SEC FILE NUMBER
                                                                     811-6346

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549

                                   FORM 12B-25

                           NOTIFICATION OF LATE FILING

(Check One):   [ ] Form 10-KSB   [ ] Form 20-F    [ ] Form 11-K    [ ] Form 10-Q
               [ ] Form 10-D     [X] Form N-SAR   [ ] Form N-CSR

For Period Ended: October 31, 2006

[ ] Transition Report on Form 10-K
[ ] Transition Report on Form 20-F
[ ] Transition Report on Form 11-K
[ ] Transition Report on Form 10-Q
[ ] Transition Report on Form N-SAR

For the Transition Period Ended: ____________________________________

  Read Instruction (on back page) Before Preparing Form. Please Print or Type.

     NOTHING IN THIS FORM SHALL BE CONSTRUED TO IMPLY THAT THE COMMISSION HAS
VERIFIED ANY INFORMATION CONTAINED HEREIN.

If the notification relates to a portion of the filing checked above, identify
the item(s) to which the notification relates: _________________________________

PART I - REGISTRANT INFORMATION

Morgan Stanley Quality Municipal Investment Trust
Full Name of Registrant

- ---------------------------------------
Former Name if Applicable

1221 Avenue of the Americas
Address of Principal Executive Office (Street and Number)

New York, New York  10020
City, State and Zip Code



                                     PART II
                             RULE 12B-25 (B) AND (C)

     If the subject report could not be filed without unreasonable effort or
expense and the registrant seeks relief pursuant to Rule 12b-25(b), the
following should be completed. (Check box if appropriate).

     (a)  The reasons described in reasonable detail in Part III of this form
          could not be eliminated without unreasonable effort or expense;

[X]  (b)  The subject annual report, semi-annual report, transition report on
          Form 10-KSB, Form 20-F, Form 11-K, Form N-SAR or Form N-CSR, or
          portion thereof, will be filed on or before the fifteenth calendar day
          following the prescribed due date; or the subject quarterly report or
          transition report on Form 10-Q or subject distribution report on Form
          10-D, or portion thereof, will be filed on or before the fifth
          calendar day following the prescribed due date; and

     (c)  The accountant's statement or other exhibit required by Rule 12b-25(c)
          has been attached if applicable.

                                    PART III
                                    NARRATIVE

     State below in reasonable detail why Forms 10-KSB, 20-F, 11-K, 10-Q, 10-D,
N-SAR, N-CSR, or the transition report or portion thereof, could not be filed
within the prescribed time period.

As a result of a recent determination that certain transfers of municipal
securities by the Trust, previously accounted for as sales, do not qualify for
sale treatment and should be accounted for as secured borrowings. The Trust is
not able to finalize its financial statements for a timely filing of its Form
N-SAR without unreasonable effort or expense. Upon resolution of this matter
Deloitte and Touche LLP, the Trust's independent registered public accounting
firm, will complete its audit. The Trust's Form N-SAR will be completed and
filed with the Securities and Exchange Commission as soon as practicable.

                                     PART IV
                                OTHER INFORMATION

     (1) Name and telephone number of person to contact in regard to this
notification

                           
Francis J. Smith       201              8373
     (Name)        (Area Code)   (Telephone Number)



     (2) Have all other periodic reports required under Section 13 or 15(d) of
the Securities Exchange Act of 1934 or Section 30 of the Investment Company Act
of 1940 during the preceding 12 months or for such shorter period that the
registrant was required to file such report(s) been filed? If the answer is no,
identify report(s).

                                                                [X] Yes   [ ] No



     (3) Is it anticipated that any significant change in results of operations
from the corresponding period for the last fiscal year will be reflected by the
earnings statements to be included in the subject report or portion thereof?

                                                                [ ] Yes   [X] No

     If so, attach an explanation of the anticipated change, both narratively
and quantitatively, and, if appropriate, state the reasons why a reasonable
estimate of the results cannot be made.

                Morgan Stanley Quality Municipal Investment Trust
                  (Name of Registrant as Specified in Charter)

has caused this notification to be signed on its behalf by the undersigned
thereunto duly authorized.


Date: December 29, 2006                 By: Francis J. Smith
                                            ------------------------------------
                                        Name: Francis J. Smith
                                        Title: Chief Financial Officer and
                                               Treasurer