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Income Taxes (Details) (USD $)
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Deferred tax assets/(liabilities) [Abstract]      
Net operating loss carryforwards $ 46,711,000 $ 36,111,000  
Research & development and other credits 2,329,000 1,856,000  
Patents and licenses (11,934,000) (1,066,000)  
Other, net 737,000 0  
Total 37,843,000 36,901,000  
Valuation allowance (46,121,000) (36,901,000)  
Net deferred tax (liabillities) (8,278,000) 0  
Income tax rate reconciliation [Abstract]      
Computed tax benefit at federal statutory rate (in hundredths) (34.00%) (34.00%) (34.00%)
Permanent differences (in hundredths) 15.00% 3.00% (1.00%)
Losses for which no benefit has been recognized (in hundredths) 18.00% 28.00% 41.00%
State tax benefit, net of effect on federal income taxes (in hundredths) (4.00%) 0.00% (6.00%)
Research and development and other credits (in hundredths) (1.00%) 3.00% 0.00%
Total (in hundredths) (6.00%) 0.00% 0.00%
Net operating loss carryforwards for federal tax purposes 99,100,000    
Net operating loss carryforwards for state tax purposes 70,200,000    
Tax Credit Carryforward [Line Items]      
Foreign net operating loss carryforwards 48,400,000    
Deferred income tax benefit 3,280,695 0 0
Deferred federal income tax benefit 2,800,000    
Deferred state income tax benefit 480,000    
Percentage of change in ownership (in hundredths) 50.00%    
Period in which change of ownership for a specified percentage should occur 3 years    
Federal [Member]
     
Tax Credit Carryforward [Line Items]      
Tax credit carryforwards 1,076,000    
State [Member]
     
Tax Credit Carryforward [Line Items]      
Tax credit carryforwards $ 1,253,000