., pro-rata based on relative square footage). [ ] YES [ ] NO Explain: 13. a. Is the actual maintenance of the Property's common areas performed by employees of the Owner, the Manager, or an unrelated third-party? (Check more than one response if appropriate.) [ ] OWNER [ ] MANAGER [ ] THIRD-PARTY NO COMMON AREA, PROPERTY IS OCCUPIED FULLY BY OWNER b. Does the Owner or the Manager bear any portion of the cost of common area maintenance? If yes, please explain. [ ] YES [X] NO Explain: N/A - NO COMMON AREA, PROPERTY IS OCCUPIED FULLY BY OWNER c. Are tenants charged for common area maintenance? If yes, please explain the manner in which these charges are determined (e.g., pro-rata based on relative square footage). [ ] YES [X] NO N/A - NO COMMON AREA, PROPERTY IS OCCUPIED FULLY BY OWNER d. Are the services and arrangements with respect to the Property's common area maintenance typical and customary for properties of a character and quality similar to the Property that are located in the same geographic market? If no, please explain. [X] YES [ ] NO Explain: N/A - NO COMMON AREA, PROPERTY IS OCCUPIED FULLY BY OWNER (C) All Rights Reserved -- Alexandria Real Estate Equities, Inc. 1999 CONFIDENTIAL - DO NOT COPY OR DISTRIBUTE 102 WITMER ROAD, HORSHAM, PA 19044 - Page 11 14. Are any tenants charged by the Owner or the Manager any fee or other amount that is not typically and customarily charged in connection with the rental of properties of a character and quality similar to the Property in the same geographic market?(2) If yes, please explain. [ ] YES [X] NO [ ] N/A Explain: PROPERTY IS OCCUPIED FULLY BY OWNER 15. a. Does the Owner or the Manager render any services to any tenant (or to employees of any tenant) other than as disclosed above in this questionnaire (e.g., glassware cleaning, electron microscopy, animal care or storage, information services (e.g., Internet or LAN connections), telecommunication services (e.g., voice mail), day care, babysitters, food services, etc.)? [ ] YES [X] NO Explain: N/A - PROPERTY IS OCCUPIED FULLY BY OWNER b. Are all of the services described in the response to question 15(a) above typical and customary for properties of a character and quality similar to the Property that are located in the same geographic market? If no, please describe which services or amenities are not typical and customary. [X] YES [ ] NO [ ] N/A Explain: PROPERTY IS OCCUPIED FULLY BY OWNER c. Does the Owner or the Manager directly or indirectly derive any income, bear a costs or expenses, or employ any persons in connection with any atypical or non-customary services indicated in the response to question 15(b) above? If yes, please explain. [ ] YES [X] NO [ ] N/A Explain: N/A - PROPERTY IS OCCUPIED FULLY BY OWNER - ---------- (2) Typical and customary fees might include, in some markets, late payment fees, subleasing fees, application fees, credit check fees, release fees, etc. (C) All Rights Reserved -- Alexandria Real Estate Equities, Inc. 1999 CONFIDENTIAL - DO NOT COPY OR DISTRIBUTE 102 WITMER ROAD, HORSHAM, PA 19044 - Page 12 16. Is any space at the Property leased to any non-commercial tenants (i.e., residential tenants)? [ ] YES [ ] NO 17. a. Are any services rendered to any tenant by third-party suppliers hired by the Owner or the Manager, other than as previously disclosed in this questionnaire? [ ] YES [X] NO N/A - PROPERTY IS OCCUPIED FULLY BY OWNER b. if the answer to question 17(a) above is yes, are all of those services typical an customary for properties of a character and quality similar to the Property that are located in the same geographic market? If not, please describe which services are not typical and customary. [ ] YES [ ] NO [ ] N/A Explain: PROPERTY IS OCCUPIED FULLY BY OWNER Does any of the Owner, an Affiliate or the Manager share in any income or compensation received by any third-party service provider with respect to the rendering of services to any tenant, other than as previously disclosed in this questionnaire? If yes, please explain the arrangements. [ ] YES [X] NO [ ] N/A Explain: PROPERTY IS OCCUPIED FULLY BY OWNER 18. Does the Company or the Manager engage in any revenue-generating activities in connection with the Property not mentioned previously in this questionnaire (other than the rental of real property or the investment of excess cash)? [ ] YES [ ] NO Explain: 19. a. Does the Owner separately lease any storage space at the Property? [ ] YES [ ] NO (C) All Rights Reserved -- Alexandria Real Estate Equities, Inc. 1999 CONFIDENTIAL - DO NOT COPY OR DISTRIBUTE 102 WITMER ROAD, HORSHAM, PA 19044 - Page 13 b. if the answer to question 19(a) is yes, is such storage space a temperature- controlled or other specialized room described in question 4(b) (e.g., freezer warehouse)? [ ] YES [ ] NO Explain: ---------------------------------------- Name: ---------------------------------- Title: --------------------------------- , 200 - -------------- - ---------------------------------------- Signature SEE ATTACHED. PREPARED BY JIM WHITE & REVIEWED BY LARRY DIAMOND 7/25/06 (C) All Rights Reserved -- Alexandria Real Estate Equities, Inc. 1999 CONFIDENTIAL - DO NOT COPY OR DISTRIBUTE ALEXANDRIA REAL ESTATE EQUITIES, INC. NEW PROPERTY REPORTING FORM Property Name: Neose Technologies, 102 Witmer Road, Horsham, PA Address: 102 Witmer Road, Horsham, PA 19044 Property Type (i.e., industrial, retail, office, warehouse, etc.): office/lab Owned or Leased: Owned Operational Activities of Tenants: LAB & MANUFACTURING BUILDING DESCRIPTION & CONSTRUCTION (SUBMIT SEPARATE SHEETS FOR EACH BUILDING) Building Construction: CMU/steel on slab Roof Construction: Membrane Number of Buildings: 1 Land Area: 4.1 acres Stories Above Grade: 1 Building Square Feet (gross): 50,000 Stories Below Grade: 0 Building Square Feet (rentable): 50,000 Year Built / Refurbished: approx. 1975 Parking Square Feet: NOT CALCULATED Date Acquired: 9/06 No. of Parking Spaces: 109 Date of Seismic Upgrade: N/A No. of Elevators/Escalators: 0 Boiler / Machinery Exposure: ___________________________________________________________________
LIFE SAFETY & SECURITY Percent of Building Sprinklered: 100% Smoke Detection: Yes Central Alarm: Yes Fire Detection: Yes Fire / Life Safety System Notes: All up to code. Fire Department pre-planning visits complete. Security Provisions Access controlled 24/7/365, key card access or access through reception/receiving c Burglary system detects door break, glass breaks, specific door openings during armed Strategically located alarm 'panic button' also in place. VALUES Building: ___ ) Contents: $-- ) T.B.D. Rent: $-- ) Total: $-- ) Submitted by: Name: Date: ------------------------------- ---------------------------------- Title: ------------------------------ SEE ATTACHED. PREPARED BY JIM WHITE & REVIEWED BY LARRY DIAMOND 7/25/06 Page 1 102 WITMER ROAD, HORSHAM, PA EXHIBIT E SURVEYOR'S CERTIFICATE To: ARE-PA REGION NO. 6, LLC, a Delaware limited liability company, its successors and assigns, and Chicago Title Insurance Company. This is to certify that this map or plat and the survey on which it is based were made on the date shown below of the premises described in Chicago Title Insurance Company's title commitment dated as of June 1, 2006, issued under Order No. 810600251, (i) in accordance with the "Minimum Standard Detail Requirements for ALTA/ACSM Land Title Surveys," jointly established and adopted by ALTA and NSPS in 2005, as defined therein, and includes Items 2, 3, 4, 6, 7(a), 7(b)(1), 7(c), 8, 9, 10, 11(a), 13, 14, 16, 17 and 18 of Table A thereof. Pursuant to the Accuracy Standards for ALTA/ACSM Land Title Surveys as adopted by ALTA and NSPS and in effect on the date of this certification, the undersigned further certifies that in my professional opinion as a land surveyor registered in the Commonwealth of Pennsylvania, the Relative Positional Accuracy of this survey does not exceed that which is specified therein. This survey was also made in accordance with the Commonwealth of Pennsylvania Minimum Standards of Practice for Land Surveyors. The subject property contains _______________ square feet or _______________ acres, is located in a zoning district classification of _______________, and contains _______________ regular parking spaces and _______________ handicapped parking spaces, totaling _______________ regular and handicapped parking spaces. The survey correctly shows the zone designation of any area shown as being within a Special Flood Hazard Area according to current Federal Emergency Management Agency Maps which make up a part of the National Flood Insurance Administration Report; Community No. _______________, Panel No._______________ dated _______________ ___, 2006. The subject property has ingress and egress to and from _______________ which is a paved, public right-of-way. The street address of the subject property is 102 Witmer Road, Horsham, Pennsylvania. [Surveyor's Name] By Date: ---------------------------------- ---------------------------------- Registered Land Surveyor No. ------- ------------ Date of Survey: -------------- Date of Last Revision: -------------- (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 41 102 WITMER ROAD, HORSHAM, PA EXHIBIT F DEED PREPARED BY: DIANA LIU, ESQUIRE WOLF, BLOCK, SCHORR AND SOLIS-COHEN, LLP 1650 ARCH STREET, 22ND FLOOR PHILADELPHIA, PA 19103 RECORD AND RETURN TO: KEVIN L. SHEPHERD, ESQUIRE VENABLE LLP SUITE 1800, TWO HOPKINS PLAZA BALTIMORE, MD 21201-2978 TAX PARCEL NO. _______________ DEED THIS INDENTURE made this _______________ day of September, 2006, between NEOSE TECHNOLOGIES, INC., a Delaware corporation ("GRANTOR"), and ARE-PA REGION NO. 6, LLC, a Delaware limited liability company ("GRANTEE"). WITNESSETH, GRANTOR, for and in consideration of the sum of Twenty-One Million Fifty Thousand Dollars ($21,050,000) lawful money of the United States, unto Grantor well and truly paid by GRANTEE, at and before the sealing and delivery of these presents, the receipt whereof is hereby acknowledged, has conveyed, granted, bargained, sold, released, and confirmed, and by these presents does convey, grant, bargain, sell, release, and confirm unto GRANTEE, its successors and assigns: ALL THAT CERTAIN lot or piece of ground described on Schedule A attached hereto. BEING THE SAME premises that the Pennsylvania Business Campus Delaware, Inc., a Delaware corporation, by Deed dated March 20, 1997, and recorded March 25, 1997 in the Office for the Recording of Deeds, in and for the County of Montgomery, Commonwealth of Pennsylvania in Deed Book 5180 page 1582, granted and conveyed unto Grantor, in fee. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 42 102 WITMER ROAD, HORSHAM, PA TOGETHER with all and singular the buildings, improvements, streets, alleys, passages, ways, waters, water-courses, rights, liberties, privileges, hereditaments, and appurtenances whatsoever thereunto belonging, or in any wise appertaining, and the reversions and remainders, rents, issues, and profits thereof; and all the estate, right, title, interest, property, claim, and demand whatsoever, of GRANTOR, in law, equity, or otherwise, of, in, and to the same. TO HAVE AND TO HOLD the said lot or piece of ground above described, with the buildings and improvements thereon erected, hereditaments, and premises hereby granted, or mentioned and intended so to be, with the appurtenances unto GRANTEE, its successors and assigns, to and for the only proper use and behoof of GRANTEE, its successors and assigns, forever. AND GRANTOR, for itself and its successors and assigns, does by these presents, covenant, grant, and agree, to and with GRANTEE, its successors and assigns, that Grantor and its successors and assigns, all and singular the hereditaments and premises herein above described and granted, or mentioned and intended so to be, with the appurtenances, unto GRANTEE, its successors and assigns, against Grantor, its successors and assigns, and against all and every other person or persons whomsoever lawfully claiming or to claim the same or any part thereof, by, from, or under it, them, or any of them, shall and will WARRANT and forever DEFEND. IN WITNESS WHEREOF, GRANTOR has executed this Deed as a sealed instrument the day and year first above written. NEOSE TECHNOLOGIES, INC., a Delaware corporation By: ------------------------------------ Name: ---------------------------------- Title: ---------------------------------- COMMONWEALTH OF : : SS. COUNTY OF : ON THIS, the _______________ day of _______________, 2006, before me, the undersigned officer, a Notary Public, personally appeared _______________, who acknowledged himself/herself to be the _______________ of Neose Technologies, Inc., a Delaware corporation, and further acknowledged that he/she, as such Officer and being authorized to do so, executed the foregoing instrument as the act and deed of the corporation for the purposes therein contained by signing the name of the corporation by himself/herself as such Officer. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 43 102 WITMER ROAD, HORSHAM, PA IN WITNESS WHEREOF, I hereunto set my hand and official seal. ---------------------------------------- Notary Public The address of the within-named Grantee is: ARE-PA REGION NO. 6, LLC C/O ALEXANDRIA REAL ESTATE EQUITIES, INC. 385 E. COLORADO BLVD., SUITE 299 PASADENA, CALIFORNIA 91101 ATTENTION: CORPORATE SECRETARY RE: 102 WITMER ROAD ---------------------------------------- On Behalf of the Grantee (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 44 102 WITMER ROAD, HORSHAM, PA SCHEDULE A Metes and Bounds description of Unit 30, Block 60A, APN # 36-00-11954-016, lands now or formerly Neose Technologies, Inc., Horsham Township, Montgomery County, Commonwealth of Pennsylvania as described on the ALTA/ACSM Land Title Survey prepared by Control Point Associates, Inc., dated August 8, 2006, File No. CP97002.02 as follows: BEGINNING at a concrete monument along the Northeasterly legal right-of-way of Witmer Road (a.k.a. T-405, 60.00 feet wide right-of-way), at its intersection with the dividing line between Unit 30, Block 60A, APN #36-00-11954-016, Lands now or formerly Neose Technologies, Inc., and Unit 1, Block 60A, APN #36-00-11954-025, Lands now or formerly Liberty Property Limited Partnership, and from said point of beginning running, thence; 1. along the northeasterly legal right-of-way line of Witmer Road, North 23 degrees 42 minutes 10 seconds West, a distance of 376.11 feet to a point, thence; 2. along the dividing line between Unit 30, Block 60A, APN # 36-00-11954-016, and Unit 29, Block 60A, APN # 36-00-11954-007, Lands now or formerly Liberty Property Limited Partnership, North 44 degrees 49 minutes 22 seconds East, a distance of 428.99 feet to a railroad spike, thence; 3. along the dividing line between Unit 30, Block 60A, APN # 36-00-11954-016 and Unit 22, Block 60A, APN # 36-00-10235-052, Lands now or formerly Liberty Property Limited Partnership, South 45 degrees 10 minutes 38 seconds East, a distance of 350.00 feet to a concrete monument; 4. along the dividing line between Unit 30, Block 60A, APN #36-00-11954-016 and Unit 1, Block 60A, APN # 35-00-11954-025, South 44 degrees 49 minutes 22 seconds West, a distance of 566.68 feet to a concrete monument on the northeasterly legal right-of-way of Witmer Road and the point and place of beginning. Containing 174,242 square feet or 4.000 acres, more or less. TOGETHER WITH easements as set forth in Easement Agreement between Liberty Property Limited Partnership, a Pennsylvania limited partnership and Neose Technologies, Inc., a Delaware corporation, dated January 24, 2002 and recorded January 30, 2002 in the Office of the Recorder of Deeds in and for the County of Montgomery, Pennsylvania in Deed Book 5393 at Page 2346. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 45 102 WITMER ROAD, HORSHAM, PA EXHIBIT G SELLER'S CERTIFICATE The undersigned hereby certifies to ARE-PA REGION NO. 6, LLC, a Delaware limited liability company ("BUYER") that, as of the date hereof: 1. all of the representations, covenants and warranties of Neose Technologies, Inc., a Delaware corporation ("SELLER"), made in or pursuant to that certain Purchase and Sale Agreement and Joint Escrow Instructions dated as of September __, 2006 (the "AGREEMENT"), between Seller and Buyer are true, accurate, correct and complete; 2. all conditions to the Closing (as such term is defined in the Agreement) that Seller was to satisfy or perform have been satisfied and performed; and 3. all conditions to the Closing that Buyer was to perform have been satisfied and performed. Dated September ___, 2006 Neose Technologies, Inc., a Delaware corporation By: ------------------------------------ Name: ---------------------------------- Title: --------------------------------- (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 46 102 WITMER ROAD, HORSHAM, PA EXHIBIT H NON-FOREIGN AFFIDAVIT 1. Section 1445 of the Internal Revenue Code of 1986, as amended (the "CODE"), provides that a transferee of a United States real property interest must withhold tax if the transferor is a foreign person. 2. In order to inform ARE-PA REGION NO. 6, LLC, a Delaware limited liability company, and its nominees, designees and assigns (collectively, "TRANSFEREE"), that withholding of tax is not required upon the disposition by Neose Technologies, Inc., a Delaware corporation ("TRANSFEROR"), of the United States real property more particularly described on Exhibit A attached hereto and incorporated herein by reference (the "PROPERTY"), the undersigned Transferor certifies and declares by means of this certification, the following: a. Transferor is not a foreign person, foreign corporation, foreign partnership, foreign trust or foreign estate (as such terms are defined in the Code and the Income Tax Regulations). b. Transferor's federal taxpayer identification number is: 13-3549286. c. Transferor's address is: 102 Witmer Road Horsham Pennsylvania 19044 3. Transferor understands that this certification may be disclosed to the Internal Revenue Service by Transferee and that any false statement contained in this certification may be punished by fine, imprisonment or both. Under penalties of perjury, Transferor declares that it has carefully examined this certification and it is true, correct and complete. Executed this _________ day of September, 2006 at ________________________. TRANSFEROR: NEOSE TECHNOLOGIES, INC. By: ------------------------------------ Name: ---------------------------------- Its: ----------------------------------- (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 47 102 WITMER ROAD, HORSHAM, PA EXHIBIT A LEGAL DESCRIPTION Metes and Bounds description of Unit 30, Block 60A, APN # 36-00-11954-016, lands now or formerly Neose Technologies, Inc., Horsham Township, Montgomery County, Commonwealth of Pennsylvania as described on the ALTA/ACSM Land Title Survey prepared by Control Point Associates, Inc., dated August 8, 2006, File No. CP97002.02 as follows: BEGINNING at a concrete monument along the Northeasterly legal right-of-way of Witmer Road (a.k.a. T-405, 60.00 feet wide right-of-way), at its intersection with the dividing line between Unit 30, Block 60A, APN #36-00-11954-016, Lands now or formerly Neose Technologies, Inc., and Unit 1, Block 60A, APN #36-00-11954-025, Lands now or formerly Liberty Property Limited Partnership, and from said point of beginning running, thence; 1. along the northeasterly legal right-of-way line of Witmer Road, North 23 degrees 42 minutes 10 seconds West, a distance of 376.11 feet to a point, thence; 2. along the dividing line between Unit 30, Block 60A, APN # 36-00-11954-016, and Unit 29, Block 60A, APN # 36-00-11954-007, Lands now or formerly Liberty Property Limited Partnership, North 44 degrees 49 minutes 22 seconds East, a distance of 428.99 feet to a railroad spike, thence; 3. along the dividing line between Unit 30, Block 60A, APN # 36-00-11954-016 and Unit 22, Block 60A, APN # 36-00-10235-052, Lands now or formerly Liberty Property Limited Partnership, South 45 degrees 10 minutes 38 seconds East, a distance of 350.00 feet to a concrete monument; 4. along the dividing line between Unit 30, Block 60A, APN #36-00-11954-016 and Unit 1, Block 60A, APN # 35-00-11954-025, South 44 degrees 49 minutes 22 seconds West, a distance of 566.68 feet to a concrete monument on the northeasterly legal right-of-way of Witmer Road and the point and place of beginning. Containing 174,242 square feet or 4.000 acres, more or less. TOGETHER WITH easements as set forth in Easement Agreement between Liberty Property Limited Partnership, a Pennsylvania limited partnership and Neose Technologies, Inc., a Delaware corporation, dated January 24, 2002 and recorded January 30, 2002 in the Office of the Recorder of Deeds in and for the County of Montgomery, Pennsylvania in Deed Book 5393 at Page 2346. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 48 102 WITMER ROAD, HORSHAM, PA EXHIBIT I BILL OF SALE AND ASSIGNMENT THIS BILL OF SALE AND ASSIGNMENT ("BILL OF SALE") is made as of September _______________, 2006, by NEOSE TECHNOLOGIES, INC., a Delaware corporation ("SELLER"), to ARE-PA REGION NO. 6, LLC, a Delaware limited liability company ("BUYER"). RECITALS A. Seller is the owner of that certain real property known as 102 Witmer Road, Horsham, Pennsylvania 19044 (the "REAL PROPERTY"). B. Buyer and Seller have entered into that certain Purchase and Sale Agreement and Joint Escrow Instructions dated as of September __, 2006 (the "PURCHASE AGREEMENT"), with respect to, among other things, the acquisition of the "PERSONAL PROPERTY" and the "INTANGIBLE PROPERTY," and certain other property. C. The Purchase Agreement requires Seller to convey all of Seller's right, title and interest in, to and under the Personal Property and the Intangible Property to Buyer. NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Seller hereby agrees as follows: 1. Unless the context otherwise requires, all capitalized terms used but not otherwise defined herein shall have the respective meanings provided therefor in the Purchase Agreement. 2. Seller does hereby unconditionally, absolutely, and irrevocably grant, bargain, sell, transfer, assign convey, set over and deliver unto Buyer all of Seller's right, title and interest in and to: A. Personal Property; and B. Intangible Property and, together with the Personal Property, the "PROPERTY." 3. Seller represents and warrants that its title to the Property is free and clear of all liens, mortgages, pledges, security interests, prior assignments, encumbrances and claims of any nature other than the Permitted Exceptions. Auxilium Pharmaceuticals, Inc., a Delaware corporation, shall be an intended third party beneficiary of the provisions of this Section 3 of this Bill of Sale and shall have the right to enforce the provisions of this Section 3 as fully as Buyer. 4. Seller hereby agrees to indemnify, protect, defend and hold Buyer harmless from and against any and all claims, losses, damages, costs and expenses (including, without limitation, reasonable attorney's fees and disbursements) incurred or suffered by Buyer in (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 49 102 WITMER ROAD, HORSHAM, PA connection with the Property and arising prior to the Closing. Buyer hereby agrees to indemnify, protect, defend and hold Seller harmless from and against any and all claims, losses, damages, costs and expenses (including, without limitation, reasonable attorney's fees and disbursements) incurred or suffered by Seller in connection with the Property and arising on or after the Closing. 5. This Bill of Sale shall be binding upon and inure to the benefit of the parties hereto and their respective successors and assigns. 6. This Bill of Sale and the legal relations of the parties hereto shall be governed by and construed and enforced in accordance with the laws of the Commonwealth of Pennsylvania, without regard to its principles of conflicts of law. [SIGNATURES ON NEXT PAGE] (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 50 102 WITMER ROAD, HORSHAM, PA IN WITNESS WHEREOF, this Bill of Sale was made and executed as of the date first above written. SELLER: NEOSE TECHNOLOGIES, INC., a Delaware corporation By: ------------------------------------ Its: ----------------------------------- (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 51 102 WITMER ROAD, HORSHAM, PA EXHIBIT J FORM OF CC&R ESTOPPEL Re: 102 Witmer Road Horsham Township, Pennsylvania DECLARATION ESTOPPEL CERTIFICATE THIS DECLARATION ESTOPPEL CERTIFICATE ("THIS CERTIFICATE") has been executed this _________ day of September, 2006, by LIBERTY PROPERTY LIMITED PARTNERSHIP, a Pennsylvania limited partnership (the "DECLARANT"), to and for the benefit of ARE-PA REGION NO. 6, LLC, a Delaware limited liability company ("ARE-PA"). ARE-PA and its successors and assigns are collectively referred to as "BENEFICIARY". RECITALS: A. Beneficiary has now or will soon hereafter acquire fee simple title to the above-referenced property situate and lying in Horsham Township, Montgomery County, Pennsylvania (the "PROPERTY"). The current owner of the Property is Neose Technologies, Inc., a Delaware corporation ("CURRENT OWNER"). B. Reference is made to (1) the Declaration of Covenants, Conditions, and Restrictions by The Prudential Insurance Company of America, as the original "Declarant" thereunder, dated February 28, 1983 and recorded among the Land Records of Montgomery County, Pennsylvania (the "LAND RECORDS") in Book 4702, Page 1770, as amended by that certain (a) First Amendment to Declaration of Covenants, Conditions and Restrictions dated February 12, 1992 and recorded among the Land Records in Deed Book 5103, Page 2212, and subsequently re-recorded in Deed Book 5109, Page 1579, (b) Second Amendment to Declaration of Covenants, Conditions and Restrictions and First Amendment to Assignment of Easement dated January 17, 1995 and recorded among the Land Records in Deed Book 5103, Page 2224, and subsequently re-recorded in Deed Book 5109, Page 1586, and (c) Third Amendment to Declaration of Covenants, Conditions and Restrictions dated February 18, 2000 and recorded among the Land Records in Deed Book 5310, Page 0904 (collectively, the "PRUDENTIAL DECLARATION"), and (2) the Declaration of Covenants and Restrictions by and between Pennsylvania Business Campus Delaware, Inc., as the original "Approving Agent" thereunder ("PBCD"), and the Current Owner, dated March 13, 1997 and recorded among the Land Records in Deed Book 5180, Page 1587 (the "PBCD DECLARATION")(the Prudential Declaration and the PBCD Declaration hereinafter sometimes collectively referred to as the "DECLARATIONS"). C. As of the date of this Certificate, Declarant is (1) the "Declarant" under the Prudential Declaration and (2) the "Approving Agent" under the PBCD Declaration. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 52 102 WITMER ROAD, HORSHAM, PA D. Beneficiary has requested and Declarant has agreed to deliver this Certificate with respect to certain matters covered under the Declarations. In consideration of the recitals set forth above, Declarant hereby represents, warrants and certifies to Beneficiary, and otherwise consents and approves, the following: 1. Declarations. (A). Prudential Declaration. (1) Declarant. As of the date hereof, Declarant is the "Declarant" under the Prudential Declaration with the rights, privileges and responsibilities granted the "Declarant" thereunder. As of the date hereof, Declarant owns more than 60% of the Property (as defined in the Prudential Declaration). (2) Full Force and Effect; No Defaults. The Prudential Declaration is currently in full force and effect and has not been further amended, supplemented or revised. Declarant hereby confirms and certifies to Beneficiary that, to the best of Declarant's actual knowledge, without independent investigation, the Property and the current Owner are not in default under the Prudential Declaration. (3) Assessments. As of the date hereof, all assessments, penalties and other payments due under the Declaration with respect to the Property, if any (including any allocable maintenance costs and expenses with respect to the "Easement Area" (as defined in Section 7 of the Prudential Declaration)) have been paid, and there are no sums due and payable with respect to the Property. With respect to the "Easement Area", the Property has previously been assessed $______________________________ monthly/quarterly/annually, and assessments from and after the date hereof are estimated to be $_____________________________ on a monthly/quarterly/annual basis. (4) Improvements. To the best of Declarant's actual knowledge, without independent investigation, all improvements located upon the Property as of the date hereof have been constructed in accordance with, and are otherwise not in violation of, the terms, conditions, provisions and requirements of the Prudential Declaration (including, but not limited to, Sections 2 and 3 thereof). (B). PBCD Declaration. (1) Declarant. As of the date hereof, Declarant is the "Approving Agent" under the PBCD Declaration with the rights, privileges and responsibilities granted the "Approving Agent" thereunder. (2) Full Force and Effect; No Defaults. The PBCD Declaration is currently in full force and effect and has not been further amended, supplemented or revised. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 53 102 WITMER ROAD, HORSHAM, PA Declarant hereby confirms and certifies to Beneficiary that, to the best of Declarant's actual knowledge, without independent investigation, the Property and the Current Owner are not in default under the PBCD Declaration. (3) Assessments. To the best of Declarant's actual knowledge, without independent investigation, as of the date hereof, all assessments, penalties and other payments due under the PBCD Declaration with respect to the Property, if any, have been paid, and there are no sums due and payable with respect to the Property. (4) Improvements. To the best of Declarant's actual knowledge, without independent investigation, all improvements located upon the Property as of the date hereof have been constructed in accordance with, and are otherwise not in violation of, the terms, conditions, provisions and requirements of the PBCD Declaration (including, but not limited to, Section 2 thereof). 2. Notice. Effective upon Beneficiary's acquisition of the Property, (a) Beneficiary will be entitled to all voting and other benefits under the Declarations with respect to the Property, if any; and (b) all notices, demands, or other written communication delivered by Declarant under the Declarations or any other instrument applicable thereto, shall be delivered to Beneficiary in the manner set forth therein, as applicable, to the following address (or such other or further addresses as Beneficiary may hereafter designate in writing): ARE-PA Region No. 6, LLC c/o Alexandria Real Estate Equities, Inc. 385 E. Colorado Blvd., Suite 299 Pasadena, California 91101 Attention: Corporate Secretary Re: 102 Witmer Road 3. Statement of Authority. The person(s) executing this Certificate on behalf of Declarant has the power and authority to execute and deliver this Certificate on behalf of Declarant. 4. Reliance. Declarant hereby acknowledges and agrees that Beneficiary has the right to rely and will rely on this Certificate, and the certifications and statements by Declarant herein, in connection with Beneficiary's acquisition of the Property. 5. Successors and Assigns. This Certificate shall be binding on Declarant and Declarant's successors and assigns, and shall inure to the benefit of Beneficiary. (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 54 102 WITMER ROAD, HORSHAM, PA IN WITNESS WHEREOF, this Certificate has been executed as of (but not necessarily on) the date and year first above written. WITNESS: DECLARANT: LIBERTY PROPERTY LIMITED PARTNERSHIP, a Pennsylvania limited partnership By: Liberty Property Trust, Its Sole General Partner By: - ------------------------------------- -------------------------------- Name: ------------------------------ Title: ----------------------------- (ALEXANDRIA(R) LOGO) Copyright (C) 2006, Alexandria Real Estate Equities, Inc. ALL RIGHTS RESERVED. Confidential and Proprietary - Do Not Copy or Distribute. Alexandria and the Alexandria Logo are registered trademarks of Alexandria Real Estate Equities, Inc. 55 102 Witmer Road 1 AGREEMENT TO PURCHASE AND SELL ........................................ 2 2 PURCHASE PRICE ........................................................ 2 2.1 Deposit ........................................................ 2 2.2 Balance ........................................................ 3 3 DUE DILIGENCE ......................................................... 3 3.1 Property Documents ............................................. 3 3.2 Investigations ................................................. 3 3.3 Tenants ........................................................ 3 3.4 CC&Rs .......................................................... 4 3.5 Property Questionnaire ......................................... 4 3.6 Termination Right .............................................. 4 3.7 Insurance ...................................................... 4 3.8 Indemnity and Repair ........................................... 5 3.9 Title .......................................................... 5 3.9.1 Deliveries by Seller .................................... 5 3.9.2 Buyer's Review of Title ................................. 5 3.9.3 Seller's Obligations Regarding Title .................... 6 3.9.4 Condition of Title at Closing ........................... 6 4 SELLER'S REPRESENTATIONS AND WARRANTIES ............................... 6 4.1 Authority ...................................................... 7 4.2 No Conflicts ................................................... 7 4.3 Preferential Rights ............................................ 7 4.4 Property Documents ............................................. 7 4.5 Tenant Leases .................................................. 7 4.6 Notices ........................................................ 7 4.7 Uncompleted Work ............................................... 8 4.8 Unpaid Commissions ............................................. 8 4.9 Material Information ........................................... 8 4.10 Special Assessments or Condemnation ............................ 8 4.11 Utilities ...................................................... 8 4.12 Service Contracts .............................................. 8 4.13 Employees ...................................................... 8 4.14 Bankruptcy ..................................................... 9 4.15 Existing Approvals ............................................. 9 4.16 Insurance ...................................................... 9 4.17 Litigation ..................................................... 9 4.18 Compliance with Laws ........................................... 9 4.19 Environmental Materials ........................................ 9 4.20 Survival ....................................................... 11 4.21 Seller's Knowledge ............................................. 11 4.22 As-Is .......................................................... 11
Page i 102 Witmer Road 5 BUYER'S REPRESENTATIONS AND WARRANTIES ................................ 11 5.1 No Conflicts ................................................... 11 5.2 Due Organization; Consents ..................................... 11 5.3 Buyer's Authority; Validity of Agreements ...................... 12 6 COVENANTS OF SELLER ................................................... 12 6.1 Title .......................................................... 12 6.2 Notice of Change in Circumstances .............................. 12 6.3 No Defaults; Maintenance of Property ........................... 12 6.4 Exclusive Negotiations ......................................... 12 6.5 Development Activities ......................................... 13 6.6 Service, Management and Employment Contracts ................... 13 6.7 Tenant Leases .................................................. 13 6.8 Insurance ...................................................... 13 6.9 Litigation ..................................................... 13 7 CONDITIONS PRECEDENT TO CLOSING ....................................... 13 7.1 Buyer's Conditions ............................................. 13 7.1.1 Title ................................................... 14 7.1.2 Seller's Due Performance ................................ 14 7.1.3 Condition of Property ................................... 14 7.1.4 Bankruptcy .............................................. 14 7.1.5 Estoppel Certificates ................................... 14 7.1.6 Property Questionnaire .................................. 14 7.1.7 No Moratoria ............................................ 15 7.2 Failure of Buyer's Conditions .................................. 15 7.2.1 Waive and Close ......................................... 15 7.2.2 Terminate ............................................... 15 7.3 Seller's Conditions ............................................ 15 7.3.1 Buyer's Due Performance ................................. 15 7.4 Failure of Seller's Conditions ................................. 15 8 CLOSING ............................................................... 15 8.1 Closing Date ................................................... 15 8.2 Closing Costs .................................................. 16 9 CLOSING DELIVERIES .................................................... 16 9.1 Deliveries by Seller to Escrow ................................. 16 9.1.1 Deed .................................................... 16 9.1.2 Non-foreign Affidavit ................................... 16 9.1.3 [California FTB Form 590-RE ............................. 16 9.1.4 Assignment of Leases .................................... 16 9.1.5 Bill of Sale and Assignment ............................. 16
Page ii 102 Witmer Road 9.1.6 Seller's Certificate .................................... 17 9.1.7 Updated Rent Roll ....................................... 17 9.1.8 Proof of Authority ...................................... 17 9.1.9 Other ................................................... 17 9.2 Deliveries by Buyer ............................................ 17 9.2.1 Balance, Prorations & Closing Costs ..................... 17 9.2.2 Assignment of Leases .................................... 17 9.2.3 Other ................................................... 17 9.3 Deliveries Outside of Escrow ..................................... 17 9.3.1 Tenant Leases ........................................... 17 9.3.2 Service Contracts ....................................... 18 9.3.3 Intangible Property ..................................... 18 9.3.4 Property Documents ...................................... 18 9.3.5 Personal Property ....................................... 18 9.3.6 Other ................................................... 18 10 PRORATIONS ............................................................ 18 10.1 Prorations ..................................................... 18 10.2 Preliminary Closing Statement .................................. 20 11 ESCROW ................................................................ 20 11.1 Opening of Escrow .............................................. 20 11.2 Escrow Instructions ............................................ 20 11.3 Actions by Escrow Agent ........................................ 21 11.3.1 Recording ............................................... 21 11.3.2 Funds ................................................... 21 11.3.3 Owner's Title Policy .................................... 21 11.3.4 Delivery of Documents ................................... 21 11.4 Conflicting Demands ............................................ 22 11.5 Real Estate Reporting Person ................................... 22 11.6 Destruction of Documents; Survival ............................. 22 12 RISK OF LOSS .......................................................... 23 12.1 Condemnation ................................................... 23 12.2 Casualty ....................................................... 23 13 DEFAULT ............................................................... 23 13.1 Default by Buyer ............................................... 23 13.2 Default by Seller .............................................. 24 14 BROKERS ............................................................... 24 15 CONFIDENTIALITY ....................................................... 25
Page iii 102 Witmer Road 15.1 Buyer .......................................................... 25 15.2 Seller ......................................................... 25 16 INDEMNIFICATION ....................................................... 25 17 MISCELLANEOUS PROVISIONS .............................................. 26 17.1 Governing Law .................................................. 26 17.2 Entire Agreement ............................................... 26 17.3 Modifications; Waiver .......................................... 26 17.4 Notices ........................................................ 26 17.5 Expenses ....................................................... 27 17.6 Assignment ..................................................... 27 17.6.1 Seller's Right to Assign ................................ 27 17.6.2 Buyer's Right to Assign ................................. 28 17.7 Severability ................................................... 28 17.8 Successors and Assigns; Third Parties .......................... 28 17.9 Counterparts ................................................... 28 17.10 Headings ....................................................... 28 17.11 Time of the Essence ............................................ 28 17.12 Further Assistance ............................................. 28 17.13 Number and Gender .............................................. 29 17.14 Construction ................................................... 29 17.15 Post-Closing Access to Records ................................. 29 17.16 Exhibits ....................................................... 29 17.17 Attorneys' Fees ................................................ 29 17.18 Business Days .................................................. 29
Page iv 102 Witmer Road LIST OF EXHIBITS EXHIBIT A Legal Description EXHIBIT B Personal Property Inventory EXHIBIT B-1 Excluded Personal Property EXHIBIT C Description of Property Documents EXHIBIT D Property Questionnaire EXHIBIT E Surveyor's Certificate EXHIBIT F Deed EXHIBIT G Seller's Certificate EXHIBIT H Non-Foreign Affidavit EXHIBIT I Bill of Sale and Assignment EXHIBIT J Form of CC&Rs Estoppel Page v
EX-10.1 3 w24742exv10w1.txt POST-CLOSING PROPERTY ACCESS AGREEMENT Exhibit 10.1 POST-CLOSING PROPERTY ACCESS AGREEMENT THIS POST-CLOSING PROPERTY ACCESS AGREEMENT, dated September 1, 2006, but intended to be effective as of (and expressly conditioned on) the Closing (as defined herein), is between Neose Technologies, Inc. ("Neose") and Auxilium Pharmaceuticals, Inc. ("Auxilium") relating to the property located at 102 Witmer Road, Horsham, Pennsylvania (the "Property"). BACKGROUND Neose is the current owner of the Property, and Auxilium desires to become the lessee of the Property upon its sale to ARE-PA Region No. 6, LLC ("Alexandria"). Simultaneously with the execution hereof, Neose and Alexandria have entered into a Purchase and Sale Agreement and Joint Escrow Instructions ("Agreement of Sale") for the sale and purchase of the Property, and Auxilium and Alexandria have entered into a Lease (the "Lease") for the lease of the Property. The parties anticipate the closing on the sale of the Property pursuant to the Agreement of Sale will occur on or about August 31, 2006 (the "Closing"). Pursuant to a Pre-Closing Property Access Agreement of even date herewith ("Pre-Closing Agreement") between Auxilium and Neose, Neose has agreed to permit Auxilium to enter the Property and to commence making certain alterations and improvements thereto prior to the date of Closing. In addition, Neose has requested and Auxilium has agreed that, following the Closing, Neose shall be permitted to remain in occupancy of certain portions of the Property and that Neose and Auxilium shall share certain facilities within the Property in accordance with the terms and conditions of this Agreement. TERMS In consideration of the mutual promises and covenants contained herein and intending to be legally bound hereby, the parties agree as follows: 1. NEOSE ACCESS. 1.1.Spaces. Upon Closing and consummation of the Lease, Auxilium hereby gives to Neose from the date of the Closing through February 28, 2007: (a) the exclusive right to use and occupy the laboratory and office areas of the Property designated as Neose Space in Schedule 1.1 ("Neose Space"), (b) the non-exclusive right in common with Auxilium to use and occupy the areas of the Property designated as Shared Space in Schedule 1.1 ("Shared Space"), (c) the non-exclusive right in common with Auxilium to use the Property's parking lot reasonably sufficient to accommodate Neose's access hereunder ("Parking Space"), (d) the non-exclusive right in common with Auxilium to use all corridors and other means of access to the Neose Space, the Shared Space and the Parking Space (together with the Neose Space, the Shared Space and the Parking Space, the "Spaces") and (e) the non-exclusive right in common with Auxilium to use the fax machines and copiers conveyed to Alexandria pursuant to the Agreement of Sale, and which are being leased by Alexandria to Auxilium pursuant to the Lease. The foregoing rights to use and occupy the Spaces shall be free of any and all charges. Each party agrees that access to the Shared Space by both parties may require schedules to be coordinated and/or changed from time to time to enable each party to carry out its regular business objective. Neose and Auxilium shall endeavor to have a working schedule in place by the Closing. Each party agrees that it shall provide notice to the other as soon as it is determined that a reasonable change to an agreed schedule is required. All schedules and reasonable changes to existing schedules shall be coordinated through the Representatives described below. The Spaces will be made available to Neose on an "As-Is, Where-Is" basis, without representation or warranty of any kind and Neose expressly accepts the Spaces on such basis. 1.2.Compliance. Neose will use reasonable commercial efforts to ensure that neither Neose's access to the Property, the occupancy of the Spaces, nor the conduct of its operations will interfere with Auxilium's operations at the Property or cause any harm or destruction to or contamination of the Property. Auxilium will use reasonable commercial efforts to ensure that Neose will have the right of quiet enjoyment of the Spaces and will be able to conduct its operations. Neose's use and occupancy of the Property shall at all times comply with all applicable laws, regulations, ordinances, safety requirements and SOPs of Auxilium ("Laws and Requirements"). Auxilium and Neose will comply with all procedures agreed upon by the parties. 1.3.Alterations. Neose shall not make any installations, improvements, additions, alterations, or attachments to the Spaces without the prior consent of Auxilium, such consent not to be unreasonably withheld or delayed. Neose, at its sole cost and expense, shall immediately repair any damage caused to the Spaces by Neose, its employees, invitees or contractors following the Closing. 1.4.Calibrations. Between the Closing and September 15, 2006, Neose and its calibration vendor, Integrated Service Solutions, shall have the right of access to the pilot plant, upon reasonable notice and during normal business hours, for the purpose of executing terminal calibrations and other calibrations due on Conveyed Equipment. 2. COOPERATION. 2.1.Cooperation. Neose and Auxilium shall cooperate with each other in order to agree upon and implement such reasonable procedures and reasonable protocol as are reasonably necessary to ensure the safety of each other's personnel and to ensure noninterference with each party's business operations. It is understood that, during the period of this Agreement, certain equipment designated as Shared Equipment in Schedule 2.1 will be shared by the parties. The parties agree to cooperate with each other with respect to the use of the Shared Equipment and any issues with respect to the use of the Shared Equipment shall be referred to the Working Committee (as defined below). It is also understood that, until Neose vacates the Property, Auxilium shall have the right to use up to fifty (50) lines of the existing telephone system serving the Property. 2.2.Facility Employees. Neose and Auxilium agree that the facility employees listed in Schedule 2.2 (each a "Facility Employee") shall, regardless of which party employs them, -2- continue to work together in an integrated manner to perform their current job duties of maintaining the Property for the benefit of both Neose and Auxilium and the Property, 201 Witmer Road, and 102 Rock Road, Horsham, PA. During the thirty-day period commencing on the date of Closing, to the extent he remains an employee of Neose, Neose will, upon reasonable notice and subject to his availability, make Chris Garges available to Auxilium to answer questions and otherwise provide information about the use of the Property, up to an aggregate maximum of 20 hours. 2.3.Working Committee. Neose and Auxilium hereby establish a working committee ("Working Committee"), which shall be responsible for the cooperation necessary to allow Auxilium and Neose to protect their employees and conduct their operations to manage the Facility Employees, and for communication and resolution of issues between the parties. The Working Committee shall consist of two representatives who will be authorized to act for the parties hereunder (respectively, "Neose's Representatives" and "Auxilium's Representatives", and together, the "Representatives"). The Representatives shall be available to attend regularly scheduled and special meetings with each other in person or by conference call. It is expected that regular meetings will be held weekly and may also be attended by employees or representatives of either party other than the Representatives. 2.4.Appointment of Representatives. Auxilium's Representatives will be Ben Del Tito and Michael Cowan, and Neose's Representatives will be James White and Hoyt Emmons. Each Party may remove and replace its Representatives on the Working Committee at any time, without cause, upon written notice to the other Party. Each party's Representatives shall have the authority to act on such party's behalf at all times and with respect to issues relating to this Agreement. 2.5.Dispute. In the event the Working Committee shall fail to mutually resolve any matter it is responsible for hereunder, Neose and Auxilium agree to submit such matter to the senior management of each party for mutual resolution. In the event the senior management shall fail to mutually resolve such matter, Neose and Auxilium agree to submit such matter pursuant to the Expedited Procedures provisions of the Arbitration Rules for the Real Estate Industry of the AAA (presently Rules 56 through 60); provided, however, that with respect to any such arbitration, (i) the list of arbitrators referred to in Rule 57 shall be returned within five (5) business days from the date of mailing, (ii) the parties shall notify the AAA, by telephone of any objections to the arbitrator appointed, within four (4) days after such appointment, and will have no right to object if the arbitrator so appointed was on the list submitted by the AAA and was not objected to in accordance with Rule 57, (iii) the notice of hearing referred to in Rule 58 shall be four (4) days in advance of the hearing, (iv) the hearing shall be held within seven (7) days after the appointment of the arbitrator, and (v) the arbitrator shall have no right to award damages. 3. INSURANCE. 3.1. Neose shall, at its expense, maintain or cause its contractors to maintain during the period of access hereunder commercial general liability insurance, including contractual liability insurance and property damage insurance under policies issued by insurers licensed to conduct business in the state wherein the Property is located, with per -3- occurrence limits of not less than $5 Million for bodily injury, or death and damage to or destruction of property (including the loss of use thereof), $5 Million combined aggregate, and workers' compensation at statutory limits. Such policies shall name Auxilium, Alexandria, Alexandria Real Estate Equities, Inc., and its and their respective officers, directors, members, and employees as additional insureds. Neose shall deliver to Auxilium and Alexandria certificates of insurance evidencing such coverage prior to entering upon the Property. Such certificates shall contain a provision that same shall not be cancelled or the coverage materially altered without first giving at least thirty days' prior written notice to Auxilium and Alexandria. 3.2. Any policy or policies of fire, extended coverage or similar property insurance, which either party obtains in connection with the Property, shall include a clause or endorsement denying the insurer any rights of subrogation against the other party for all perils covered by such policy. Any provision of this Agreement to the contrary notwithstanding, Neose and Auxilium hereby release the other from any and all liability or responsibility to the other or anyone claiming through or under them by way of subrogation or otherwise (a) from any and all liability for any loss or damage to the property of the releasing party, (b) for any loss or damage that may result, directly or indirectly, from the loss or damage to such property (including rental value and business interruption), and (c) from legal liability for any loss or damage to property (no matter who the owner of the property may be), all to the extent that the releasing party's loss or damage is insured or, if not insured, was insurable under commercially available "special form" property insurance policies, including additional coverages typically obtained by owners and users of comparable facilities, even if such loss or damage or legal liability shall be caused by or result from the fault or negligence of the other party or anyone for whom such party may be responsible and even if the releasing party is self-insured in whole or in part or the amount of the releasing party's insurance is inadequate to cover the loss or damage or legal liability. It is the intention of the parties that Neose and Auxilium shall look solely to their respective insurance carriers for recovery against any such property loss or damage or legal liability, without such insurance carriers having any rights of subrogation against the other party. 4. INDEPENDENT CONTRACTORS. Neose and Auxilium are independent contractors hereunder and, except as otherwise provided herein, shall conduct their respective businesses as they may determine, and neither party, nor any officer, employee or agent of either party, shall have the authority to bind the other party in any way whatsoever, or to accept service of legal process for and on behalf of the other party pursuant to this Agreement. Neither Neose nor Auxilium shall be deemed in any way or for any purpose, to have become, by the execution of this Agreement or any action taken hereunder, a partner of the other party in its business or a joint venturer or a member of a joint enterprise with the other party. 5. TECHNICAL INFORMATION. Pursuant to the Agreement of Sale, Neose is conveying to Alexandria, to the extent available and in its possession, Neose's non-proprietary standard operating procedures specifically relating to the Property and the maintenance of the personal property being conveyed by Neose to Alexandria at Closing pursuant to the Agreement of Sale ("Conveyed Equipment"), validation protocols for all Conveyed Equipment and facility systems, and equipment turnover packages and equipment history files relating to the Conveyed Equipment and facility systems ("Technical Information"). Neose agrees that Alexandria may -4- share the Technical Information with Auxilium. Auxilium agrees that, during the term of this Agreement, the Technical Information will be retained at the Property and that Neose may make copies of any or all of the Technical Information. Neose agrees that it shall not remove any of the Conveyed Equipment or Technical Information (except as necessary to make copies). Neose further agrees that, upon expiration or earlier termination of this Agreement, Neose shall leave all the Conveyed Equipment and Technical Information (other than copies made by Neose) at the Property. Neose acknowledges that, to the extent Auxilium supplements or modifies the Technical Information after the Closing, Neose will have no rights with respect to such supplemental or modified Technical Information. 6. WAREHOUSE FACILITY. Subject to Neose's landlord's consent, and a separate agreement among such landlord, Auxilium and Neose, Neose will assign or sublet the warehouse space at 201 Witmer Road, Horsham, PA to Auxilium effective as of the Closing for the remainder of the current lease term, at the same current lease rates and charges, and Auxilium will allow Neose to occupy a portion of the warehouse space as designated in Schedule 6, free of charge, for the remainder of the current lease term. Within two (2) days from the date hereof, Neose shall request the landlord of 201 Witmer Road to consent to the foregoing described lease assignment or sublease. 7. SURRENDER. As of February 28, 2007, Neose shall (i) vacate and surrender the Spaces to Auxilium in broom clean condition, (ii) remove all of Neose's property, fixtures and equipment (including the components of the existing telephone system not included as part of the Conveyed Equipment other than cabling, wires and connections within walls, above ceilings or beneath floors) from the Spaces, (iii) restore any damage caused by the removal of any property, fixtures and equipment of Neose, (iv) decontaminate, repair, or clean-up the Spaces to remove any contamination from the Spaces resulting from Neose's operations following Closing to standards reasonably acceptable to Auxilium and (v) remove the exterior hazardous materials shed from the Property and any contamination resulting from the shed following Closing to standards reasonably acceptable to Auxilium. 8. ASSIGNMENT. Auxilium and Neose shall not be permitted to assign their rights or obligations hereunder. 9. TERM. This Agreement shall expire and terminate effective as of February 28, 2007, except with respect to the obligations of the parties set forth in paragraphs 4, 6, 8, 9, and 11 which shall survive termination. If Neose fails to vacate the Property by 12:00 a.m. on March 1, 2007 for any reason, then for each and every day that Neose fails to so vacate, it shall pay to Auxilium the sum of $1,000 per day. This charge shall not limit Auxilium's right to seek such other remedies as may be available to Auxilium either at law or in equity. 10. MECHANIC'S LIENS. Neose shall not cause or permit the attachment of any mechanic's lien, materialman's lien, or any other lien, claim or encumbrance ("Encumbrance") against the Property. In the event of such Encumbrance, Neose shall bear all cost and expense related to the defense or removal of same and indemnify and hold Auxilium harmless from any actual and documented cost or expense (including reasonable attorneys' fees) which Auxilium may incur in connection therewith. -5- 11. INDEMNITY. 11.1. Neose shall indemnify, defend and hold Auxilium free and harmless from and against any and all claims, liabilities, damages, losses, actual and documented costs or expenses (including reasonable attorneys' fees) to the extent arising from Neose's activities on the Property; any act or omission of Neose or anyone acting by or on behalf of Neose at or about the Property in connection with this Agreement or otherwise; and any failure of Auxilium to comply with the terms of this Agreement. 11.2. Auxilium shall indemnify, defend and hold Neose free and harmless from and against any and all claims, liabilities, damages, losses, actual and documented costs or expenses (including reasonable attorneys' fees) to the extent arising from (i) any claim by a third party alleging injury due to the negligence, gross negligence or willful misconduct of Auxilium, and (ii) any grossly negligent act or willful misconduct of Auxilium or anyone acting by or on behalf of Auxilium at or about the Property. 12. RELEASE. In order to induce Auxilium to permit Neose to access the Property, Neose, on behalf of itself, its officers, employees, representatives, agents and contractors (collectively, "Neose Releasors") hereby expressly RELEASE AND FOREVER DISCHARGE Auxilium, its employees, agents, contractors and representatives (collectively, "Auxilium Releasees") from any and all expenses, losses, costs, liabilities, claims, causes of action, demands and damages for loss, damage, injury or death to the Auxilium Releasees, or any of them (except to the extent resulting from the gross negligence or willful misconduct of the Auxilium Releasees), or damage to the property of Neose Releasors, or any of them, arising out of or in connection with the Neose's use and occupancy of the Property. 13. SERVICE CONTRACTS. 13.1. As of Closing, Neose (i) hereby assigns, transfers and sets over unto Auxilium, and as of Closing Auxilium hereby accepts, all Neose's rights, title and interest in and to those certain contracts listed in Part A of Schedule 13.1, which Contracts pertain solely to the Property or Conveyed Equipment and are immediately assignable ("Assignable Contracts"), and (ii) will cooperate with Auxilium to obtain the consent of the other party to, and assign, transfer, and set over to Auxilium the contracts listed in Part B of Schedule 13.1, which contracts pertain solely to the Property or Conveyed Equipment and require consent for assignment ("Consent Contracts" and together with the Assignable Contracts, the "Contracts"). From and after the Closing, Neose and Auxilium will use commercially reasonable efforts to arrange for the transfer to Auxilium the rights and obligations under the contracts listed in Part C of Schedule 13.1, which rights and obligations relate solely to the Property or Conveyed Equipment ("Combined Contracts"). 13.2. Neose represents and warrants to Auxilium that: (a) the Contracts have not been assigned previously and are not subject to any lien or encumbrance, (b) all sums required to be paid as of the date hereof under the Contracts have been paid, and (c) the copies of the Contracts previously provided to Auxilium are true correct and complete and constitute the entire agreement between Neose and the respective contractors under the Contracts. -6- 13.3. Neose shall be responsible for the observance and performance of all its agreements and obligations under the Contracts arising prior to Closing. 13.4. Auxilium hereby assumes and agrees to perform all of the covenants, agreements and obligations of Neose arising out of or relating to the Contracts which first arise and relate to the period from and after the Closing. 13.5. Neose shall to the extent permitted by law, defend, protect, indemnify and save harmless Auxilium from and against any and all liabilities, suits, actions, losses, damages, costs and expenses, including without limitation counsel fees, suffered or incurred by Auxilium resulting from or relating to any failure by Neose to observe or perform any of its agreements or obligations under the Contracts prior to Closing. 13.6. Auxilium shall defend, protect, indemnify and save harmless Neose from and against any and all liabilities, suits, actions, losses, damages, costs and expenses, including without limitation counsel fees, suffered or incurred by Neose resulting from or relating to any failure by Auxilium to observe or perform any of its agreements or obligations under the Contracts on or after the Closing. 13.7. At Closing, the expenses relating to the Contracts shall be prorated between Auxilium and Neose and Auxilium shall pay to Neose the amount that Neose has paid prior to Closing for post-Closing time periods. 14. MISCELLANEOUS. 14.1. This Agreement may be executed in several counterparts, all of which constitute one and the same instrument. 14.2. This Agreement shall be governed by and construed in accordance with the laws of the Commonwealth of Pennsylvania. 14.3. The language of this Agreement shall be construed according to its normal and usual meaning and not strictly for or against either Neose or Auxilium. The rule of construction which allows a court to construe a document more strictly against its author shall not govern the interpretation of this Agreement. 14.4. If any provision of this Agreement, or its application to any situation, shall be invalid or unenforceable to any extent, the remainder of this Agreement, or the application thereof to situations other than as to which it is invalid or unenforceable, shall not be affected thereby, and every provision of this Agreement shall be valid and enforceable to the fullest extent permitted by law. 14.5. This Agreement, together with the Pre-Closing Agreement and the Confidentiality and Nondisclosure Agreement dated March 1, 2006, as amended by the Pre- Closing Agreement, constitutes the entire agreement, and supersedes the letter agreement dated July 26, 2006, between the parties relating to the subject matter hereof, and may be amended only by written agreement of the parties. No representations, inducements, promises or agreements, oral or otherwise, between Neose or Auxilium or any of their -7- respective brokers, employees or agents, not embodied herein, shall be of any force or effect. This Agreement is subject and subordinate in all respects to the Consent to Property Access Agreements of even date herewith among Alexandria, Neose, and Auxilium. 14.6. This Agreement shall be binding upon and shall inure to the benefit of the parties hereto, their heirs, executors, administrators, successors and permitted assigns. 14.7. Notices. All notices provided for or permitted under this Agreement shall be in writing and shall be: (i) delivered personally; (ii) sent by facsimile with return facsimile confirmation; (iii) sent by commercial overnight courier with written verification of receipt; or (iv) sent by certified or registered U.S. mail, postage prepaid and return receipt requested, to the party to be notified, at the address for such party set forth below, or at such other address of which such party has provided notice in accordance with the provisions of this paragraph: To Auxilium: To Auxilium: Auxilium Pharmaceuticals, Inc. Attn: General Counsel 40 Valley Stream Parkway Malvern, PA 19355 Fax: (484) 321-2208 To Neose: Neose Technologies, Inc. Attn: General Counsel 102 Witmer Road Horsham, PA 19044 Notices shall be deemed effective (i) if delivered in person, when delivered; (ii) if delivered by facsimile, on the date of receipt of facsimile confirmation; (iii) if delivered by commercial overnight courier, on the date of written verification of receipt; or (iv) if delivered by certified or registered U.S. mail, five business days after deposit in the mail. 14.8. Neose and Auxilium agree that time is of the essence of this Agreement. -8- IN WITNESS WHEREOF, Neose and Auxilium, intending to be legally bound hereby, have signed this Agreement as of the day and year first above written. Neose Technologies, Inc. Auxilium Pharmaceuticals, Inc. By: /s/ A. Brian Davis By: /s/ James E. Fickenshear --------------------------------- ------------------------------------ Name: A. Brian Davis Name: James E. Fickenshear ------------------------------- ---------------------------------- Title: SVP and CFO Title: Chief Financial Officer ------------------------------ --------------------------------- Schedule 1.1 Neose Space SCHEDULE 1.1 (FLOOR PLAN) 102 Witmer - Post-Close Agreement -10- Schedule 2.1 Shared Equipment SCHEDULE 2.1 CONFIDENTIAL WITMER ROAD PROPERTY - SHARED ASSETS
FAS EQUIPMENT FAS SYSTEM # TAG # TAG # ACQ DATE VENDOR DESCRIPTION LOCATION SERIAL NUMBER - -------- --------- ----- ---------- ----------------- --------------------------------------- -------- -------------- 729 M-01 00107 4/24/2000 Fisher Scientific Microscope-Zeiss-Axiostar Lab 1 33485 N/A VT-116 Mini Vortexer Lab 1 2-375976 1,576 KF-02 01078 10/23/2003 Fisher Scientific KFD Titrino 758/B-20 WR LAB 9 10576598 527 ST01 00958 Lunaire Environmental-(4) stability chambers WR LAB 9 Neose # ST 01 537 ST02 00957 Lunaire Environmental- see # 527 notes WR LAB 9 Neose # ST 02 536 ST03 00956 Lunaire Environmental- see # 527 notes WR LAB 9 Neose # ST 03 528 ST04 00955 Lunaire Environmental- see # 527 notes WR LAB 9 Neose # ST 04 1,695 ST05 01164 4/30/2004 Fisher -20 degree C, 208V general purpose free WR Lab 9 P250-104110-RO 1,699 ST06 01163 4/30/2004 Fisher Scientific Ultima II SI Series ultralow-temp freez WR Lab 9 R220-208039-RO 2,191 ST07 01432 4/30/2005 Fisher Scientific 32 cu ft Revco Environmental Chamber QC lab 31958
Page 1 of 1 Schedule 2.2 "Facility Employee" Walter Waldspurger Terry White Robert Livezey Steven Pinkney Richard Faust Joseph Engart Harry Santoo Aurelia Colding -12- Schedule 6 Warehouse Facility (FLOOR PLAN) 201 Witmer - Post-Close Agreement -13- SCHEDULE 13.1 SERVICE CONTRACTS A. Assignable Contracts are held with the following vendors: - AT Chadwick Service Company+ - Brickman Group - Critical Cleaning, Inc. - Electronic Security Corp. - Lancer USA+ - Neu-Ion - Stericycle - Steris B. Consent Contracts are held with the following vendors: - Allied Waste/BFI - Johnson Controls+ C. Combined Contracts are held with the following vendors: - Agilent+* - Alfa Laval - Beckman Coulter+* - GE Analytical Instruments, Inc.+ - Integrated Service Solutions - JC Ehrlich Co., Inc. - Klenzoid Water Treatment+ - Ransome - Thermo Electron Corporation+ * Consent required for assignment. + The agreements with these vendors have been prepaid in full or in part and a pro-ration must be made upon the transfer of assets pursuant to the Agreement.
EX-10.2 4 w24742exv10w2.txt CONSENT TO PROPERTY ACCESS AGREEMENT Exhibit 10.2 CONSENT TO PROPERTY ACCESS AGREEMENT THIS CONSENT TO PROPERTY ACCESS AGREEMENTS (this "CONSENT") is made as of September 1, 2006, by ARE-PA REGION NO. 6, LLC, a Delaware limited liability company, having an address of 385 E. Colorado Blvd., Suite 299, Pasadena, California 91101 ("ARE"), AUXILIUM PHARMACEUTICALS, INC., a Delaware corporation, having an address of 40 Valley Stream Parkway, Malvern, Pennsylvania 19355 ("AUXILIUM"), and NEOSE TECHNOLOGIES, INC., a Delaware corporation, having an address of 102 Witmer Road, Horsham, Pennsylvania 19044 ("NEOSE") with reference to the following Recitals. RECITALS A. ARE, as buyer, and Neose, as seller, have entered into a Purchase and Sale Agreement and Joint Escrow Instructions dated as of September __, 2006 ("AGREEMENT OF SALE") for the purchase and sale of the property known as 102 Witmer Road, Horsham, Pennsylvania 19044 ("PREMISES"). B. ARE, as landlord, and Auxilium, as tenant, have entered into that certain Lease Agreement of even date herewith ("LEASE"), wherein ARE has leased the Premises to Auxilium. C. Pursuant to the terms and conditions of a certain Pre-Closing Property Access Agreement ("PRE-CLOSING AGREEMENT") between Neose and Auxilium, Neose has agreed to permit Auxilium to enter the Premises and to commence making certain alterations and improvements thereto before the date on which the Premises are conveyed to ARE pursuant to the Agreement of Sale ("CLOSING"). D. Pursuant to the terms and conditions of a certain Post-Closing Property Access Agreement ("POST-CLOSING AGREEMENT") between Neose and Auxilium, Auxilium has agreed to permit Neose to remain in occupancy of certain portions of the Premises and to share certain facilities within the Premises for a defined period of time after the Closing. The Pre-Closing Agreement and the Post-Closing Agreement are hereinafter collectively referred to as the "PROPERTY ACCESS AGREEMENTS." E. Auxilium and Neose desire to obtain ARE's consent to the Property Access Agreements. NOW, THEREFORE, in consideration of the foregoing and the agreements contained herein, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, ARE hereby consents to (a) Auxilium's entry onto the Premises and the making of certain alternations and improvements by Auxilium before the Closing, and (b) Neose's use and occupancy of certain portions of the Premises between the Closing and February 28, 2007, such consent being subject to and upon the following terms and conditions to which Auxilium and Neose hereby agree: 1. All initially capitalized terms not otherwise defined in this Consent shall have the meanings set forth in the Lease unless the context clearly indicates otherwise. 2. This Consent shall not be effective and the Property Access Agreements shall not be valid unless and until ARE shall have received: (a) fully executed counterparts of the Property Access Agreements, and (b) a fully executed counterpart of this Consent. Auxilium and Neose each represent and warrant to ARE that true, correct, and complete copies of the Property Access Agreements are attached hereto as EXHIBIT A. 3. ARE's consent to Auxilium Improvements and Approved Materials shall be as follows: a. Prior to the construction or installation of any alterations, addition or improvements to the Premises by Auxilium before the Closing (collectively, "AUXILIUM IMPROVEMENTS"), ARE shall have received and approved, pursuant to the terms and conditions set forth in the Lease, any drawings for the proposed Auxilium Improvements. The Auxilium Improvements shall be installed, maintained, repaired, replaced, and removed in accordance with the terms and conditions of the Lease; and b. Prior to Auxilium introducing any Approved Materials (as defined in the Pre- Closing Agreement) into the Premises before the Closing, ARE shall have received and approved a reasonably detailed itemization of the Approved Materials, and all documents relating to Auxilium's proposed use of the Premises. 4. ARE neither approves nor disapproves the terms, conditions, and agreements contained in the Property Access Agreements, all of which shall be subordinate and at all times subject to: (a) all of the covenants, agreements, terms, provisions, and conditions contained in the Lease, (b) superior ground leases, Mortgages, or any other hypothecation or security now existing or hereafter placed upon all or any part of the Premises and to any advances secured thereby and to all renewals, modifications, consolidations, replacements, and extensions thereof, and (c) all matters of record affecting the Premises and all Legal Requirements now or hereafter affecting the Premises. 5. Nothing contained herein or in the Property Access Agreements shall be construed to modify, waive, impair, or affect any of the terms, covenants, or conditions contained in the Lease, or to waive any breach thereof, or any rights or remedies of ARE under the Lease against any person, firm, association, corporation, or entity liable for the performance thereof, or to enlarge or increase ARE's obligations or liabilities under the Lease, and all terms, covenants, and conditions of the Lease are hereby declared by each of ARE and Auxilium to be in full force and effect. Auxilium shall remain liable and responsible for the due keeping, performance, and observance of all the terms, covenants, and conditions set forth in the Lease on the part of Auxilium to be kept, performed, and observed and for the payment of the Base Rent, Additional Rent, and all other sums now and hereafter becoming payable thereunder for all of the Premises. 6. Notwithstanding anything in the Property Access Agreements to the contrary: a. From and after the Closing and through the expiration of the Post-Closing Agreement on February 28, 2007 or, if earlier, the date Neose vacates the Premises, Neose does hereby expressly assume and agree to be bound by and to perform and comply with, for the benefit of ARE, each and every obligation of Auxilium under the Lease, except as specifically set forth otherwise below, to the extent applicable to the use and occupancy (and not related to the payment of rent or additional rent) of those portions of the Premises used and occupied by Neose or shared by Neose and Auxilium, but in no event shall Neose be liable for 2 the acts or omissions of Auxilium under the Lease (except to the extent due to the acts or omissions of Neose and its agents, contractors, and employees). ARE and Neose each hereby release the other, and waive their respective rights of recovery against the other for direct or consequential loss or damage arising out of or incident to the perils covered by property insurance carried by such party to the extent of such insurance and waive any right of subrogation which that otherwise exist in or accrue to any person on account thereof. b. Auxilium and Neose agree to each of the terms and conditions of this Consent, and upon any conflict between the terms of the Property Access Agreements and this Consent, the terms of this Consent shall control. In case of a conflict between the terms of this Consent and the Lease, the terms of the Lease shall control. c. The Property Access Agreements shall be deemed and agreed to be use and occupancy agreements only and not a sublease or an assignment and there shall be no further use and occupancy agreements, subletting, or assignment of all or any portion of the Premises except in accordance with the terms and conditions of the Lease. d. If ARE terminates the Lease as a result of an uncured default by Auxilium thereunder or the Lease terminates for any other reason (except a termination by reason of casualty or condemnation), the Post-Closing Agreement shall automatically terminate concurrently therewith and the Lease shall become a direct lease between ARE and Neose with respect to the Spaces as defined in Section 1.1 of the Post Closing Agreement; provided, however, that such direct lease shall be amended to reflect the following: (i) an expiration date of February 28, 2007 or, if earlier, the date Neose vacates the Premises with no renewal or extension option in favor of Neose; (ii) Neose will not be obligated to pay Rent (pursuant to Sections 3, 4, 5, 9, 17 or otherwise of the Lease) on account of Base Rent, Additional Rent, Operating Expenses or otherwise, for the period between the date of the termination of the Lease and February 28, 2007, except as provided in clauses (iii), (v), and (vii) below; (iii) Neose shall be obligated to pay as Additional Rent the per diem sum of $60 per rentable square foot (on an annualized basis) pursuant to Section 8 of the Lease arising from Neose's holdover of the Premises beyond February 28, 2007; such per diem amount shall be based on the rentable square footage of the Neose Space and Shared Space (as defined in the Post-Closing Agreement) as reasonably determined by Landlord; (iv) Neose shall not be obligated to deposit any security deposit or other collateral with Landlord pursuant to Section 6 of the Lease; (v) Neose shall only be obligated for its prorata share ("NEOSE'S PRORATA SHARE") of the cost of utilities serving the Spaces (as defined in the Post-Closing Agreement) where Neose's Prorata Share shall be equal to the ratio that the 3 Neose Space and the Shared Space used and occupied by Neose bears to the entire Premises; (vi) Except to the extent Neose deems necessary for the continued use and occupancy of the Spaces by it and subject to the provisions of this Consent, that Neose shall have no obligation to perform the obligations set forth in Sections 11(b) (except that Neose shall maintain, at its sole cost and expense, the generator described in Section 11(b) (the "GENERATOR") so as to keep the Generator in operational condition and repair and otherwise comply with applicable Legal Requirements governing the use and operation of the Generator), 12, 13, 14, or Exhibit C to the Lease. (vii) Neose shall (A) have no right to make any Alterations to the Premises except in compliance with the provisions of the Lease, (B) have no right to use all or any part of the TI Allowance under the Work Letter contained in Exhibit C to the Lease; (C) not take any action to adversely affect the validated state of the cGMP Systems and Building Infrastructure; (D) pay as Additional Rent Neose's Prorata Share of the costs incurred by ARE to maintain and repair the Premises; and (E) have no obligation to pay the cost of any capital repairs or improvements made by Landlord to the Premises after the Closing (it being understood and agreed that Landlord shall have no obligation whatsoever to make any such capital improvements); (viii) Neose shall have no obligation pursuant to Sections 28 or 30 of the Lease; provided, however, that Neose shall be obligated to surrender the Spaces in the manner required by the Post-Closing Agreement and as may be required by Environmental Requirements (as defined in Section 30 of the Lease) and in the state of repair and condition in which the Spaces were delivered to Neose on the date of Closing (ordinary wear and tear excepted); (ix) Neose shall not be required to maintain property insurance with respect to the Spaces other than as Neose may elect with respect to its personal property; (x) Neose shall not be in default of its obligation under the Lease (to the extent Neose has obligations under the Lease) if it vacates the Premises prior to February 28, 2007; and (xi) ARE shall have no obligation under the Lease or otherwise to restore all or any part of the Premises based on casualty or condemnation. ARE shall not (A) be liable for any prior act or omission of Auxilium under the Lease before the termination of the Lease or for any other defaults of Auxilium under the Property Access Agreements, (B) be subject to any defenses or offsets previously accrued that Neose may have against Auxilium for any period before the termination of the Lease, or (C) be bound by any changes or modifications made to the Property Access Agreements without the prior written consent of ARE as set forth in this Consent. e. Neose hereby agrees to indemnify, defend, and hold ARE free and harmless from and against any and all claims, liabilities, damages, losses, actual and documented costs or expenses (including reasonable attorneys' fees) to the 4 extent arising from, or relating to, the use and occupancy of the Premises by Neose after the Closing and any act or omission of Neose or anyone acting by or on behalf of Neose at or about the Premises in connection with, or arising out of, the Property Access Agreements or otherwise. In no event shall Neose be liable for any act or omission of Auxilium under the Lease (except to the extent due to the acts or omissions of Neose and its agents, contractors, and employees) nor shall Neose be obligated to indemnify ARE for (i) any Claims arising out of any act or omission of Auxilium pursuant to Section 7 of the Lease (except to the extent due to the acts or omissions of Neose and its agents, contractors, and employees); (ii) any expenses incurred by ARE pursuant to Section 12 of the Lease; (iii) any Claims for which ARE may be entitled to indemnification pursuant to Section 16 of the Lease except to the extent due to the acts or omissions of Neose and its agents, contractors, and employees occurring after Closing; or (iv) any Environmental Claims except to the extent due to the acts or omissions of Neose and its agents, contractors, and employees occurring after Closing. f. Auxilium hereby agrees to indemnify, defend, and hold ARE free and harmless from and against any and all claims, liabilities, damages, losses, actual and documented costs or expenses (including reasonable attorneys' fees) to the extent arising from, or relating to the entry onto the Premises by Auxilium before the Closing, and any act or omission of Auxilium or anyone acting by or on behalf of Auxilium at or about the Premises in connection with, or arising out of, the Property Access Agreements or otherwise. g. To induce ARE to permit Neose and Auxilium to use and occupy the Premises as set forth in the Property Access Agreements, Neose and Auxilium, on behalf of itself and themselves, and its and their respective officers, employees, representatives, agents and contractors (collectively, "RELEASORS"), hereby expressly RELEASE AND FOREVER DISCHARGE ARE, its members, partners, employees, agents, contractors, and representatives (collectively, "RELEASEES") from any and all expenses, losses, costs, liabilities, claims, causes of action, demands and damages for loss, damage, injury, or death to the Releasees, or any of them, or damage to the property of Releasors, or any of them, in connection with, or arising out of, the Property Access Agreements or otherwise. 7. Any act or omission of Neose or anyone claiming under or through Neose that violates any of the provisions of the Lease shall be deemed a violation of the Lease by Auxilium. 8. Upon an uncured default by Auxilium under the Lease, ARE may proceed directly against Auxilium or anyone else liable, other than Neose (unless Auxilium's default is due to Neose's default under this Consent), under the Lease or the Property Access Agreements without first exhausting ARE's remedies against any other person or entity liable thereon to ARE. If ARE gives Neose notice that Auxilium is in default under the Lease, Neose shall thereafter make directly to ARE any payments otherwise due Auxilium under the Property Access Agreements, which payments will be received by ARE without any liability to ARE except to credit such payments against amounts due under the Lease. The mention in this Consent of any particular remedy shall not preclude ARE from any other remedy in law or in equity. 9. Neose shall pay any broker commissions or fees that may be payable as a result of the Property Access Agreements and Neose hereby indemnifies and agrees to hold ARE 5 harmless from and against any loss or liability arising therefrom or from any other commissions or fees payable in connection with the Property Access Agreements that result from the actions of Neose. Auxilium hereby indemnifies and agrees to hold ARE harmless from and against any loss or liability arising from any commissions or fees payable in connection with the Property Access Agreements that result from the actions of Auxilium. 10. Auxilium and Neose agree that the Property Access Agreements will not be modified or amended in any way without the prior written consent of ARE, which consent shall not be unreasonably withheld. It shall be reasonable for ARE to withhold its consent if, among other reasons, (a) Neose or Auxilium proposes to extend the term of the Post-Closing Agreement, or (b) such modification or amendment would (i) adversely affect ARE or its ownership or operation of the Premises, (ii) change the permitted use of the Premises, or (iii) affect ARE's status as a real estate investment trust. Any modification or amendment of the Property Access Agreements without ARE's prior written consent shall be void and of no force or effect. 11. This Consent may not be changed orally, but only by an agreement in writing signed by ARE and the party against whom enforcement of any change is sought. 12. This Consent may be executed in any number of counterparts, each of which shall be deemed an original, but all of which when taken together shall constitute but one and the same instrument. 13. This Consent and the legal relations between the parties hereto shall be governed by and construed and enforced in accordance with the internal laws of the Commonwealth of Pennsylvania, without regard to its principles of conflicts of law. [SIGNATURES ON NEXT PAGE] 6 IN WITNESS WHEREOF, ARE, Auxilium, and Neose have caused their duly authorized representatives to execute this Consent as of the date first above written. AUXILIUM PHARMACEUTICALS, INC., a Delaware corporation, By: /s/ James E. Fickenshear --------------------------------- Its: Chief Financial Officer -------------------------------- NEOSE TECHNOLOGIES, INC., a Delaware corporation, By: /s/ George J. Vergis, Ph.D. --------------------------------- Its: President and CEO -------------------------------- ARE-PA REGION NO. 6, LLC, a Delaware limited liability company By: ALEXANDRIA REAL ESTATE EQUITIES, L.P., a Delaware limited partnership, managing member By: ARE-QRS CORP., a Maryland corporation, general partner By: /s/ Jennifer J. Pappas ------------------------------------ Vice President and Assistant Secretary a -------------------------------------- 7 EXHIBIT A COPY OF PROPERTY ACCESS AGREEMENTS PRE-CLOSING PROPERTY ACCESS AGREEMENT THIS IS A PRE-CLOSING PROPERTY ACCESS AGREEMENT dated September __, 2006 between Neose Technologies, Inc. ("Neose") and Auxilium Pharmaceuticals, Inc. ("Auxilium") relating to the property located at 102 Witmer Road, Horsham, Pennsylvania (the "Property"). BACKGROUND Neose is the current owner of the Property, and Auxilium desires to become the lessee of the Property upon its sale to ARE-PA Region No. 6, LLC ("Alexandria"). Simultaneously with the execution hereof, Neose and Alexandria have entered into a Purchase and Sale Agreement and Joint Escrow Instructions ("Agreement of Sale") for the sale and purchase of the Property, and Auxilium and Alexandria have entered into a Lease (the "Lease") for the lease of the Property. The parties anticipate the closing on the sale of the Property pursuant to the Agreement of Sale will occur on or about September __, 2006 (the "Closing"). A condition to Closing is that the Lease has been executed and the commencement date of the term of the Lease will be the date of Closing. Auxilium has requested and Neose has agreed to permit Auxilium to enter the Property and to commence making certain alterations and improvements thereto prior to the date of Closing pursuant to the terms and conditions of this Agreement. In addition, Neose and Auxilium are simultaneously entering into a Post-Closing Property Access Agreement pursuant to which, among other things, Neose shall be permitted to remain in occupancy of certain portion of the Property and Neose and Auxilium shall share certain facilities within the Property ("Post-Closing Agreement"). In consideration of the mutual premises and covenants contained herein and intending to be legally bound hereby, the parties agree as follows: TERMS ACCESS. Activities. Subject to the terms and conditions of this Agreement, Auxilium shall be permitted, with charge, to enter and use the portions of the Property shaded in Schedule 1.1 (the "Access Area") and have access to the equipment in the Access Area (the "Access Equipment") prior to the Closing in order to conduct the activities listed in Sections 1.1.1 and 1.1.2 (collectively, the "Work), all of which shall be performed at the sole cost and expense of Auxilium, during normal business hours, as follows: From and after the date hereof, upon reasonable notice to Neose and without unreasonably interfering with Neose operations, Auxilium may conduct facility touring, walk-down, and engineering surveys, without manipulating (e.g., turning valves or dials, adjusting settings, turning off or on) any equipment absent Neose consent, and may store such equipment as is approved in advance by Neose ("Approved Equipment") and materials approved in advance by Neose ("Approved Materials") in the Access Area, other than in the Pilot Plant, and at 201 Witmer Road, Horsham, Pennsylvania; From and after the later of the date hereof and August 18, 2006, Auxilium may begin engineering modifications, approved in accordance with Section 2.1, consisting of nitrogen supply and distribution piping, local control of gas at fermenter, and potential agitation 8 modifications of fermenter in the Access Area to Access Equipment, bring any additional Approved Materials, into the development areas (outside the Pilot Plant core) as shown in Schedule 1.1, and perform any other modifications that the parties agree to in writing. From and after the later of four (4) business days after the date hereof and August 24, 2006, Auxilium shall have the exclusive use of the cubicles and offices shown in Schedule 1.1.3. From and after the later of the date hereof and September 1, 2006, Auxilium shall have the right to bring Approved Materials into the Pilot Plant and conduct engineering run batch manufacturing in the Expanded Access Area as delineated in Schedule 1.1.4. Interference; Compliance. Auxilium will use commercially reasonable efforts to ensure that neither the Work, the use of Approved Materials nor Auxilium's access to the Property will unreasonably interfere with Neose's operations at the Property or cause any harm or destruction to or contamination of the Property. Neose and Auxilium shall cooperate with each other in order to implement such procedures and protocol as are reasonable or necessary to ensure the safety of each other's personnel and to ensure noninterference with each party's business operations. Auxilium's use and occupancy of the Property, including its use of Approved Materials and the conduct of the Work, shall at all times comply with all applicable laws, regulations, ordinances, safety requirements and SOPs of Neose ("Laws and Requirements"). Except as expressly permitted herein or with the prior written consent of Neose, Auxilium will not bring onto the Property or use any materials other than the Approved Materials. Auxilium and Neose will comply with the procedures agreed upon by the parties. MANNER OF WORK. Auxilium shall take all commercially reasonable precautions to perform all the Work in such a manner to prevent: (i) damage to the Property and the personal property of Neose; (ii) the creation of hazardous or dangerous conditions; (iii) the deposit or release of any hazardous or toxic substances or materials, at, on, about or under the Property; (iv) unreasonable interferences with Neose's normal business operations; and (v) the violation of Neose's safety and security requirements. All Work shall be done in a good and workmanlike manner, in accordance with all applicable Laws and Requirements and in accordance with plans and specifications approved by Alexandria and Neose. Neose agrees that wherever this Agreement requires its approval or consent that its response shall not be unreasonably withheld, conditioned, delayed or denied and that its consent or approval shall be granted so long as Auxilium's actions will not unreasonably interfere with Neose's use and occupancy of the Property or with any equipment other than the Access Equipment and shall not reasonably be anticipated to cause a material adverse affect to the structure or the improvements at the Property or its systems. Auxilium, at its sole costs and expense, shall obtain any and all necessary governmental approvals and permits for the conduct of the Work and Neose, at no expense to it, agrees to cooperate with Auxilium in connection with obtaining any such permits and approvals. In connection with any Work, Auxilium shall not permit the attachment of any mechanic's lien, materialman's lien, or any other lien, claim or encumbrance ("Encumbrance") against the Property. In the event of such Encumbrance, Auxilium shall bear all cost and expense related to the defense or removal of same and indemnify and hold Neose harmless from any actual and documented cost or expense (including reasonable attorneys' fees) which Neose may incur in connection therewith. Prior to performing any Work, Auxilium shall cause its contractors and 9 suppliers to file with the Prothonotary of Montgomery County, Pennsylvania duly executed waivers of mechanic's liens and/or materialman's liens, as applicable. The Access Area shall be made available pursuant to this Agreement to Auxilium on an As-Is, Where-Is basis. Neose shall have no obligation to provide any improvements, alterations or modifications to the Property, nor shall Neose be obligated to provide Auxilium with any allowances for any of the foregoing. Neose shall supply the Access Area with utilities to the extent that any such utilities are currently being provided to the Access Area. In the event Neose removes any fixtures or equipment from the Access Area, Neose shall be responsible, at its sole cost and expense, to repair all damage caused by such removal. RESTORATION. If, for any reason, the Closing under the Agreement of Sale is not consummated on or before September 15, 2006, upon written notice by Neose, Auxilium will vacate the Property within 5 business days. In the event that Auxilium has begun an engineering run when such termination notice is received, Auxilium will vacate the Property within 15 business days. In accordance with such termination notice, Auxilium will restore the Access Area and Access Equipment and all parts thereof to their respective conditions prior to Auxilium's entry, including, but not limited to, removal of all of Auxilium's property, fixtures and equipment and decontamination of the Property and any and all parts thereof. In addition, Auxilium shall decontaminate the Property to remove any contamination of the Property resulting from the Approved Materials and the equipment, fixtures and other property located therein and all surfaces of, on, about or beneath any of the foregoing. If the Work shall necessitate a repair or clean-up, then following Neose's approval of Auxilium's plan to repair and clean-up the Property, Auxilium, under Neose's supervision, shall repair and clean-up the Property to its pre-occupancy condition as determined by Neose in its reasonable discretion. INSURANCE. Auxilium shall, at its expense, maintain or cause its contractors to maintain during the period of access hereunder commercial general liability insurance, including contractual liability insurance and property damage insurance under policies issued by insurers licensed to conduct business in the state wherein the Property is located, with per occurrence limits of not less than $5 Million for bodily injury, or death and damage to or destruction of property (including the loss of use thereof), $5 Million combined aggregate, and workers' compensation at statutory limits. Additionally, Auxilium or its contractors, as applicable, shall provide the following coverages: contractor's pollution liability with limits of $1 Million per occurrence and $2 Million aggregate. Such policies shall name Neose, Alexandria, Alexandria Real Estate Equities, Inc., and its and their respective officers, directors, members, and employees as additional insureds. Auxilium shall deliver to Neose certificates of insurance evidencing such coverage prior to entering upon the Property. Such certificates shall contain a provision that same shall not be cancelled or the coverage materially altered without first giving at least thirty days' prior written notice to Neose. Any policy or policies of fire, extended coverage or similar property insurance, which either party obtains in connection with the Property, shall include a clause or endorsement denying the insurer any rights of subrogation against the other party for all perils covered by such policy. Any provision of this Agreement to the contrary notwithstanding, Neose and Auxilium hereby release the other from any and all liability or responsibility to the other or anyone claiming through or under them by way of subrogation or otherwise (a) from any and all liability for any loss or damage to the property of the releasing party, (b) for any loss or damage that may result, directly or indirectly, from the loss or damage to such property (including rental value and business interruption), and (c) from legal liability for any loss or damage to property 10 (no matter who the owner of the property may be), all to the extent that the releasing party's loss or damage is insured or, if not insured, was insurable under commercially available "special form" property insurance policies, including additional coverages typically obtained by owners and users of comparable facilities, even if such loss or damage or legal liability shall be caused by or result from the fault or negligence of the other party or anyone for whom such party may be responsible and even if the releasing party is self-insured in whole or in part or the amount of the releasing party's insurance is inadequate to cover the loss or damage or legal liability. It is the intention of the parties that Neose and Auxilium shall look solely to their respective insurance carriers for recovery against any such property loss or damage or legal liability, without such insurance carriers having any rights of subrogation against the other party. ELIGIBLE EMPLOYEES. In connection with the transfer of the Property to Auxilium under the Lease and effective as of the Closing, Neose shall make available for hire by Auxilium the employees listed in Schedule 5 (each an "Eligible Employee"). Auxilium shall be permitted to engage the services of any of the Eligible Employees on such terms and conditions as may be agreed by Auxilium and the applicable employee, if any. Except with the prior written consent of Neose, Auxilium shall not, for a period of one year following the Closing, directly or indirectly (other than by general advertising) solicit for employment or hire any person who has been employed by Neose at any time during the one-month period prior to the date hereof, unless such employee is an Eligible Employee or if such employee's employment has been terminated by Neose. The parties agree that the confidentiality provisions of the CDA (as defined in Section 13 below) shall not preclude a party from advising an employee or former employee of Neose of the terms of this Section 5. COOPERATION. Cooperation. Neose and Auxilium shall cooperate with each other in establishing and implementing such procedures and protocol as are necessary or appropriate to ensure the safety of the Work and Auxilium's activities at the Property prior to Closing. Working Committee. Neose and Auxilium hereby establish a working committee ("Working Committee"), which shall be responsible for the cooperation necessary to allow Auxilium to conduct the Work and to protect the Property and Neose employees and for communication and resolution of issues between the parties. The Working Committee shall consist of two representatives who will be authorized to act for the parties hereunder (respectively, "Neose's Representatives" and "Auxilium's Representatives", and together, the "Representatives"). The Representatives shall be available to attend regularly scheduled and special meetings with each other in person or by conference call. It is expected that regular meetings will be held weekly and may also be attended by employees or representatives of either party other than the Representatives. Appointment of Representatives. Auxilium's Representatives will be Ben Del Tito and Michael Cowan, and Neose's Representatives will be H. James White and Hoyt Emmons. Each Party may remove and replace its Representatives on the Working Committee at any time, without cause, upon written notice to the other Party. Each party's Representatives shall have the authority to act on such party's behalf at all times and with respect to issues relating to the performance of the Work and the use and occupancy of the Property by Auxilium prior to Closing. COMMISSIONS. If and when the Lease is fully executed and Closing occurs, Neose shall be responsible for paying Studley, Inc. (Auxilium's broker) and Trammel Crow Company (Neose's 11 Broker) (collectively, "Brokers") a commission pursuant to a separate agreement between such Brokers and Neose. Neose and Auxilium represent and warrant to each other that the Brokers are the sole brokers with whom each has negotiated in bringing about the Lease and each party agrees to indemnify and hold the other harmless from any and all claims of other brokers and expenses in connection therewith arising out of a misrepresentation hereunder. ASSIGNMENT. Auxilium shall not be permitted to assign its rights or obligations hereunder. TERM. This Agreement shall expire and terminate effective as of Closing except with respect to the obligations of the parties set forth in Sections 7, 10 and 11, which shall survive Closing. In the event Closing does not occur on or before September 15, 2006, Neose shall be permitted to terminate this Agreement and all rights of Auxilium in and to the Property upon written notice to Auxilium whereupon Auxilium shall vacate the Property and restore the Access Area, the Expanded Access Area and Access Equipment as provided in Section 3. INDEMNITY. Auxilium shall indemnify, defend and hold Neose free and harmless from and against any and all claims, liabilities, damages, losses, actual and documented costs or expenses (including reasonable attorneys' fees) to the extent arising from Auxilium's activities on the Property; any act or omission of Auxilium or anyone acting by or on behalf of Auxilium at or about the Property in connection with this Agreement or otherwise; any use or the presence at the Property of Approved Materials; and any failure of Auxilium to comply with the terms of this Agreement. Neose 's consent to any Work shall not be a basis of liability to and shall in no way diminish the generality of this indemnity or the scope of any of Auxilium's obligations or covenants contained in this Agreement. Neose shall indemnify, defend and hold Auxilium free and harmless from and against any and all claims, liabilities, damages, losses, actual and documented costs or expenses (including reasonable attorneys' fees) to the extent arising from (i) any claim by a third party alleging injury due to the negligence, gross negligence or willful misconduct of Neose, and (ii) any grossly negligent act or willful misconduct of Neose or anyone acting by or on behalf of Neose at or about the Property. RELEASE. In order to induce Neose to permit Auxilium to access the Property and conduct activities and the Work thereon, Auxilium, on behalf of itself, its officers, employees, representatives, agents and contractors (collectively, "Auxilium Releasors") hereby expressly RELEASE AND FOREVER DISCHARGE Neose, its employees, agents, contractors and representatives (collectively, "Neose Releasees") from any and all expenses, losses, costs, liabilities, claims, causes of action, demands and damages for loss, damage, injury or death to the Neose Releasees, or any of them (except to the extent resulting from the gross negligence or willful misconduct of the Neose Releasees), or damage to the property of Auxilium Releasors, or any of them, arising out of or in connection with the Auxilium's use and occupancy of the Property arising at any time including, but not limited to, the performance of Work on the Property. CONFIDENTIALITY. The parties hereby amend the Confidentiality and Non-Disclosure Agreement between the parties dated as of March 1, 2006 (the "CDA") to extend term of the CDA through the term of this Agreement and the Post-Closing Agreement, and the CDA shall remain in full force and effect throughout the term of this Agreement and the Post-Closing Agreement. Nothing herein shall modify the survival of any provision of the CDA after such term as currently 12 provided therein. This Agreement is subject and subordinate in all respects to the Consent to Property Access Agreements of even date herewith among Alexandria, Neose, and Auxilium. MISCELLANEOUS. This Agreement may be executed in several counterparts, all of which constitute one and the same instrument. This Agreement shall be governed by and construed in accordance with the laws of the Commonwealth of Pennsylvania. The language of this Agreement shall be construed according to its normal and usual meaning and not strictly for or against either Neose or Auxilium. The rule of construction which allows a court to construe a document more strictly against its author shall not govern the interpretation of this Agreement. If any provision of this Agreement, or its application to any situation, shall be invalid or unenforceable to any extent, the remainder of this Agreement, or the application thereof to situations other than as to which it is invalid or unenforceable, shall not be affected thereby, and every provision of this Agreement shall be valid and enforceable to the fullest extent permitted by law. This Agreement, together with the Post-Closing Agreement and the CDA, constitutes the entire agreement, and supersedes the letter agreement dated July 26, 2006, between the parties relating to the subject matter hereof, and may be amended only by written agreement of the parties. No representations, inducements, promises or agreements, oral or otherwise, between Neose or Auxilium or any of their respective brokers, employees or agents, not embodied herein, shall be of any force or effect. This Agreement shall be binding upon and shall inure to the benefit of the parties hereto, their heirs, executors, administrators, successors and permitted assigns. Notices. All notices provided for or permitted under this Agreement shall be in writing and shall be: (i) delivered personally; (ii) sent by facsimile with return facsimile confirmation; (iii) sent by commercial overnight courier with written verification of receipt; or (iv) sent by certified or registered U.S. mail, postage prepaid and return receipt requested, to the party to be notified, at the address for such party set forth below, or at such other address of which such party has provided notice in accordance with the provisions of this paragraph: To Auxilium: Auxilium Pharmaceuticals, Inc. Attn: General Counsel 40 Valley Stream Parkway Malvern, PA 19355 Fax: (484) 321-2208 To Neose: Neose Technologies, Inc. Attn: General Counsel 102 Witmer Road Horsham, PA 19044 13 Notices shall be deemed effective (i) if delivered in person, when delivered; (ii) if delivered by facsimile, on the date of receipt of facsimile confirmation; (iii) if delivered by commercial overnight courier, on the date of written verification of receipt; or (iv) if delivered by certified or registered U.S. mail, five business days after deposit in the mail. Neose and Auxilium agree that time is of the essence of this Agreement. 14 IN WITNESS WHEREOF, Neose and Auxilium, intending to be legally bound hereby, have signed this Agreement as of the day and year first above written. Neose Technologies, Inc. Auxilium Pharmaceuticals, Inc. By: By: --------------------------------- ------------------------------------ Name: Name: ------------------------------- ---------------------------------- Title: Title: ------------------------------ --------------------------------- 15 SCHEDULE 1.1 Access Area (FLOOR PLAN) 102 Witmer - Pre-Close Agreement 16 Schedule 1.1.3 Cubicles and Offices (FLOOR PLAN) 102 Witmer - Pre-Close Agreement 17 Schedule 1.1.4 Expanded Access Area (FLOOR PLAN) 102 Witmer - Pre-Close Agreement 18 Schedule 5 Eligible Employees 19 POST-CLOSING PROPERTY ACCESS AGREEMENT THIS POST-CLOSING PROPERTY ACCESS AGREEMENT, dated September __, 2006, but intended to be effective as of (and expressly conditioned on) the Closing (as defined herein), is between Neose Technologies, Inc. ("Neose") and Auxilium Pharmaceuticals, Inc. ("Auxilium") relating to the property located at 102 Witmer Road, Horsham, Pennsylvania (the "Property"). BACKGROUND Neose is the current owner of the Property, and Auxilium desires to become the lessee of the Property upon its sale to ARE-PA Region No. 6, LLC ("Alexandria"). Simultaneously with the execution hereof, Neose and Alexandria have entered into a Purchase and Sale Agreement and Joint Escrow Instructions ("Agreement of Sale") for the sale and purchase of the Property, and Auxilium and Alexandria have entered into a Lease (the "Lease") for the lease of the Property. The parties anticipate the closing on the sale of the Property pursuant to the Agreement of Sale will occur on or about September __, 2006 (the "Closing"). Pursuant to a Pre-Closing Property Access Agreement of even date herewith ("Pre-Closing Agreement") between Auxilium and Neose, Neose has agreed to permit Auxilium to enter the Property and to commence making certain alterations and improvements thereto prior to the date of Closing. In addition, Neose has requested and Auxilium has agreed that, following the Closing, Neose shall be permitted to remain in occupancy of certain portions of the Property and that Neose and Auxilium shall share certain facilities within the Property in accordance with the terms and conditions of this Agreement. TERMS In consideration of the mutual promises and covenants contained herein and intending to be legally bound hereby, the parties agree as follows: NEOSE ACCESS. Spaces. Upon Closing and consummation of the Lease, Auxilium hereby gives to Neose from the date of the Closing through February 28, 2007: (a) the exclusive right to use and occupy the laboratory and office areas of the Property designated as Neose Space in Schedule 1.1 ("Neose Space"), (b) the non-exclusive right in common with Auxilium to use and occupy the areas of the Property designated as Shared Space in Schedule 1.1 ("Shared Space"), (c) the non-exclusive right in common with Auxilium to use the Property's parking lot reasonably sufficient to accommodate Neose's access hereunder ("Parking Space"), (d) the non-exclusive right in common with Auxilium to use all corridors and other means of access to the Neose Space, the Shared Space and the Parking Space (together with the Neose Space, the Shared Space and the Parking Space, the "Spaces") and (e) the non- exclusive right in common with Auxilium to use the fax machines and copiers conveyed to Alexandria pursuant to the Agreement of Sale, and which are being leased by Alexandria to Auxilium pursuant to the Lease. The foregoing rights to use and occupy the Spaces shall be free of any and all charges. Each party agrees that access to the Shared Space by both parties may require schedules to be coordinated and/or changed from time to time to enable each party to carry out its regular business objective. Neose and Auxilium shall endeavor to have a working schedule in place by the Closing. Each party agrees that it shall provide notice to the other as soon as it is determined that a reasonable change to an agreed schedule is required. All schedules and reasonable changes to existing schedules shall be coordinated through the Representatives described below. The Spaces will be made 20 available to Neose on an "As-Is, Where-Is" basis, without representation or warranty of any kind and Neose expressly accepts the Spaces on such basis. Compliance. Neose will use reasonable commercial efforts to ensure that neither Neose's access to the Property, the occupancy of the Spaces, nor the conduct of its operations will interfere with Auxilium's operations at the Property or cause any harm or destruction to or contamination of the Property. Auxilium will use reasonable commercial efforts to ensure that Neose will have the right of quiet enjoyment of the Spaces and will be able to conduct its operations. Neose's use and occupancy of the Property shall at all times comply with all applicable laws, regulations, ordinances, safety requirements and SOPs of Auxilium ("Laws and Requirements"). Auxilium and Neose will comply with all procedures agreed upon by the parties. Alterations. Neose shall not make any installations, improvements, additions, alterations, or attachments to the Spaces without the prior consent of Auxilium, such consent not to be unreasonably withheld or delayed. Neose, at its sole cost and expense, shall immediately repair any damage caused to the Spaces by Neose, its employees, invitees or contractors following the Closing. Calibrations. Between the Closing and September 15, 2006, Neose and its calibration vendor, Integrated Service Solutions, shall have the right of access to the pilot plant, upon reasonable notice and during normal business hours, for the purpose of executing terminal calibrations and other calibrations due on Conveyed Equipment. COOPERATION. Cooperation. Neose and Auxilium shall cooperate with each other in order to agree upon and implement such reasonable procedures and reasonable protocol as are reasonably necessary to ensure the safety of each other's personnel and to ensure noninterference with each party's business operations. It is understood that, during the period of this Agreement, certain equipment designated as Shared Equipment in Schedule 2.1 will be shared by the parties. The parties agree to cooperate with each other with respect to the use of the Shared Equipment and any issues with respect to the use of the Shared Equipment shall be referred to the Working Committee (as defined below). It is also understood that, until Neose vacates the Property, Auxilium shall have the right to use up to fifty (50) lines of the existing telephone system serving the Property. Facility Employees. Neose and Auxilium agree that the facility employees listed in Schedule 2.2 (each a "Facility Employee") shall, regardless of which party employs them, continue to work together in an integrated manner to perform their current job duties of maintaining the Property for the benefit of both Neose and Auxilium and the Property, 201 Witmer Road, and 102 Rock Road, Horsham, PA. During the thirty-day period commencing on the date of Closing, to the extent he remains an employee of Neose, Neose will, upon reasonable notice and subject to his availability, make Chris Garges available to Auxilium to answer questions and otherwise provide information about the use of the Property, up to an aggregate maximum of 20 hours. Working Committee. Neose and Auxilium hereby establish a working committee ("Working Committee"), which shall be responsible for the cooperation necessary to allow Auxilium and Neose to protect their employees and conduct their operations to manage the Facility Employees, and for communication and resolution of issues between the parties. 21 The Working Committee shall consist of two representatives who will be authorized to act for the parties hereunder (respectively, "Neose's Representatives" and "Auxilium's Representatives", and together, the "Representatives"). The Representatives shall be available to attend regularly scheduled and special meetings with each other in person or by conference call. It is expected that regular meetings will be held weekly and may also be attended by employees or representatives of either party other than the Representatives. Appointment of Representatives. Auxilium's Representatives will be Ben Del Tito and Michael Cowan, and Neose's Representatives will be James White and Hoyt Emmons. Each Party may remove and replace its Representatives on the Working Committee at any time, without cause, upon written notice to the other Party. Each party's Representatives shall have the authority to act on such party's behalf at all times and with respect to issues relating to this Agreement. Dispute. In the event the Working Committee shall fail to mutually resolve any matter it is responsible for hereunder, Neose and Auxilium agree to submit such matter to the senior management of each party for mutual resolution. In the event the senior management shall fail to mutually resolve such matter, Neose and Auxilium agree to submit such matter pursuant to the Expedited Procedures provisions of the Arbitration Rules for the Real Estate Industry of the AAA (presently Rules 56 through 60); provided, however, that with respect to any such arbitration, (i) the list of arbitrators referred to in Rule 57 shall be returned within five (5) business days from the date of mailing, (ii) the parties shall notify the AAA, by telephone of any objections to the arbitrator appointed, within four (4) days after such appointment, and will have no right to object if the arbitrator so appointed was on the list submitted by the AAA and was not objected to in accordance with Rule 57, (iii) the notice of hearing referred to in Rule 58 shall be four (4) days in advance of the hearing, (iv) the hearing shall be held within seven (7) days after the appointment of the arbitrator, and (v) the arbitrator shall have no right to award damages. INSURANCE. Neose shall, at its expense, maintain or cause its contractors to maintain during the period of access hereunder commercial general liability insurance, including contractual liability insurance and property damage insurance under policies issued by insurers licensed to conduct business in the state wherein the Property is located, with per occurrence limits of not less than $5 Million for bodily injury, or death and damage to or destruction of property (including the loss of use thereof), $5 Million combined aggregate, and workers' compensation at statutory limits. Such policies shall name Auxilium, Alexandria, Alexandria Real Estate Equities, Inc., and its and their respective officers, directors, members, and employees as additional insureds. Neose shall deliver to Auxilium and Alexandria certificates of insurance evidencing such coverage prior to entering upon the Property. Such certificates shall contain a provision that same shall not be cancelled or the coverage materially altered without first giving at least thirty days' prior written notice to Auxilium and Alexandria. Any policy or policies of fire, extended coverage or similar property insurance, which either party obtains in connection with the Property, shall include a clause or endorsement denying the insurer any rights of subrogation against the other party for all perils covered by such policy. Any provision of this Agreement to the contrary notwithstanding, Neose and Auxilium hereby release the other from any and all liability or responsibility to the other or anyone claiming through or under them by way of subrogation 22 or otherwise (a) from any and all liability for any loss or damage to the property of the releasing party, (b) for any loss or damage that may result, directly or indirectly, from the loss or damage to such property (including rental value and business interruption), and (c) from legal liability for any loss or damage to property (no matter who the owner of the property may be), all to the extent that the releasing party's loss or damage is insured or, if not insured, was insurable under commercially available "special form" property insurance policies, including additional coverages typically obtained by owners and users of comparable facilities, even if such loss or damage or legal liability shall be caused by or result from the fault or negligence of the other party or anyone for whom such party may be responsible and even if the releasing party is self-insured in whole or in part or the amount of the releasing party's insurance is inadequate to cover the loss or damage or legal liability. It is the intention of the parties that Neose and Auxilium shall look solely to their respective insurance carriers for recovery against any such property loss or damage or legal liability, without such insurance carriers having any rights of subrogation against the other party. INDEPENDENT CONTRACTORS. Neose and Auxilium are independent contractors hereunder and, except as otherwise provided herein, shall conduct their respective businesses as they may determine, and neither party, nor any officer, employee or agent of either party, shall have the authority to bind the other party in any way whatsoever, or to accept service of legal process for and on behalf of the other party pursuant to this Agreement. Neither Neose nor Auxilium shall be deemed in any way or for any purpose, to have become, by the execution of this Agreement or any action taken hereunder, a partner of the other party in its business or a joint venturer or a member of a joint enterprise with the other party. TECHNICAL INFORMATION. Pursuant to the Agreement of Sale, Neose is conveying to Alexandria, to the extent available and in its possession, Neose's non-proprietary standard operating procedures specifically relating to the Property and the maintenance of the personal property being conveyed by Neose to Alexandria at Closing pursuant to the Agreement of Sale ("Conveyed Equipment"), validation protocols for all Conveyed Equipment and facility systems, and equipment turnover packages and equipment history files relating to the Conveyed Equipment and facility systems ("Technical Information"). Neose agrees that Alexandria may share the Technical Information with Auxilium. Auxilium agrees that, during the term of this Agreement, the Technical Information will be retained at the Property and that Neose may make copies of any or all of the Technical Information. Neose agrees that it shall not remove any of the Conveyed Equipment or Technical Information (except as necessary to make copies). Neose further agrees that, upon expiration or earlier termination of this Agreement, Neose shall leave all the Conveyed Equipment and Technical Information (other than copies made by Neose) at the Property. Neose acknowledges that, to the extent Auxilium supplements or modifies the Technical Information after the Closing, Neose will have no rights with respect to such supplemental or modified Technical Information. 23 WAREHOUSE FACILITY. Subject to Neose's landlord's consent, and a separate agreement among such landlord, Auxilium and Neose, Neose will assign or sublet the warehouse space at 201 Witmer Road, Horsham, PA to Auxilium effective as of the Closing for the remainder of the current lease term, at the same current lease rates and charges, and Auxilium will allow Neose to occupy a portion of the warehouse space as designated in Schedule 6, free of charge, for the remainder of the current lease term. Within two (2) days from the date hereof, Neose shall request the landlord of 201 Witmer Road to consent to the foregoing described lease assignment or sublease. SURRENDER. As of February 28, 2007, Neose shall (i) vacate and surrender the Spaces to Auxilium in broom clean condition, (ii) remove all of Neose's property, fixtures and equipment (including the components of the existing telephone system not included as part of the Conveyed Equipment other than cabling, wires and connections within walls, above ceilings or beneath floors) from the Spaces, (iii) restore any damage caused by the removal of any property, fixtures and equipment of Neose, (iv) decontaminate, repair, or clean-up the Spaces to remove any contamination from the Spaces resulting from Neose's operations following Closing to standards reasonably acceptable to Auxilium and (v) remove the exterior hazardous materials shed from the Property and any contamination resulting from the shed following Closing to standards reasonably acceptable to Auxilium. ASSIGNMENT. Auxilium and Neose shall not be permitted to assign their rights or obligations hereunder. TERM. This Agreement shall expire and terminate effective as of February 28, 2007, except with respect to the obligations of the parties set forth in paragraphs 4, 6, 8, 9, and 11 which shall survive termination. If Neose fails to vacate the Property by 12:00 a.m. on March 1, 2007 for any reason, then for each and every day that Neose fails to so vacate, it shall pay to Auxilium the sum of $1,000 per day. This charge shall not limit Auxilium's right to seek such other remedies as may be available to Auxilium either at law or in equity. MECHANIC'S LIENS. Neose shall not cause or permit the attachment of any mechanic's lien, materialman's lien, or any other lien, claim or encumbrance ("Encumbrance") against the Property. In the event of such Encumbrance, Neose shall bear all cost and expense related to the defense or removal of same and indemnify and hold Auxilium harmless from any actual and documented cost or expense (including reasonable attorneys' fees) which Auxilium may incur in connection therewith. INDEMNITY. Neose shall indemnify, defend and hold Auxilium free and harmless from and against any and all claims, liabilities, damages, losses, actual and documented costs or expenses (including reasonable attorneys' fees) to the extent arising from Neose's activities on the Property; any act or omission of Neose or anyone acting by or on behalf of Neose at or about the Property in connection with this Agreement or otherwise; and any failure of Auxilium to comply with the terms of this Agreement. Auxilium shall indemnify, defend and hold Neose free and harmless from and against any and all claims, liabilities, damages, losses, actual and documented costs or expenses (including reasonable attorneys' fees) to the extent arising from (i) any claim by a third party alleging injury due to the negligence, gross negligence or willful misconduct of Auxilium, and 24 (ii) any grossly negligent act or willful misconduct of Auxilium or anyone acting by or on behalf of Auxilium at or about the Property. RELEASE. In order to induce Auxilium to permit Neose to access the Property, Neose, on behalf of itself, its officers, employees, representatives, agents and contractors (collectively, "Neose Releasors") hereby expressly RELEASE AND FOREVER DISCHARGE Auxilium, its employees, agents, contractors and representatives (collectively, "Auxilium Releasees") from any and all expenses, losses, costs, liabilities, claims, causes of action, demands and damages for loss, damage, injury or death to the Auxilium Releasees, or any of them (except to the extent resulting from the gross negligence or willful misconduct of the Auxilium Releasees), or damage to the property of Neose Releasors, or any of them, arising out of or in connection with the Neose's use and occupancy of the Property. SERVICE CONTRACTS. As of Closing, Neose (i) hereby assigns, transfers and sets over unto Auxilium, and as of Closing Auxilium hereby accepts, all Neose's rights, title and interest in and to those certain contracts listed in Part A of Schedule 13.1, which Contracts pertain solely to the Property or Conveyed Equipment and are immediately assignable ("Assignable Contracts"), and (ii) will cooperate with Auxilium to obtain the consent of the other party to, and assign, transfer, and set over to Auxilium the contracts listed in Part B of Schedule 13.1, which contracts pertain solely to the Property or Conveyed Equipment and require consent for assignment ("Consent Contracts" and together with the Assignable Contracts, the "Contracts"). From and after the Closing, Neose and Auxilium will use commercially reasonable efforts to arrange for the transfer to Auxilium the rights and obligations under the contracts listed in Part C of Schedule 13.1, which rights and obligations relate solely to the Property or Conveyed Equipment ("Combined Contracts"). Neose represents and warrants to Auxilium that: (a) the Contracts have not been assigned previously and are not subject to any lien or encumbrance, (b) all sums required to be paid as of the date hereof under the Contracts have been paid, and (c) the copies of the Contracts previously provided to Auxilium are true correct and complete and constitute the entire agreement between Neose and the respective contractors under the Contracts. Neose shall be responsible for the observance and performance of all its agreements and obligations under the Contracts arising prior to Closing. Auxilium hereby assumes and agrees to perform all of the covenants, agreements and obligations of Neose arising out of or relating to the Contracts which first arise and relate to the period from and after the Closing. Neose shall to the extent permitted by law, defend, protect, indemnify and save harmless Auxilium from and against any and all liabilities, suits, actions, losses, damages, costs and expenses, including without limitation counsel fees, suffered or incurred by Auxilium resulting from or relating to any failure by Neose to observe or perform any of its agreements or obligations under the Contracts prior to Closing. Auxilium shall defend, protect, indemnify and save harmless Neose from and against any and all liabilities, suits, actions, losses, damages, costs and expenses, including without limitation counsel fees, suffered or incurred by Neose resulting from or relating to any failure 25 by Auxilium to observe or perform any of its agreements or obligations under the Contracts on or after the Closing. At Closing, the expenses relating to the Contracts shall be prorated between Auxilium and Neose and Auxilium shall pay to Neose the amount that Neose has paid prior to Closing for post-Closing time periods. MISCELLANEOUS. This Agreement may be executed in several counterparts, all of which constitute one and the same instrument. This Agreement shall be governed by and construed in accordance with the laws of the Commonwealth of Pennsylvania. The language of this Agreement shall be construed according to its normal and usual meaning and not strictly for or against either Neose or Auxilium. The rule of construction which allows a court to construe a document more strictly against its author shall not govern the interpretation of this Agreement. If any provision of this Agreement, or its application to any situation, shall be invalid or unenforceable to any extent, the remainder of this Agreement, or the application thereof to situations other than as to which it is invalid or unenforceable, shall not be affected thereby, and every provision of this Agreement shall be valid and enforceable to the fullest extent permitted by law. This Agreement, together with the Pre-Closing Agreement and the Confidentiality and Nondisclosure Agreement dated March 1, 2006, as amended by the Pre-Closing Agreement, constitutes the entire agreement, and supersedes the letter agreement dated July 26, 2006, between the parties relating to the subject matter hereof, and may be amended only by written agreement of the parties. No representations, inducements, promises or agreements, oral or otherwise, between Neose or Auxilium or any of their respective brokers, employees or agents, not embodied herein, shall be of any force or effect. This Agreement is subject and subordinate in all respects to the Consent to Property Access Agreements of even date herewith among Alexandria, Neose, and Auxilium. This Agreement shall be binding upon and shall inure to the benefit of the parties hereto, their heirs, executors, administrators, successors and permitted assigns. Notices. All notices provided for or permitted under this Agreement shall be in writing and shall be: (i) delivered personally; (ii) sent by facsimile with return facsimile confirmation; (iii) sent by commercial overnight courier with written verification of receipt; or (iv) sent by certified or registered U.S. mail, postage prepaid and return receipt requested, to the party to be notified, at the address for such party set forth below, or at such other address of which such party has provided notice in accordance with the provisions of this paragraph: 26 To Auxilium: To Auxilium: Auxilium Pharmaceuticals, Inc. Attn: General Counsel 40 Valley Stream Parkway Malvern, PA 19355 Fax: (484) 321-2208 To Neose: Neose Technologies, Inc. Attn: General Counsel 102 Witmer Road Horsham, PA 19044 Notices shall be deemed effective (i) if delivered in person, when delivered; (ii) if delivered by facsimile, on the date of receipt of facsimile confirmation; (iii) if delivered by commercial overnight courier, on the date of written verification of receipt; or (iv) if delivered by certified or registered U.S. mail, five business days after deposit in the mail. Neose and Auxilium agree that time is of the essence of this Agreement. 27 IN WITNESS WHEREOF, Neose and Auxilium, intending to be legally bound hereby, have signed this Agreement as of the day and year first above written. Neose Technologies, Inc. Auxilium Pharmaceuticals, Inc. By: By: ------------------------------ ------------------------------------ Name: Name: ---------------------------- ---------------------------------- Title: Title: --------------------------- --------------------------------- Schedule 1.1 Neose Space SCHEDULE 1.1 (FLOOR PLAN) 102 Witmer - Post-Close Agreement 29 Schedule 2.1 Shared Equipment SCHEDULE 2.1 CONFIDENTIAL WITMER ROAD PROPERTY - SHARED ASSETS
FAS EQUIPMENT FAS SYSTEM # TAG # TAG # ACQ DATE VENDOR DESCRIPTION LOCATION SERIAL NUMBER - -------- --------- ----- ---------- ----------------- --------------------------------------- -------- -------------- 729 M-01 00107 4/24/2000 Fisher Scientific Microscope-Zeiss-Axiostar Lab 1 33485 N/A VT-116 Mini Vortexer Lab 1 2-375976 1,576 KF-02 01078 10/23/2003 Fisher Scientific KFD Titrino 758/B-20 WR LAB 9 10576598 527 ST01 00958 Lunaire Environmental-(4) stability chambers WR LAB 9 Neose # ST 01 537 ST02 00957 Lunaire Environmental- see # 527 notes WR LAB 9 Neose # ST 02 536 ST03 00956 Lunaire Environmental- see # 527 notes WR LAB 9 Neose # ST 03 528 ST04 00955 Lunaire Environmental- see # 527 notes WR LAB 9 Neose # ST 04 1,695 ST05 01164 4/30/2004 Fisher -20 degree C, 208V general purpose free WR Lab 9 P250-104110-RO 1,699 ST06 01163 4/30/2004 Fisher Scientific Ultima II SI Series ultralow-temp freez WR Lab 9 R220-208039-RO 2,191 ST07 01432 4/30/2005 Fisher Scientific 32 cu ft Revco Environmental Chamber QC lab 31958
Page 1 of 1 Schedule 2.2 "Facility Employee" Walter Waldspurger Terry White Robert Livezey Steven Pinkney Richard Faust Joseph Engart Harry Santoo Aurelia Colding 31 Schedule 6 Warehouse Facility (FLOOR PLAN) 201 Witmer - Post-Close Agreement 32 SCHEDULE 13.1 SERVICE CONTRACTS A. Assignable Contracts are held with the following vendors: - AT Chadwick Service Company+ - Brickman Group - Critical Cleaning, Inc. - Electronic Security Corp. - Lancer USA+ - Neu-Ion - Stericycle - Steris B. Consent Contracts are held with the following vendors: - Allied Waste/BFI - Johnson Controls+ C. Combined Contracts are held with the following vendors: - Agilent+* - Alfa Laval - Beckman Coulter+* - GE Analytical Instruments, Inc.+ - Integrated Service Solutions - JC Ehrlich Co., Inc. - Klenzoid Water Treatment+ - Ransome - Thermo Electron Corporation+ * Consent required for assignment. + The agreements with these vendors have been prepaid in full or in part and a pro-ration must be made upon the transfer of assets pursuant to the Agreement.
EX-99.1 5 w24742exv99w1.txt PRESS RELEASE DATED SEPTEMBER 5, 2006 Exhibit 99.1 NEOSE TECHNOLOGIES ANNOUNCES SALE OF WITMER ROAD FACILITY IMPLEMENTS HEADCOUNT REDUCTION Horsham, PA, September 5, 2006 -- Neose Technologies, Inc. (Nasdaq GM: NTEC) today announced that it has entered into an agreement to sell, for approximately $21 million, the 50,000 square foot facility containing its pilot manufacturing plant and current corporate headquarters ("Witmer Road Facility") located in Horsham, Pennsylvania, to a public real estate investment trust. The Company plans to relocate its corporate headquarters to its leased facility in Horsham within six months. Contemporaneously with the sale of the Witmer Road Facility, the Company is reducing the size of its workforce by approximately 25%. Some of the affected employees have been involved in the operation of the pilot plant and are being offered employment by the new lessee of the facility. Upon closing of the sale of the Witmer Road Facility, which is expected to occur by the end of the week, the Company will realize, net of fees and expenses, proceeds of approximately $19.5 million. In connection with the closing, the Company will repay all outstanding debt associated with the facility of approximately $9.7 million, which includes accrued interest and prepayment penalties. This repayment eliminates the requirement under our term loan with a bank to maintain a minimum cash and short-term investments balance. The remaining net proceeds of approximately $9.8 million will be used to further the Company's research and clinical development objectives and to fund capital expenditures associated with consolidation of operations if such expenditures cannot be financed through the issuance of new debt. The Company will consolidate its operations in its adjacent, leased 40,000 square foot facility in Horsham, which currently houses approximately half of its employees. The Company expects to spend approximately $3.5 million through the first quarter of 2007 to construct additional laboratory and office space in the leased facility. The Company will continue to occupy portions of the Witmer Road Facility until these renovations are complete, which is expected to be by February 2007. NEOSE TECHNOLOGIES, INC. PAGE 2 "The sale of the Witmer Road Facility is strategically important to Neose. It immediately provides a non-dilutive source of capital and will reduce our operating expenses," said George J. Vergis, Ph.D., Neose president and chief executive officer. "The elimination of the positions of dedicated and talented employees is extremely difficult, and we are grateful for the important contributions they have made. We are heartened by the fact that some of these employees will remain in the facility as employees of the new lessee," continued Vergis. After achieving the full benefits in the fourth quarter of 2006 of the facility sale, debt repayment, and workforce reduction, the Company expects to realize annualized savings of between $6 million and $8 million. Net cash utilization for the second half of 2006 is expected to total approximately $8 million to $9 million, which includes the net cash effect of the facility sale, the construction costs in the leased facility, and employee severance and retention costs, compared to net cash utilization during the first half of 2006 of approximately $16.4 million. The Company expects most of the $1 million of employee severance and retention costs will be reflected in its operating results during the third quarter of 2006. The Company expects to recognize a gain from the sale of the facility of approximately $7.5 million, most of which will be reflected in its operating results during the third quarter of 2006. CONFERENCE CALL The Company will host a conference call at 11:00 a.m. (EDT) on Tuesday, September 5, to discuss these actions. The dial-in number for domestic callers is (800) 289-0493. The dial-in number for international callers is (913) 981-5510. A replay of the call will be available for 7 days beginning approximately three hours after the conclusion of the call. The replay number for domestic callers is (888) 203-1112 using the passcode 6408454. The replay number for international callers is (719) 457-0820, also using the passcode 6408454. Live audio of the conference call will be simultaneously broadcast over the Internet through First Call Events, which can be accessed via the following link: http://phx.corporate-ir.net/phoenix.zhtml?c=60494&p=irol-calendar To listen to the live call, please go to the web site at least fifteen minutes early to register, download, and install any necessary audio software. For those who cannot listen to the live broadcast, a replay will be available shortly after the call. The call will also be available on the Investor Relations/Audio Archives page of the Neose website at www.neose.com. ABOUT NEOSE Neose Technologies, Inc. is a clinical-stage biopharmaceutical company focused on the development of next-generation therapeutic proteins that are competitive with best-in-class protein drugs currently on the market, on its own and through strategic partnerships. The lead candidates in its pipeline, NE-180 for use in the treatment of chemotherapy-induced anemia and anemia associated with chronic renal failure and GlycoPEG-GCSF for chemotherapy-induced neutropenia, target markets with aggregate sales in excess of $14 billion. Neose expects to commence Phase II for NE-180 in a Western European country in the fourth quarter of 2006. Neose expects that its partner for GlycoPEG-GCSF, BioGenerix AG, will commence Phase I in a Western European country in the third quarter of 2006. NEOSE TECHNOLOGIES, INC. PAGE 3 CONTACTS: NEOSE TECHNOLOGIES, INC. A. Brian Davis Sr. Vice President and Chief Financial Officer Barbara Krauter Manager, Investor Relations (215) 315-9000 E-mail: info@neose.com For more information, please visit www.neose.com. Neose "Safe Harbor" Statement under the Private Securities Litigation Reform Act of 1995: Statements in this press release regarding our business that are not historical facts, including, but not limited to, statements regarding the sale of our Witmer Road facility and its financial impact, the expense and timing of consolidating our operations in our leased facility, our restructuring, and the timing and amount of restructuring charges that we expect to incur in connection with the restructuring are "forward-looking statements" that involve risks and uncertainties, including without limitation the risk that the closing of the facility sale will not occur in the timeframe anticipated, or at all, the risk that we will incur unexpected charges and/or delays in connection with the consolidation of operations to our leased facility, and the risk that we will incur unexpected charges or will have unexpected expenditures related to the restructuring upon the completion of further analysis with respect to the restructuring generally and our assets specifically. For a discussion of these and additional risks and uncertainties, any of which could cause our actual results to differ from those contained in the forward-looking statement, see the section of Neose's Annual Report on Form 10-K for the year ended December 31, 2005, entitled "Factors Affecting the Company's Prospects" and discussions of potential risks and uncertainties in Neose's subsequent filings with the SEC.
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