Note 4 - Fair Value (Tables)

3 Months Ended

Mar. 31, 2022

Notes Tables

Fair Value, Assets Measured on Recurring Basis [Table Text Block]

	March 31, 2022
	(in thousands)
Description	Quoted Prices in Active Markets for Identical Assets (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)		Total
Assets measured at fair value
Cash and cash equivalents (1)	$	24,828	$	-	$	-	$	24,828
Restricted cash		1,176		-		-		1,176
Short-term investments		-		78,913		-		78,913
Long-term investments		-		14,727		-		14,727
Total assets measured at fair value	$	26,004	$	93,640	$	-	$	119,644
Liabilities measured at fair value
Contingent consideration	$	-	$	-	$	2,217	$	2,217
Total liabilities measured at fair value	$	-	$	-	$	2,217	$	2,217

	December 31, 2021
	(in thousands)
Description	Quoted Prices in Active Markets for Identical Assets (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)		Total
Assets measured at fair value
Cash and cash equivalents (1)	$	18,129	$	-	$	-	$	18,129
Restricted cash		1,154		-		-		1,154
Short-term investments		-		80,262		-		80,262
Long-term investments		-		37,435		-		37,435
Total assets measured at fair value	$	19,283	$	117,697	$	-	$	136,980
Liabilities measured at fair value
Contingent consideration	$	-	$	-	$	2,371	$	2,371
Total liabilities measured at fair value	$	-	$	-	$	2,371	$	2,371

Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]

	Valuation Methodology	Significant Unobservable Input	March 31, 2022		December 31, 2021
Contingent consideration	Probability weighted income approach	Milestone dates		2031		2031
		Discount rate		9.5%		9.5%
		Revenue volatility		40.0%		39.0%
		EUR-to-USD exchange rate		1.11		1.14

Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]

	Fair Value Measurement at Reporting Date (Level 3)
	(in thousands)
	Series B Warrants			Contingent consideration
Balance at December 31, 2020	$	255		$	3,936
Exercise of warrants		(2,236	)		-
Change in fair value		1,981			257
Balance at March 31, 2021	$	-		$	4,193
Balance at December 31, 2021		-			2,371
Change in fair value		-			(154	)
Balance at March 31, 2022	$	-		$	2,217
Current portion	$	-		$	-
Long-term portion		-			2,217
Balance at March 31, 2022	$	-		$	2,217