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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 LlJap4sMu0HdwpKsULhUkqGEt9KnRUff57TQWF9JYQvWq1drAANACFxWYwCMOStx
 ufeTpb6QlSwuZX7a03grIQ==

<SEC-DOCUMENT>0001204459-09-001692.txt : 20090917
<SEC-HEADER>0001204459-09-001692.hdr.sgml : 20090917
<ACCEPTANCE-DATETIME>20090917181251
ACCESSION NUMBER:		0001204459-09-001692
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20090915
FILED AS OF DATE:		20090917
DATE AS OF CHANGE:		20090917

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Wegman Thomas
		CENTRAL INDEX KEY:			0001355189

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-34236
		FILM NUMBER:		091075297

	MAIL ADDRESS:	
		STREET 1:		1764 BRIAR PLACE
		CITY:			MERRICK
		STATE:			NY
		ZIP:			11566

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BIOSPECIFICS TECHNOLOGIES CORP
		CENTRAL INDEX KEY:			0000875622
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				113054851
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		35 WILBUR ST
		CITY:			LYNBROOK
		STATE:			NY
		ZIP:			11563
		BUSINESS PHONE:		5165937000

	MAIL ADDRESS:	
		STREET 1:		35 WILBUR STREET
		CITY:			LYNBROOK
		STATE:			NY
		ZIP:			11563
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>form4.xml
<DESCRIPTION>STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2009-09-15</periodOfReport>

    <issuer>
        <issuerCik>0000875622</issuerCik>
        <issuerName>BIOSPECIFICS TECHNOLOGIES CORP</issuerName>
        <issuerTradingSymbol>BSTC</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001355189</rptOwnerCik>
            <rptOwnerName>Wegman Thomas</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1764 BRIAR PLACE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>MERRICK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>11566</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, $0.001 par value</value>
            </securityTitle>
            <transactionDate>
                <value>2009-09-15</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>100000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>24.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1255179</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>Held by the Estate of Edwin H. Wegman</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock, $0.001 par value</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>63644</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock, $0.001 par value</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>7300</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>Held by spouse and son</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The Reporting Person is an executor and beneficiary of the Estate of Edwin H. Wegman (the &quot;Estate&quot;) and is therefore deemed to beneficially own shares of the Issuer's common stock that are held by The S.J. Wegman Company, a New York limited partnership (&quot;SJW&quot;), for the benefit of the Estate as well as shares that are held directly by the Estate.  On September 15, 2009, the Estate sold an aggregate total of 100,000 shares of the Issuer's common stock held by SJW in two private transactions.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Thomas L. Wegman</signatureName>
        <signatureDate>2009-09-17</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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