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Note 13 - Stock-based Compensation - Stock Option Activity (Details) - $ / shares
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Options, Outstanding, Number of Shares (in shares) 7,584,967  
Options, Outstanding, Weighted Average Exercise Price (in dollars per share) $ 4.22  
Options, Outstanding, Weighted Average Remaining Contractual Term (Year) 4 years 9 months 18 days 5 years 3 months 21 days
Options, Granted, Number of Shares (in shares) 3,047,615  
Options, Grants in Period, Weighted Average Exercise Price (in dollars per share) $ 0.71  
Options, Forfeited, Number of Shares (in shares) (149,430)  
Options, Forfeitures in Period, Weighted Average Exercise Price (in dollars per share) $ 0.78  
Options, Cancelled, Number of Shares (in shares) (25,173)  
Options, Expirations in Period, Weighted Average Exercise Price (in dollars per share) $ 27.32  
Options, Exercised, Number of Shares (in shares) (13,300)  
Options, Exercises in Period, Weighted Average Exercise Price (in dollars per share) $ 0.38  
Options, Outstanding, Number of Shares (in shares) 10,444,679 7,584,967
Options, Outstanding, Weighted Average Exercise Price (in dollars per share) $ 3.2 $ 4.22