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Stock-Based Compensation - Schedule of Stock Option Activity (Detail) - $ / shares
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Share Based Compensation Stock Options Activity [Abstract]    
Number of Shares, Outstanding, Beginning balance 12,488,551  
Number of Shares, Granted 4,746,250  
Number of Shares, Forfeited (574,773)  
Number of Shares, Cancelled (227,419)  
Number of Shares, Exercised (738,934)  
Number of Shares, Outstanding, Ending balance 15,693,675 12,488,551
Weighted Average Exercise Price, Outstanding $ 2.66  
Weighted Average Exercise Price, Granted 1.25  
Weighted Average Exercise Price, Forfeited 2.35  
Weighted Average Exercise Price, Cancelled 4.16  
Weighted Average Exercise Price, Exercised 0.59  
Weighted Average Exercise Price, Outstanding $ 2.32 $ 2.66
Weighted-Average Remaining Contractual Term (Years) 7 years 9 months 10 days 8 years 29 days