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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 LPE+MDtT2wAC9AKCzTNKMY/1Ud/g9go5qMiU0F3IPKdT4B2IG37fCa6KRQHjeeR5
 9ZrISpcvt7m9IEdWCzMIWg==

<SEC-DOCUMENT>0000912057-00-007905.txt : 20000223
<SEC-HEADER>0000912057-00-007905.hdr.sgml : 20000223
ACCESSION NUMBER:		0000912057-00-007905
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20000208
ITEM INFORMATION:		
FILED AS OF DATE:		20000222

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SEPRACOR INC /DE/
		CENTRAL INDEX KEY:			0000877357
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				222536587
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		
		SEC FILE NUMBER:	000-19410
		FILM NUMBER:		550386

	BUSINESS ADDRESS:	
		STREET 1:		111 LOCKE DR
		CITY:			MARLBOROUGH
		STATE:			MA
		ZIP:			01757
		BUSINESS PHONE:		5084816700
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<DESCRIPTION>8-K
<TEXT>

<PAGE>

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                              --------------------

                                    FORM 8-K

                                 CURRENT REPORT
                       PURSUANT TO SECTION 13 OR 15(d) OF
                       THE SECURITIES EXCHANGE ACT OF 1934

       Date of Report (Date of earliest event reported): February 8, 2000

                                  SEPRACOR INC.
             (Exact name of registrant as specified in its charter)

<TABLE>
<CAPTION>

  <S>                                      <C>                            <C>
            DELAWARE                                0-19410                           22-2536587
  -------------------------------          ------------------------       ---------------------------------
  (State or other jurisdiction of          (Commission File Number)       (IRS Employer Identification No.)
           incorporation)


          111 Locke Drive
          Marlborough, MA                                                               01757
  -------------------------------                                         -----------------------------------
  (Address of principal executive                                                     (Zip Code)
              offices)

</TABLE>


       Registrant's telephone number, including area code: (508) 481-6700

                                       N/A
          -------------------------------------------------------------
          (Former name or former address, if changed since last report)


<PAGE>


Item 5.  OTHER EVENTS.

         As of February 8, 2000, Sepracor Inc. had converted $96.4 million 6.25%
Convertible Subordinated Debentures Due 2005 (the "Debentures") and $93 million
Debentures were still outstanding. Costs related to the conversion of the
Debentures, including pre-paid interest, premiums and other costs, were $7.5
million.


<PAGE>


                                    SIGNATURE

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

Date:  February 22, 2000                    SEPRACOR INC.
                                              (Registrant)

                                              By: /s/ Robert F. Scumaci
                                                  -----------------------
                                                  Robert F. Scumaci
                                                  Senior Vice President,
                                                  Finance and Administration


</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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