Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Operating Activities
Net loss	$ (119,980)	$ (46,948)	$ (37,652)
Adjustments to reconcile net loss to net cash and cash equivalents used in operating activities:
Depreciation	1,942	1,248	807
Amortization of intangible assets	6,967	2,185	503
Amortization of debt discount and debt issuance costs	177	142	83
Stock-based compensation	5,033	3,311	1,840
Common stock issued for services	116
Inventory write-down related to restructuring	2,565
Loss on disposal of property		34	86
Non-cash restructuring and other charges	2,556
Goodwill impairment	61,784	0
Deferred tax benefit	(5,562)	(1,024)
Change in fair value of contingent consideration	482	(400)
Changes in operating assets and liabilities, net of effect of acquisition:
Accounts receivable	(1,041)	133	55
Interest receivable	(6)	(5)	67
Inventories	(6,647)	(4,630)	701
Other current and long term assets	(1,528)	728	(170)
Accounts payable	(356)	1,096	(36)
Accrued expenses	1,112	5,371	363
Net cash and cash equivalents used in operating activities	(52,386)	(38,759)	(33,353)
Investing Activities
Payment for acquisition of a business		(25,000)
Proceeds from sale and maturities of investments			6,191
Proceeds from sale of property and equipment			25
Purchase of property and equipment	(1,361)	(1,234)	(2,174)
Net cash and cash equivalents (used in) provided by investing activities	(1,361)	(26,234)	4,042
Financing Activities
Payment of debt	(6,902)		(2,877)
Payment of contingent consideration	(1,182)
Proceeds from issuance of common stock, net of issuance costs	58,029	58,331	52,433
Proceeds from issuance of debt, net of debt discount		9,887	4,291
Taxes paid related to net share settlement of vesting of restricted stock units	(168)	(73)
Proceeds from exercise of stock options and warrants	166	259	91
Net cash and cash equivalents provided by financing activities	49,943	68,404	53,938
Effect of exchange rate changes on cash and cash equivalents	(55)	22
Net (decrease) increase in cash, cash equivalents and restricted cash	(3,859)	3,433	24,627
Cash, cash equivalents and restricted cash, beginning of period	38,449	35,016	10,389
Cash, cash equivalents and restricted cash, end of period	34,590	38,449	35,016
Supplemental Disclosure for Cash Flow Information
Interest paid	1,289	973	904
Supplemental Schedule of Noncash Investing Activities
Transfer of inventory to property and equipment	$ 3,198
Issuance of common stock warrants		97	$ 54
Contingent consideration related to acquisition		23,900
Issuance of common stock related to acquisition		$ 43,677