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Quarterly Results of Operation (Unaudited) - Summary of Unaudited Quarterly Results of Operations (Detail) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Quarterly Financial Information Disclosure [Abstract]                      
Total revenues $ 53 $ 1,466             $ 1,519   $ 401
Cost of goods sold 38 1,031             1,069    
Amortization of intangible assets 1,655 1,709 $ 1,786 $ 1,817 $ 1,596 $ 338 $ 126 $ 125 6,967 $ 2,185 503
Goodwill impairment     61,784           61,784 0  
Restructuring and other charges (21)   3,085           3,064    
Inventory write-down related to restructuring     2,565           2,565    
Acquisition related costs         228 4,003     0 4,231  
Other operating expenses 12,769 12,278 11,509 13,163 12,076 9,223 8,942 9,714 49,719 39,955  
Interest expense, net 420 462 394 578 604 436 280 281 1,854 1,601 1,043
Loss before income taxes (14,808) (14,014) (81,123) (15,558) (14,504) (14,000) (9,348) (10,120) (125,503) (47,972) (37,652)
Income tax benefit 816 1,070 992 2,645 925 99     5,523 1,024  
Net loss $ (13,992) $ (12,944) $ (80,131) $ (12,913) $ (13,579) $ (13,901) $ (9,348) $ (10,120) $ (119,980) $ (46,948) $ (37,652)
Net loss per share - basic and diluted $ (0.12) $ (0.11) $ (0.70) $ (0.12) $ (0.13) $ (0.16) $ (0.14) $ (0.16) $ (1.07) $ (0.59) $ (0.64)