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Note 11 - Income Taxes (Tables)
12 Months Ended
Dec. 31, 2020
Notes Tables  
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
  

2020

  

2019

 

Current income taxes

        

Federal

 $  $ 

State

      

Foreign

  169   100 

Deferred income taxes

        

Federal

      

State

      

Foreign

  (1,685)  (3,224)

Total income tax expense (benefit)

 $(1,516) $(3,124)
Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]
  

2020

  

2019

 

United States

 $(34,398

)

 $(91,935

)

Foreign

  (26,430

)

  (65,390

)

Total loss from operations before taxes

 $(60,828

)

 $(157,325

)

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
  

2020

  

2019

 

Deferred tax assets:

        

Stock-based compensation

 $4,253  $3,665 

Accrued expenses and other

  906   1,007 

Research credit carryforward

  7,209   6,776 

Fixed assets

  385   345 

Capitalized start-up costs and other intangibles

  2,686   3,618 

Net operating loss carryforwards

  122,193   113,410 
   137,632   128,821 

Valuation allowance

  (132,928

)

  (123,108

)

Net deferred tax asset

  4,704   5,713 

Deferred tax liabilities

        

Fixed assets and other

  (1,590

)

  (1,445

)

Purchase accounting intangibles

  (2,807

)

  (5,660

)

Net deferred tax liability

  (4,397

)

  (7,105

)

Net deferred tax asset (liability)

 $307  $(1,392

)

Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
  

2020

  

2019

 

Beginning balance

 $1,512  $1,363 

Gross increases for tax positions related to current periods

  108   149 

Gross increases for tax positions related to prior periods

      

Ending balance

 $1,620  $1,512 
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
  

2020

  

2019

 
      

Percent of Pretax

      

Percent of Pretax

 
  

Amount

  

Earnings

  

Amount

  

Earnings

 

United States federal tax at statutory rate

 $(12,774)  21.0% $(33,038)  21.0%

State taxes (net of deferred benefit)

  (1,768)  2.9%  (4,778)  3.0%

Nondeductible expenses

  719   (1.2%)  709   (0.5%)

Change in fair market value of contingent consideration

  717   (1.2%)  (2,342)  1.5%

Warrant remeasurement and financing costs

  82   (0.1%)  (551)  0.4%

Research & Development credits

  (542)  0.9%  (743)  0.5%

Change in unrecognized tax benefits

  108   (0.2%)  149   (0.1%)

Foreign tax rate differential

  1,589   (2.6%)  2,590   (1.6%)

Goodwill and investment impairments

     (0%)  (6,638)  4.2%

Change in enacted tax rates and other, net

  533   (0.9%)  (253)  0.2%

Change in valuation allowance

  9,820   (16.1%)  41,771   (26.6%)

Income tax benefit

 $(1,516)  2.5% $(3,124)  2.0%