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Note 12 - Income Taxes (Tables)
12 Months Ended
Dec. 31, 2023
Notes Tables  
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
   

2023

   

2022

 
    (in thousands)  

Current income taxes

               

Federal

  $ -     $ -  

State

    -       -  

Foreign

    196       239  

Deferred income taxes

    -          

Federal

    -       -  

State

    -       -  

Foreign

    118       79  

Total income tax expense

  $ 314     $ 318  
Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]
   

2023

   

2022

 
    (in thousands)  

United States

  $ (53,226 )   $ (44,802 )

Foreign

    (24,893 )     (30,441 )

Total loss from operations before taxes

  $ (78,119 )   $ (75,243 )
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
   

2023

   

2022

 
    (in thousands)  

Deferred Tax assets:

               

Stock-based compensation

  $ 3,119     $ 2,840  

Accrued expenses and other

    2,666       2,538  

Research credit carryforward

    2,859       1,341  

Fixed assets

    319       162  

Capitalized start-up costs and other intangibles

    644       921  

Capitalized research costs

    9,064       4,382  

Net operating loss carryforwards

    93,332       83,908  
      112,003       96,092  

Valuation allowance

    (110,511 )     (94,704 )

Net deferred tax asset

    1,492       1,388  

Deferred tax liabilities

               

Fixed assets and other

    (1,448 )     (1,214 )

Net deferred tax liability

    (1,448 )     (1,214 )

Net deferred tax asset

  $ 44     $ 174  
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
   

2023

   

2022

 
    (in thousands)  

Beginning balance

  $ 335     $ 141  

Gross increases for tax positions related to current periods

    328       194  

Gross decreases related to 382 limitations

    52       -  

Ending balance

  $ 715     $ 335  
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
    2023     2022  
   

Amount

   

Percent of

Pretax

Earnings

   

Amount

   

Percent of

Pretax

Earnings

 
    (in thousands)  

United States federal tax at statutory rate

  $ (16,405 )     21.0 %   $ (15,801 )     21.0 %

State taxes (net of deferred benefit)

    (2,493 )     3.2 %     (2,912 )     3.9 %

Nondeductible expenses

    755       (1.0 %)     1,077       (1.4 %)

Change in fair market value of contingent consideration

    244       (0.3 %)     (283 )     0.4 %

Warrant remeasurement and financing costs

    (140 )     0.2 %     -       -  

Research & development

    (1,898 )     2.4 %     (970 )     1.3 %

Change in unrecognized tax benefits

    380       (0.5 %)     194       (0.3 %)

Foreign tax rate differential

    3,176       (4.1 %)     2,676       (3.6 %)

True-up to stock compensation - cancellations

    -       -       49       (0.1 %)

Change in enacted tax rates and other, net

    659       (0.8 %)     (96 )     0.0  

Change in valuation allowance

    16,036       (20.5 %)     16,384       (21.8 %)

Income tax expense (benefit)

  $ 314       (0.4 %)   $ 318       (0.4 %)