0001140361-16-085613.txt : 20161109 0001140361-16-085613.hdr.sgml : 20161109 20161109164001 ACCESSION NUMBER: 0001140361-16-085613 CONFORMED SUBMISSION TYPE: 10-Q PUBLIC DOCUMENT COUNT: 39 CONFORMED PERIOD OF REPORT: 20160930 FILED AS OF DATE: 20161109 DATE AS OF CHANGE: 20161109 FILER: COMPANY DATA: COMPANY CONFORMED NAME: BIOSPECIFICS TECHNOLOGIES CORP CENTRAL INDEX KEY: 0000875622 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 113054851 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 10-Q SEC ACT: 1934 Act SEC FILE NUMBER: 001-34236 FILM NUMBER: 161984784 BUSINESS ADDRESS: STREET 1: 35 WILBUR ST CITY: LYNBROOK STATE: NY ZIP: 11563 BUSINESS PHONE: 5165937000 MAIL ADDRESS: STREET 1: 35 WILBUR STREET CITY: LYNBROOK STATE: NY ZIP: 11563 10-Q 1 form10q.htm BIOSPECIFICS TECHNOLOGIES CORP 10-Q 9-30-2016

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
 Washington, D.C. 20549

FORM 10-Q

(Mark One)
☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
 EXCHANGE ACT OF 1934
 For the quarterly period ended September 30, 2016

OR

☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
 ACT OF 1934
 For the transition period from __________________to __________________

 001-34236
 (Commission file number)

BIOSPECIFICS TECHNOLOGIES CORP.
 (Exact Name of Registrant as Specified in Its Charter)
 
Delaware
 
11-3054851
(State or Other Jurisdiction
 
(I.R.S. Employer
 of Incorporation or Organization)    Identification No.)
 
35 Wilbur Street Lynbrook, NY 11563
 (Address of Principal Executive Offices) (Zip Code)

516.593.7000
 (Registrant’s Telephone Number, Including Area Code)

Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.

Yes ☒ No ☐
 
Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Date File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).

Yes ☒ No ☐
 
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer
Accelerated filer
Non-accelerated filer
☐ (Do not check if a smaller reporting company)
Smaller reporting company

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).

Yes ☐ No ☒
 
Indicate the number of shares outstanding of the issuer's classes of common stock, as of the latest practicable date:
 
Class of Stock
Outstanding November 8, 2016
Common Stock ($.001 par value)
7,147,159
 


BIOSPECIFICS TECHNOLOGIES CORP.

TABLE OF CONTENTS
 
 
Page
 
PART I – FINANCIAL INFORMATION
 
ITEM 1.
Financial Statements
 
5
 
6
 
7
ITEM 2.
17
ITEM 3.
25
ITEM 4.
25

 
PART II – OTHER INFORMATION
 
ITEM 1.
26
ITEM 1A.
26
ITEM 2.
26
ITEM 6.
26
 
27
 
Introductory Comments – Terminology

Throughout this Quarterly Report on Form 10-Q, the terms “BioSpecifics,” “Company,” “we,” “our,” and “us” refer to BioSpecifics Technologies Corp. and its subsidiary, Advance Biofactures Corp.

Throughout this Quarterly Report on Form 10-Q, Endo Global Ventures, a Bermuda unlimited liability company, an affiliate of Endo International plc, and Endo International plc are referred to collectively as “Endo”.

Introductory Comments – Forward-Looking Statements

This Report includes “forward-looking statements” within the meaning of, and made pursuant to the safe harbor provisions of, the Private Securities Litigation Reform Act of 1995. All statements other than statements of historical fact, including statements regarding our strategy, future operations, future financial position, future revenues, projected costs, prospects, plans and objectives of management, expected revenue growth, and the assumptions underlying or relating to such statements, are “forward-looking statements.” The forward-looking statements in this Report include statements concerning, among other things, the continued successful commercialization of XIAFLEX to treat Dupuytren’s contracture and Peyronie’s disease; the continued successful marketing and commercialization of XIAFLEX to treat Dupuytren’s contracture and Peyronie’s disease in Europe, Eurasia, Japan, Canada and Australia; Endo’s ability to obtain  required regulatory approvals; Endo’s ability to manufacture XIAFLEX at an acceptable cost, in a timely manner and with appropriate quality; successful development of CCH for additional indications; the ability to successfully develop, market and commercialize our drug candidates; the funding of research and development at medical institutions under agreements that are generally cancellable; the future receipt of payments from Endo, including milestone and royalty payments, in connection with the License Agreement; the recognition of the $8.25 million payment from Endo in connection with the First Amendment;  the plans for the repurchase of stock and reacquired stock; the suspension or discontinuation of the stock repurchase plan; the risk of doubtful accounts and how we provide for estimates of uncollectable accounts; the adoption of new accounting pronouncements and their impact; which accounting policies we consider to be critical to the estimates and judgments used to prepare the unaudited condensed consolidated financial statements; the effect of changes in interest rates on the Company’s results of operations, financial position and cash flow; changes in internal controls; the ability of internal controls and procedures to achieve desired control objectives; the existence of significant uncertain tax positions and provision for income taxes; the sufficiency of the Company’s available funds and cash flow from operations to meet our operational cash needs; whether the carrying amounts of the Company’s financial instruments approximate fair value due to the nature of the instruments; the changes in the Company’s exposure to market risk; the fair value of the Company’s stock option awards; whether the Company’s bank account balances will exceed insured limits; whether the Company is exposed to any significant credit risk on our cash; our milestone achievements and payments; whether we will continue to make payments to buy down our future royalty obligations; whether we will experience uneven payment flows due to the variance in financial terms in contracts with third parties to perform clinical trial activities and ongoing development of potential drugs; estimates concerning our development period; our interpretation of the definition of milestone; whether the Company will choose to cancel the lease prior to the expiration of the term; whether and when we will hear from Endo the results of their analysis regarding the CCH pipeline: the timing of Endo’s determination of clinical trial timelines for additional indications; and the nature of our accounts receivable balance. In some cases, these statements can be identified by forward-looking words such as “believe,” “expect,” “anticipate,” “estimate,” “likely,” “may,” “will,” “can,” and “could,” the negative or plural of these words, and other similar expressions. These forward-looking statements are predictions based on our current expectations and our projections about future events and various assumptions.  There can be no assurance that we will realize our expectations or that our beliefs will prove correct. There are a number of important factors that could cause BioSpecifics’ actual results to differ materially from those indicated by such forward-looking statements, including the timing of regulatory filings and action; the ability of Endo and its partners, Asahi Kasei Pharma Corporation and Swedish Orphan Biovitrum AB, to achieve their objectives for XIAFLEX in their applicable territories; the market for XIAFLEX in, and timing, initiation and outcome of clinical trials for, additional indications including frozen shoulder, cellulite, human lipoma, canine lipoma, uterine fibroids, plantar fibromatosis and lateral  hip fat all of which will determine the amount of milestone, royalty, mark-up on cost of goods sold, license and sublicense income BioSpecifics may receive; the potential of CCH to be used in additional indications; Endo modifying its objectives or allocating resources other than to XIAFLEX; and other risk factors identified in BioSpecifics’ Quarterly Reports on Form 10Q for the periods ended March 31, 2016 and June 30, 2016 and its Annual Report on Form 10-K for the year ended December 31, 2015 and its Current Reports on Form 8-K filed with the Securities and Exchange Commission. All forward-looking statements included in this Report are made as of the date hereof, are expressly qualified in their entirety by the cautionary statements included in this Report and, except as may be required by law, we assume no obligation to update these forward-looking statements.
 
PART I – FINANCIAL INFORMATION

Item 1:
Condensed Consolidated Financial Statements

BioSpecifics Technologies Corp.
Condensed Consolidated Balance Sheets

   
September 30,
2016
   
December 31,
2015
 
   
(unaudited)
   
(audited)
 
Assets
           
Current assets:
           
Cash and cash equivalents
 
$
4,747,745
   
$
5,137,875
 
Short term investments
   
45,075,570
     
28,347,542
 
Accounts receivable
   
3,846,752
     
2,547,920
 
Income tax receivable
   
-
     
916,843
 
Deferred royalty buy-down
   
1,215,620
     
1,017,981
 
Prepaid expenses and other current assets
   
554,401
     
383,810
 
Total current assets
   
55,440,088
     
38,351,971
 
                 
Long-term investments
   
1,443,099
     
3,596,541
 
Deferred royalty buy-down – long term, net
   
1,913,697
     
2,851,423
 
Deferred tax assets, net
   
3,370,836
     
622,972
 
Patent costs, net
   
268,928
     
275,206
 
                 
Total assets
 
$
62,436,648
   
$
45,698,113
 
                 
Liabilities and stockholders’ equity
               
Current liabilities:
               
Accounts payable and accrued expenses
   
991,867
     
611,009
 
Income taxes payable
   
279,333
     
-
 
Deferred revenue
   
1,223,479
     
149,378
 
Accrued liabilities of discontinued operations
   
78,138
     
78,138
 
Total current liabilities
   
2,572,817
     
838,525
 
                 
Long-term deferred revenue
   
6,642,441
     
49,379
 
                 
Stockholders’ equity:
               
Series A Preferred stock, $.50 par value, 700,000 shares authorized; none outstanding
   
-
     
-
 
Common stock, $.001 par value; 10,000,000 shares authorized; 7,545,167 and 7,290,167 shares issued, 7,149,559 and 6,918,579 shares outstanding as of September 30, 2016 and December 31, 2015, respectively
   
7,545
     
7,290
 
Additional paid-in capital
   
32,650,938
     
31,797,418
 
Retained earnings
   
27,694,041
     
19,238,610
 
Treasury stock, 395,608 and 371,588 shares at cost as of September 30, 2016 and December 31, 2015, respectively
   
(7,131,134
)
   
(6,233,109
)
Total stockholders’ equity
   
53,221,390
     
44,810,209
 
                 
Total liabilities and stockholders’ equity
 
$
62,436,648
   
$
45,698,113
 

See accompanying notes to condensed consolidated financial statements.
 
BioSpecifics Technologies Corp.
Condensed Consolidated Income Statements
(unaudited)

   
Three Months Ended
September 30,
   
Nine Months Ended
September 30,
 
   
2016
   
2015
   
2016
   
2015
 
Revenues:
                       
Royalties
 
$
6,119,815
   
$
5,277,494
   
$
18,843,273
   
$
15,574,234
 
Licensing revenues
   
762,345
     
1,012,345
     
787,034
     
1,037,034
 
Total Revenues
   
6,882,160
     
6,289,839
     
19,630,307
     
16,611,268
 
                                 
Costs and expenses:
                               
Research and development
   
312,907
     
258,837
     
1,005,884
     
755,038
 
General and administrative
   
1,843,368
     
1,709,044
     
5,909,785
     
5,307,431
 
Total Cost and Expenses
   
2,156,275
     
1,967,881
     
6,915,669
     
6,062,469
 
                                 
Operating income
   
4,725,885
     
4,321,958
     
12,714,638
     
10,548,799
 
                                 
Other income:
                               
Interest income
   
80,674
     
26,744
     
200,704
     
58,946
 
Other income
   
6,254
     
1,477
     
37,448
     
6,110
 
     
86,928
     
28,221
     
238,152
     
65,056
 
                                 
Income before income tax expense
   
4,812,813
     
4,350,179
     
12,952,790
     
10,613,855
 
Provision for income tax expense
   
(1,759,220
)
   
(1,479,200
)
   
(4,497,359
)
   
(3,654,772
)
                                 
Net income
 
$
3,053,593
   
$
2,870,979
   
$
8,455,431
   
$
6,959,083
 
                                 
                                 
Basic net income per share
 
$
0.43
   
$
0.42
   
$
1.20
   
$
1.02
 
Diluted net income per share
 
$
0.42
   
$
0.39
   
$
1.16
   
$
0.96
 
                                 
Shares used in computation of basic net income per share
   
7,062,543
     
6,892,637
     
7,031,068
     
6,797,506
 
Shares used in computation of diluted net income per share
   
7,280,375
     
7,316,287
     
7,277,780
     
7,259,338
 

See accompanying notes to condensed consolidated financial statements.
 
BioSpecifics Technologies Corp.
Condensed Consolidated Statements of Cash Flows
(unaudited)

   
Nine Months Ended
September 30,
 
Cash flows from operating activities:
 
2016
   
2015
 
Net income
 
$
8,455,431
   
$
6,959,083
 
Adjustments to reconcile net income to net cash provided by operating activities:
               
Amortization
   
1,215,814
     
647,071
 
Stock-based compensation expense
   
100,428
     
72,305
 
Deferred tax expense
   
(2,747,864
)
   
441,211
 
Changes in operating assets and liabilities:
               
Accounts receivable
   
(1,298,832
)
   
(1,273,079
)
Income tax receivable
   
916,843
     
(521,121
)
Prepaid expenses and other current assets
   
(170,591
)
   
(136,152
)
Patent costs
   
(23,341
)
   
(24,204
)
Accounts payable and accrued expenses
   
380,858
     
107,372
 
Income taxes payable
   
279,333
     
-
 
Deferred revenue
   
7,667,163
     
(37,034
)
Net cash provided by operating activities
   
14,775,242
     
6,235,452
 
                 
Cash flows from investing activities:
               
Maturity of marketable investments
   
32,548,040
     
11,043,544
 
Purchases of marketable investments
   
(47,568,734
)
   
(24,422,334
)
Net cash used in investing activities
   
(15,020,694
)
   
(13,378,790
)
                 
Cash flows from financing activities:
               
Proceeds from stock option exercises
   
529,300
     
2,813,984
 
Payments for repurchase of common stock
   
(898,025
)
   
(1,182,068
)
Excess tax benefits from share-based payment arrangements
   
224,047
     
3,188,682
 
Net cash (used in) provided by financing activities
   
(144,678
)
   
4,820,598
 
                 
Decrease in cash and cash equivalents
   
(390,130
)
   
(2,322,740
)
Cash and cash equivalents at beginning of year
   
5,137,875
     
9,810,816
 
Cash and cash equivalents at end of period
 
$
4,747,745
   
$
7,488,076
 
                 
Supplemental disclosures of cash flow information:
               
Cash paid during the period for:
               
Interest
   
-
     
-
 
Taxes
 
$
5,825,000
   
$
546,000
 

See accompanying notes to condensed consolidated financial statements.
 
BIOSPECIFICS TECHNOLOGIES CORP.
 NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

September 30, 2016
(Unaudited)

1.
ORGANIZATION AND DESCRIPTION OF BUSINESS

We are a biopharmaceutical company involved in the development of an injectable collagenase clostridium histolyticum, or CCH, for multiple indications. We currently have a development and license agreement with Endo Global Ventures International plc (together with Endo International plc, an affiliate of Endo Global Ventures, “Endo”) for injectable collagenase for marketed indications and indications in development. Endo assumed this agreement when Endo acquired Auxilium Pharmaceuticals, Inc. (“Auxilium”) on January 29, 2015 (the “Acquisition”).  CCH is marketed as XIAFLEX® (or XIAPEX® in Europe).

On February 5, 2016, we announced that we had entered into with Endo the First Amendment (the “First Amendment”) to the Second Amended and Restated Development and Licensing Agreement (the “Auxilium Agreement”), by and between us and Auxilium, now a wholly-owned subsidiary of Endo, to amend certain provisions of the Auxilium Agreement (as amended by the First Amendment, the “License Agreement”). The effective date of the First Amendment was January 1, 2016. Pursuant to the First Amendment, we and Endo mutually agreed that in exchange for a $8.25 million lump sum payment, we will not receive future additional mark-up on cost of goods sold for sales by non-affiliated sublicensees of Endo outside of the U.S.; provided, however, that Endo will still be required to pay a mark-up on cost of goods sold for sales made in the "Endo Territory," which includes sales made in the U.S. and sales made in any other country where Endo sells the product directly or through affiliated sublicensees. We received this $8.25 million lump sum payment in February 2016 and began recognizing this income over time based on sales by non-affiliated sublicensees of Endo outside of the U.S. according to our revenue recognition policy in the second quarter of 2016.

Additionally, we agreed that Endo may opt-in early to indications, prior to our submission of a clinical trial report, with our consent, such consent not to be unreasonably withheld. For early opt-ins, Endo will be required to make an opt-in payment of $0.5 million on a per indication basis. For regular opt-ins, following our submission of a clinical trial report, Endo will be required to make an opt-in payment of $0.75 million on a per indication basis.

The two marketed indications involving our injectable collagenase are Dupuytren’s contracture and Peyronie’s disease. Prior to the Acquisition, Auxilium had, and after the Acquisition, Endo has, opted-in to the following indications: frozen shoulder, cellulite, canine lipoma, lateral hip fat, plantar fibromatosis and human lipoma. We manage the development of CCH for uterine fibroids and initiate the development of CCH in new potential indications, not licensed by Endo.

Endo is currently selling XIAFLEX in the U.S. for the treatment of Dupuytren’s contracture and Peyronie’s disease and has an agreement with Swedish Orphan Biovitrum AB (“Sobi”), pursuant to which Sobi has marketing rights for XIAPEX for Dupuytren’s contracture and Peyronie’s disease in Europe and certain Eurasian countries. Sobi is currently selling XIAPEX in Europe for the treatment of Dupuytren’s contracture and Peyronie’s disease. In addition, Endo has an agreement with Asahi Kasei Pharma Corporation (“Asahi”) pursuant to which Asahi has the right to commercialize XIAFLEX for the treatment of Dupuytren’s contracture and Peyronie’s disease in Japan. Asahi has received regulatory approval and is currently selling XIAFLEX for the treatment of Dupuytren’s contracture in Japan.

2.
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

Basis of Presentation

The accompanying condensed consolidated financial statements are unaudited, but include all adjustments (consisting only of normal, recurring adjustments) which we consider necessary for a fair presentation of our financial position at such dates and the operating results and cash flows for those periods. Although we believe that the disclosures in our financial statements are adequate to make the information presented not misleading, certain information normally included in financial statements prepared in accordance with U.S. generally accepted accounting principles (“U.S. GAAP”) has been condensed or omitted pursuant to the rules and regulations of the Securities and Exchange Commission (the “SEC”) for quarterly reporting.
 
The information included in this Report should be read in conjunction with the risk factors discussed in “Part I, Item 1A. Risk Factors” in our Quarterly Reports on Form 10Q for the periods ended March 31, 2016 and June 30, 2016 filed with the SEC on May 10, 2016 and August 9, 2016, respectively and our Annual Report on Form 10-K for the period ended December 31, 2015 filed with the SEC on March 14, 2016.

Principles of Consolidation

The condensed consolidated financial statements include the accounts of the Company and its subsidiary, Advance Biofactures Corp. (“ABC-NY”). All intercompany balances and transactions have been eliminated.

Critical Accounting Policies, Estimates and Assumptions

The preparation of condensed consolidated financial statements in conformity with U.S. GAAP requires the use of management’s estimates and assumptions that affect the amounts reported in the condensed consolidated financial statements and accompanying notes. The Company makes certain assumptions and estimates for its deferred tax assets and deferred royalty buy-down. For further details see notes “Provision for Income Taxes” and “Third-Party Royalties and Royalty Buy-Down.” Actual results may differ from those estimates.

Cash, Cash Equivalents and Investments

Cash equivalents include only securities having a maturity of three months or less at the time of purchase. Investments are stated on an amortized cost basis. The Company limits its credit risk associated with cash, cash equivalents and investments by placing its investments with banks it believes are highly creditworthy and with highly rated money market funds, certificates of deposit and municipal bonds. All investments are classified as held to maturity. As of September 30, 2016 and December 31, 2015, the aggregate fair value of these investments was $46.5 million and $31.9 million, respectively.

Fair Value Measurements

Management believes that the carrying amounts of the Company’s financial instruments, including cash, cash equivalents, held to maturity investments, accounts receivable, accounts payable and accrued expenses approximate fair value due to the short-term nature of those instruments. As of September 30, 2016 and December 31, 2015, there were no recorded unrealized gains or losses on our investments as they are held to maturity. As of September 30, 2016, amortized cost basis of the investments approximate their fair value. At September 30, 2016 and December 31, 2015, the amortized premium included in interest income was $446,000 and $316,000, respectively.

The following table presents the Company’s schedule of maturities at September 30, 2016 and December 31, 2015:

   
Maturities as of
September 30, 2016
   
Maturities as of
December 31, 2015
 
             
   
1 Year or Less
   
Greater than
1 Year
   
1 Year or
Less
   
Greater than 1
Year
 
                                 
Municipal bonds
 
$
6,917,696
   
$
-
   
$
6,461,216
   
$
155,826
 
                                 
Corporate Bonds
   
31,218,996
     
1,194,049
     
9,882,285
     
1,597,715
 
                                 
Certificates of deposit
   
6,938,878
     
249,050
     
12,004,041
     
1,843,000
 
Total
 
$
45,075,570
   
$
1,443,099
   
$
28,347,542
   
$
3,596,541
 
 
The authoritative literature for fair value measurements established a three-tier fair value hierarchy, which prioritizes the inputs in measuring fair value. These tiers are as follows: Level 1, defined as observable inputs such as quoted market prices in active markets; Level 2, defined as inputs other than the quoted prices in active markets that are either directly or indirectly observable; and Level 3, defined as significant unobservable inputs (entity developed assumptions) in which little or no market data exists.

As of September 30, 2016, the Company held certain investments that are required to be measured at fair value on a recurring basis. The following tables present the Company’s fair value hierarchy for these financial assets as of September 30, 2016 and December 31, 2015:

September 30, 2016
Type of Instrument
 
Fair Value
   
Level 1
   
Level 2
   
Level 3
 
                                   
Cash equivalents
Institutional Money Market
 
$
1,894,904
   
$
1,894,904
     
-
     
-
 
                                   
Investments
Municipal Bonds
   
6,917,696
     
-
   
$
6,917,696
     
-
 
                                   
Investments
Corporate Bonds
   
32,413,045
     
-
     
32,413,045
     
-
 
                                   
Investments
Certificates of Deposit
   
7,187,928
     
7,187,928
     
-
     
-
 
                           
December 31, 2015
Type of Instrument
 
Fair Value
   
Level 1
   
Level 2
   
Level 3
 
                                   
Cash equivalents
Institutional Money Market
 
$
715,784
   
$
715,784
     
-
     
-
 
                                   
Investments
Municipal Bonds
   
6,617,042
     
-
   
$
6,617,042
     
-
 
                                   
Investments
Corporate Bonds
   
11,480,000
     
-
     
11,480,000
     
-
 
                                   
Investments
Certificates of Deposit
   
13,847,041
     
13,847,041
     
-
     
-
 
 
Concentration of Credit Risk and Major Customers

The Company maintains bank account balances, which, at times, may exceed insured limits. The Company has not experienced any losses with these accounts and believes that it is not exposed to any significant credit risk on cash.

The Company maintains its investment in FDIC insured certificates of deposits with several banks, pre-refunded municipal bonds, municipal bonds and corporate bonds.

The Company is currently dependent on one customer, Endo, who generates almost all its revenues. For the three and nine months ended September 30, 2016, licensing, sublicensing, milestones and royalty revenues under the License Agreement with Endo were approximately $6.9 million and $19.6 million, respectively, and for the three and nine months ended September 30, 2015, the licensing, sublicensing, milestones and royalty revenues under the License Agreement with Endo were approximately $6.3 million and $16.6 million, respectively.

At September 30, 2016 and December 31, 2015, our accounts receivable balances were $3.8 million and $2.5 million, respectively.

Revenue Recognition
 
We currently recognize revenues resulting from the licensing and sublicensing of the use of our technology and from services we sometimes perform in connection with the licensed technology under the guidance of Accounting Standards Codification 605, Revenue Recognition (“ASC 605”).

If we determine that separate elements exist in a revenue arrangement under ASC 605, we recognize revenue for delivered elements only when the fair values of undelivered elements are known, when the associated earnings process is complete, when payment is reasonably assured and, to the extent the milestone amount relates to our performance obligation, when our customer confirms that we have met the requirements under the terms of the agreement.
 
Revenues, and their respective treatment for financial reporting purposes, are as follows:
 
Royalty / Mark-Up on Cost of Goods Sold

For those arrangements for which royalty and mark-up on cost of goods sold information becomes available and collectability is reasonably assured, we recognize revenue during the applicable period in which it is earned. For interim quarterly and year-end reporting purposes, when collectability is reasonably assured, but a reasonable estimate of royalty and mark-up on cost of goods sold cannot be made, the royalty and mark-up on cost of goods sold are generally recognized in the quarter that the applicable licensee provides the written report and related information to us.

Under the License Agreement, we do not participate in the selling, marketing or manufacturing of products for which we receive royalties and a mark-up on the cost of goods sold. The royalty and mark-up on cost of goods sold will generally be recognized in the quarter that Endo provides the written reports and related information to us; that is, royalty and mark-up on cost of goods sold are generally recognized one quarter following the quarter in which the underlying sales by Endo occurred. The royalties payable by Endo to us are subject to set-off for certain patent costs.

Pursuant to the First Amendment with Endo, in exchange for a $8.25 million lump sum payment, we will not receive future additional mark-up on cost of goods sold for sales by non-affiliated sublicensees of Endo outside of the U.S.; provided, however, that Endo will still be required to pay a mark-up on cost of goods sold for sales made in the “Endo Territory,” which includes sales made in the U.S. and sales made in any other country where Endo sells the product directly or through affiliated sublicensees. We received this $8.25 million lump sum payment in February 2016. We classified this payment as deferred revenue in our balance sheet and began recognizing this income over time in the second quarter of 2016 based on sales by non-affiliated sublicensees of Endo outside of the U.S. according to our revenue recognition policy. We recognized approximately $274,000 and $546,000 for the three and nine months ended September 30, 2016, and zero in each of the 2015 corresponding periods.

Licensing Revenue

We include revenue recognized from upfront licensing, sublicensing and milestone payments in “License Revenues” in our condensed consolidated statements of income in this Quarterly Report on Form 10-Q.

Upfront License and Sublicensing Fees

We generally recognize revenue from upfront licensing and sublicensing fees when the license or sublicense agreement is signed, we have completed the earnings process and we have no ongoing performance obligation with respect to the arrangement. We recognized licensing fees related to the exercise of an opt-in right by Endo for the human lipoma indication of $750,000 for the three and nine months ended September 30, 2016 as compared to zero in each of the 2015 periods. Nonrefundable upfront technology license fees for product candidates for which we are providing continuing services related to product development are deferred and recognized as revenue over the development period. We recognized deferred revenue of $12,345 and $37,034 for the three and nine months ended September 30, 2016, respectively, and $12,345 and $37,034 for the three and nine months ended September 30, 2015, respectively.

Milestones

Milestones, in the form of additional license fees, typically represent nonrefundable payments to be received in conjunction with the achievement of a specific event identified in the license or sublicense agreement, such as completion of specified development activities and/or regulatory submissions and/or approvals. We believe that a milestone represents the culmination of a distinct earnings process when it is not associated with ongoing research, development or other performance on our part. We recognize such milestones as revenue when they become due and collection is reasonably assured. When a milestone does not represent the culmination of a distinct earnings process, we recognize revenue in a manner similar to that of an upfront license fee.
 
The timing and amount of revenue that we recognize from licenses of technology, either from upfront fees or milestones where we are providing continuing services related to product development, are primarily dependent upon our estimates of the development period. We define the development period as the point from which research activities commence up to regulatory approval of either our or our partners’ submission, assuming no further research is necessary. As product candidates move through the development process, it is necessary to revise these estimates to consider changes to the product development cycle, such as changes in the clinical development plan, regulatory requirements, or various other factors, many of which may be outside of our control. Should the U.S. Food and Drug Administration (“FDA”) or other regulatory agencies require additional data or information, we would adjust our development period estimates accordingly. The impact on revenue of changes in our estimates and the timing thereof is recognized prospectively over the remaining estimated product development period. We did not recognize any milestone revenue in the three and nine month periods ended September 30, 2016. Milestone revenue recognized for the three and nine months ended September 30, 2015 was $1.0 million in each period.  The $1.0 million milestone revenue recognized in the 2015 periods related to the first commercial sale of XIAFLEX by Asahi for the treatment of Dupuytren's contracture in Japan.

Treasury Stock
 
The Company accounts for treasury stock under the cost method and includes treasury stock as a component of stockholders’ equity. For the nine months ended September 30, 2016, we repurchased 24,020 shares at an average price of $37.39 as compared to the repurchase of 27,433 shares at an average price of $43.07 in the corresponding 2015 period.
 
Receivables and Doubtful Accounts
 
Trade accounts receivable are stated at the amount the Company expects to collect. We may maintain allowances for doubtful accounts for estimated losses resulting from the inability of our customers to make required payments. We consider the following factors when determining the collectability of specific customer accounts: customer credit-worthiness, past transaction history with the customer, current economic industry trends, and changes in customer payment terms.  Our accounts receivable balance is typically due from Endo, our one large specialty pharmaceutical customer.  Endo has historically paid timely and has been a financially stable organization.  Due to the nature of the accounts receivable balance, we believe the risk of doubtful accounts is minimal.  If the financial condition of our customer were to deteriorate, adversely affecting its ability to make payments, additional allowances would be required.  We may provide for estimated uncollectible amounts through a charge to earnings and a credit to a valuation allowance. Balances that remain outstanding after we have used reasonable collection efforts are written off through a charge to the valuation allowance and a credit to accounts receivable. At September 30, 2016 and December 31, 2015 our accounts receivable balance was $3.8 million and $2.5 million, respectively, and was from one customer, Endo.

Deferred Revenue

Deferred revenue consists of the remaining $7.7 million related to the First Amendment with Endo of mark-up on cost of goods sold revenue for sales by non-affiliated sublicensees, approximately $62,000 related to nonrefundable upfront product license fees for product candidates for which we are providing continuing services related to product development and $100,000 related to a milestone payment withheld by Endo due to a foreign tax withholding which remains uncollected. Currently, the Company expects to recover the full amount. As of September 30, 2016 and December 31, 2015, deferred revenue was $7.9 million and $0.2 million, respectively.

Reimbursable Third-Party Development Costs

We accrued patent expenses for that are reimbursable by us under the License Agreement.  We capitalize certain patent costs related to estimated third-party development costs that are reimbursable under the License Agreement. As of September 30, 2016 and December 31, 2015, our net reimbursable third party patent expense accrual was approximately $25,000 and $20,000, respectively.

Third-Party Royalties

We have entered into licensing and royalty agreements with third parties and agreed to pay certain royalties on net sales of products for specific indications. The royalty rates differ from agreement to agreement and, in certain cases, have been redacted with the permission of the SEC.  No assumptions should be made that any disclosed royalty rate payable to a particular third party is the same or similar with respect to any royalty rate payable to any other third parties.  We accrue third-party royalty expenses on net sales reported to us by Endo. Third-party royalty costs are generally expensed in the quarter that Endo provides the written reports and related information to us; that is, generally one quarter following the quarter in which the underlying sales by Endo occurred. For the three and nine month periods ended September 30, 2016, third-party royalty expenses were $0.4 million and $1.2 million , respectively, and for the three and nine month periods ended September 30, 2015, third-party royalty expenses were $0.3 million and $1.0 million, respectively. Our third-party royalty expense under general and administrative expenses may increase if net sales by Endo and its partners for XIAFLEX and XIAPEX increase and potential new indications for CCH are approved.
 
Royalty Buy-Down

On March 31, 2012, we entered into an amendment to our existing agreement with Dr. Martin K. Gelbard, dated August 27, 2008, related to our future royalty obligations in connection with Peyronie’s disease. The amendment enables us to buy down a portion of our future royalty obligations in exchange for an initial cash payment of $1.5 million and five additional cash payments of $600,000, three of which have been paid as of September 30, 2016.  We are currently making the payments to buy down the future royalty obligations, which royalty obligations terminate five years after first commercial sale. The Company amortizes long-term contracts with finite lives in a manner that reflects the pattern in which the economic benefits of the assets are consumed or otherwise used up. Dr. Gelbard’s agreement is amortized based on an income forecast method by estimating sales of XIAFLEX for Peyronie’s disease on an annual basis as measured by the proportion of the total estimated sales over the five year period. Related to this agreement, we amortized approximately $247,000 and $740,000 for the three and nine months ended September 30, 2016, respectively, and $221,000 and $420,000 for the three and nine months ended September 30, 2015, respectively. The remaining capitalized balance as of September 30, 2016 was $3.1 million. We perform an evaluation of the recoverability of the carrying value to determine if facts and circumstances indicate that the carrying value of the assets may be impaired and if any adjustment is warranted. Based on our evaluation as of September 30, 2016, no impairment existed and no adjustment was warranted.
 
R&D Expenses

R&D expenses include, but are not limited to, internal costs, such as salaries and benefits, costs of materials, lab expenses, facility costs and overhead. R&D expenses also consist of third party costs, such as medical professional fees, product costs used in clinical trials, consulting fees and costs associated with clinical study arrangements. We may fund R&D at medical research institutions under agreements that are generally cancelable. All of these costs are charged to R&D as incurred, which may be measured by percentage of completion, contract milestones, patient enrollment, or the passage of time.

Clinical Trial Expenses

Our cost accruals for clinical trials are based on estimates of the services received and efforts expended pursuant to contracts with various clinical trial centers and clinical research organizations. In the normal course of business we contract with third parties to perform various clinical trial activities in the ongoing development of potential drugs. The financial terms of these agreements are subject to negotiation and vary from contract to contract and may result in uneven payment flows. Payments under the contracts depend on factors such as the achievement of certain events, the successful enrollment of patients, the completion of portions of the clinical trial, and other similar conditions. The objective of our accrual policy is to match the recording of expenses in our financial statements to the actual cost of services received and efforts expended. As such, expenses related to each patient enrolled in a clinical trial are recognized ratably beginning upon entry into the trial and over the course of the patient’s continued participation in the trial. In the event of early termination of a clinical trial, we accrue an amount based on our estimate of the remaining non-cancelable obligations associated with the winding down of the clinical trial. Our estimates and assumptions could differ significantly from the amounts that may actually be incurred.

Stock-Based Compensation

The Company has one stock-based compensation plan in effect. Accounting Standards Codification 718, Compensation - Stock Compensation (“ASC 718”), requires the recognition of compensation expense, using a fair-value based method, for costs related to all stock options including stock options and common stock issued to our employees and directors under our stock plans. ASC 718 requires companies to estimate the fair value of stock option awards on the date of grant using an option-pricing model. The value of the portion of the award that is ultimately expected to vest is recognized as expense on a straight-line basis over the requisite service periods in our condensed consolidated statements of operations.
 
Under ASC 718, we estimate the fair value of our employee stock option awards at the date of grant using the Black-Scholes option-pricing model, which requires the use of certain subjective assumptions. The most significant of these assumptions are our estimates of the expected volatility of the market price of our stock and the expected term of an award. When establishing an estimate of the expected term of an option award, we consider the vesting period for the award, our recent historical experience of employee stock option exercises (including forfeitures) and the expected volatility of our common stock.  As required under the accounting rules, we review our estimates at each grant date and, as a result, the valuation assumptions that we use to value employee stock-based awards granted in future periods may change. No stock options were granted during the nine months ended September 30, 2016 and 2015.

Further, ASC 718 requires that employee stock-based compensation costs be recognized over the requisite service period, or the vesting period, in a manner similar to all other forms of compensation paid to employees. The allocation of employee stock-based compensation costs to each operating expense line are estimated based on specific employee headcount information at each grant date and estimated stock option forfeiture rates and revised, if necessary, in future periods if actual employee headcount information or forfeitures differ materially from those estimates. As a result, the amount of employee stock-based compensation costs we recognize in each operating expense category in future periods may differ significantly from what we have recorded in the current period.

Stock-based compensation expense recognized in general and administrative expenses was approximately $33,000 and $100,000 for the three and nine months ended September 30, 2016, respectively, and $33,000 and $72,000 for the three and nine months ended September 30, 2015, respectively.

Stock Option Activity

A summary of our stock option activity during the nine months ended September 30, 2016 is presented below:

   
Shares
   
Weighted
Average
Exercise
Price
   
Weighted
Average
Remaining
Contractual
Term
   
Aggregate
Intrinsic
Value
 
Outstanding at January 1, 2016
   
562,000
   
$
11.91
     
2.51
   
$
17,456,220
 
Grants
   
-
     
-
     
-
     
-
 
Exercised
   
(255,000
)
   
2.08
     
-
     
-
 
Forfeitures or expirations
   
-
     
-
     
-
     
-
 
Outstanding at September 30, 2016
   
307,000
   
$
20.08
     
3.33
   
$
7,857,070
 
Exercisable at September 30, 2016
   
260,750
   
$
17.89
     
2.83
   
$
7,243,095
 
 
During the nine months ended September 30, 2016 and 2015, the Company received $0.5 million and $2.8 million, respectively, from stock options exercised by option holders.

Aggregate intrinsic value represents the total pre-tax intrinsic value based on the closing price of our common stock of $45.67 on September 30, 2016, which would have been received by the option holders had all option holders exercised their options as of that date. We have approximately $301,000 in unrecognized compensation cost related to stock options outstanding as of September 30, 2016, which we expect to recognize over the next 2.40 years.

Property and Equipment

Property and equipment are stated at cost, less accumulated depreciation. Machinery and equipment, furniture and fixtures, and autos are depreciated on a straight-line basis over their estimated useful lives of five to ten years. Leasehold improvements are amortized over the lesser of their estimated useful lives or the remaining life of the lease. As of September 30, 2016 and December 31, 2015, respectively, property and equipment were fully depreciated.

Comprehensive Income

For the three and nine months ended September 30, 2016 and 2015, respectively, we had no components of other comprehensive income other than net income itself.
 
Provision for Income Taxes

Deferred tax assets and liabilities are recognized based on the expected future tax consequences, using current tax rates, of temporary differences between the financial statement carrying amounts and the income tax basis of assets and liabilities. A valuation allowance is applied against any net deferred tax asset if, based on the weighted available evidence, it is more likely than not that some or all of the deferred tax assets will not be realized.

We use the asset and liability method of accounting for income taxes, as set forth in Accounting Standards Codification. Under this method, deferred income taxes, when required, are provided on the basis of the difference between the financial reporting and income tax basis of assets and liabilities at the statutory rates enacted for future periods. We classify interest associated with income taxes under interest expense and tax penalties under other expense.

The Company recognizes a tax benefit from an uncertain tax position only if it is more likely than not that the tax position will be sustained on examination by taxing authorities, based on the technical merits of the position. The tax benefit recognized in the consolidated financial statements from such position is measured based on the largest benefit that has a greater than 50% likelihood of being realized upon the ultimate settlement. As of September 30, 2016 and 2015, respectively, the Company has not recorded any unrecognized tax benefits.

Commitments and Contingencies

On November 1, 2016, the Company entered into an agreement with the Landlord to extend the term of the lease to the Headquarters for an additional one year period (the “Extended Lease Agreement”). The one year extension will end on November 30, 2017. Pursuant to the Extended Lease Agreement, the base rent is $10,757 per month and the Company may cancel the lease with three months’ prior written notice to the Landlord at any time during the term. The Extended Lease Agreement was filed with the SEC as Exhibit 10.1 to the Company’s Quarterly Report on Form 10Q on November 9, 2016.

New Accounting Pronouncements

The Financial Accounting Standards Board, or FASB, issued in May 2014, in August 2015, March 2016 and April 2016, respectively, Accounting Standards Updates No. 2014-09, No. 2015-14, No. 2016-08, and No. 2016-10 (the “ASUs”). These ASUs were issued in connection with revenue from contracts with customers. The new standard provides a five-step approach to be applied to all contracts with customers and also requires expanded disclosures about revenue recognition. In August 2015, the FASB deferred the effective date of the guidance to reporting periods, including interim periods, beginning after December 15, 2017, and will be applied retrospectively. Early adoption is not permitted. We are currently evaluating the timing, method of adoption and the expected impact that the standard could have on our consolidated financial statements and related disclosures. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.
                                                                          
In January 2016, the FASB issued new guidance on recognition and measurement of financial assets and financial liabilities. The new guidance will impact the accounting for equity investments, financial liabilities under the fair value option, and the presentation and disclosure requirements for financial instruments. All equity investments in unconsolidated entities (other than those accounted for under the equity method of accounting) will generally be measured at fair value with changes in fair value recognized through earnings. There will no longer be an available-for-sale classification (changes in fair value reported in other comprehensive income (loss) for equity securities with readily determinable fair values. In addition, the FASB clarified the need for a valuation allowance on deferred tax assets resulting from unrealized losses on available-for-sale debt securities. In general, the new guidance will require modified retrospective application to all outstanding instruments, with a cumulative effect adjustment recorded to opening retained earnings. This guidance will be effective for us on January 1, 2018. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.

In February 2016, FASB issued Accounting Standards Update (ASU) No. 2016-02, Leases (Topic 842). Under the new guidance, lessees will be required to recognize the following for all leases (with the exception of short-term leases) at the lease commencement date: a lease liability, which is a lessee’s obligation to make lease payments arising from a lease, measured on a discounted basis; and a right-of-use asset, which is an asset that represents the lessee’s right to use, or control the use of, a specified asset for the lease term. Under the new guidance, lessor accounting is largely unchanged. Certain targeted improvements were made to align, where necessary, lessor accounting with the lessee accounting model and Topic 606, Revenue from Contracts with Customers. The new lease guidance simplified the accounting for sale and leaseback transactions primarily because lessees must recognize lease assets and lease liabilities. Lessees will no longer be provided with a source of off-balance sheet financing. Public business entities should apply the amendments in ASU 2016-02 for fiscal years beginning after December 15, 2018, including interim periods within those fiscal years (i.e., January 1, 2019, for a calendar year entity). Early application is permitted.  Lessees (for capital and operating leases) and lessors (for sales-type, direct financing, and operating leases) must apply a modified retrospective transition approach for leases existing at, or entered into after, the beginning of the earliest comparative period presented in the financial statements. The modified retrospective approach would not require any transition accounting for leases that expired before the earliest comparative period presented. Lessees and lessors may not apply a full retrospective transition approach. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.
 
In March 2016, FASB issued ASU No. 2016-09 related to stock-based compensation. The new guidance simplifies the accounting for stock-based compensation transactions, including income tax consequences, classification of awards as either equity or liabilities, and classification on the statement of cash flows. This update is effective in fiscal years, including interim periods, beginning after December 15, 2016, and early adoption is permitted. We are currently evaluating this guidance and the impact it will have on the consolidated financial statements and related disclosures.

In May 2016, FASB issued ASU No. 2016-12, Revenue from Contracts with Customers (Topic 606): Narrow-Scope Improvements and Practical Expedients, which is intended to not change the core principle of the guidance in Topic 606, but rather affect only the narrow aspects of Topic 606 by reducing the potential for diversity in practice at initial application and by reducing the cost and complexity of applying Topic 606 both at transition and on an ongoing basis. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.

In June 2016, FASB issued ASU 2016-13, Financial Instruments - Credit Losses. The amendment revises the impairment model to utilize an expected loss methodology in place of the currently used incurred loss methodology, which will result in more timely recognition of losses on financial instruments, including, but not limited to, available for sale debt securities and accounts receivable. The Company is required to adopt this standard starting in the first quarter of fiscal year 2021. Early adoption is permitted. We are currently evaluating the impact of the adoption of this standard on our consolidated financial statements and related disclosures.

3.
NET INCOME PER SHARE

In accordance with Accounting Standards Codification 260, Earnings Per Share, basic net income per share amount is computed using the weighted-average number of shares of common stock outstanding during the periods presented, while diluted net income per share is computed using the sum of the weighted-average number of common and common equivalent shares outstanding. Common equivalent shares used in the computation of diluted earnings per share result from the assumed exercise of stock options using the treasury stock method.

The following table summarizes the number of common equivalent shares that were excluded for the calculation of diluted net income per share reported in the condensed consolidated statement of operations.

 
 
Three Months Ended
September 30,
   
Nine Months Ended
September 30,
 
 
 
2016
   
2015
   
2016
   
2015
 
Stock options
 
20,000
   
20,000
   
20,000
   
20,000
 
 
At September 30, 2016, the Company had 20,000 options, which have an exercise price of $29.21, and will vest upon the achievement of certain performance criteria, which have not yet been met.  These options expire on December 2, 2019.

4.
ACCOUNTS PAYABLE AND ACCRUED EXPENSES

Accounts payable and accrued expenses consisted of the following:

   
September 30,
2016
   
December 31,
2015
 
Trade accounts payable and accrued expenses
 
$
728,425
   
$
372,367
 
Accrued legal and other professional fees
   
66,775
     
74,138
 
Accrued payroll and related costs
   
196,667
     
164,504
 
Total
 
$
991,867
   
$
611,009
 
 
5.
PATENT COSTS

We amortize intangible assets with definite lives on a straight-line basis over their remaining estimated useful lives, ranging from one to twelve years, and review for impairment on a quarterly basis and when events or changes in circumstances indicate that the carrying amount of such assets may not be recoverable.  We analyze our intangible assets, specifically, capitalized patent costs, on an annual basis for any indicator that an impairment exist.

We capitalized legal patent costs related to patent prosecution and maintenance. For the nine months ended September 30, 2016, we increased our capitalized patent costs by approximately $23,300, based on reports provided to us by Endo. These patent costs are creditable against future royalty revenues. For each period presented below, net patent costs consisted of:

   
September 30,
2016
   
December 31,
2015
 
Patents
 
$
720,600
   
$
697,260
 
Accumulated amortization
   
(451,672
)
   
(422,054
)
   
$
268,928
   
$
275,206
 
 

 
The amortization expense for patents for the three and nine months ended September 30, 2016 was approximately $10,300 and $29,600, respectively, and the amortization expense for patents for the three and nine months ended September 30, 2015 was approximately $11,000 and $34,000, respectively. The estimated aggregate amortization expense for the remaining three months of 2016 and each of the years below is approximately as follows:

October 1, 2016 to December 31, 2016
 
$
10,600
 
2017
   
38,700
 
2018
   
38,700
 
2019
   
38,700
 
2020
   
27,400
 
Thereafter
 
$
114,800
 
 
6.
PROVISION FOR INCOME TAXES
 
In determining our provision for income taxes, we consider all available information, including operating results, ongoing tax planning, and forecasts of future taxable income. The significant components of the Company’s deferred tax assets consist of stock-based compensation and deferred revenues. For the three and nine months ended September 30, 2016, the provision for income taxes was $1.8 million and $4.5 million, respectively. As of September 30, 2016 and December 31, 2015, our remaining deferred tax assets were approximately $3.4 million and $0.6 million, respectively.
 
For the three and nine month periods ended September 30, 2015, the provision for income taxes was $1.5 million and $3.7 million, respectively.
 
As of September 30, 2016, the Company believes that there are no significant uncertain tax positions and no amounts have been recorded for interest and penalties.
 
7.
SUBSEQUENT EVENTS
 
On November 1, 2016, the Company entered into an agreement with the Landlord to extend the term of the lease to the Headquarters for an additional one year period (the “Extended Lease Agreement”). The one year extension will end on November 30, 2017. Pursuant to the Extended Lease Agreement, the base rent is $10,757 per month and the Company may cancel the lease with three months’ prior written notice to the Landlord at any time during the term. The Extended Lease Agreement was filed with the SEC as Exhibit 10.1 to the Company’s Quarterly Report on Form 10Q on November 9, 2016.
 
On November 8, 2016, following the change in Endo management, Endo announced as part of its earnings call that an analysis is ongoing of the XIAFLEX exercised but non-marketed indications, including frozen shoulder, cellulite, canine lipoma, lateral hip fat, plantar fibromatosis and human lipoma, so that Endo can best prioritize its R & D efforts and determine clinical trial timelines moving forward.
 
Item 2:
Management’s Discussion and Analysis of Financial Condition and Results of Operations

The following discussion should be read in conjunction with the condensed consolidated financial statements and the related notes thereto included elsewhere in this Report and is qualified by reference to them.

Overview

We are a biopharmaceutical company involved in the development of an injectable collagenase clostridium histolyticum, or CCH, for multiple indications. We currently have a development and license agreement with Endo for injectable collagenase for marketed indications and indications in development. Endo assumed this agreement when Endo acquired Auxilium. CCH is marketed as XIAFLEX® (or XIAPEX® in Europe).

The two marketed indications involving our injectable collagenase are Dupuytren’s contracture and Peyronie’s disease. Prior to the Acquisition, Auxilium had, and after the Acquisition, Endo has, opted-in to the following indications: frozen shoulder, cellulite, canine lipoma, lateral hip fat, plantar fibromatosis and human lipoma. We manage the development of CCH for uterine fibroids and initiate the development of CCH in new potential indications, not licensed by Endo.

Endo is currently selling XIAFLEX in the U.S. for the treatment of Dupuytren’s contracture and Peyronie’s disease and has an agreement with Sobi, pursuant to which Sobi has marketing rights for XIAPEX for Dupuytren’s contracture and Peyronie’s disease in Europe and certain Eurasian countries. Sobi is currently selling XIAPEX in Europe for the treatment of Dupuytren’s contracture and Peyronie’s disease. In addition, Endo has an agreement with Asahi pursuant to which Asahi has the right to commercialize XIAFLEX for the treatment of Dupuytren’s contracture and Peyronie’s disease in Japan. Asahi has received regulatory approval and is currently selling XIAFLEX for the treatment of Dupuytren’s contracture in Japan.

Operational Highlights

On July 29, 2016, Endo notified us that it was exercising its right to opt-in for the human lipoma indication, bringing their total number of licensed indications to eight. As a result of Endo's opt-in for this indication, in addition to an opt-in payment of $750,000 received in the third quarter of 2016, they are now responsible for all costs for future clinical development and will owe potential future milestone, royalty and mark-up on cost of goods payments to us.

Outlook

We generated revenue from primarily one source, the License Agreement.  Under the License Agreement, we receive license, sublicense income, royalties, milestones and mark-up on cost of goods sold payments related to the sale, regulatory submissions and approval of XIAFLEX as described above.

Significant Risks

We are dependent to a significant extent on third parties, and our principal licensee, Endo, may not be able to continue successfully commercializing XIAFLEX for Dupuytren’s contracture and Peyronie’s disease, successfully develop CCH for additional indications, obtain required regulatory approvals, manufacture XIAFLEX at an acceptable cost, in a timely manner and with appropriate quality, or successfully market products or maintain desired margins for products sold, and, as a result, we may not achieve sustained profitable operations.

The Company maintains bank account balances, which, at times, may exceed insured limits. The Company has not experienced any losses with these accounts and believes that it is not exposed to any significant credit risk on cash.  The Company maintains its investment in FDIC insured certificates of deposits with several banks, municipal bonds and corporate bonds.

For more information regarding the risks facing the Company, please see the risk factors discussed under the heading “Risk Factors” under Item 1A of Part 2 within this report and our Quarterly Reports on Form 10Q for the periods ended March 31, 2016 and June 30, 2016 filed with the SEC on May 10, 2016 and August 9, 2016, respectively, and under item 1A of Part 1 of our Annual Report on Form 10-K for the year ended December 31, 2015 filed with the SEC on March 14, 2016.
 
Critical Accounting Policies, Estimates and Assumptions

The preparation of condensed consolidated financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the condensed consolidated financial statements and the reported amounts of revenues and expenses during the reporting period. These estimates are based on historical experience and on various other assumptions that we believe are reasonable under the circumstances. The financial information at September 30, 2016 and for the three and nine months ended September 30, 2016 and 2015 is unaudited, but includes all adjustments (consisting only of normal recurring adjustments) which, in the opinion of management, are necessary to state fairly the financial information set forth herein. The December 31, 2015 balance sheet amounts and disclosures included herein have been derived from the Company’s December 31, 2015 audited consolidated financial statements. The interim results are not necessarily indicative of results to be expected for the full fiscal year. These unaudited condensed consolidated financial statements should be read in conjunction with the audited consolidated financial statements for the year ended December 31, 2015 included in the Company’s Annual Report on Form 10-K and with the unaudited condensed consolidated financial statements included in our Quarterly Reports on Form 10-Q for the first and second quarter of 2016 filed with the SEC. While our significant accounting policies are described in more detail in the notes to our unaudited condensed consolidated financial statements, we believe the following accounting policies to be critical to the judgments and estimates used in the preparation of our unaudited condensed consolidated financial statements. Actual results have differed in the past, and may differ in the future, from our estimates and could impact our earnings in any period during which an adjustment is made.

Revenue Recognition

We currently recognize revenues resulting from the licensing, sublicensing and use of our technology and from services we sometimes perform in connection with the licensed technology.

We enter into product development licenses and collaboration agreements that may contain multiple elements, such as upfront license and sublicense fees, milestones related to the achievement of particular stages in product development and royalties. As a result, significant contract interpretation is sometimes required to determine the appropriate accounting, including whether the deliverables specified in a multiple-element arrangement should be treated as separate units of accounting for revenue recognition purposes, and if deliverables should be treated as separate units, how the aggregate contract value should be allocated among the deliverable elements and when to recognize revenue for each element.

We recognize revenue for delivered elements only when the fair values of undelivered elements are known, when the associated earnings process is complete and, to the extent the milestone amount relates to our performance obligation, when our licensee confirms that we have met the requirements under the terms of the agreement, and when payment is reasonably assured. Changes in the allocation of the contract value between various deliverable elements might impact the timing of revenue recognition, but in any event, would not change the total revenue recognized on the contract. For example, nonrefundable upfront product license fees for product candidates for which we are providing continuing services related to product development are deferred and recognized as revenue over the development period.

Milestones, in the form of additional license fees, typically represent nonrefundable payments to be received in conjunction with the achievement of a specific event identified in a contract, such as completion of specified clinical development activities and/or regulatory submissions and/or approvals. We believe that a milestone represents the culmination of a distinct earnings process when it is not associated with ongoing research, development or other performance on our part. We recognize such milestones as revenue when they become due and payment is reasonably assured. When a milestone does not represent the culmination of a distinct earnings process, we recognize revenue in a manner similar to that of an upfront product license fee.

We recognize revenues from product sales in other income when there is persuasive evidence that an arrangement exists, title passes, the price is fixed and determinable, and payment is reasonably assured.
 
Royalty / Mark-up on Cost of Goods Sold

For those arrangements for which royalty and mark-up on cost of goods sold information becomes available and collectability is reasonably assured, we recognize revenue during the applicable period earned. For interim quarterly reporting purposes, when collectability is reasonably assured, but a reasonable estimate of royalty and mark-up on cost of goods sold cannot be made, the royalty and mark-up on cost of goods sold are generally recognized in the quarter that the applicable licensee provides the written report and related information to us.

Under the License Agreement, we do not participate in the selling, marketing or manufacturing of products for which we receive royalties and a mark-up on the cost of goods sold. The royalty and mark-up on cost of goods sold will generally be recognized in the quarter that Endo provides the written reports and related information to us; that is, royalty and mark-up on cost of goods sold are generally recognized one quarter following the quarter in which the underlying sales by Endo occurred. The royalties payable by Endo to us are subject to set-off for certain patent costs.

Pursuant to the First Amendment with Endo, in exchange for a $8.25 million lump sum payment, we will not receive future additional mark-up on cost of goods sold for sales by non-affiliated sublicensees of Endo outside of the U.S.; provided, however, that Endo will still be required to pay a mark-up on cost of goods sold for sales made in the “Endo Territory,” which includes sales made in the U.S. and sales made in any other country where Endo sells the product directly or through affiliated sublicensees. We received this $8.25 million lump sum payment in February 2016. We classified this payment as deferred revenue in our balance sheet and began recognizing this income over time beginning in the second quarter of 2016 based on sales by non-affiliated sublicensees of Endo outside of the U.S. according to our revenue recognition policy. We recognized approximately $274,000 and $546,000 for the three and nine months ended September 30, 2016, respectively, and zero in each of the 2015 corresponding periods.

Reimbursable Third-Party Development Costs

We accrue patent expenses for that are reimbursable by us under the License Agreement.  We capitalize certain patent costs related to estimated third-party development costs that are reimbursable under the License Agreement. As of September 30, 2016 and December 31, 2015, our estimated net reimbursable third party patent costs accrual were approximately $25,000 and $20,000, respectively.

Receivables

At September 30, 2016 and December 31, 2015 our accounts receivable balance which consists of royalties, mark-up on costs of goods sold and a portion of a milestone payment from Endo due to a foreign tax withholding, was $3.8 million and $2.5 million, respectively, and was from one customer, Endo.

Deferred Revenue

Deferred revenue consists of the mark-up on cost of goods sold for sales by non-affiliated sublicensees and will be recognized as income over time based on sales by non-affiliated sublicensees of Endo outside of the U.S in accordance with our revenue recognition policy beginning in the second quarter of 2016. In addition, deferred revenue consists of licensing fees related to the cash payments received under the License Agreement in prior years and amortized over the expected development period of certain indications for XIAFLEX and a portion of a milestone payment withheld by Endo due to a foreign tax withholding which remains uncollected. As of September 30, 2016 and December 31, 2015, deferred revenue was approximately $7.9 million and $0.2 million, respectively.

Third-Party Royalties

We have entered into licensing and royalty agreements with third parties and have agreed to pay certain royalties on net sales of products for specific indications. The royalty rates differ from agreement to agreement and, in certain cases, have been redacted with the permission of the SEC.  No assumptions should be made that any disclosed royalty rate payable to any particular third party are the same or similar with respect to any royalty rate payable to any other third parties.  We accrue third-party royalty expenses on net sales reported to us by Endo. Third-party royalty costs are generally expensed in the quarter that Endo provides the written reports and related information to us; that is, generally one quarter following the quarter in which the underlying sales by Endo occurred. For the three and nine month periods ended September 30, 2016, third-party royalty expenses were $0.4 million and $1.2 million, respectively, and for the three and nine month periods ended September 30, 2015, third-party royalty expenses were $0.3 million and $1.0 million, respectively. Our third-party royalty expense under general and administrative expenses may increase if net sales by Endo and its partners for XIAFLEX and XIAPEX increase and potential new indications for CCH are approved.
 
Royalty Buy-Down

On March 31, 2012, we entered into an amendment to our existing agreement with Dr. Martin K. Gelbard, dated August 27, 2008, related to our future royalty obligations in connection with Peyronie’s disease. The amendment enables us to buy down a portion of our future royalty obligations in exchange for an initial cash payment of $1.5 million and five additional cash payments of $600,000, three of which have been paid as of September 30, 2016.  We are currently making the payments to buy down the future royalty obligations, which royalty obligations terminate five years after first commercial sale. The Company amortizes long-term contracts with finite lives in a manner that reflects the pattern in which the economic benefits of the assets are consumed or otherwise used up. Dr. Gelbard’s agreement is amortized based on an income forecast method by estimating sales of XIAFLEX for Peyronie’s disease on an annual basis as measured by the proportion of the total estimated sales over the five year period. Related to this agreement, we amortized approximately $247,000 and $740,000 for the three and nine months ended September 30, 2016, respectively, and $221,000 and $420,000 for the three and nine months ended September 30, 2015, respectively. The remaining capitalized balance as of September 30, 2016 was $3.1 million. We perform an evaluation of the recoverability of the carrying value to determine if facts and circumstances indicate that the carrying value of the assets may be impaired and if any adjustment is warranted. Based on our evaluation as of September 30, 2016, no impairment existed and no adjustment was warranted.

Stock Based Compensation

Under ASC 718, we estimate the fair value of our employee stock option awards at the date of grant using the Black-Scholes option-pricing model, which requires the use of certain subjective assumptions. The most significant assumptions are our estimates of the expected volatility of the market price of our stock and the expected term of an option award. Expected volatility is based on the historical volatility of our common stock. When establishing an estimate of the expected term of an option award, we consider the vesting period for the award, our historical experience of employee stock option exercises (including forfeitures) and the expected volatility of our common stock. We review our estimates at each grant date and, as a result, we are likely to change our valuation assumptions used to value future employee stock-based awards granted, to the extent any such awards are granted.

Further, ASC 718 requires that employee stock-based compensation costs be recognized over the requisite service period, or the vesting period, in a manner similar to all other forms of compensation paid to employees. The allocation of employee stock-based compensation costs to each operating expense line is estimated based on specific employee headcount information at each grant date and estimated stock option forfeiture rates and are revised, if necessary, in future periods if actual employee headcount information or forfeitures differ materially from those estimates. As a result, the amount of employee stock-based compensation costs we recognize in each operating expense category in future periods may differ significantly from what we have recorded in the current period.

RESULTS OF OPERATIONS

THREE MONTHS ENDED SEPTEMBER 30, 2016 COMPARED TO THREE MONTHS ENDED SEPTEMBER 30, 2015

Revenues

Royalties

Royalties consist of royalties and the mark-up on cost of goods sold under the License Agreement. Total royalty and mark-up on cost of goods sold for the three month period ended September 30, 2016 were $6.1 million as compared to $5.3 million in the corresponding 2015 period, an increase of $0.8 million or 15%. This increase in royalties and the mark-up on cost of goods sold was primarily due to the increase in sales of XIAFLEX for the treatment of Dupuytren’s contracture and Peyronie’s disease.

Licensing Revenue
Licensing revenue consists of licensing fees, sublicensing fees and milestones. We recognized licensing fees related to the exercise of an opt-in right by Endo for the human lipoma indication of $750,000 for the three months ended September 30, 2016 as compared to zero in the corresponding 2015 period. In addition, we recognized certain licensing fees related to the cash payments received under the Auxilium Agreement in prior years and amortized them over the expected development period. For each of the three month periods ended September 30, 2016 and 2015, we recognized licensing revenue related to the development of injectable collagenase of approximately $12,000.
 
Milestone revenue recognized for the three months ended September 30, 2016 was zero as compared to $1.0 million for the corresponding 2015 period.  The $1.0 million milestone revenue recognized in the corresponding 2015 period related to the first commercial sale of XIAFLEX by Asahi for the treatment of Dupuytren's contracture in Japan.
 
Research and Development Activities and Expenses
 
R&D expenses include, but are not limited to, internal costs, such as salaries and benefits, costs of materials, lab expenses, facility costs and overhead. R&D expenses also consist of third party costs, such as medical professional fees, product costs used in clinical trials, consulting fees, and costs associated with clinical study arrangements. For each of the three months ended September 30, 2016 and 2015, R&D expenses were $0.3 million and are primarily related to the development work associated with our clinical programs, preclinical and other R&D programs.

We manage the development of CCH for uterine fibroids and initiate the development of CCH in new potential indications, not licensed by Endo. We have finished the development work on human lipomas.  On July 29, 2016, Endo exercised its opt-in right under the license agreement with respect to the human lipoma indication.
 
The following table summarizes our R&D expenses related to our development programs:
 
   
Three Months Ended
September 30, 2016
   
Three Months Ended
September 30, 2015
 
Program
           
Human Lipoma
 
$
100,973
   
$
68,606
 
Uterine Fibroids
   
18,762
     
19,915
 
Pre-clinical/other research projects
   
193,172
     
170,316
 
 
The successful development of drugs is inherently difficult and uncertain.  Our business requires investments in R&D over many years, often for drug candidates that may fail during the R&D process. Even if the Company is able to successfully complete the development of our drug candidates, our long-term prospects depend upon our ability and the ability of our partners, particularly with respect to XIAFLEX and CCH, to continue to successfully commercialize these drug candidates.

There is significant uncertainty regarding our ability to successfully develop drug candidates in other indications. These risks include the uncertainty of:
 
·
the nature, timing and estimated costs of the efforts necessary to complete the development of our drug candidate projects;

·
the anticipated completion dates for our drug candidate projects;

·
the scope, rate of progress and cost of our clinical trials that we are currently running or may commence in the future with respect to our drug candidate projects;

·
the scope, rate of progress of our preclinical studies and other R&D activities related to our drug candidate projects;

·
the clinical trial results for our drug candidate projects;

·
the cost of filing, prosecuting, defending and enforcing any patent claims and other intellectual property rights relating to our drug candidate projects;

·
the terms and timing of any strategic alliance, partnership, joint venture, licensing and other arrangements that we have or may establish in the future relating to our drug candidate projects;

·
the cost and timing of regulatory approvals with respect to our drug candidate projects; and

·
the cost of establishing clinical supplies for our drug candidate projects.
 
We believe that our current resources and liquidity are sufficient to advance our significant current clinical and R&D projects.

General and Administrative Expenses

General and administrative expenses consist primarily of salaries and other related costs for personnel, third-party royalty fees, amortization of deferred royalty buy-down, consultant costs, legal fees, investor relations, professional fees and overhead costs. General and administrative expenses for the three months ended September 30, 2016 and 2015 were $1.8 million and $1.7 million, respectively. The increase in general and administrative expenses was mainly due to the increased amortization of the deferred royalty buy-down, third party royalty and consulting fees.

Other Income

Other income for the three months ended September 30, 2016 was approximately $87,000 compared to $28,000 in the corresponding 2015 period. Other income consists of interest earned on our investments and product sales of collagenase for laboratory use.

Provision for Income Taxes

Our deferred tax liabilities and deferred tax assets are impacted by events and transactions arising in the ordinary course of business, R&D activities, vesting of nonqualified options, deferred revenues and other items. The provision for income taxes is based on an estimated effective tax rate derived from an estimate of condensed consolidated earnings before taxes, adjusted for nondeductible expenses and other permanent differences for the fiscal year.

For the three month period ended September 30, 2016, our provision for income taxes was $1.8 million. Our taxes payable as of September 30, 2016 were reduced by $0.2 million due to the windfall associated with the disqualified sale of incentive stock options and the exercise of nonqualified options. Our deferred tax assets remained unchanged as of September 30, 2016.
 
For the three month period ended September 30, 2015, the provision for income taxes was $1.5 million.
 
Net Income

For the three months ended September 30, 2016, we recorded net income of $3.1 million, or $0.43 per basic common share and $0.42 per diluted common share, compared to a net income of $2.9 million, or $0.42 per basic common share and $0.39 per diluted common share, for the same period in 2015.

NINE MONTHS ENDED SEPTEMBER 30, 2016 COMPARED TO NINE MONTHS ENDED SEPTEMBER 30, 2015

Revenues

Royalties

Royalties consist of royalties and the mark-up on cost of goods sold under the License Agreement. Total royalty and mark-up on cost of goods sold for the nine month period ended September 30, 2016 were $18.8 million as compared to $15.6 million in the corresponding 2015 period, an increase of $3.2 million or 21%. This increase in royalties and the mark-up on cost of goods sold was primarily due to the increase in sales of XIAFLEX for the treatment of Dupuytren’s contracture and Peyronie’s disease.

Licensing Revenue
 
Licensing revenue consists of licensing fees, sublicensing fees and milestones. We recognized licensing fees related to the exercise of an opt-in right by Endo for the human lipoma indication of $750,000 for the nine months ended September 30, 2016 as compared to zero in the corresponding 2015 period. In addition, we recognized certain licensing fees related to the cash payments received under the Auxilium Agreement in prior years and amortized them over the expected development period. For each of the nine month periods ended September 30, 2016 and 2015, we recognized licensing revenue related to the development of injectable collagenase of approximately $37,000.
 
Milestone revenue recognized for the nine months ended September 30, 2016 was zero as compared to $1.0 million for the corresponding 2015 period.  The $1.0 million milestone revenue recognized in the corresponding 2015 period related to the first commercial sale of XIAFLEX by Asahi for the treatment of Dupuytren's contracture in Japan.
 
Research and Development Activities and Expenses
 
R&D expenses include, but are not limited to, internal costs, such as salaries and benefits, costs of materials, lab expenses, facility costs and overhead. R&D expenses also consist of third party costs, such as medical professional fees, product costs used in clinical trials, consulting fees and costs associated with clinical study arrangements. For the nine months ended September 30, 2016 and 2015, R&D expenses were $1.0 million and $0.8 million, respectively. This increase is primarily related to the development work associated with our clinical programs, preclinical and other R&D programs.

We manage the development of CCH for uterine fibroids and initiate the development of CCH in new potential indications, not licensed by Endo. We have finished the development work on human lipomas.  On July 29, 2016, Endo exercised its opt-in right under the license agreement with respect to the human lipoma indication.
 
The following table summarizes our R&D expenses related to our development programs:
 
   
Nine Months Ended
September 30, 2016
   
Nine Months Ended
September 30, 2015
 
Program
           
Human Lipoma
 
$
352,073
   
$
193,704
 
Uterine Fibroids
   
111,782
     
26,858
 
Pre-clinical/other research projects
   
542,029
     
534,476
 

The successful development of drugs is inherently difficult and uncertain.  Our business requires investments in R&D over many years, often for drug candidates that may fail during the R&D process. Even if the Company is able to successfully complete the development of our drug candidates, our long-term prospects depend upon our ability and the ability of our partners, particularly with respect to XIAFLEX and CCH, to continue to successfully commercialize these drug candidates.

There is significant uncertainty regarding our ability to successfully develop drug candidates in other indications. These risks include the uncertainty of:
 
·
the nature, timing and estimated costs of the efforts necessary to complete the development of our drug candidate projects;

·
the anticipated completion dates for our drug candidate projects;

·
the scope, rate of progress and cost of our clinical trials that we are currently running or may commence in the future with respect to our drug candidate projects;

·
the scope, rate of progress of our preclinical studies and other R&D activities related to our drug candidate projects;

·
the clinical trial results for our drug candidate projects;

·
the cost of filing, prosecuting, defending and enforcing any patent claims and other intellectual property rights relating to our drug candidate projects;

·
the terms and timing of any strategic alliance, partnership, joint venture, licensing and other arrangements that we have or may establish in the future relating to our drug candidate projects;

·
the cost and timing of regulatory approvals with respect to our drug candidate projects; and

·
the cost of establishing clinical supplies for our drug candidate projects.
 
We believe that our current resources and liquidity are sufficient to advance our significant current clinical and R&D projects.

General and Administrative Expenses

General and administrative expenses consist primarily of salaries and other related costs for personnel, third-party royalty fees, amortization of deferred royalty buy-down, consultant costs, legal fees, investor relations, professional fees and overhead costs. General and administrative expenses for the nine months ended September 30, 2016 and 2015 were $5.9 million and $5.3 million, respectively. The increase in general and administrative expenses was mainly due to the increased amortization of the deferred royalty buy-down, third party royalty, patent fees, director fees and stock-based compensation partially offset by lower legal and consulting fees.

Other Income

Other income for the nine months ended September 30, 2016 was approximately $238,000 compared to $65,000 in the corresponding 2015 period. Other income consists of interest earned on our investments and product sales of collagenase for laboratory use.

Provision for Income Taxes

Our deferred tax liabilities and deferred tax assets are impacted by events and transactions arising in the ordinary course of business, R&D activities, vesting of nonqualified options, deferred revenues and other items. The provision for income taxes is based on an estimated effective tax rate derived from an estimate of condensed consolidated earnings before taxes, adjusted for nondeductible expenses and other permanent differences for the fiscal year.
For the nine month period ended September 30, 2016, our provision for income taxes was $4.5 million. Our taxes payable as of September 30, 2016 were reduced by $0.2 million due to the windfall associated with the disqualified sale of incentive stock options and the exercise of nonqualified options. Our deferred tax assets increased by $2.7 million due to the deferred revenue associated with the receipt of $8.25 million under the First Amendment with Endo on sales by non-affiliated sublicensees of Endo outside of the U.S. As of September 30, 2016, our remaining deferred tax assets were approximately $3.4 million.
For the nine month period ended September 30, 2015, the provision for income taxes was $3.7 million.

Net Income

For the nine months ended September 30, 2016, we recorded net income of $8.5 million, or $1.20 per basic common share and $1.16 per diluted common share, compared to a net income of $7.0 million, or $1.02 per basic common share and $0.96 per diluted common share, for the same period in 2015.

Liquidity and Capital Resources

To date, we have financed our operations primarily through product sales, licensing revenues and royalties under agreements with third parties and sales of our common stock. At September 30, 2016 and December 31, 2015, we had cash and cash equivalents and investments in the aggregate of approximately $51.3 million and $37.1 million, respectively. We currently anticipate that our available funds and cash flow from operations will be sufficient to meet our operational cash needs for at least the next 12 months.

Net cash provided by operating activities for the nine months ended September 30, 2016 and 2015 was $14.8 million and $6.2 million, respectively. Net cash provided by operating activities in the 2016 period was primarily attributable to our net income of $8.5 million, an increase in operating assets and liabilities of $7.8 million of which $7.7 million was related to the First Amendment with Endo for mark-up on cost of goods sold for sales by non-affiliated sublicensees of Endo outside of the U.S. Non-cash items included amortization, stock-based compensation expense, and deferred taxes which was reduced by adjustments to reconcile net income to net cash provided by operating activities of $1.4 million. Net cash provided by operating activities in the 2015 period was primarily attributable to our net income of $7.0 million, adjustments to reconcile net income to net cash provided by operating activities of $1.2 million and changes in operating assets and liabilities of $1.9 million. Non-cash items included amortization, stock-based compensation expense, deferred taxes and deferred revenue.
 
Net cash used in investing activities for the nine months ended September 30, 2016 was $15.0 million as compared to $13.4 million for the corresponding 2015 period. The net cash used in investing activities in the 2016 period reflects the maturing of $32.5 million and investment of $47.6 million in marketable securities. The net cash used in investing activities in the 2015 period reflects the maturing of $11.0 million and investment of $24.4 million in marketable securities.

Net cash used in financing activities for the nine months ended September 30, 2016 was $0.1 million as compared to net cash provided by financing activities of $4.8 million in the corresponding 2015 period. In the 2016 period, net cash used in financing activities was mainly due to the repurchase of $0.9 million of our common stock under our stock repurchase program partially offset by the excess tax benefits related to share-based payments of $0.2 million and the proceeds received from stock option exercises of approximately $0.5 million. In the 2015 period, net cash provided by financing activities was mainly due to the excess tax benefits related to share-based payments of $3.2 million and the proceeds received from stock option exercises of approximately $2.8 million partially offset by the repurchase of $1.2 million of our common stock under our stock repurchase program.

Off-Balance Sheet Arrangements

We do not have any off-balance sheet arrangements as defined in Item 303(a)(4) of Regulation S-K.

Item 3:
Quantitative and Qualitative Disclosures About Market Risk

We do not use derivative financial instruments or derivative commodity instruments for trading purposes. Our financial instruments consist of cash, cash equivalents, investments, trade accounts receivable, accounts payable and long-term obligations. We consider investments that, when purchased, have a remaining maturity of three months or less to be cash equivalents.

Our investment portfolio is subject to interest rate risk, although limited given the short term nature of the investments, and will fall in value in the event market interest rates increase. All of our cash and cash equivalents and investments at September 30, 2016, amounting to approximately $51.3 million, were maintained in bank demand accounts, money market accounts, certificates of deposit, corporate bonds and municipal bonds. We do not hedge our interest rate risks, as we believe reasonably possible near-term changes in interest rates would not materially affect our results of operations, financial position or cash flows.

We are subject to market risks in the normal course of our business, including changes in interest rates. There have been no significant changes in our exposure to market risks since December 31, 2015.

Item 4:
Controls and Procedures

Evaluation of Disclosure Controls and Procedures

The Company, under the supervision and with the participation of Thomas L. Wegman, the Company’s President, Principal Executive Officer and Principal Financial Officer, evaluated the effectiveness of its disclosure controls and procedures as of the end of the period covered by this Quarterly Report on Form 10-Q. Based on that evaluation, Thomas L. Wegman, in his capacity as the sole named executive officer of the Company, the Company’s Principal Executive Officer and the Company’s Principal Financial Officer, concluded that the Company’s disclosure controls and procedures are effective to ensure that information required to be disclosed by it in reports the Company files or submits under the Securities Exchange Act of 1934, as amended (the “Exchange Act”), is recorded, processed, summarized and reported within the time periods specified in the rules and forms of the SEC, and that such material information is accumulated and communicated to the Company’s management, including its Principal Executive Officer and Principal Financial Officer, to allow timely decisions regarding required disclosure. Because of the inherent limitations in all control systems, any controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving the desired control objectives, and management necessarily is required to apply its judgment in evaluating the cost-benefit relationship of possible controls and procedures. Furthermore, the Company’s controls and procedures can be circumvented by the individual acts of some persons, by collusion of two or more people or by management override of such control, and misstatements due to error or fraud may occur and not be detected on a timely basis.
 
Changes in Internal Controls

There were no changes in our internal controls over financial reporting during the quarter ended September 30, 2016 that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

PART II: OTHER INFORMATION

Item 1.
Legal Proceedings

None.

Item 1A.
Risk Factors
 
The outcome and effects of Endo’s ongoing analysis of the XIAFLEX exercised but non-marketed indications is uncertain.
 
Following the change in Endo management, Endo has announced an analysis of the XIAFLEX exercised but non-marketed indications, including frozen shoulder, cellulite, canine lipoma, lateral hip fat, plantar fibromatosis and human lipoma, so that Endo can best prioritize its R & D efforts and determine clinical trial timelines moving forward.  At the present time, it is unclear how long this analysis will take to complete and the effect that it will have on Endo’s willingness to develop further such exercised but non-marketed indications.  It is also unclear what effect, if any, the analysis will have on the willingness of Endo to exercise its rights to opt in for any additional indications, including uterine fibroid, currently under development by the Company.
 
In addition to the other information contained elsewhere in this Report, you should carefully consider the risk factors discussed in “Part I, Item 1A. Risk Factors” in our Quarterly Report on Form 10-Q for the periods ended March 31, 2016 and June 30, 2016 filed with the SEC on May 10, 2016 and August 9, 2016, respectively, and our Annual Report on Form 10-K for the period ended December 31, 2015 filed with the SEC on March 4, 2016, which could materially affect our business, financial condition or future results.

Item 2.
Unregistered Sales of Equity Securities and Use of Proceeds
During the nine month period ended September 30, 2016, we did not issue any unregistered equity securities.

Issuer Purchases of Equity Securities

The following table presents a summary of share repurchases made by us during the quarter ended September 30, 2016.

Period
 
Total Number of
Shares
Purchased (2)
   
Average
Price Paid
Per Share (3)
   
Total Number of
Shares
Purchased as
Part of Publicly
Announced Plan
   
Maximum
Number (or
Dollar Value) of
Shares that may
yet be Purchased
under the Plan
 
                     
$
927,193
(1) 
July 1, 2016 – July 31, 2016
   
1,655
   
$
40.62
     
256,053
     
859,969
 
August 1, 2016 – August 31, 2016
   
2,235
     
38.66
     
258,288
     
773,563
 
September 1, 2016 – September 30, 2016
   
1,400
     
36.84
     
259,688
     
721,986
 

(1)
On August 17, 2015, we announced that our Board of Directors had authorized the repurchase of up to $2.5 million of our common stock under the stock repurchase program.
(2)
The purchases were made in open-market transactions in compliance with rule 10b-18 or under the company’s 10b-18 plan.
(3)
Includes commissions paid, if any, related to the stock repurchase transactions.

Item 6.
Exhibits

 
Amended Agreement of Lease, dated as of November 1, 2016, among the Company, ABC-NY and 35 Wilbur Street Associates.
 
Certification of Principal Executive Officer and Principal Financial Officer pursuant to Rule13a-14(a)/15d-14(a).
 
Certification of Principal Executive Officer and Principal Financial Officer pursuant to Section 906 of Sarbanes-Oxley Act of 2002.
 
101*
The following materials from BioSpecifics Technologies Corp.’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2016, (ii) the Condensed Consolidated Statements of Operations, (iii) the Condensed Consolidated Statements of Cash Flows, and (iv) the Notes to the Condensed Consolidated Financial Statements.
 

* filed herewith
** furnished herewith
 
SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this Report to be signed on its behalf by the undersigned thereunto duly authorized.

 
BIOSPECIFICS TECHNOLOGIES CORP.
 
(Registrant)
   
Date: November 9, 2016
/s/ Thomas L. Wegman
 
Thomas L. Wegman
 
President, Principal Executive Officer and
Principal Financial Officer
 
 
27

EX-10.1 2 ex10_1.htm EXHIBIT 10.1

Exhibit 10.1

35 Wilbur Street Associates, LLC
19 Wilbur Street
Lynbrook, NY 11563

November 1, 2016

Mr. Thomas Wegman
Advance Biofactures Corp.
35 Wilbur Street
Lynbrook, NY 11563

Re:
Lease dated November 21, 2013 between 35 Wilbur Street Assoc., LLC and Advance Biofactures Corp., premises; 35 Wilbur Street, Lynbrook, NY 11563.

Dear Mr. Wegman:

It is our understanding that you would like to renew the lease.  The current lease expires on November 30, 2016. We propose that the current terms of the lease remain in effect except where the following is concerned:

1)
The landlord will take occupancy of additional warehouse space in the rear of the building as discussed and agreed.
2)
The lease will be renewed for 1 (one) year at the rate of $129,082 annually. $10,756.83/ month.
3)
This will be less 14.89% of the utilities.
4)
The proposed warehouse space must be delivered to the landlord empty and broom clean.
5)
The Tenant has the option to cancel this lease, without penalty, by providing the Landlord with three (3) months prior notice at any time during the Term of this lease.

A current copy of the certificate of liability insurance is included.

Sincerely yours,
 
Valorie Mancuso
Controller
 
Thomas Wegman, President
 
Richard Arote
Advance Biofactures Corp.
 
35 Wilbur Street Assoc., LLC
     
/S/ Thomas Wegman
 
/S/ Richard Arote
 
State of New York
 
ss:
County of Nassau
   
On this           1st           day of November , 2015, before me personally came,           Thomas Wegman          to me known, who, being by me duly sworn, did say that he is the President of Advance Biofactures Corp. and that he signed his name thereto by authority of the board of directors.

/S/ Helen L. Piazza
 
 
 


EX-31 3 ex31.htm EXHIBIT 31

Exhibit 31

CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER AND PRINCIPAL FINANCIAL OFFICER
 PURSUANT TO RULES 13a-14(a) AND 15d-14(a) OF
 THE SECURITIES EXCHANGE ACT OF 1934

I, Thomas L. Wegman, certify that:

1.
I have reviewed this report on Form 10-Q for the quarterly period ended September 30, 2016 of BioSpecifics Technologies Corp.;

2.
Based on my knowledge, the report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3.
Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4.
The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

(a)
Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b)
Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c)
Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d)
Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and
 
5.
The registrant’s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a)
All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b)
Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal controls over financial reporting.

Date: November 9, 2016
 
   
/s/ Thomas L. Wegman
 
 Thomas L. Wegman
 
 President, Principal Executive Officer and Principal Financial Officer
 
 

EX-32 4 ex32.htm EXHIBIT 32

Exhibit 32

CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER AND PRINCIPAL FINANCIAL OFFICER
 PURSUANT TO RULES 13a-14(b) AND 15d-14(b) OF
 THE SECURITIES EXCHANGE ACT OF 1934 AND
 18 U.S.C. SECTION 1350, AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

The undersigned, Thomas L. Wegman, the President, Principal Executive Officer and Principal Financial Officer of BioSpecifics Technologies Corp. (the “Company”), DOES HEREBY CERTIFY that:

1.
The Company’s report on Form 10-Q for the quarterly period ended September 30, 2016 (the “Report”), fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended (the “Exchange Act); and

2.
The information contained in the Report fairly presents, in all material respects, the financial condition and results of operation of the Company.

IN WITNESS WHEREOF, the undersigned has executed this certification this 9th day of November, 2016.

/s/ Thomas L. Wegman
 
 Thomas L. Wegman
 
 President, Principal Executive Officer and Principal Financial Officer

This certification shall not be deemed “filed” for purposes of Section 18 of the Exchange Act or otherwise subject to liability pursuant to that section. Such certification shall not be deemed to be incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act, except to the extent that the Company specifically incorporates it by reference.

A signed original of this written statement required by Section 906 has been provided to the Company and will be retained by the Company and furnished to the Securities and Exchange Commission or its staff upon request.
 
 

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text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; 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font-family: 'Times New Roman'; width: 90%;"><tr><td valign="bottom" style="vertical-align: top; padding-bottom: 2px; width: 21%;"><div style="font-size: 10pt; font-family: 'Times New Roman'; font-variant: normal; font-weight: bold; font-style: normal; text-align: left;"><u>September 30, 2016</u></div></td><td valign="bottom" style="vertical-align: top; padding-bottom: 2px; width: 21%;"><div style="font-size: 10pt; font-family: 'Times New Roman'; font-variant: normal; font-weight: bold; font-style: normal; text-align: left;"><u>Type of Instrument</u></div></td><td valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; width: 1%;">&#160;</td><td colspan="2" nowrap="nowrap" valign="bottom" style="vertical-align: top; border-bottom: #000000 2px solid;"><div></div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: center;">Fair Value</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; text-align: left; width: 1%;">&#160;</td><td valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; width: 1%;">&#160;</td><td colspan="2" nowrap="nowrap" valign="bottom" style="vertical-align: top; border-bottom: #000000 2px solid;"><div></div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: center;">Level 1</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; text-align: left; width: 1%;">&#160;</td><td valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; width: 1%;">&#160;</td><td colspan="2" nowrap="nowrap" valign="bottom" style="vertical-align: top; border-bottom: #000000 2px solid;"><div></div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: center;">Level 2</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; padding-bottom: 2px; text-align: left; width: 1%;">&#160;</td><td valign="bottom" style="vertical-align: bottom; 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text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td></tr><tr><td valign="bottom" style="vertical-align: top; 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text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; 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font-size: 10pt;"><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: left;">New Accounting Pronouncements</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify; background-color: #ffffff;"><font style="font-size: 10pt; font-family: 'Times New Roman'; background-color: #ffffff;">The Financial Accounting Standards Board, or FASB</font><font style="font-size: 10pt; font-family: 'Times New Roman';">, issued in May 2014, in August 2015, March 2016 and April 2016,</font> respectively, <font style="font-size: 10pt; font-family: 'Times New Roman';">Accounting Standards Updates No. 2014-09, No. 2015-14, No. 2016-08, and No. 2016-10 (the &#8220;ASUs&#8221;). 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We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.</font></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify; background-color: #ffffff;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">In January 2016, the FASB issued new guidance on recognition and measurement of financial assets and financial liabilities. 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This guidance will be effective for us on January 1, 2018. 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We are currently evaluating this guidance and the impact it will have on the consolidated financial statements and related disclosures.</div><div><br /></div></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">In May 2016, FASB issued ASU No. 2016-12, Revenue from Contracts with Customers (Topic 606): Narrow-Scope Improvements and Practical Expedients, which is intended to not change the core principle of the guidance in Topic 606, but rather affect only the narrow aspects of Topic 606 by reducing the potential for diversity in practice at initial application and by reducing the cost and complexity of applying Topic 606 both at transition and on an ongoing basis. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">In June 2016, FASB issued ASU 2016-13, Financial Instruments - Credit Losses. The amendment revises the impairment model to utilize an expected loss methodology in place of the currently used incurred loss methodology, which will result in more timely recognition of losses on financial instruments, including, but not limited to, available for sale debt securities and accounts receivable. The Company is required to adopt this standard starting in the first quarter of fiscal year 2021. Early adoption is permitted. We are currently evaluating the impact of the adoption of this standard on our consolidated financial statements and related disclosures.</div></div> 238152 65056 86928 28221 10548799 4725885 4321958 12714638 <div style="font-family: 'Times New Roman'; font-size: 10pt;"><div style="text-align: justify;"><table cellpadding="0" cellspacing="0" class="DSPFListTable" style="font-size: 10pt; font-family: 'Times New Roman'; width: 100%;"><tr><td style="font-size: 10pt; font-family: 'Times New Roman'; vertical-align: top; font-weight: bold; width: 18pt; align: right;">1.</td><td style="vertical-align: top; text-align: justify; width: auto;"><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold;">ORGANIZATION AND DESCRIPTION OF BUSINESS</div></td></tr></table></div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">We are a biopharmaceutical company involved in the development of an injectable collagenase clostridium histolyticum, or CCH, for multiple indications. We currently have a development and license agreement with Endo Global Ventures International plc (together with Endo International plc, an affiliate of Endo Global Ventures, &#8220;Endo&#8221;) for injectable collagenase for marketed indications and indications in development. Endo assumed this agreement when Endo acquired Auxilium Pharmaceuticals, Inc. (&#8220;Auxilium&#8221;) on January 29, 2015 (the &#8220;Acquisition&#8221;).&#160; CCH is marketed as XIAFLEX&#174; (or XIAPEX&#174; in Europe).</div><div><br /></div><div style="background-color: #ffffff;"><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">On February 5, 2016, we announced that we had entered into with Endo the First Amendment (the &#8220;First Amendment&#8221;) to the Second Amended and Restated Development and Licensing Agreement (the &#8220;Auxilium Agreement&#8221;), by and between us and Auxilium, now a wholly-owned subsidiary of Endo, to amend certain provisions of the Auxilium Agreement (as amended by the First Amendment, the &#8220;License Agreement&#8221;). The effective date of the First Amendment was January 1, 2016. Pursuant to the First Amendment, we and Endo mutually agreed that in exchange for a $8.25 million lump sum payment, we will not receive future additional mark-up on cost of goods sold for sales by non-affiliated sublicensees of Endo outside of the U.S.; provided, however, that Endo will still be required to pay a mark-up on cost of goods sold for sales made in the "Endo Territory," which includes sales made in the U.S. and sales made in any other country where Endo sells the product directly or through affiliated sublicensees. We received this $8.25 million lump sum payment in February 2016 and began recognizing this income over time based on sales by non-affiliated sublicensees of Endo outside of the U.S. according to our revenue recognition policy in the second quarter of 2016.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">Additionally, we agreed that Endo may opt-in early to indications, prior to our submission of a clinical trial report, with our consent, such consent not to be unreasonably withheld. For early opt-ins, Endo will be required to make an opt-in payment of $0.5 million on a per indication basis. For regular opt-ins, following our submission of a clinical trial report, Endo will be required to make an opt-in payment of $0.75 million on a per indication basis.</div></div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">The two marketed indications involving our injectable collagenase are Dupuytren&#8217;s contracture and Peyronie&#8217;s disease. 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Machinery and equipment, furniture and fixtures, and autos are depreciated on a straight-line basis over their estimated useful lives of five to ten years. Leasehold improvements are amortized over the lesser of their estimated useful lives or the remaining life of the lease. As of September 30, 2016 and December 31, 2015, respectively, property and equipment were fully depreciated.</div></div> 755038 312907 258837 1005884 <div style="font-family: 'Times New Roman'; font-size: 10pt;"><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">R&amp;D Expenses</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">R&amp;D<font style="font-size: 10pt; font-family: 'Times New Roman';"> expenses </font>include, but are not limited to, internal costs, such as salaries and benefits, costs of materials, lab expenses, facility costs and overhead. R&amp;D expenses also consist of third party costs, such as medical professional fees, product costs used in clinical trials, consulting fees and costs associated with clinical study arrangements. We may fund R&amp;D at medical research institutions under agreements that are generally cancelable. 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Accounting Standards Codification 718, <font style="font-size: 10pt; font-family: 'Times New Roman'; font-style: italic;">Compensation - Stock Compensation </font>(&#8220;ASC 718&#8221;), requires the recognition of compensation expense, using a fair-value based method, for costs related to all stock options including stock options and common stock issued to our employees and directors under our stock plans. ASC 718 requires companies to estimate the fair value of stock option awards on the date of grant using an option-pricing model. The value of the portion of the award that is ultimately expected to vest is recognized as expense on a straight-line basis over the requisite service periods in our condensed<font style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold;">&#160;</font>consolidated statements of operations.</div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">&#160;</div><div>Under ASC 718, we estimate the fair value of our employee stock option awards at the date of grant using the Black-Scholes option-pricing model, which requires the use of certain subjective assumptions. The most significant of these assumptions are our estimates of the expected volatility of the market price of our stock and the expected term of an award. When establishing an estimate of the expected term of an option award, we consider the vesting period for the award, our recent historical experience of employee stock option exercises (including forfeitures) and the expected volatility of our common stock.&#160; As required under the accounting rules, we review our estimates at each grant date and, as a result, the valuation assumptions that we use to value employee stock-based awards granted in future periods may change. <font style="font-size: 10pt; font-family: 'Times New Roman';">No stock options were granted</font> during the nine months ended September 30, 2016 and 2015.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">Further, ASC 718 requires that employee stock-based compensation costs be recognized over the requisite service period, or the vesting period, in a manner similar to all other forms of compensation paid to employees. The allocation of employee stock-based compensation costs to each operating expense line are estimated based on specific employee headcount information at each grant date and estimated stock option forfeiture rates and revised, if necessary, in future periods if actual employee headcount information or forfeitures differ materially from those estimates. 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Although we believe that the disclosures in our financial statements are adequate to make the information presented not misleading, certain information normally included in financial statements prepared in accordance with U.S. generally accepted accounting principles (&#8220;U.S. GAAP&#8221;) has been condensed or omitted pursuant to the rules and regulations of the Securities and Exchange Commission (the &#8220;SEC&#8221;) for quarterly reporting.</div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">&#160;</div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">The information included in this Report should be read in conjunction with the risk factors discussed in &#8220;Part I, Item 1A. 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These tiers are as follows: Level 1, defined as observable inputs such as quoted market prices in active markets; Level 2, defined as inputs other than the quoted prices in active markets that are either directly or indirectly observable; and Level 3, defined as significant unobservable inputs (entity developed assumptions) in which little or no market data exists.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">As of September 30, 2016, the Company held certain investments that are required to be measured at fair value on a recurring basis. 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text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td></tr><tr><td valign="bottom" style="vertical-align: top; width: 21%; background-color: #cceeff;"><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: left;">Investments</div></td><td valign="bottom" style="vertical-align: top; width: 21%; background-color: #cceeff;"><div style="font-size: 10pt; font-family: 'Times New Roman'; 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text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: right; width: 9%; background-color: #ffffff;">&#160;</td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td><td valign="bottom" style="vertical-align: bottom; 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The Company has not experienced any losses with these accounts and believes that it is not exposed to any significant credit risk on cash.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">The Company maintains its investment in FDIC insured certificates of deposits with several banks, pre-refunded municipal bonds, municipal bonds and corporate bonds.</div><div style="text-align: justify;"><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">The Company is currently dependent on one customer, Endo, who generates almost all its revenues. For the three and nine months ended September 30, 2016, licensing, sublicensing, milestones and royalty revenues under the License Agreement with Endo were approximately $6.9 million and $19.6 million, respectively, and for the three and nine months ended September 30, 2015, the licensing, sublicensing, milestones and royalty revenues under the License Agreement with Endo were approximately $6.3 million and $16.6 million, respectively.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">At September 30, 2016 and December 31, 2015, our accounts receivable balances were $3.8 million and $2.5 million, respectively.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: left;">Revenue Recognition</div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: left;">&#160;</div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">We currently recognize revenues resulting from the licensing and sublicensing of the use of our technology and from services we sometimes perform in connection with the licensed technology under the guidance of Accounting Standards Codification 605, <font style="font-size: 10pt; font-family: 'Times New Roman'; font-style: italic;">Revenue Recognition</font> (&#8220;ASC 605&#8221;).</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">If we determine that separate elements exist in a revenue arrangement under ASC 605, we recognize revenue for delivered elements only when the fair values of undelivered elements are known, when the associated earnings process is complete, when payment is reasonably assured and, to the extent the milestone amount relates to our performance obligation, when our customer confirms that we have met the requirements under the terms of the agreement.</div><div>&#160;</div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; font-style: italic; text-align: left;"><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: normal; font-style: normal; text-align: justify;">Revenues, and their respective treatment for financial reporting purposes, are as follows:</div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: normal; text-align: justify;">&#160;</div></div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; font-style: italic; text-align: justify; text-indent: 36pt;">Royalty / Mark-Up on Cost of Goods Sold</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">For those arrangements for which royalty and mark-up on cost of goods sold information becomes available and collectability is reasonably assured, we recognize revenue during the applicable period in which it is earned. For interim quarterly and year-end reporting purposes, when collectability is reasonably assured, but a reasonable estimate of royalty and mark-up on cost of goods sold cannot be made, the royalty and mark-up on cost of goods sold are generally recognized in the quarter that the applicable licensee provides the written report and related information to us.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">Under the License Agreement, we do not participate in the selling, marketing or manufacturing of products for which we receive royalties and a mark-up on the cost of goods sold. The royalty and mark-up on cost of goods sold will generally be recognized in the quarter that Endo provides the written reports and related information to us; that is, royalty and mark-up on cost of goods sold are generally recognized one quarter following the quarter in which the underlying sales by Endo occurred.<font style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold;">&#160;</font>The royalties payable by Endo to us are subject to set-off for certain patent costs.</div><div style="background-color: #ffffff;"><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;"><font style="font-size: 10pt; font-family: 'Times New Roman';">Pursuant to the First Amendment with Endo, in exchange for a $8.25 million lump sum payment, we will not receive future additional mark-up on cost of goods sold for sales by non-affiliated sublicensees of Endo outside of the U.S.; provided, however, that Endo will still be required to pay a mark-up on cost of goods sold for sales made in the &#8220;Endo Territory,&#8221; which includes sales made in the U.S. and sales made in any other country where Endo sells the product directly or through affiliated sublicensees. We received this $8.25 million lump sum payment in February 2016. We classified this payment as deferred revenue in our balance sheet and </font>began recognizing this income over time in the second quarter of 2016 based on sales by non-affiliated sublicensees of Endo outside of the U.S. according to our revenue recognition policy. 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We recognized licensing fees related to the exercise of an opt-in right by Endo <font style="font-size: 10pt; font-family: 'Times New Roman'; background-color: #ffffff;">for the human lipoma indication</font> of $750,000 for the three and nine months ended September 30, 2016 as compared to zero in each of the 2015 periods. Nonrefundable upfront technology license fees for product candidates for which we are providing continuing services related to product development are deferred and recognized as revenue over the development period. <font style="font-size: 10pt; font-family: 'Times New Roman';">We recognized deferred revenue of $12,345 and $37,034 for the three and nine months ended </font>September<font style="font-size: 10pt; font-family: 'Times New Roman';"> 30, 2016, respectively, and $12,345 and $37,034 for the three and nine months ended </font>September<font style="font-size: 10pt; font-family: 'Times New Roman';"> 30, 2015, respectively.</font></div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-style: italic; text-align: justify; text-indent: 36pt;">Milestones</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">Milestones, in the form of additional license fees, typically represent nonrefundable payments to be received in conjunction with the achievement of a specific event identified in the license or sublicense agreement, such as completion of specified development activities and/or regulatory submissions and/or approvals. We believe that a milestone represents the culmination of a distinct earnings process when it is not associated with ongoing research, development or other performance on our part. We recognize such milestones as revenue when they become due and collection is reasonably assured. When a milestone does not represent the culmination of a distinct earnings process, we recognize revenue in a manner similar to that of an upfront license fee.</div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">&#160;</div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">The timing and amount of revenue that we recognize from licenses of technology, either from upfront fees or milestones where we are providing continuing services related to product development, are primarily dependent upon our estimates of the development period. We define the development period as the point from which research activities commence up to regulatory approval of either our or our partners&#8217; submission, assuming no further research is necessary. As product candidates move through the development process, it is necessary to revise these estimates to consider changes to the product development cycle, such as changes in the clinical development plan, regulatory requirements, or various other factors, many of which may be outside of our control. Should the U.S. Food and Drug Administration (&#8220;FDA&#8221;) or other regulatory agencies require additional data or information, we would adjust our development period estimates accordingly. The impact on revenue of changes in our estimates and the timing thereof is recognized prospectively over the remaining estimated product development period.<font style="font-size: 10pt; font-family: 'Times New Roman';"> We did not recognize any milestone revenue in the three and nine month periods ended September 30, 2016. 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We consider the following factors when determining the collectability of specific customer accounts: customer credit-worthiness, past transaction history with the customer, current economic industry trends, and changes in customer payment terms.&#160; Our accounts receivable balance is typically due from Endo, our one large specialty pharmaceutical customer.&#160; Endo has historically paid timely and has been a financially stable organization.&#160; Due to the nature of the accounts receivable balance, we believe the risk of doubtful accounts is minimal.&#160; If the financial condition of our customer were to deteriorate, adversely affecting its ability to make payments, additional allowances would be required.&#160; We may provide for estimated uncollectible amounts through a charge to earnings and a credit to a valuation allowance. Balances that remain outstanding after we have used reasonable collection efforts are written off through a charge to the valuation allowance and a credit to accounts receivable.<font style="font-size: 10pt; font-family: 'Times New Roman';">&#160;</font>At <font style="font-size: 10pt; font-family: 'Times New Roman';">September</font> 30, 2016 and December 31, 2015 our accounts receivable balance was $3.8 million and $2.5 million, respectively, and was from one customer, Endo.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">Deferred Revenue</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">Deferred revenue consists of the remaining $7.7 million related to the First Amendment with Endo of mark-up on cost of goods sold revenue for sales by non-affiliated sublicensees, approximately $62,000 related to nonrefundable upfront product license fees for product candidates for which we are providing continuing services related to product development and $100,000 related to a milestone payment withheld by Endo due to a foreign tax withholding which remains uncollected. 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The royalty rates differ from agreement to agreement and, in certain cases, have been redacted with the permission of the SEC.&#160; No assumptions should be made that any disclosed royalty rate payable to a particular third party is the same or similar with respect to any royalty rate payable to any other third parties.&#160; We accrue third-party royalty expenses on net sales reported to us by Endo. Third-party royalty costs are generally expensed in the quarter that Endo provides the written reports and related information to us; that is, generally one quarter following the quarter in which the underlying sales by Endo occurred. For the three and nine month periods ended September 30, 2016, third-party royalty expenses were $0.4 million and $1.2 million , respectively, and for the three and nine month periods ended September 30, 2015, third-party royalty expenses were $0.3 million and $1.0 million, respectively. Our third-party royalty expense under general and administrative expenses may increase if net sales by Endo and its partners for XIAFLEX and XIAPEX increase and potential new indications for CCH are approved.</div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">&#160;</div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">Royalty Buy-Down</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">On March 31, 2012, we entered into an amendment to our existing agreement with Dr. Martin K. Gelbard, dated August 27, 2008, related to our future royalty obligations in connection with Peyronie&#8217;s disease. The amendment enables us to buy down a portion of our future royalty obligations in exchange for an initial cash payment of $1.5 million and five additional cash payments of $600,000, three of which have been paid as of September 30, 2016.&#160; We are currently making the payments to buy down the future royalty obligations, which royalty obligations terminate five years after first commercial sale. The Company amortizes long-term contracts with finite lives in a manner that reflects the pattern in which the economic benefits of the assets are consumed or otherwise used up. Dr. Gelbard&#8217;s agreement is amortized based on an income forecast method by estimating sales of XIAFLEX for Peyronie&#8217;s disease on an annual basis as measured by the proportion of the total estimated sales over the five year period. Related to this agreement, we amortized approximately $247,000 and $740,000 for the three and nine months ended September 30, 2016, respectively, and $221,000 and $420,000 for the three and nine months ended September 30, 2015, respectively. The remaining capitalized balance as of September 30, 2016 was $3.1 million. We perform an evaluation of the recoverability of the carrying value to determine if facts and circumstances indicate that the carrying value of the assets may be impaired and if any adjustment is warranted. Based on our evaluation as of September 30, 2016, no impairment existed and no adjustment was warranted.</div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">&#160;</div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">R&amp;D Expenses</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">R&amp;D<font style="font-size: 10pt; font-family: 'Times New Roman';"> expenses </font>include, but are not limited to, internal costs, such as salaries and benefits, costs of materials, lab expenses, facility costs and overhead. R&amp;D expenses also consist of third party costs, such as medical professional fees, product costs used in clinical trials, consulting fees and costs associated with clinical study arrangements. We may fund R&amp;D at medical research institutions under agreements that are generally cancelable. 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Payments under the contracts depend on factors such as the achievement of certain events, the successful enrollment of patients, the completion of portions of the clinical trial, and other similar conditions. The objective of our accrual policy is to match the recording of expenses in our financial statements to the actual cost of services received and efforts expended. As such, expenses related to each patient enrolled in a clinical trial are recognized ratably beginning upon entry into the trial and over the course of the patient&#8217;s continued participation in the trial. In the event of early termination of a clinical trial, we accrue an amount based on our estimate of the remaining non-cancelable obligations associated with the winding down of the clinical trial. 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When establishing an estimate of the expected term of an option award, we consider the vesting period for the award, our recent historical experience of employee stock option exercises (including forfeitures) and the expected volatility of our common stock.&#160; As required under the accounting rules, we review our estimates at each grant date and, as a result, the valuation assumptions that we use to value employee stock-based awards granted in future periods may change. <font style="font-size: 10pt; font-family: 'Times New Roman';">No stock options were granted</font> during the nine months ended September 30, 2016 and 2015.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">Further, ASC 718 requires that employee stock-based compensation costs be recognized over the requisite service period, or the vesting period, in a manner similar to all other forms of compensation paid to employees. The allocation of employee stock-based compensation costs to each operating expense line are estimated based on specific employee headcount information at each grant date and estimated stock option forfeiture rates and revised, if necessary, in future periods if actual employee headcount information or forfeitures differ materially from those estimates. 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font-family: 'Times New Roman'; font-weight: bold;">7,243,095</div></td><td nowrap="nowrap" valign="bottom" style="vertical-align: bottom; text-align: left; width: 1%; background-color: #ffffff;">&#160;</td></tr></table><div>&#160;</div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">During the nine months ended September 30, 2016 and 2015, the Company received $0.5 million and $2.8 million, respectively, from stock options exercised by option holders.</div><div style="text-align: left;"><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">Aggregate intrinsic value represents the total pre-tax intrinsic value based on the closing price of our common stock of $45.67 on September 30, 2016, which would have been received by the option holders had all option holders exercised their options as of that date. We have approximately $301,000 in unrecognized compensation cost related to stock options outstanding as of September 30, 2016, which we expect to recognize over the next 2.40 years.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">Property and Equipment</div><div style="text-align: justify;"><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">Property and equipment are stated at cost, less accumulated depreciation. Machinery and equipment, furniture and fixtures, and autos are depreciated on a straight-line basis over their estimated useful lives of five to ten years. Leasehold improvements are amortized over the lesser of their estimated useful lives or the remaining life of the lease. As of September 30, 2016 and December 31, 2015, respectively, property and equipment were fully depreciated.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">Comprehensive Income</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">For the three and nine months ended September 30, 2016 and 2015, respectively, we had no components of other comprehensive income other than net income itself.</div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">&#160;</div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">Provision for Income Taxes</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">Deferred tax assets and liabilities are recognized based on the expected future tax consequences, using current tax rates, of temporary differences between the financial statement carrying amounts and the income tax basis of assets and liabilities. A valuation allowance is applied against any net deferred tax asset if, based on the weighted available evidence, it is more likely than not that some or all of the deferred tax assets will not be realized.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;"><font style="font-size: 10pt; font-family: 'Times New Roman';">We use the asset and liability method of accounting for income taxes, as set forth in Accounting Standards Codification. Under this method, deferred income taxes, when required, are provided on the basis of the difference between the financial reporting and income tax basis of assets and liabilities at the statutory rates enacted for future periods. </font>We classify interest associated with income taxes under interest expense and tax penalties under other expense.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">The Company recognizes a tax benefit from an uncertain tax position only if it is more likely than not that the tax position will be sustained on examination by taxing authorities, based on the technical merits of the position. The tax benefit recognized in the consolidated financial statements from such position is measured based on the largest benefit that has a greater than 50% likelihood of being realized upon the ultimate settlement. As of September 30, 2016 and 2015, respectively, the Company has not recorded any unrecognized tax benefits.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: left;">Commitments and Contingencies</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">On November 1, 2016, the Company entered into an agreement with the Landlord to extend the term of the lease to the Headquarters for an additional one year period (the &#8220;Extended Lease Agreement&#8221;). The one year extension will end on November 30, 2017. Pursuant to the Extended Lease Agreement, the base rent is $10,757 per month and the Company may cancel the lease with three months&#8217; prior written notice to the Landlord at any time during the term. The Extended Lease Agreement was filed with the SEC as Exhibit 10.1 to the Company&#8217;s Quarterly Report on Form 10Q on November 9, 2016.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: left;">New Accounting Pronouncements</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify; background-color: #ffffff;"><font style="font-size: 10pt; font-family: 'Times New Roman'; background-color: #ffffff;">The Financial Accounting Standards Board, or FASB</font><font style="font-size: 10pt; font-family: 'Times New Roman';">, issued in May 2014, in August 2015, March 2016 and April 2016,</font> respectively, <font style="font-size: 10pt; font-family: 'Times New Roman';">Accounting Standards Updates No. 2014-09, No. 2015-14, No. 2016-08, and No. 2016-10 (the &#8220;ASUs&#8221;). These ASUs were issued in connection with revenue from contracts with customers. The new standard provides a five-step approach to be applied to all contracts with customers and also requires expanded disclosures about revenue recognition. In August 2015, the FASB deferred the effective date of the guidance to reporting periods, including interim periods, beginning after December 15, 2017, and will be applied retrospectively. Early adoption is not permitted. </font><font style="font-size: 10pt; font-family: 'Times New Roman'; background-color: #ffffff;">We are currently evaluating the timing, method of adoption and the expected impact that the standard could have on our consolidated financial statements and related disclosures. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.</font></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify; background-color: #ffffff;">&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160; <br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">In January 2016, the FASB issued new guidance on recognition and measurement of financial assets and financial liabilities. The new guidance will impact the accounting for equity investments, financial liabilities under the fair value option, and the presentation and disclosure requirements for financial instruments. All equity investments in unconsolidated entities (other than those accounted for under the equity method of accounting) will generally be measured at fair value with changes in fair value recognized through earnings. There will no longer be an available-for-sale classification (changes in fair value reported in other comprehensive income (loss) for equity securities with readily determinable fair values. In addition, the FASB clarified the need for a valuation allowance on deferred tax assets resulting from unrealized losses on available-for-sale debt securities. In general, the new guidance will require modified retrospective application to all outstanding instruments, with a cumulative effect adjustment recorded to opening retained earnings. This guidance will be effective for us on January 1, 2018. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;"><font style="font-size: 10pt; font-family: 'Times New Roman'; background-color: #ffffff;">In February 2016, FASB issued Accounting Standards Update (ASU) No. 2016-02, </font><font style="font-size: 10pt; font-family: 'Times New Roman'; font-style: italic; background-color: #ffffff;">Leases (Topic 842). </font><font style="font-size: 10pt; font-family: 'Times New Roman'; background-color: #ffffff;">Under the new guidance, lessees will be required to recognize the following for all leases (with the exception of short-term leases) at the lease commencement date: a lease liability, which is a lessee&#8217;s obligation to make lease payments arising from a lease, measured on a discounted basis; and a right-of-use asset, which is an asset that represents the lessee&#8217;s right to use, or control the use of, a specified asset for the lease term. Under the new guidance, lessor accounting is largely unchanged. Certain targeted improvements were made to align, where necessary, lessor accounting with the lessee accounting model and Topic 606, </font><font style="font-size: 10pt; font-family: 'Times New Roman'; font-style: italic; background-color: #ffffff;">Revenue from Contracts with Customers</font><font style="font-size: 10pt; font-family: 'Times New Roman'; background-color: #ffffff;">. The new lease guidance simplified the accounting for sale and leaseback transactions primarily because lessees must recognize lease assets and lease liabilities. Lessees will no longer be provided with a source of off-balance sheet financing. Public business entities should apply the amendments in ASU 2016-02 for fiscal years beginning after December 15, 2018, including interim periods within those fiscal years (i.e., January 1, 2019, for a calendar year entity). Early application is permitted.&#160; Lessees (for capital and operating leases) and lessors (for sales-type, direct financing, and operating leases) must apply a modified retrospective transition approach for leases existing at, or entered into after, the beginning of the earliest comparative period presented in the financial statements. The modified retrospective approach would not require any transition accounting for leases that expired before the earliest comparative period presented. 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We are currently evaluating this guidance and the impact it will have on the consolidated financial statements and related disclosures.</div><div><br /></div></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">In May 2016, FASB issued ASU No. 2016-12, Revenue from Contracts with Customers (Topic 606): Narrow-Scope Improvements and Practical Expedients, which is intended to not change the core principle of the guidance in Topic 606, but rather affect only the narrow aspects of Topic 606 by reducing the potential for diversity in practice at initial application and by reducing the cost and complexity of applying Topic 606 both at transition and on an ongoing basis. 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The one year extension will end on November 30, 2017. Pursuant to the Extended Lease Agreement, the base rent is $10,757 per month and the Company may cancel the lease with three months&#8217; prior written notice to the Landlord at any time during the term. The Extended Lease Agreement was filed with the SEC as Exhibit 10.1 to the Company&#8217;s Quarterly Report on Form 10Q on November 9, 2016.</div></div> 0 279333 <div style="font-family: 'Times New Roman'; font-size: 10pt;"><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">Receivables and Doubtful Accounts</div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">&#160;</div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">Trade accounts receivable are stated at the amount the Company expects to collect. 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The Company makes certain assumptions and estimates for its deferred tax assets and deferred royalty buy-down. For further details see notes &#8220;Provision for Income Taxes&#8221; and &#8220;Third-Party Royalties and Royalty Buy-Down.&#8221; Actual results may differ from those estimates.</div></div> 7259338 7277780 7280375 7316287 6892637 7031068 7062543 6797506 <div style="font-family: 'Times New Roman'; font-size: 10pt;"><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">Royalty Buy-Down</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">On March 31, 2012, we entered into an amendment to our existing agreement with Dr. Martin K. Gelbard, dated August 27, 2008, related to our future royalty obligations in connection with Peyronie&#8217;s disease. The amendment enables us to buy down a portion of our future royalty obligations in exchange for an initial cash payment of $1.5 million and five additional cash payments of $600,000, three of which have been paid as of September 30, 2016.&#160; We are currently making the payments to buy down the future royalty obligations, which royalty obligations terminate five years after first commercial sale. The Company amortizes long-term contracts with finite lives in a manner that reflects the pattern in which the economic benefits of the assets are consumed or otherwise used up. Dr. Gelbard&#8217;s agreement is amortized based on an income forecast method by estimating sales of XIAFLEX for Peyronie&#8217;s disease on an annual basis as measured by the proportion of the total estimated sales over the five year period. Related to this agreement, we amortized approximately $247,000 and $740,000 for the three and nine months ended September 30, 2016, respectively, and $221,000 and $420,000 for the three and nine months ended September 30, 2015, respectively. The remaining capitalized balance as of September 30, 2016 was $3.1 million. We perform an evaluation of the recoverability of the carrying value to determine if facts and circumstances indicate that the carrying value of the assets may be impaired and if any adjustment is warranted. Based on our evaluation as of September 30, 2016, no impairment existed and no adjustment was warranted.</div></div> <div style="font-family: 'Times New Roman'; font-size: 10pt;"><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">Third-Party Royalties</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">We have entered into licensing and royalty agreements with third parties and agreed to pay certain royalties on net sales of products for specific indications. The royalty rates differ from agreement to agreement and, in certain cases, have been redacted with the permission of the SEC.&#160; No assumptions should be made that any disclosed royalty rate payable to a particular third party is the same or similar with respect to any royalty rate payable to any other third parties.&#160; We accrue third-party royalty expenses on net sales reported to us by Endo. Third-party royalty costs are generally expensed in the quarter that Endo provides the written reports and related information to us; that is, generally one quarter following the quarter in which the underlying sales by Endo occurred. For the three and nine month periods ended September 30, 2016, third-party royalty expenses were $0.4 million and $1.2 million , respectively, and for the three and nine month periods ended September 30, 2015, third-party royalty expenses were $0.3 million and $1.0 million, respectively. Our third-party royalty expense under general and administrative expenses may increase if net sales by Endo and its partners for XIAFLEX and XIAPEX increase and potential new indications for CCH are approved.</div></div> <div style="font-family: 'Times New Roman'; font-size: 10pt;"><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: left;">Clinical Trial Expenses</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">Our cost accruals for clinical trials are based on estimates of the services received and efforts expended pursuant to contracts with various clinical trial centers and clinical research organizations. In the normal course of business we contract with third parties to perform various clinical trial activities in the ongoing development of potential drugs. The financial terms of these agreements are subject to negotiation and vary from contract to contract and may result in uneven payment flows. Payments under the contracts depend on factors such as the achievement of certain events, the successful enrollment of patients, the completion of portions of the clinical trial, and other similar conditions. The objective of our accrual policy is to match the recording of expenses in our financial statements to the actual cost of services received and efforts expended. As such, expenses related to each patient enrolled in a clinical trial are recognized ratably beginning upon entry into the trial and over the course of the patient&#8217;s continued participation in the trial. In the event of early termination of a clinical trial, we accrue an amount based on our estimate of the remaining non-cancelable obligations associated with the winding down of the clinical trial. Our estimates and assumptions could differ significantly from the amounts that may actually be incurred.</div></div> <div style="font-family: 'Times New Roman'; font-size: 10pt;"><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">Reimbursable Third-Party Development Costs</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">We accrued patent expenses for that are reimbursable by us under the License Agreement.&#160; We capitalize certain patent costs related to estimated third-party development costs that are reimbursable under the License Agreement. As of September<font style="font-size: 10pt; font-family: 'Times New Roman';"> 30, 2016 and December 31, 2015,</font> our net reimbursable third party patent expense accrual was approximately $25,000 and $20,000, respectively.</div></div> <div style="font-family: 'Times New Roman'; font-size: 10pt;"><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">Treasury Stock</div><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; text-align: justify;">&#160;</div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">The Company accounts for treasury stock under the cost method and includes treasury stock as a component of stockholders&#8217; equity. For the nine months ended <font style="font-size: 10pt; font-family: 'Times New Roman';">September</font> 30, 2016, we repurchased 24,020 shares at an average price of $37.39 as compared to the repurchase of 27,433 shares at an average price of $43.07 in the corresponding 2015 period.</div></div> <div style="font-family: 'Times New Roman'; font-size: 10pt;"><div style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold; font-style: italic; text-align: justify; text-indent: 36pt;">Royalty / Mark-Up on Cost of Goods Sold</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">For those arrangements for which royalty and mark-up on cost of goods sold information becomes available and collectability is reasonably assured, we recognize revenue during the applicable period in which it is earned. For interim quarterly and year-end reporting purposes, when collectability is reasonably assured, but a reasonable estimate of royalty and mark-up on cost of goods sold cannot be made, the royalty and mark-up on cost of goods sold are generally recognized in the quarter that the applicable licensee provides the written report and related information to us.</div><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;">Under the License Agreement, we do not participate in the selling, marketing or manufacturing of products for which we receive royalties and a mark-up on the cost of goods sold. The royalty and mark-up on cost of goods sold will generally be recognized in the quarter that Endo provides the written reports and related information to us; that is, royalty and mark-up on cost of goods sold are generally recognized one quarter following the quarter in which the underlying sales by Endo occurred.<font style="font-size: 10pt; font-family: 'Times New Roman'; font-weight: bold;">&#160;</font>The royalties payable by Endo to us are subject to set-off for certain patent costs.</div><div style="background-color: #ffffff;"><div><br /></div><div style="font-size: 10pt; font-family: 'Times New Roman'; text-align: justify;"><font style="font-size: 10pt; font-family: 'Times New Roman';">Pursuant to the First Amendment with Endo, in exchange for a $8.25 million lump sum payment, we will not receive future additional mark-up on cost of goods sold for sales by non-affiliated sublicensees of Endo outside of the U.S.; provided, however, that Endo will still be required to pay a mark-up on cost of goods sold for sales made in the &#8220;Endo Territory,&#8221; which includes sales made in the U.S. and sales made in any other country where Endo sells the product directly or through affiliated sublicensees. 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Attributable to Parent SUBSEQUENT EVENTS [Abstract] Subsequent Event [Member] SUBSEQUENT EVENTS Subsequent Events [Text Block] Subsequent Event Type [Axis] Subsequent Event [Line Items] Subsequent Event [Table] Subsequent Event Type [Domain] Supplemental disclosures of cash flow information: Income taxes payable Receivables and Doubtful Accounts Average price of share (in dollars per share) Treasury stock, shares (in shares) Treasury stock purchased (in shares) Treasury Stock, Shares, Acquired Treasury stock, 395,608 and 371,588 shares at cost as of September 30, 2016 and December 31, 2015, respectively Treasury Stock, Value Treasury Stock [Abstract] Unrealized gains (losses) on investments Interest and penalties Unrecognized tax benefits Uncertain tax positions Critical Accounting Policies, Estimates and Assumptions Use of Estimates, Policy [Policy Text Block] Shares used in computation of diluted net income per share (in shares) Number of common equivalent shares included for the calculation of diluted net income [Abstract] Shares used in computation of basic net income per share (in shares) Document and Entity Information [Abstract] Disclosure of accounting policy for royalty buy down. Royalty Buy Down [Policy Text Block] Royalty Buy-Down Disclosure of accounting policy for third party licensing and royalties agreements. Third Party Royalties [Policy Text Block] Third-Party Royalties Disclosure of accounting policy for clinical trial expenses. Clinical Trial Expenses [Policy Text Block] Clinical Trial Expenses Disclosure of accounting policy for reimbursable third party development costs. Reimbursable Third Party Development Costs [Policy Text Block] Reimbursable Third-Party Development Costs Disclosure of accounting policy for treasury stock. Treasury Stock [Policy Text Block] Treasury Stock Disclosure of accounting policy refers to royalty on cost of good sold. Royalty / Mark-Up on Cost of Goods Sold [Policy Text Block] Royalty / Mark-Up on Cost of Goods Sold Aggregate intrinsic value of forfeitures or expirations option during the reporting period as calculated by applying the disclosed option pricing methodology. Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures or Expirations in Period, Intrinsic Value Aggregate intrinsic value, forfeitures or expirations Carrying value as of the balance sheet date of obligations incurred through that date and payable for patents. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued patent costs Accrued patent costs Royalty Mark up on Cost of Goods Sold Earn Out Revenue [Abstract] Royalty / Mark-Up on Cost of Goods Sold [Abstract] Reimbursable Third Party Development Costs [Abstract] Reimbursable Third Party Development Costs [Abstract] Amount of deferred or unearned revenue that was received for foreign tax withholding as of the Balance Sheet date. Deferred Revenue Recognized From Foreign Tax Withholding Deferred revenue from foreign tax withholding Revenue earned during the period relating to consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Licensing fees are generally, but not always, fixed as to amount and not dependent upon the revenue generated by the licensing party. An entity may receive licensing fees for licenses that also generate royalty payments to the entity. Nonrefundable Upfront Product License Fees Nonrefundable upfront product license fees Refers to the term of notice period for cancellation of lease agreement in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Notice Period To Cancel Lease Agreements Notice period to cancel lease agreements The duration period related to the amortization of deferred cost. Deferred Costs Amortization Period Deferred costs amortization period The number of additional cash payments for royalty buy-down. Number of additional cash payments for royalty buy down The cash outflow from initial payment related to the purchase of royalty interests. Payment for royalty buy down Payment for royalty buy down Number of cash payments made to reduce royalty obligation. Number of cash payments made for royalty obligation Royalty Buy Down [Abstract] The amount of monthly rent of leased premises during the period. Monthly rent of leased premises Monthly base rent Third Party Royalties [Abstract] Aggregate intrinsic value of grant-date options granted during the reporting period as calculated by applying the disclosed option pricing methodology. Share-based Compensation Arrangement by Share-based Payment Award, Options, Grant in Period, Intrinsic Value Aggregate intrinsic value, grants Represents the extended term of operating lease. Extended Term of Operating Lease Additional lease term extension period Weighted average remaining contractual term in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Sharebased Compensation Arrangement By Sharebased Payment Award Weighted Average Remaining Contractual Roll Forward [Roll Forward] Weighted Average Remaining Contractual Term [Roll Forward] Commitments and Contingencies [Abstract] Commitments and Contingencies [Abstract] Revenue Recognition, Milestone Method [Abstract] Milestones Revenue [Abstract] Number of stock based compensation plans in effect for employees and directors. Number of stock based compensation plans in effect Carrying value as of the balance sheet date of obligations incurred (and for which invoices have typically been received) and payable to vendors for goods and services received that are used in an entity's business and pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Trade accounts payable and accrued expenses Cash paid during the year for [Abstract] Cash paid during the period for: Sum of the carrying values as of the balance sheet date of obligations incurred through that date and due within one year (or the operating cycle, if longer), including liabilities incurred (and for which invoices have typically been received) and payable to vendors for goods and services received, taxes, interest, rent and utilities, accrued salaries and bonuses, payroll taxes and fringe benefits. Accounts Payables and Accrued Liabilities, Current Accounts payable and accrued expenses The regular opt in fee receivable for each indication during the period. Regular Opt in Fee Receivable for Each Indication Regular opt-in fee receivable for each indication The opt in fee receivable for each indication during the period. Opt in fee receivable for each indication Opt-in fee receivable for each indication Represents one of the major pharmaceutical customer of the entity from which a large part of revenue is generated. Endo [Member] EX-101.PRE 10 bstc-20160930_pre.xml XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE XML 11 R1.htm IDEA: XBRL DOCUMENT v3.5.0.2
Document and Entity Information - shares
9 Months Ended
Sep. 30, 2016
Nov. 08, 2016
Document and Entity Information [Abstract]    
Entity Registrant Name BIOSPECIFICS TECHNOLOGIES CORP  
Entity Central Index Key 0000875622  
Current Fiscal Year End Date --12-31  
Entity Well-known Seasoned Issuer No  
Entity Voluntary Filers No  
Entity Current Reporting Status Yes  
Entity Filer Category Accelerated Filer  
Entity Common Stock, Shares Outstanding   7,147,159
Document Fiscal Year Focus 2016  
Document Fiscal Period Focus Q3  
Document Type 10-Q  
Amendment Flag false  
Document Period End Date Sep. 30, 2016  
XML 12 R2.htm IDEA: XBRL DOCUMENT v3.5.0.2
Condensed Consolidated Balance Sheets (unaudited) - USD ($)
Sep. 30, 2016
Dec. 31, 2015
Current assets:    
Cash and cash equivalents $ 4,747,745 $ 5,137,875
Short term investments 45,075,570 28,347,542
Accounts receivable 3,846,752 2,547,920
Income tax receivable 0 916,843
Deferred royalty buy-down 1,215,620 1,017,981
Prepaid expenses and other current assets 554,401 383,810
Total current assets 55,440,088 38,351,971
Long-term investments 1,443,099 3,596,541
Deferred royalty buy-down - long term, net 1,913,697 2,851,423
Deferred tax assets, net 3,370,836 622,972
Patent costs, net 268,928 275,206
Total assets 62,436,648 45,698,113
Current liabilities:    
Accounts payable and accrued expenses 991,867 611,009
Income taxes payable 279,333 0
Deferred revenue 1,223,479 149,378
Accrued liabilities of discontinued operations 78,138 78,138
Total current liabilities 2,572,817 838,525
Long-term deferred revenue 6,642,441 49,379
Stockholders' equity:    
Series A Preferred stock, $.50 par value, 700,000 shares authorized; none outstanding 0 0
Common stock, $.001 par value; 10,000,000 shares authorized; 7,545,167 and 7,290,167 shares issued, 7,149,559 and 6,918,579 shares outstanding as of September 30, 2016 and December 31, 2015, respectively 7,545 7,290
Additional paid-in capital 32,650,938 31,797,418
Retained earnings 27,694,041 19,238,610
Treasury stock, 395,608 and 371,588 shares at cost as of September 30, 2016 and December 31, 2015, respectively (7,131,134) (6,233,109)
Total stockholders' equity 53,221,390 44,810,209
Total liabilities and stockholders' equity $ 62,436,648 $ 45,698,113
XML 13 R3.htm IDEA: XBRL DOCUMENT v3.5.0.2
Condensed Consolidated Balance Sheets (unaudited) (Parenthetical) - $ / shares
Sep. 30, 2016
Dec. 31, 2015
Stockholders' equity:    
Series A Preferred stock, par value (in dollars per share) $ 0.50 $ 0.50
Series A Preferred stock, authorized (in shares) 700,000 700,000
Series A Preferred stock, outstanding (in shares) 0 0
Common stock, par value (in dollars per share) $ 0.001 $ 0.001
Common stock, authorized (in shares) 10,000,000 10,000,000
Common stock, issued (in shares) 7,545,167 7,290,167
Common stock, outstanding (in shares) 7,149,559 6,918,579
Treasury stock, shares (in shares) 395,608 371,588
XML 14 R4.htm IDEA: XBRL DOCUMENT v3.5.0.2
Condensed Consolidated Income Statements (unaudited) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Revenues:        
Royalties $ 6,119,815 $ 5,277,494 $ 18,843,273 $ 15,574,234
Licensing revenues 762,345 1,012,345 787,034 1,037,034
Total Revenues 6,882,160 6,289,839 19,630,307 16,611,268
Costs and expenses:        
Research and development 312,907 258,837 1,005,884 755,038
General and administrative 1,843,368 1,709,044 5,909,785 5,307,431
Total Cost and Expenses 2,156,275 1,967,881 6,915,669 6,062,469
Operating income 4,725,885 4,321,958 12,714,638 10,548,799
Other income:        
Interest income 80,674 26,744 200,704 58,946
Other income 6,254 1,477 37,448 6,110
Total other income 86,928 28,221 238,152 65,056
Income before income tax expense 4,812,813 4,350,179 12,952,790 10,613,855
Provision for income tax expense (1,759,220) (1,479,200) (4,497,359) (3,654,772)
Net income $ 3,053,593 $ 2,870,979 $ 8,455,431 $ 6,959,083
Basic net income per share (in dollars per share) $ 0.43 $ 0.42 $ 1.20 $ 1.02
Diluted net income per share (in dollars per share) $ 0.42 $ 0.39 $ 1.16 $ 0.96
Shares used in computation of basic net income per share (in shares) 7,062,543 6,892,637 7,031,068 6,797,506
Shares used in computation of diluted net income per share (in shares) 7,280,375 7,316,287 7,277,780 7,259,338
XML 15 R5.htm IDEA: XBRL DOCUMENT v3.5.0.2
Condensed Consolidated Statements of Cash Flows (unaudited) - USD ($)
9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Cash flows from operating activities:    
Net income $ 8,455,431 $ 6,959,083
Adjustments to reconcile net income to net cash provided by operating activities:    
Amortization 1,215,814 647,071
Stock-based compensation expense 100,428 72,305
Deferred tax expense (2,747,864) 441,211
Changes in operating assets and liabilities:    
Accounts receivable (1,298,832) (1,273,079)
Income tax receivable 916,843 (521,121)
Prepaid expenses and other current assets (170,591) (136,152)
Patent costs (23,341) (24,204)
Accounts payable and accrued expenses 380,858 107,372
Income taxes payable 279,333 0
Deferred revenue 7,667,163 (37,034)
Net cash provided by operating activities 14,775,242 6,235,452
Cash flows from investing activities:    
Maturity of marketable investments 32,548,040 11,043,544
Purchases of marketable investments (47,568,734) (24,422,334)
Net cash used in investing activities (15,020,694) (13,378,790)
Cash flows from financing activities:    
Proceeds from stock option exercises 529,300 2,813,984
Payments for repurchase of common stock (898,025) (1,182,068)
Excess tax benefits from share-based payment arrangements 224,047 3,188,682
Net cash (used in) provided by financing activities (144,678) 4,820,598
Decrease in cash and cash equivalents (390,130) (2,322,740)
Cash and cash equivalents at beginning of year 5,137,875 9,810,816
Cash and cash equivalents at end of period 4,747,745 7,488,076
Cash paid during the period for:    
Interest 0 0
Taxes $ 5,825,000 $ 546,000
XML 16 R6.htm IDEA: XBRL DOCUMENT v3.5.0.2
ORGANIZATION AND DESCRIPTION OF BUSINESS
9 Months Ended
Sep. 30, 2016
ORGANIZATION AND DESCRIPTION OF BUSINESS [Abstract]  
ORGANIZATION AND DESCRIPTION OF BUSINESS
1.
ORGANIZATION AND DESCRIPTION OF BUSINESS

We are a biopharmaceutical company involved in the development of an injectable collagenase clostridium histolyticum, or CCH, for multiple indications. We currently have a development and license agreement with Endo Global Ventures International plc (together with Endo International plc, an affiliate of Endo Global Ventures, “Endo”) for injectable collagenase for marketed indications and indications in development. Endo assumed this agreement when Endo acquired Auxilium Pharmaceuticals, Inc. (“Auxilium”) on January 29, 2015 (the “Acquisition”).  CCH is marketed as XIAFLEX® (or XIAPEX® in Europe).

On February 5, 2016, we announced that we had entered into with Endo the First Amendment (the “First Amendment”) to the Second Amended and Restated Development and Licensing Agreement (the “Auxilium Agreement”), by and between us and Auxilium, now a wholly-owned subsidiary of Endo, to amend certain provisions of the Auxilium Agreement (as amended by the First Amendment, the “License Agreement”). The effective date of the First Amendment was January 1, 2016. Pursuant to the First Amendment, we and Endo mutually agreed that in exchange for a $8.25 million lump sum payment, we will not receive future additional mark-up on cost of goods sold for sales by non-affiliated sublicensees of Endo outside of the U.S.; provided, however, that Endo will still be required to pay a mark-up on cost of goods sold for sales made in the "Endo Territory," which includes sales made in the U.S. and sales made in any other country where Endo sells the product directly or through affiliated sublicensees. We received this $8.25 million lump sum payment in February 2016 and began recognizing this income over time based on sales by non-affiliated sublicensees of Endo outside of the U.S. according to our revenue recognition policy in the second quarter of 2016.

Additionally, we agreed that Endo may opt-in early to indications, prior to our submission of a clinical trial report, with our consent, such consent not to be unreasonably withheld. For early opt-ins, Endo will be required to make an opt-in payment of $0.5 million on a per indication basis. For regular opt-ins, following our submission of a clinical trial report, Endo will be required to make an opt-in payment of $0.75 million on a per indication basis.

The two marketed indications involving our injectable collagenase are Dupuytren’s contracture and Peyronie’s disease. Prior to the Acquisition, Auxilium had, and after the Acquisition, Endo has, opted-in to the following indications: frozen shoulder, cellulite, canine lipoma, lateral hip fat, plantar fibromatosis and human lipoma. We manage the development of CCH for uterine fibroids and initiate the development of CCH in new potential indications, not licensed by Endo.

Endo is currently selling XIAFLEX in the U.S. for the treatment of Dupuytren’s contracture and Peyronie’s disease and has an agreement with Swedish Orphan Biovitrum AB (“Sobi”), pursuant to which Sobi has marketing rights for XIAPEX for Dupuytren’s contracture and Peyronie’s disease in Europe and certain Eurasian countries. Sobi is currently selling XIAPEX in Europe for the treatment of Dupuytren’s contracture and Peyronie’s disease. In addition, Endo has an agreement with Asahi Kasei Pharma Corporation (“Asahi”) pursuant to which Asahi has the right to commercialize XIAFLEX for the treatment of Dupuytren’s contracture and Peyronie’s disease in Japan. Asahi has received regulatory approval and is currently selling XIAFLEX for the treatment of Dupuytren’s contracture in Japan.

 
XML 17 R7.htm IDEA: XBRL DOCUMENT v3.5.0.2
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
9 Months Ended
Sep. 30, 2016
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES [Abstract]  
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
2.
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

Basis of Presentation

The accompanying condensed consolidated financial statements are unaudited, but include all adjustments (consisting only of normal, recurring adjustments) which we consider necessary for a fair presentation of our financial position at such dates and the operating results and cash flows for those periods. Although we believe that the disclosures in our financial statements are adequate to make the information presented not misleading, certain information normally included in financial statements prepared in accordance with U.S. generally accepted accounting principles (“U.S. GAAP”) has been condensed or omitted pursuant to the rules and regulations of the Securities and Exchange Commission (the “SEC”) for quarterly reporting.
 
The information included in this Report should be read in conjunction with the risk factors discussed in “Part I, Item 1A. Risk Factors” in our Quarterly Reports on Form 10Q for the periods ended March 31, 2016 and June 30, 2016 filed with the SEC on May 10, 2016 and August 9, 2016, respectively and our Annual Report on Form 10-K for the period ended December 31, 2015 filed with the SEC on March 14, 2016.

Principles of Consolidation

The condensed consolidated financial statements include the accounts of the Company and its subsidiary, Advance Biofactures Corp. (“ABC-NY”). All intercompany balances and transactions have been eliminated.

Critical Accounting Policies, Estimates and Assumptions

The preparation of condensed consolidated financial statements in conformity with U.S. GAAP requires the use of management’s estimates and assumptions that affect the amounts reported in the condensed consolidated financial statements and accompanying notes. The Company makes certain assumptions and estimates for its deferred tax assets and deferred royalty buy-down. For further details see notes “Provision for Income Taxes” and “Third-Party Royalties and Royalty Buy-Down.” Actual results may differ from those estimates.

Cash, Cash Equivalents and Investments

Cash equivalents include only securities having a maturity of three months or less at the time of purchase. Investments are stated on an amortized cost basis. The Company limits its credit risk associated with cash, cash equivalents and investments by placing its investments with banks it believes are highly creditworthy and with highly rated money market funds, certificates of deposit and municipal bonds. All investments are classified as held to maturity. As of September 30, 2016 and December 31, 2015, the aggregate fair value of these investments was $46.5 million and $31.9 million, respectively.

Fair Value Measurements

Management believes that the carrying amounts of the Company’s financial instruments, including cash, cash equivalents, held to maturity investments, accounts receivable, accounts payable and accrued expenses approximate fair value due to the short-term nature of those instruments. As of September 30, 2016 and December 31, 2015, there were no recorded unrealized gains or losses on our investments as they are held to maturity. As of September 30, 2016, amortized cost basis of the investments approximate their fair value. At September 30, 2016 and December 31, 2015, the amortized premium included in interest income was $446,000 and $316,000, respectively.

The following table presents the Company’s schedule of maturities at September 30, 2016 and December 31, 2015:

  
Maturities as of
September 30, 2016
  
Maturities as of
December 31, 2015
 
       
  
1 Year or Less
  
Greater than
1 Year
  
1 Year or
Less
  
Greater than 1
Year
 
                 
Municipal bonds
 
$
6,917,696
  
$
-
  
$
6,461,216
  
$
155,826
 
                 
Corporate Bonds
  
31,218,996
   
1,194,049
   
9,882,285
   
1,597,715
 
                 
Certificates of deposit
  
6,938,878
   
249,050
   
12,004,041
   
1,843,000
 
Total
 
$
45,075,570
  
$
1,443,099
  
$
28,347,542
  
$
3,596,541
 
 
The authoritative literature for fair value measurements established a three-tier fair value hierarchy, which prioritizes the inputs in measuring fair value. These tiers are as follows: Level 1, defined as observable inputs such as quoted market prices in active markets; Level 2, defined as inputs other than the quoted prices in active markets that are either directly or indirectly observable; and Level 3, defined as significant unobservable inputs (entity developed assumptions) in which little or no market data exists.

As of September 30, 2016, the Company held certain investments that are required to be measured at fair value on a recurring basis. The following tables present the Company’s fair value hierarchy for these financial assets as of September 30, 2016 and December 31, 2015:

September 30, 2016
Type of Instrument
 
Fair Value
  
Level 1
  
Level 2
  
Level 3
 
                  
Cash equivalents
Institutional Money Market
 
$
1,894,904
  
$
1,894,904
   
-
   
-
 
                  
Investments
Municipal Bonds
  
6,917,696
   
-
  
$
6,917,696
   
-
 
                  
Investments
Corporate Bonds
  
32,413,045
   
-
   
32,413,045
   
-
 
                  
Investments
Certificates of Deposit
  
7,187,928
   
7,187,928
   
-
   
-
 
              
December 31, 2015
Type of Instrument
 
Fair Value
  
Level 1
  
Level 2
  
Level 3
 
                  
Cash equivalents
Institutional Money Market
 
$
715,784
  
$
715,784
   
-
   
-
 
                  
Investments
Municipal Bonds
  
6,617,042
   
-
  
$
6,617,042
   
-
 
                  
Investments
Corporate Bonds
  
11,480,000
   
-
   
11,480,000
   
-
 
                  
Investments
Certificates of Deposit
  
13,847,041
   
13,847,041
   
-
   
-
 
 
Concentration of Credit Risk and Major Customers

The Company maintains bank account balances, which, at times, may exceed insured limits. The Company has not experienced any losses with these accounts and believes that it is not exposed to any significant credit risk on cash.

The Company maintains its investment in FDIC insured certificates of deposits with several banks, pre-refunded municipal bonds, municipal bonds and corporate bonds.

The Company is currently dependent on one customer, Endo, who generates almost all its revenues. For the three and nine months ended September 30, 2016, licensing, sublicensing, milestones and royalty revenues under the License Agreement with Endo were approximately $6.9 million and $19.6 million, respectively, and for the three and nine months ended September 30, 2015, the licensing, sublicensing, milestones and royalty revenues under the License Agreement with Endo were approximately $6.3 million and $16.6 million, respectively.

At September 30, 2016 and December 31, 2015, our accounts receivable balances were $3.8 million and $2.5 million, respectively.

Revenue Recognition
 
We currently recognize revenues resulting from the licensing and sublicensing of the use of our technology and from services we sometimes perform in connection with the licensed technology under the guidance of Accounting Standards Codification 605, Revenue Recognition (“ASC 605”).

If we determine that separate elements exist in a revenue arrangement under ASC 605, we recognize revenue for delivered elements only when the fair values of undelivered elements are known, when the associated earnings process is complete, when payment is reasonably assured and, to the extent the milestone amount relates to our performance obligation, when our customer confirms that we have met the requirements under the terms of the agreement.
 
Revenues, and their respective treatment for financial reporting purposes, are as follows:
 
Royalty / Mark-Up on Cost of Goods Sold

For those arrangements for which royalty and mark-up on cost of goods sold information becomes available and collectability is reasonably assured, we recognize revenue during the applicable period in which it is earned. For interim quarterly and year-end reporting purposes, when collectability is reasonably assured, but a reasonable estimate of royalty and mark-up on cost of goods sold cannot be made, the royalty and mark-up on cost of goods sold are generally recognized in the quarter that the applicable licensee provides the written report and related information to us.

Under the License Agreement, we do not participate in the selling, marketing or manufacturing of products for which we receive royalties and a mark-up on the cost of goods sold. The royalty and mark-up on cost of goods sold will generally be recognized in the quarter that Endo provides the written reports and related information to us; that is, royalty and mark-up on cost of goods sold are generally recognized one quarter following the quarter in which the underlying sales by Endo occurred. The royalties payable by Endo to us are subject to set-off for certain patent costs.

Pursuant to the First Amendment with Endo, in exchange for a $8.25 million lump sum payment, we will not receive future additional mark-up on cost of goods sold for sales by non-affiliated sublicensees of Endo outside of the U.S.; provided, however, that Endo will still be required to pay a mark-up on cost of goods sold for sales made in the “Endo Territory,” which includes sales made in the U.S. and sales made in any other country where Endo sells the product directly or through affiliated sublicensees. We received this $8.25 million lump sum payment in February 2016. We classified this payment as deferred revenue in our balance sheet and began recognizing this income over time in the second quarter of 2016 based on sales by non-affiliated sublicensees of Endo outside of the U.S. according to our revenue recognition policy. We recognized approximately $274,000 and $546,000 for the three and nine months ended September 30, 2016, and zero in each of the 2015 corresponding periods.

Licensing Revenue

We include revenue recognized from upfront licensing, sublicensing and milestone payments in “License Revenues” in our condensed consolidated statements of income in this Quarterly Report on Form 10-Q.

Upfront License and Sublicensing Fees

We generally recognize revenue from upfront licensing and sublicensing fees when the license or sublicense agreement is signed, we have completed the earnings process and we have no ongoing performance obligation with respect to the arrangement. We recognized licensing fees related to the exercise of an opt-in right by Endo for the human lipoma indication of $750,000 for the three and nine months ended September 30, 2016 as compared to zero in each of the 2015 periods. Nonrefundable upfront technology license fees for product candidates for which we are providing continuing services related to product development are deferred and recognized as revenue over the development period. We recognized deferred revenue of $12,345 and $37,034 for the three and nine months ended September 30, 2016, respectively, and $12,345 and $37,034 for the three and nine months ended September 30, 2015, respectively.

Milestones

Milestones, in the form of additional license fees, typically represent nonrefundable payments to be received in conjunction with the achievement of a specific event identified in the license or sublicense agreement, such as completion of specified development activities and/or regulatory submissions and/or approvals. We believe that a milestone represents the culmination of a distinct earnings process when it is not associated with ongoing research, development or other performance on our part. We recognize such milestones as revenue when they become due and collection is reasonably assured. When a milestone does not represent the culmination of a distinct earnings process, we recognize revenue in a manner similar to that of an upfront license fee.
 
The timing and amount of revenue that we recognize from licenses of technology, either from upfront fees or milestones where we are providing continuing services related to product development, are primarily dependent upon our estimates of the development period. We define the development period as the point from which research activities commence up to regulatory approval of either our or our partners’ submission, assuming no further research is necessary. As product candidates move through the development process, it is necessary to revise these estimates to consider changes to the product development cycle, such as changes in the clinical development plan, regulatory requirements, or various other factors, many of which may be outside of our control. Should the U.S. Food and Drug Administration (“FDA”) or other regulatory agencies require additional data or information, we would adjust our development period estimates accordingly. The impact on revenue of changes in our estimates and the timing thereof is recognized prospectively over the remaining estimated product development period. We did not recognize any milestone revenue in the three and nine month periods ended September 30, 2016. Milestone revenue recognized for the three and nine months ended September 30, 2015 was $1.0 million in each period.  The $1.0 million milestone revenue recognized in the 2015 periods related to the first commercial sale of XIAFLEX by Asahi for the treatment of Dupuytren's contracture in Japan.

Treasury Stock
 
The Company accounts for treasury stock under the cost method and includes treasury stock as a component of stockholders’ equity. For the nine months ended September 30, 2016, we repurchased 24,020 shares at an average price of $37.39 as compared to the repurchase of 27,433 shares at an average price of $43.07 in the corresponding 2015 period.
 
Receivables and Doubtful Accounts
 
Trade accounts receivable are stated at the amount the Company expects to collect. We may maintain allowances for doubtful accounts for estimated losses resulting from the inability of our customers to make required payments. We consider the following factors when determining the collectability of specific customer accounts: customer credit-worthiness, past transaction history with the customer, current economic industry trends, and changes in customer payment terms.  Our accounts receivable balance is typically due from Endo, our one large specialty pharmaceutical customer.  Endo has historically paid timely and has been a financially stable organization.  Due to the nature of the accounts receivable balance, we believe the risk of doubtful accounts is minimal.  If the financial condition of our customer were to deteriorate, adversely affecting its ability to make payments, additional allowances would be required.  We may provide for estimated uncollectible amounts through a charge to earnings and a credit to a valuation allowance. Balances that remain outstanding after we have used reasonable collection efforts are written off through a charge to the valuation allowance and a credit to accounts receivable. At September 30, 2016 and December 31, 2015 our accounts receivable balance was $3.8 million and $2.5 million, respectively, and was from one customer, Endo.

Deferred Revenue

Deferred revenue consists of the remaining $7.7 million related to the First Amendment with Endo of mark-up on cost of goods sold revenue for sales by non-affiliated sublicensees, approximately $62,000 related to nonrefundable upfront product license fees for product candidates for which we are providing continuing services related to product development and $100,000 related to a milestone payment withheld by Endo due to a foreign tax withholding which remains uncollected. Currently, the Company expects to recover the full amount. As of September 30, 2016 and December 31, 2015, deferred revenue was $7.9 million and $0.2 million, respectively.

Reimbursable Third-Party Development Costs

We accrued patent expenses for that are reimbursable by us under the License Agreement.  We capitalize certain patent costs related to estimated third-party development costs that are reimbursable under the License Agreement. As of September 30, 2016 and December 31, 2015, our net reimbursable third party patent expense accrual was approximately $25,000 and $20,000, respectively.

Third-Party Royalties

We have entered into licensing and royalty agreements with third parties and agreed to pay certain royalties on net sales of products for specific indications. The royalty rates differ from agreement to agreement and, in certain cases, have been redacted with the permission of the SEC.  No assumptions should be made that any disclosed royalty rate payable to a particular third party is the same or similar with respect to any royalty rate payable to any other third parties.  We accrue third-party royalty expenses on net sales reported to us by Endo. Third-party royalty costs are generally expensed in the quarter that Endo provides the written reports and related information to us; that is, generally one quarter following the quarter in which the underlying sales by Endo occurred. For the three and nine month periods ended September 30, 2016, third-party royalty expenses were $0.4 million and $1.2 million , respectively, and for the three and nine month periods ended September 30, 2015, third-party royalty expenses were $0.3 million and $1.0 million, respectively. Our third-party royalty expense under general and administrative expenses may increase if net sales by Endo and its partners for XIAFLEX and XIAPEX increase and potential new indications for CCH are approved.
 
Royalty Buy-Down

On March 31, 2012, we entered into an amendment to our existing agreement with Dr. Martin K. Gelbard, dated August 27, 2008, related to our future royalty obligations in connection with Peyronie’s disease. The amendment enables us to buy down a portion of our future royalty obligations in exchange for an initial cash payment of $1.5 million and five additional cash payments of $600,000, three of which have been paid as of September 30, 2016.  We are currently making the payments to buy down the future royalty obligations, which royalty obligations terminate five years after first commercial sale. The Company amortizes long-term contracts with finite lives in a manner that reflects the pattern in which the economic benefits of the assets are consumed or otherwise used up. Dr. Gelbard’s agreement is amortized based on an income forecast method by estimating sales of XIAFLEX for Peyronie’s disease on an annual basis as measured by the proportion of the total estimated sales over the five year period. Related to this agreement, we amortized approximately $247,000 and $740,000 for the three and nine months ended September 30, 2016, respectively, and $221,000 and $420,000 for the three and nine months ended September 30, 2015, respectively. The remaining capitalized balance as of September 30, 2016 was $3.1 million. We perform an evaluation of the recoverability of the carrying value to determine if facts and circumstances indicate that the carrying value of the assets may be impaired and if any adjustment is warranted. Based on our evaluation as of September 30, 2016, no impairment existed and no adjustment was warranted.
 
R&D Expenses

R&D expenses include, but are not limited to, internal costs, such as salaries and benefits, costs of materials, lab expenses, facility costs and overhead. R&D expenses also consist of third party costs, such as medical professional fees, product costs used in clinical trials, consulting fees and costs associated with clinical study arrangements. We may fund R&D at medical research institutions under agreements that are generally cancelable. All of these costs are charged to R&D as incurred, which may be measured by percentage of completion, contract milestones, patient enrollment, or the passage of time.

Clinical Trial Expenses

Our cost accruals for clinical trials are based on estimates of the services received and efforts expended pursuant to contracts with various clinical trial centers and clinical research organizations. In the normal course of business we contract with third parties to perform various clinical trial activities in the ongoing development of potential drugs. The financial terms of these agreements are subject to negotiation and vary from contract to contract and may result in uneven payment flows. Payments under the contracts depend on factors such as the achievement of certain events, the successful enrollment of patients, the completion of portions of the clinical trial, and other similar conditions. The objective of our accrual policy is to match the recording of expenses in our financial statements to the actual cost of services received and efforts expended. As such, expenses related to each patient enrolled in a clinical trial are recognized ratably beginning upon entry into the trial and over the course of the patient’s continued participation in the trial. In the event of early termination of a clinical trial, we accrue an amount based on our estimate of the remaining non-cancelable obligations associated with the winding down of the clinical trial. Our estimates and assumptions could differ significantly from the amounts that may actually be incurred.

Stock-Based Compensation

The Company has one stock-based compensation plan in effect. Accounting Standards Codification 718, Compensation - Stock Compensation (“ASC 718”), requires the recognition of compensation expense, using a fair-value based method, for costs related to all stock options including stock options and common stock issued to our employees and directors under our stock plans. ASC 718 requires companies to estimate the fair value of stock option awards on the date of grant using an option-pricing model. The value of the portion of the award that is ultimately expected to vest is recognized as expense on a straight-line basis over the requisite service periods in our condensed consolidated statements of operations.
 
Under ASC 718, we estimate the fair value of our employee stock option awards at the date of grant using the Black-Scholes option-pricing model, which requires the use of certain subjective assumptions. The most significant of these assumptions are our estimates of the expected volatility of the market price of our stock and the expected term of an award. When establishing an estimate of the expected term of an option award, we consider the vesting period for the award, our recent historical experience of employee stock option exercises (including forfeitures) and the expected volatility of our common stock.  As required under the accounting rules, we review our estimates at each grant date and, as a result, the valuation assumptions that we use to value employee stock-based awards granted in future periods may change. No stock options were granted during the nine months ended September 30, 2016 and 2015.

Further, ASC 718 requires that employee stock-based compensation costs be recognized over the requisite service period, or the vesting period, in a manner similar to all other forms of compensation paid to employees. The allocation of employee stock-based compensation costs to each operating expense line are estimated based on specific employee headcount information at each grant date and estimated stock option forfeiture rates and revised, if necessary, in future periods if actual employee headcount information or forfeitures differ materially from those estimates. As a result, the amount of employee stock-based compensation costs we recognize in each operating expense category in future periods may differ significantly from what we have recorded in the current period.

Stock-based compensation expense recognized in general and administrative expenses was approximately $33,000 and $100,000 for the three and nine months ended September 30, 2016, respectively, and $33,000 and $72,000 for the three and nine months ended September 30, 2015, respectively.

Stock Option Activity

A summary of our stock option activity during the nine months ended September 30, 2016 is presented below:

  
Shares
  
Weighted
Average
Exercise
Price
  
Weighted
Average
Remaining
Contractual
Term
  
Aggregate
Intrinsic
Value
 
Outstanding at January 1, 2016
  
562,000
  
$
11.91
   
2.51
  
$
17,456,220
 
Grants
  
-
   
-
   
-
   
-
 
Exercised
  
(255,000
)
  
2.08
   
-
   
-
 
Forfeitures or expirations
  
-
   
-
   
-
   
-
 
Outstanding at September 30, 2016
  
307,000
  
$
20.08
   
3.33
  
$
7,857,070
 
Exercisable at September 30, 2016
  
260,750
  
$
17.89
   
2.83
  
$
7,243,095
 
 
During the nine months ended September 30, 2016 and 2015, the Company received $0.5 million and $2.8 million, respectively, from stock options exercised by option holders.

Aggregate intrinsic value represents the total pre-tax intrinsic value based on the closing price of our common stock of $45.67 on September 30, 2016, which would have been received by the option holders had all option holders exercised their options as of that date. We have approximately $301,000 in unrecognized compensation cost related to stock options outstanding as of September 30, 2016, which we expect to recognize over the next 2.40 years.

Property and Equipment

Property and equipment are stated at cost, less accumulated depreciation. Machinery and equipment, furniture and fixtures, and autos are depreciated on a straight-line basis over their estimated useful lives of five to ten years. Leasehold improvements are amortized over the lesser of their estimated useful lives or the remaining life of the lease. As of September 30, 2016 and December 31, 2015, respectively, property and equipment were fully depreciated.

Comprehensive Income

For the three and nine months ended September 30, 2016 and 2015, respectively, we had no components of other comprehensive income other than net income itself.
 
Provision for Income Taxes

Deferred tax assets and liabilities are recognized based on the expected future tax consequences, using current tax rates, of temporary differences between the financial statement carrying amounts and the income tax basis of assets and liabilities. A valuation allowance is applied against any net deferred tax asset if, based on the weighted available evidence, it is more likely than not that some or all of the deferred tax assets will not be realized.

We use the asset and liability method of accounting for income taxes, as set forth in Accounting Standards Codification. Under this method, deferred income taxes, when required, are provided on the basis of the difference between the financial reporting and income tax basis of assets and liabilities at the statutory rates enacted for future periods. We classify interest associated with income taxes under interest expense and tax penalties under other expense.

The Company recognizes a tax benefit from an uncertain tax position only if it is more likely than not that the tax position will be sustained on examination by taxing authorities, based on the technical merits of the position. The tax benefit recognized in the consolidated financial statements from such position is measured based on the largest benefit that has a greater than 50% likelihood of being realized upon the ultimate settlement. As of September 30, 2016 and 2015, respectively, the Company has not recorded any unrecognized tax benefits.

Commitments and Contingencies

On November 1, 2016, the Company entered into an agreement with the Landlord to extend the term of the lease to the Headquarters for an additional one year period (the “Extended Lease Agreement”). The one year extension will end on November 30, 2017. Pursuant to the Extended Lease Agreement, the base rent is $10,757 per month and the Company may cancel the lease with three months’ prior written notice to the Landlord at any time during the term. The Extended Lease Agreement was filed with the SEC as Exhibit 10.1 to the Company’s Quarterly Report on Form 10Q on November 9, 2016.

New Accounting Pronouncements

The Financial Accounting Standards Board, or FASB, issued in May 2014, in August 2015, March 2016 and April 2016, respectively, Accounting Standards Updates No. 2014-09, No. 2015-14, No. 2016-08, and No. 2016-10 (the “ASUs”). These ASUs were issued in connection with revenue from contracts with customers. The new standard provides a five-step approach to be applied to all contracts with customers and also requires expanded disclosures about revenue recognition. In August 2015, the FASB deferred the effective date of the guidance to reporting periods, including interim periods, beginning after December 15, 2017, and will be applied retrospectively. Early adoption is not permitted. We are currently evaluating the timing, method of adoption and the expected impact that the standard could have on our consolidated financial statements and related disclosures. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.
                                                                          
In January 2016, the FASB issued new guidance on recognition and measurement of financial assets and financial liabilities. The new guidance will impact the accounting for equity investments, financial liabilities under the fair value option, and the presentation and disclosure requirements for financial instruments. All equity investments in unconsolidated entities (other than those accounted for under the equity method of accounting) will generally be measured at fair value with changes in fair value recognized through earnings. There will no longer be an available-for-sale classification (changes in fair value reported in other comprehensive income (loss) for equity securities with readily determinable fair values. In addition, the FASB clarified the need for a valuation allowance on deferred tax assets resulting from unrealized losses on available-for-sale debt securities. In general, the new guidance will require modified retrospective application to all outstanding instruments, with a cumulative effect adjustment recorded to opening retained earnings. This guidance will be effective for us on January 1, 2018. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.

In February 2016, FASB issued Accounting Standards Update (ASU) No. 2016-02, Leases (Topic 842). Under the new guidance, lessees will be required to recognize the following for all leases (with the exception of short-term leases) at the lease commencement date: a lease liability, which is a lessee’s obligation to make lease payments arising from a lease, measured on a discounted basis; and a right-of-use asset, which is an asset that represents the lessee’s right to use, or control the use of, a specified asset for the lease term. Under the new guidance, lessor accounting is largely unchanged. Certain targeted improvements were made to align, where necessary, lessor accounting with the lessee accounting model and Topic 606, Revenue from Contracts with Customers. The new lease guidance simplified the accounting for sale and leaseback transactions primarily because lessees must recognize lease assets and lease liabilities. Lessees will no longer be provided with a source of off-balance sheet financing. Public business entities should apply the amendments in ASU 2016-02 for fiscal years beginning after December 15, 2018, including interim periods within those fiscal years (i.e., January 1, 2019, for a calendar year entity). Early application is permitted.  Lessees (for capital and operating leases) and lessors (for sales-type, direct financing, and operating leases) must apply a modified retrospective transition approach for leases existing at, or entered into after, the beginning of the earliest comparative period presented in the financial statements. The modified retrospective approach would not require any transition accounting for leases that expired before the earliest comparative period presented. Lessees and lessors may not apply a full retrospective transition approach. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.
 
In March 2016, FASB issued ASU No. 2016-09 related to stock-based compensation. The new guidance simplifies the accounting for stock-based compensation transactions, including income tax consequences, classification of awards as either equity or liabilities, and classification on the statement of cash flows. This update is effective in fiscal years, including interim periods, beginning after December 15, 2016, and early adoption is permitted. We are currently evaluating this guidance and the impact it will have on the consolidated financial statements and related disclosures.

In May 2016, FASB issued ASU No. 2016-12, Revenue from Contracts with Customers (Topic 606): Narrow-Scope Improvements and Practical Expedients, which is intended to not change the core principle of the guidance in Topic 606, but rather affect only the narrow aspects of Topic 606 by reducing the potential for diversity in practice at initial application and by reducing the cost and complexity of applying Topic 606 both at transition and on an ongoing basis. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.

In June 2016, FASB issued ASU 2016-13, Financial Instruments - Credit Losses. The amendment revises the impairment model to utilize an expected loss methodology in place of the currently used incurred loss methodology, which will result in more timely recognition of losses on financial instruments, including, but not limited to, available for sale debt securities and accounts receivable. The Company is required to adopt this standard starting in the first quarter of fiscal year 2021. Early adoption is permitted. We are currently evaluating the impact of the adoption of this standard on our consolidated financial statements and related disclosures.
XML 18 R8.htm IDEA: XBRL DOCUMENT v3.5.0.2
NET INCOME PER SHARE
9 Months Ended
Sep. 30, 2016
NET INCOME PER SHARE [Abstract]  
NET INCOME PER SHARE
3.
NET INCOME PER SHARE

In accordance with Accounting Standards Codification 260, Earnings Per Share, basic net income per share amount is computed using the weighted-average number of shares of common stock outstanding during the periods presented, while diluted net income per share is computed using the sum of the weighted-average number of common and common equivalent shares outstanding. Common equivalent shares used in the computation of diluted earnings per share result from the assumed exercise of stock options using the treasury stock method.

The following table summarizes the number of common equivalent shares that were excluded for the calculation of diluted net income per share reported in the condensed consolidated statement of operations.

 
 
Three Months Ended
September 30,
  
Nine Months Ended
September 30,
 
 
 
2016
  
2015
  
2016
  
2015
 
Stock options
 
20,000
  
20,000
  
20,000
  
20,000
 
 
At September 30, 2016, the Company had 20,000 options, which have an exercise price of $29.21, and will vest upon the achievement of certain performance criteria, which have not yet been met.  These options expire on December 2, 2019.
XML 19 R9.htm IDEA: XBRL DOCUMENT v3.5.0.2
ACCOUNTS PAYABLE AND ACCRUED EXPENSES
9 Months Ended
Sep. 30, 2016
ACCOUNTS PAYABLE AND ACCRUED EXPENSES [Abstract]  
ACCOUNTS PAYABLE AND ACCRUED EXPENSES
4.
ACCOUNTS PAYABLE AND ACCRUED EXPENSES

Accounts payable and accrued expenses consisted of the following:

  
September 30,
2016
  
December 31,
2015
 
Trade accounts payable and accrued expenses
 
$
728,425
  
$
372,367
 
Accrued legal and other professional fees
  
66,775
   
74,138
 
Accrued payroll and related costs
  
196,667
   
164,504
 
Total
 
$
991,867
  
$
611,009
 
XML 20 R10.htm IDEA: XBRL DOCUMENT v3.5.0.2
PATENT COSTS
9 Months Ended
Sep. 30, 2016
PATENT COSTS [Abstract]  
PATENT COSTS
5.
PATENT COSTS

We amortize intangible assets with definite lives on a straight-line basis over their remaining estimated useful lives, ranging from one to twelve years, and review for impairment on a quarterly basis and when events or changes in circumstances indicate that the carrying amount of such assets may not be recoverable.  We analyze our intangible assets, specifically, capitalized patent costs, on an annual basis for any indicator that an impairment exist.

We capitalized legal patent costs related to patent prosecution and maintenance. For the nine months ended September 30, 2016, we increased our capitalized patent costs by approximately $23,300, based on reports provided to us by Endo. These patent costs are creditable against future royalty revenues. For each period presented below, net patent costs consisted of:

  
September 30,
2016
  
December 31,
2015
 
Patents
 
$
720,600
  
$
697,260
 
Accumulated amortization
  
(451,672
)
  
(422,054
)
  
$
268,928
  
$
275,206
 
 

 
The amortization expense for patents for the three and nine months ended September 30, 2016 was approximately $10,300 and $29,600, respectively, and the amortization expense for patents for the three and nine months ended September 30, 2015 was approximately $11,000 and $34,000, respectively. The estimated aggregate amortization expense for the remaining three months of 2016 and each of the years below is approximately as follows:

October 1, 2016 to December 31, 2016
 
$
10,600
 
2017
  
38,700
 
2018
  
38,700
 
2019
  
38,700
 
2020
  
27,400
 
Thereafter
 
$
114,800
 
XML 21 R11.htm IDEA: XBRL DOCUMENT v3.5.0.2
PROVISION FOR INCOME TAXES
9 Months Ended
Sep. 30, 2016
PROVISION FOR INCOME TAXES [Abstract]  
PROVISION FOR INCOME TAXES
6.
PROVISION FOR INCOME TAXES
 
In determining our provision for income taxes, we consider all available information, including operating results, ongoing tax planning, and forecasts of future taxable income. The significant components of the Company’s deferred tax assets consist of stock-based compensation and deferred revenues. For the three and nine months ended September 30, 2016, the provision for income taxes was $1.8 million and $4.5 million, respectively. As of September 30, 2016 and December 31, 2015, our remaining deferred tax assets were approximately $3.4 million and $0.6 million, respectively.
 
For the three and nine month periods ended September 30, 2015, the provision for income taxes was $1.5 million and $3.7 million, respectively.
 
As of September 30, 2016, the Company believes that there are no significant uncertain tax positions and no amounts have been recorded for interest and penalties.
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SUBSEQUENT EVENTS
9 Months Ended
Sep. 30, 2016
SUBSEQUENT EVENTS [Abstract]  
SUBSEQUENT EVENTS
7.
SUBSEQUENT EVENTS
 
On November 1, 2016, the Company entered into an agreement with the Landlord to extend the term of the lease to the Headquarters for an additional one year period (the “Extended Lease Agreement”). The one year extension will end on November 30, 2017. Pursuant to the Extended Lease Agreement, the base rent is $10,757 per month and the Company may cancel the lease with three months’ prior written notice to the Landlord at any time during the term. The Extended Lease Agreement was filed with the SEC as Exhibit 10.1 to the Company’s Quarterly Report on Form 10Q on November 9, 2016.
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SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Policies)
9 Months Ended
Sep. 30, 2016
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES [Abstract]  
Basis of Presentation
Basis of Presentation

The accompanying condensed consolidated financial statements are unaudited, but include all adjustments (consisting only of normal, recurring adjustments) which we consider necessary for a fair presentation of our financial position at such dates and the operating results and cash flows for those periods. Although we believe that the disclosures in our financial statements are adequate to make the information presented not misleading, certain information normally included in financial statements prepared in accordance with U.S. generally accepted accounting principles (“U.S. GAAP”) has been condensed or omitted pursuant to the rules and regulations of the Securities and Exchange Commission (the “SEC”) for quarterly reporting.
 
The information included in this Report should be read in conjunction with the risk factors discussed in “Part I, Item 1A. Risk Factors” in our Quarterly Reports on Form 10Q for the periods ended March 31, 2016 and June 30, 2016 filed with the SEC on May 10, 2016 and August 9, 2016, respectively and our Annual Report on Form 10-K for the period ended December 31, 2015 filed with the SEC on March 14, 2016.
Principles of Consolidation
Principles of Consolidation

The condensed consolidated financial statements include the accounts of the Company and its subsidiary, Advance Biofactures Corp. (“ABC-NY”). All intercompany balances and transactions have been eliminated.
Critical Accounting Policies, Estimates and Assumptions
Critical Accounting Policies, Estimates and Assumptions

The preparation of condensed consolidated financial statements in conformity with U.S. GAAP requires the use of management’s estimates and assumptions that affect the amounts reported in the condensed consolidated financial statements and accompanying notes. The Company makes certain assumptions and estimates for its deferred tax assets and deferred royalty buy-down. For further details see notes “Provision for Income Taxes” and “Third-Party Royalties and Royalty Buy-Down.” Actual results may differ from those estimates.
Cash, Cash Equivalents and Investments
Cash, Cash Equivalents and Investments

Cash equivalents include only securities having a maturity of three months or less at the time of purchase. Investments are stated on an amortized cost basis. The Company limits its credit risk associated with cash, cash equivalents and investments by placing its investments with banks it believes are highly creditworthy and with highly rated money market funds, certificates of deposit and municipal bonds. All investments are classified as held to maturity. As of September 30, 2016 and December 31, 2015, the aggregate fair value of these investments was $46.5 million and $31.9 million, respectively.
Fair Value Measurements
Fair Value Measurements

Management believes that the carrying amounts of the Company’s financial instruments, including cash, cash equivalents, held to maturity investments, accounts receivable, accounts payable and accrued expenses approximate fair value due to the short-term nature of those instruments. As of September 30, 2016 and December 31, 2015, there were no recorded unrealized gains or losses on our investments as they are held to maturity. As of September 30, 2016, amortized cost basis of the investments approximate their fair value. At September 30, 2016 and December 31, 2015, the amortized premium included in interest income was $446,000 and $316,000, respectively.

The following table presents the Company’s schedule of maturities at September 30, 2016 and December 31, 2015:

  
Maturities as of
September 30, 2016
  
Maturities as of
December 31, 2015
 
       
  
1 Year or Less
  
Greater than
1 Year
  
1 Year or
Less
  
Greater than 1
Year
 
                 
Municipal bonds
 
$
6,917,696
  
$
-
  
$
6,461,216
  
$
155,826
 
                 
Corporate Bonds
  
31,218,996
   
1,194,049
   
9,882,285
   
1,597,715
 
                 
Certificates of deposit
  
6,938,878
   
249,050
   
12,004,041
   
1,843,000
 
Total
 
$
45,075,570
  
$
1,443,099
  
$
28,347,542
  
$
3,596,541
 
 
The authoritative literature for fair value measurements established a three-tier fair value hierarchy, which prioritizes the inputs in measuring fair value. These tiers are as follows: Level 1, defined as observable inputs such as quoted market prices in active markets; Level 2, defined as inputs other than the quoted prices in active markets that are either directly or indirectly observable; and Level 3, defined as significant unobservable inputs (entity developed assumptions) in which little or no market data exists.

As of September 30, 2016, the Company held certain investments that are required to be measured at fair value on a recurring basis. The following tables present the Company’s fair value hierarchy for these financial assets as of September 30, 2016 and December 31, 2015:

September 30, 2016
Type of Instrument
 
Fair Value
  
Level 1
  
Level 2
  
Level 3
 
                  
Cash equivalents
Institutional Money Market
 
$
1,894,904
  
$
1,894,904
   
-
   
-
 
                  
Investments
Municipal Bonds
  
6,917,696
   
-
  
$
6,917,696
   
-
 
                  
Investments
Corporate Bonds
  
32,413,045
   
-
   
32,413,045
   
-
 
                  
Investments
Certificates of Deposit
  
7,187,928
   
7,187,928
   
-
   
-
 
              
December 31, 2015
Type of Instrument
 
Fair Value
  
Level 1
  
Level 2
  
Level 3
 
                  
Cash equivalents
Institutional Money Market
 
$
715,784
  
$
715,784
   
-
   
-
 
                  
Investments
Municipal Bonds
  
6,617,042
   
-
  
$
6,617,042
   
-
 
                  
Investments
Corporate Bonds
  
11,480,000
   
-
   
11,480,000
   
-
 
                  
Investments
Certificates of Deposit
  
13,847,041
   
13,847,041
   
-
   
-
 
Concentration of Credit Risk and Major Customers
Concentration of Credit Risk and Major Customers

The Company maintains bank account balances, which, at times, may exceed insured limits. The Company has not experienced any losses with these accounts and believes that it is not exposed to any significant credit risk on cash.

The Company maintains its investment in FDIC insured certificates of deposits with several banks, pre-refunded municipal bonds, municipal bonds and corporate bonds.

The Company is currently dependent on one customer, Endo, who generates almost all its revenues. For the three and nine months ended September 30, 2016, licensing, sublicensing, milestones and royalty revenues under the License Agreement with Endo were approximately $6.9 million and $19.6 million, respectively, and for the three and nine months ended September 30, 2015, the licensing, sublicensing, milestones and royalty revenues under the License Agreement with Endo were approximately $6.3 million and $16.6 million, respectively.

At September 30, 2016 and December 31, 2015, our accounts receivable balances were $3.8 million and $2.5 million, respectively.
Revenue Recognition
Revenue Recognition
 
We currently recognize revenues resulting from the licensing and sublicensing of the use of our technology and from services we sometimes perform in connection with the licensed technology under the guidance of Accounting Standards Codification 605, Revenue Recognition (“ASC 605”).

If we determine that separate elements exist in a revenue arrangement under ASC 605, we recognize revenue for delivered elements only when the fair values of undelivered elements are known, when the associated earnings process is complete, when payment is reasonably assured and, to the extent the milestone amount relates to our performance obligation, when our customer confirms that we have met the requirements under the terms of the agreement.
Royalty / Mark-Up on Cost of Goods Sold
Royalty / Mark-Up on Cost of Goods Sold

For those arrangements for which royalty and mark-up on cost of goods sold information becomes available and collectability is reasonably assured, we recognize revenue during the applicable period in which it is earned. For interim quarterly and year-end reporting purposes, when collectability is reasonably assured, but a reasonable estimate of royalty and mark-up on cost of goods sold cannot be made, the royalty and mark-up on cost of goods sold are generally recognized in the quarter that the applicable licensee provides the written report and related information to us.

Under the License Agreement, we do not participate in the selling, marketing or manufacturing of products for which we receive royalties and a mark-up on the cost of goods sold. The royalty and mark-up on cost of goods sold will generally be recognized in the quarter that Endo provides the written reports and related information to us; that is, royalty and mark-up on cost of goods sold are generally recognized one quarter following the quarter in which the underlying sales by Endo occurred. The royalties payable by Endo to us are subject to set-off for certain patent costs.

Pursuant to the First Amendment with Endo, in exchange for a $8.25 million lump sum payment, we will not receive future additional mark-up on cost of goods sold for sales by non-affiliated sublicensees of Endo outside of the U.S.; provided, however, that Endo will still be required to pay a mark-up on cost of goods sold for sales made in the “Endo Territory,” which includes sales made in the U.S. and sales made in any other country where Endo sells the product directly or through affiliated sublicensees. We received this $8.25 million lump sum payment in February 2016. We classified this payment as deferred revenue in our balance sheet and began recognizing this income over time in the second quarter of 2016 based on sales by non-affiliated sublicensees of Endo outside of the U.S. according to our revenue recognition policy. We recognized approximately $274,000 and $546,000 for the three and nine months ended September 30, 2016, and zero in each of the 2015 corresponding periods.
Licensing Revenue
Licensing Revenue

We include revenue recognized from upfront licensing, sublicensing and milestone payments in “License Revenues” in our condensed consolidated statements of income in this Quarterly Report on Form 10-Q.

Upfront License and Sublicensing Fees

We generally recognize revenue from upfront licensing and sublicensing fees when the license or sublicense agreement is signed, we have completed the earnings process and we have no ongoing performance obligation with respect to the arrangement. We recognized licensing fees related to the exercise of an opt-in right by Endo for the human lipoma indication of $750,000 for the three and nine months ended September 30, 2016 as compared to zero in each of the 2015 periods. Nonrefundable upfront technology license fees for product candidates for which we are providing continuing services related to product development are deferred and recognized as revenue over the development period. We recognized deferred revenue of $12,345 and $37,034 for the three and nine months ended September 30, 2016, respectively, and $12,345 and $37,034 for the three and nine months ended September 30, 2015, respectively.

Milestones

Milestones, in the form of additional license fees, typically represent nonrefundable payments to be received in conjunction with the achievement of a specific event identified in the license or sublicense agreement, such as completion of specified development activities and/or regulatory submissions and/or approvals. We believe that a milestone represents the culmination of a distinct earnings process when it is not associated with ongoing research, development or other performance on our part. We recognize such milestones as revenue when they become due and collection is reasonably assured. When a milestone does not represent the culmination of a distinct earnings process, we recognize revenue in a manner similar to that of an upfront license fee.
 
The timing and amount of revenue that we recognize from licenses of technology, either from upfront fees or milestones where we are providing continuing services related to product development, are primarily dependent upon our estimates of the development period. We define the development period as the point from which research activities commence up to regulatory approval of either our or our partners’ submission, assuming no further research is necessary. As product candidates move through the development process, it is necessary to revise these estimates to consider changes to the product development cycle, such as changes in the clinical development plan, regulatory requirements, or various other factors, many of which may be outside of our control. Should the U.S. Food and Drug Administration (“FDA”) or other regulatory agencies require additional data or information, we would adjust our development period estimates accordingly. The impact on revenue of changes in our estimates and the timing thereof is recognized prospectively over the remaining estimated product development period. We did not recognize any milestone revenue in the three and nine month periods ended September 30, 2016. Milestone revenue recognized for the three and nine months ended September 30, 2015 was $1.0 million in each period.  The $1.0 million milestone revenue recognized in the 2015 periods related to the first commercial sale of XIAFLEX by Asahi for the treatment of Dupuytren's contracture in Japan.
Treasury Stock
Treasury Stock
 
The Company accounts for treasury stock under the cost method and includes treasury stock as a component of stockholders’ equity. For the nine months ended September 30, 2016, we repurchased 24,020 shares at an average price of $37.39 as compared to the repurchase of 27,433 shares at an average price of $43.07 in the corresponding 2015 period.
Receivables and Doubtful Accounts
Receivables and Doubtful Accounts
 
Trade accounts receivable are stated at the amount the Company expects to collect. We may maintain allowances for doubtful accounts for estimated losses resulting from the inability of our customers to make required payments. We consider the following factors when determining the collectability of specific customer accounts: customer credit-worthiness, past transaction history with the customer, current economic industry trends, and changes in customer payment terms.  Our accounts receivable balance is typically due from Endo, our one large specialty pharmaceutical customer.  Endo has historically paid timely and has been a financially stable organization.  Due to the nature of the accounts receivable balance, we believe the risk of doubtful accounts is minimal.  If the financial condition of our customer were to deteriorate, adversely affecting its ability to make payments, additional allowances would be required.  We may provide for estimated uncollectible amounts through a charge to earnings and a credit to a valuation allowance. Balances that remain outstanding after we have used reasonable collection efforts are written off through a charge to the valuation allowance and a credit to accounts receivable. At September 30, 2016 and December 31, 2015 our accounts receivable balance was $3.8 million and $2.5 million, respectively, and was from one customer, Endo.
Deferred Revenue
Deferred Revenue

Deferred revenue consists of the remaining $7.7 million related to the First Amendment with Endo of mark-up on cost of goods sold revenue for sales by non-affiliated sublicensees, approximately $62,000 related to nonrefundable upfront product license fees for product candidates for which we are providing continuing services related to product development and $100,000 related to a milestone payment withheld by Endo due to a foreign tax withholding which remains uncollected. Currently, the Company expects to recover the full amount. As of September 30, 2016 and December 31, 2015, deferred revenue was $7.9 million and $0.2 million, respectively.
Reimbursable Third-Party Development Costs
Reimbursable Third-Party Development Costs

We accrued patent expenses for that are reimbursable by us under the License Agreement.  We capitalize certain patent costs related to estimated third-party development costs that are reimbursable under the License Agreement. As of September 30, 2016 and December 31, 2015, our net reimbursable third party patent expense accrual was approximately $25,000 and $20,000, respectively.
Third-Party Royalties
Third-Party Royalties

We have entered into licensing and royalty agreements with third parties and agreed to pay certain royalties on net sales of products for specific indications. The royalty rates differ from agreement to agreement and, in certain cases, have been redacted with the permission of the SEC.  No assumptions should be made that any disclosed royalty rate payable to a particular third party is the same or similar with respect to any royalty rate payable to any other third parties.  We accrue third-party royalty expenses on net sales reported to us by Endo. Third-party royalty costs are generally expensed in the quarter that Endo provides the written reports and related information to us; that is, generally one quarter following the quarter in which the underlying sales by Endo occurred. For the three and nine month periods ended September 30, 2016, third-party royalty expenses were $0.4 million and $1.2 million , respectively, and for the three and nine month periods ended September 30, 2015, third-party royalty expenses were $0.3 million and $1.0 million, respectively. Our third-party royalty expense under general and administrative expenses may increase if net sales by Endo and its partners for XIAFLEX and XIAPEX increase and potential new indications for CCH are approved.
Royalty Buy-Down
Royalty Buy-Down

On March 31, 2012, we entered into an amendment to our existing agreement with Dr. Martin K. Gelbard, dated August 27, 2008, related to our future royalty obligations in connection with Peyronie’s disease. The amendment enables us to buy down a portion of our future royalty obligations in exchange for an initial cash payment of $1.5 million and five additional cash payments of $600,000, three of which have been paid as of September 30, 2016.  We are currently making the payments to buy down the future royalty obligations, which royalty obligations terminate five years after first commercial sale. The Company amortizes long-term contracts with finite lives in a manner that reflects the pattern in which the economic benefits of the assets are consumed or otherwise used up. Dr. Gelbard’s agreement is amortized based on an income forecast method by estimating sales of XIAFLEX for Peyronie’s disease on an annual basis as measured by the proportion of the total estimated sales over the five year period. Related to this agreement, we amortized approximately $247,000 and $740,000 for the three and nine months ended September 30, 2016, respectively, and $221,000 and $420,000 for the three and nine months ended September 30, 2015, respectively. The remaining capitalized balance as of September 30, 2016 was $3.1 million. We perform an evaluation of the recoverability of the carrying value to determine if facts and circumstances indicate that the carrying value of the assets may be impaired and if any adjustment is warranted. Based on our evaluation as of September 30, 2016, no impairment existed and no adjustment was warranted.
R&D Expenses
R&D Expenses

R&D expenses include, but are not limited to, internal costs, such as salaries and benefits, costs of materials, lab expenses, facility costs and overhead. R&D expenses also consist of third party costs, such as medical professional fees, product costs used in clinical trials, consulting fees and costs associated with clinical study arrangements. We may fund R&D at medical research institutions under agreements that are generally cancelable. All of these costs are charged to R&D as incurred, which may be measured by percentage of completion, contract milestones, patient enrollment, or the passage of time.
Clinical Trial Expenses
Clinical Trial Expenses

Our cost accruals for clinical trials are based on estimates of the services received and efforts expended pursuant to contracts with various clinical trial centers and clinical research organizations. In the normal course of business we contract with third parties to perform various clinical trial activities in the ongoing development of potential drugs. The financial terms of these agreements are subject to negotiation and vary from contract to contract and may result in uneven payment flows. Payments under the contracts depend on factors such as the achievement of certain events, the successful enrollment of patients, the completion of portions of the clinical trial, and other similar conditions. The objective of our accrual policy is to match the recording of expenses in our financial statements to the actual cost of services received and efforts expended. As such, expenses related to each patient enrolled in a clinical trial are recognized ratably beginning upon entry into the trial and over the course of the patient’s continued participation in the trial. In the event of early termination of a clinical trial, we accrue an amount based on our estimate of the remaining non-cancelable obligations associated with the winding down of the clinical trial. Our estimates and assumptions could differ significantly from the amounts that may actually be incurred.
Stock-Based Compensation
Stock-Based Compensation

The Company has one stock-based compensation plan in effect. Accounting Standards Codification 718, Compensation - Stock Compensation (“ASC 718”), requires the recognition of compensation expense, using a fair-value based method, for costs related to all stock options including stock options and common stock issued to our employees and directors under our stock plans. ASC 718 requires companies to estimate the fair value of stock option awards on the date of grant using an option-pricing model. The value of the portion of the award that is ultimately expected to vest is recognized as expense on a straight-line basis over the requisite service periods in our condensed consolidated statements of operations.
 
Under ASC 718, we estimate the fair value of our employee stock option awards at the date of grant using the Black-Scholes option-pricing model, which requires the use of certain subjective assumptions. The most significant of these assumptions are our estimates of the expected volatility of the market price of our stock and the expected term of an award. When establishing an estimate of the expected term of an option award, we consider the vesting period for the award, our recent historical experience of employee stock option exercises (including forfeitures) and the expected volatility of our common stock.  As required under the accounting rules, we review our estimates at each grant date and, as a result, the valuation assumptions that we use to value employee stock-based awards granted in future periods may change. No stock options were granted during the nine months ended September 30, 2016 and 2015.

Further, ASC 718 requires that employee stock-based compensation costs be recognized over the requisite service period, or the vesting period, in a manner similar to all other forms of compensation paid to employees. The allocation of employee stock-based compensation costs to each operating expense line are estimated based on specific employee headcount information at each grant date and estimated stock option forfeiture rates and revised, if necessary, in future periods if actual employee headcount information or forfeitures differ materially from those estimates. As a result, the amount of employee stock-based compensation costs we recognize in each operating expense category in future periods may differ significantly from what we have recorded in the current period.

Stock-based compensation expense recognized in general and administrative expenses was approximately $33,000 and $100,000 for the three and nine months ended September 30, 2016, respectively, and $33,000 and $72,000 for the three and nine months ended September 30, 2015, respectively.

Stock Option Activity

A summary of our stock option activity during the nine months ended September 30, 2016 is presented below:

  
Shares
  
Weighted
Average
Exercise
Price
  
Weighted
Average
Remaining
Contractual
Term
  
Aggregate
Intrinsic
Value
 
Outstanding at January 1, 2016
  
562,000
  
$
11.91
   
2.51
  
$
17,456,220
 
Grants
  
-
   
-
   
-
   
-
 
Exercised
  
(255,000
)
  
2.08
   
-
   
-
 
Forfeitures or expirations
  
-
   
-
   
-
   
-
 
Outstanding at September 30, 2016
  
307,000
  
$
20.08
   
3.33
  
$
7,857,070
 
Exercisable at September 30, 2016
  
260,750
  
$
17.89
   
2.83
  
$
7,243,095
 
 
During the nine months ended September 30, 2016 and 2015, the Company received $0.5 million and $2.8 million, respectively, from stock options exercised by option holders.

Aggregate intrinsic value represents the total pre-tax intrinsic value based on the closing price of our common stock of $45.67 on September 30, 2016, which would have been received by the option holders had all option holders exercised their options as of that date. We have approximately $301,000 in unrecognized compensation cost related to stock options outstanding as of September 30, 2016, which we expect to recognize over the next 2.40 years.
Property and Equipment
Property and Equipment

Property and equipment are stated at cost, less accumulated depreciation. Machinery and equipment, furniture and fixtures, and autos are depreciated on a straight-line basis over their estimated useful lives of five to ten years. Leasehold improvements are amortized over the lesser of their estimated useful lives or the remaining life of the lease. As of September 30, 2016 and December 31, 2015, respectively, property and equipment were fully depreciated.
Comprehensive Income
Comprehensive Income

For the three and nine months ended September 30, 2016 and 2015, respectively, we had no components of other comprehensive income other than net income itself.
Provision for Income Taxes
Provision for Income Taxes

Deferred tax assets and liabilities are recognized based on the expected future tax consequences, using current tax rates, of temporary differences between the financial statement carrying amounts and the income tax basis of assets and liabilities. A valuation allowance is applied against any net deferred tax asset if, based on the weighted available evidence, it is more likely than not that some or all of the deferred tax assets will not be realized.

We use the asset and liability method of accounting for income taxes, as set forth in Accounting Standards Codification. Under this method, deferred income taxes, when required, are provided on the basis of the difference between the financial reporting and income tax basis of assets and liabilities at the statutory rates enacted for future periods. We classify interest associated with income taxes under interest expense and tax penalties under other expense.

The Company recognizes a tax benefit from an uncertain tax position only if it is more likely than not that the tax position will be sustained on examination by taxing authorities, based on the technical merits of the position. The tax benefit recognized in the consolidated financial statements from such position is measured based on the largest benefit that has a greater than 50% likelihood of being realized upon the ultimate settlement. As of September 30, 2016 and 2015, respectively, the Company has not recorded any unrecognized tax benefits.
Commitments and Contingencies
Commitments and Contingencies

On November 1, 2016, the Company entered into an agreement with the Landlord to extend the term of the lease to the Headquarters for an additional one year period (the “Extended Lease Agreement”). The one year extension will end on November 30, 2017. Pursuant to the Extended Lease Agreement, the base rent is $10,757 per month and the Company may cancel the lease with three months’ prior written notice to the Landlord at any time during the term. The Extended Lease Agreement was filed with the SEC as Exhibit 10.1 to the Company’s Quarterly Report on Form 10Q on November 9, 2016.
New Accounting Pronouncements
New Accounting Pronouncements

The Financial Accounting Standards Board, or FASB, issued in May 2014, in August 2015, March 2016 and April 2016, respectively, Accounting Standards Updates No. 2014-09, No. 2015-14, No. 2016-08, and No. 2016-10 (the “ASUs”). These ASUs were issued in connection with revenue from contracts with customers. The new standard provides a five-step approach to be applied to all contracts with customers and also requires expanded disclosures about revenue recognition. In August 2015, the FASB deferred the effective date of the guidance to reporting periods, including interim periods, beginning after December 15, 2017, and will be applied retrospectively. Early adoption is not permitted. We are currently evaluating the timing, method of adoption and the expected impact that the standard could have on our consolidated financial statements and related disclosures. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.
                                                                          
In January 2016, the FASB issued new guidance on recognition and measurement of financial assets and financial liabilities. The new guidance will impact the accounting for equity investments, financial liabilities under the fair value option, and the presentation and disclosure requirements for financial instruments. All equity investments in unconsolidated entities (other than those accounted for under the equity method of accounting) will generally be measured at fair value with changes in fair value recognized through earnings. There will no longer be an available-for-sale classification (changes in fair value reported in other comprehensive income (loss) for equity securities with readily determinable fair values. In addition, the FASB clarified the need for a valuation allowance on deferred tax assets resulting from unrealized losses on available-for-sale debt securities. In general, the new guidance will require modified retrospective application to all outstanding instruments, with a cumulative effect adjustment recorded to opening retained earnings. This guidance will be effective for us on January 1, 2018. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.

In February 2016, FASB issued Accounting Standards Update (ASU) No. 2016-02, Leases (Topic 842). Under the new guidance, lessees will be required to recognize the following for all leases (with the exception of short-term leases) at the lease commencement date: a lease liability, which is a lessee’s obligation to make lease payments arising from a lease, measured on a discounted basis; and a right-of-use asset, which is an asset that represents the lessee’s right to use, or control the use of, a specified asset for the lease term. Under the new guidance, lessor accounting is largely unchanged. Certain targeted improvements were made to align, where necessary, lessor accounting with the lessee accounting model and Topic 606, Revenue from Contracts with Customers. The new lease guidance simplified the accounting for sale and leaseback transactions primarily because lessees must recognize lease assets and lease liabilities. Lessees will no longer be provided with a source of off-balance sheet financing. Public business entities should apply the amendments in ASU 2016-02 for fiscal years beginning after December 15, 2018, including interim periods within those fiscal years (i.e., January 1, 2019, for a calendar year entity). Early application is permitted.  Lessees (for capital and operating leases) and lessors (for sales-type, direct financing, and operating leases) must apply a modified retrospective transition approach for leases existing at, or entered into after, the beginning of the earliest comparative period presented in the financial statements. The modified retrospective approach would not require any transition accounting for leases that expired before the earliest comparative period presented. Lessees and lessors may not apply a full retrospective transition approach. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.
 
In March 2016, FASB issued ASU No. 2016-09 related to stock-based compensation. The new guidance simplifies the accounting for stock-based compensation transactions, including income tax consequences, classification of awards as either equity or liabilities, and classification on the statement of cash flows. This update is effective in fiscal years, including interim periods, beginning after December 15, 2016, and early adoption is permitted. We are currently evaluating this guidance and the impact it will have on the consolidated financial statements and related disclosures.

In May 2016, FASB issued ASU No. 2016-12, Revenue from Contracts with Customers (Topic 606): Narrow-Scope Improvements and Practical Expedients, which is intended to not change the core principle of the guidance in Topic 606, but rather affect only the narrow aspects of Topic 606 by reducing the potential for diversity in practice at initial application and by reducing the cost and complexity of applying Topic 606 both at transition and on an ongoing basis. We are currently evaluating the expected impact that the standard could have on our consolidated financial statements and related disclosures.

In June 2016, FASB issued ASU 2016-13, Financial Instruments - Credit Losses. The amendment revises the impairment model to utilize an expected loss methodology in place of the currently used incurred loss methodology, which will result in more timely recognition of losses on financial instruments, including, but not limited to, available for sale debt securities and accounts receivable. The Company is required to adopt this standard starting in the first quarter of fiscal year 2021. Early adoption is permitted. We are currently evaluating the impact of the adoption of this standard on our consolidated financial statements and related disclosures.
XML 24 R14.htm IDEA: XBRL DOCUMENT v3.5.0.2
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Tables)
9 Months Ended
Sep. 30, 2016
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES [Abstract]  
Schedule of Maturities
The following table presents the Company’s schedule of maturities at September 30, 2016 and December 31, 2015:

  
Maturities as of
September 30, 2016
  
Maturities as of
December 31, 2015
 
       
  
1 Year or Less
  
Greater than
1 Year
  
1 Year or
Less
  
Greater than 1
Year
 
                 
Municipal bonds
 
$
6,917,696
  
$
-
  
$
6,461,216
  
$
155,826
 
                 
Corporate Bonds
  
31,218,996
   
1,194,049
   
9,882,285
   
1,597,715
 
                 
Certificates of deposit
  
6,938,878
   
249,050
   
12,004,041
   
1,843,000
 
Total
 
$
45,075,570
  
$
1,443,099
  
$
28,347,542
  
$
3,596,541
 
Fair Value Assets Measured on Recurring Basis
The following tables present the Company’s fair value hierarchy for these financial assets as of September 30, 2016 and December 31, 2015:

September 30, 2016
Type of Instrument
 
Fair Value
  
Level 1
  
Level 2
  
Level 3
 
                  
Cash equivalents
Institutional Money Market
 
$
1,894,904
  
$
1,894,904
   
-
   
-
 
                  
Investments
Municipal Bonds
  
6,917,696
   
-
  
$
6,917,696
   
-
 
                  
Investments
Corporate Bonds
  
32,413,045
   
-
   
32,413,045
   
-
 
                  
Investments
Certificates of Deposit
  
7,187,928
   
7,187,928
   
-
   
-
 
              
December 31, 2015
Type of Instrument
 
Fair Value
  
Level 1
  
Level 2
  
Level 3
 
                  
Cash equivalents
Institutional Money Market
 
$
715,784
  
$
715,784
   
-
   
-
 
                  
Investments
Municipal Bonds
  
6,617,042
   
-
  
$
6,617,042
   
-
 
                  
Investments
Corporate Bonds
  
11,480,000
   
-
   
11,480,000
   
-
 
                  
Investments
Certificates of Deposit
  
13,847,041
   
13,847,041
   
-
   
-
 
Summary of Stock Option Activity
A summary of our stock option activity during the nine months ended September 30, 2016 is presented below:

  
Shares
  
Weighted
Average
Exercise
Price
  
Weighted
Average
Remaining
Contractual
Term
  
Aggregate
Intrinsic
Value
 
Outstanding at January 1, 2016
  
562,000
  
$
11.91
   
2.51
  
$
17,456,220
 
Grants
  
-
   
-
   
-
   
-
 
Exercised
  
(255,000
)
  
2.08
   
-
   
-
 
Forfeitures or expirations
  
-
   
-
   
-
   
-
 
Outstanding at September 30, 2016
  
307,000
  
$
20.08
   
3.33
  
$
7,857,070
 
Exercisable at September 30, 2016
  
260,750
  
$
17.89
   
2.83
  
$
7,243,095
 
XML 25 R15.htm IDEA: XBRL DOCUMENT v3.5.0.2
NET INCOME PER SHARE (Tables)
9 Months Ended
Sep. 30, 2016
NET INCOME PER SHARE [Abstract]  
Number of Common Equivalent Shares Excluded from the Calculation of Diluted Net Income Per Share
The following table summarizes the number of common equivalent shares that were excluded for the calculation of diluted net income per share reported in the condensed consolidated statement of operations.

 
 
Three Months Ended
September 30,
  
Nine Months Ended
September 30,
 
 
 
2016
  
2015
  
2016
  
2015
 
Stock options
 
20,000
  
20,000
  
20,000
  
20,000
 
XML 26 R16.htm IDEA: XBRL DOCUMENT v3.5.0.2
ACCOUNTS PAYABLE AND ACCRUED EXPENSES (Tables)
9 Months Ended
Sep. 30, 2016
ACCOUNTS PAYABLE AND ACCRUED EXPENSES [Abstract]  
Accounts Payable and Accrued Expenses
Accounts payable and accrued expenses consisted of the following:

  
September 30,
2016
  
December 31,
2015
 
Trade accounts payable and accrued expenses
 
$
728,425
  
$
372,367
 
Accrued legal and other professional fees
  
66,775
   
74,138
 
Accrued payroll and related costs
  
196,667
   
164,504
 
Total
 
$
991,867
  
$
611,009
 
XML 27 R17.htm IDEA: XBRL DOCUMENT v3.5.0.2
PATENT COSTS (Tables)
9 Months Ended
Sep. 30, 2016
PATENT COSTS [Abstract]  
Net Patent Costs
For each period presented below, net patent costs consisted of:

  
September 30,
2016
  
December 31,
2015
 
Patents
 
$
720,600
  
$
697,260
 
Accumulated amortization
  
(451,672
)
  
(422,054
)
  
$
268,928
  
$
275,206
 
Estimated Aggregate Future Amortization Expense
The estimated aggregate amortization expense for the remaining three months of 2016 and each of the years below is approximately as follows:

October 1, 2016 to December 31, 2016
 
$
10,600
 
2017
  
38,700
 
2018
  
38,700
 
2019
  
38,700
 
2020
  
27,400
 
Thereafter
 
$
114,800
 
XML 28 R18.htm IDEA: XBRL DOCUMENT v3.5.0.2
ORGANIZATION AND DESCRIPTION OF BUSINESS (Details) - Endo [Member] - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
Feb. 29, 2016
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Feb. 05, 2016
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]            
Deferred revenue on licensing agreements           $ 8,250,000
Proceeds from licensing agreement $ 8,250,000 $ 750,000 $ 0 $ 750,000 $ 0  
Opt-in fee receivable for each indication           500,000
Regular opt-in fee receivable for each indication           $ 750,000
XML 29 R19.htm IDEA: XBRL DOCUMENT v3.5.0.2
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Nov. 01, 2016
USD ($)
Feb. 29, 2016
USD ($)
Sep. 30, 2016
USD ($)
$ / shares
shares
Sep. 30, 2015
USD ($)
Mar. 31, 2012
USD ($)
Sep. 30, 2016
USD ($)
Payment
Plan
$ / shares
shares
Sep. 30, 2015
USD ($)
$ / shares
shares
Dec. 31, 2015
USD ($)
$ / shares
shares
Feb. 05, 2016
USD ($)
Cash, Cash Equivalents and Investments [Abstract]                  
Aggregate fair value of investments     $ 46,500,000     $ 46,500,000   $ 31,900,000  
Fair Value Measurements [Abstract]                  
Unrealized gains (losses) on investments           0   0  
Amortized premium included in interest income           (446,000)   (316,000)  
Schedule of Held-to-maturity Securities [Line Items]                  
Held-to-maturity securities, current     45,075,570     45,075,570   28,347,542  
Held-to-maturity securities, noncurrent     1,443,099     1,443,099   3,596,541  
Concentration Risk [Line Items]                  
Royalty revenue     6,119,815 $ 5,277,494   18,843,273 $ 15,574,234    
Accounts receivable     3,846,752     3,846,752   2,547,920  
Milestones Revenue [Abstract]                  
Recognized milestone revenue     0 1,000,000   0 1,000,000    
Deferred Revenue [Abstract]                  
Deferred revenue recognized     12,345 12,345   37,034 $ 37,034    
Deferred revenue     7,900,000     7,900,000   200,000  
Nonrefundable upfront product license fees           62,000      
Deferred revenue from foreign tax withholding     100,000     $ 100,000      
Treasury Stock [Abstract]                  
Treasury stock purchased (in shares) | shares           24,020 27,433    
Average price of share (in dollars per share) | $ / shares           $ 37.39 $ 43.07    
Reimbursable Third Party Development Costs [Abstract]                  
Accrued patent costs     25,000     $ 25,000   20,000  
Third Party Royalties [Abstract]                  
Royalty expenses     400,000 300,000   1,200,000 $ 1,000,000    
Royalty Buy Down [Abstract]                  
Payment for royalty buy down         $ 1,500,000 $ 600,000      
Number of additional cash payments for royalty buy down | Payment           5      
Number of cash payments made for royalty obligation | Payment           3      
Amount amortized related to agreement     247,000 221,000   $ 740,000 420,000    
Deferred costs amortization period           5 years      
Deferred royalty buy-down - long term     $ 3,100,000     $ 3,100,000      
Share-based Compensation [Abstract]                  
Number of stock based compensation plans in effect | Plan           1      
Additional Disclosures [Abstract]                  
Proceeds from stock option exercises           $ 529,300 2,813,984    
Closing price of company stock (in dollars per share) | $ / shares     $ 45.67     $ 45.67      
Comprehensive Income [Abstract]                  
Other comprehensive income     $ 0 0   $ 0 0    
Provision for Income taxes [Abstract]                  
Unrecognized tax benefits     0 0   $ 0 0    
Subsequent Event [Member]                  
Subsequent Event [Line Items]                  
Additional lease term extension period 1 year                
Monthly base rent $ 10,757                
Notice period to cancel lease agreements 3 months                
Minimum [Member]                  
Property, Plant and Equipment [Line Items]                  
Estimated useful life of property, plant and equipment           5 years      
Maximum [Member]                  
Property, Plant and Equipment [Line Items]                  
Estimated useful life of property, plant and equipment           10 years      
Recurring [Member] | Institutional Money Market [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Cash equivalents     1,894,904     $ 1,894,904   715,784  
Recurring [Member] | Municipal Bonds [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Investments     6,917,696     6,917,696   6,617,042  
Recurring [Member] | Corporate Bonds [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Investments     32,413,045     32,413,045   11,480,000  
Recurring [Member] | Certificates of Deposit [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Investments     7,187,928     7,187,928   13,847,041  
Recurring [Member] | Level 1 [Member] | Institutional Money Market [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Cash equivalents     1,894,904     1,894,904   715,784  
Recurring [Member] | Level 1 [Member] | Municipal Bonds [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Investments     0     0   0  
Recurring [Member] | Level 1 [Member] | Corporate Bonds [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Investments     0     0   0  
Recurring [Member] | Level 1 [Member] | Certificates of Deposit [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Investments     7,187,928     7,187,928   13,847,041  
Recurring [Member] | Level 2 [Member] | Institutional Money Market [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Cash equivalents     0     0   0  
Recurring [Member] | Level 2 [Member] | Municipal Bonds [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Investments     6,917,696     6,917,696   6,617,042  
Recurring [Member] | Level 2 [Member] | Corporate Bonds [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Investments     32,413,045     32,413,045   11,480,000  
Recurring [Member] | Level 2 [Member] | Certificates of Deposit [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Investments     0     0   0  
Recurring [Member] | Level 3 [Member] | Institutional Money Market [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Cash equivalents     0     0   0  
Recurring [Member] | Level 3 [Member] | Municipal Bonds [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Investments     0     0   0  
Recurring [Member] | Level 3 [Member] | Corporate Bonds [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Investments     0     0   0  
Recurring [Member] | Level 3 [Member] | Certificates of Deposit [Member]                  
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                  
Investments     0     0   0  
Endo [Member]                  
Concentration Risk [Line Items]                  
Royalty revenue     6,900,000 6,300,000   19,600,000 16,600,000    
Accounts receivable     3,800,000     3,800,000   2,500,000  
Royalty / Mark-Up on Cost of Goods Sold [Abstract]                  
Deferred revenue on licensing agreements                 $ 8,250,000
Proceeds from licensing agreement   $ 8,250,000 750,000 0   750,000 0    
Deferred Revenue [Abstract]                  
Deferred revenue recognized     274,000 0   546,000 0    
Deferred revenue     7,700,000     7,700,000      
Municipal Bonds [Member]                  
Schedule of Held-to-maturity Securities [Line Items]                  
Held-to-maturity securities, current     6,917,696     6,917,696   6,461,216  
Held-to-maturity securities, noncurrent     0     0   155,826  
Corporate Bonds [Member]                  
Schedule of Held-to-maturity Securities [Line Items]                  
Held-to-maturity securities, current     31,218,996     31,218,996   9,882,285  
Held-to-maturity securities, noncurrent     1,194,049     1,194,049   1,597,715  
Certificates of Deposit [Member]                  
Schedule of Held-to-maturity Securities [Line Items]                  
Held-to-maturity securities, current     6,938,878     6,938,878   12,004,041  
Held-to-maturity securities, noncurrent     249,050     249,050   $ 1,843,000  
General and Administrative [Member]                  
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]                  
Stock-based compensation expense     $ 33,000 $ 33,000   $ 100,000 $ 72,000    
Stock Options [Member]                  
Stock Option Activity [Roll Forward]                  
Outstanding, beginning of period (in shares) | shares           562,000      
Grants (in shares) | shares           0 0    
Exercised (in shares) | shares           (255,000)      
Forfeitures or expirations (in shares) | shares           0      
Outstanding, end of period (in shares) | shares     307,000     307,000   562,000  
Exercisable, end of period (in shares) | shares     260,750     260,750      
Weighted-Average Exercise Price [Roll Forward]                  
Outstanding, beginning of period (in dollars per share) | $ / shares           $ 11.91      
Grants (in dollars per share) | $ / shares           0      
Exercised (in dollars per share) | $ / shares           2.08      
Forfeitures or expirations (in dollars per share) | $ / shares           0      
Outstanding, end of period (in dollars per share) | $ / shares     $ 20.08     20.08   $ 11.91  
Exercisable, end of period (in dollars per share) | $ / shares     $ 17.89     $ 17.89      
Weighted Average Remaining Contractual Term [Roll Forward]                  
Weighted average remaining contractual term, outstanding           3 years 3 months 29 days   2 years 6 months 4 days  
Weighted average remaining contractual term, exercisable           2 years 9 months 29 days      
Aggregate Intrinsic Value [Roll Forward]                  
Aggregate intrinsic value, outstanding           $ 17,456,220      
Aggregate intrinsic value, grants           0      
Aggregate intrinsic value, exercised           0      
Aggregate intrinsic value, forfeitures or expirations           0      
Aggregate intrinsic value, outstanding     $ 7,857,070     7,857,070   $ 17,456,220  
Aggregate intrinsic value, exercisable     7,243,095     7,243,095      
Additional Disclosures [Abstract]                  
Proceeds from stock option exercises           500,000 $ 2,800,000    
Unrecognized compensation cost related to non-vested stock options outstanding     $ 301,000     $ 301,000      
Recognized compensation period           2 years 4 months 24 days      
XML 30 R20.htm IDEA: XBRL DOCUMENT v3.5.0.2
NET INCOME PER SHARE (Details) - Stock Options [Member] - $ / shares
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]        
Antidilutive securities excluded from earnings per share calculation (in shares) 20,000 20,000 20,000 20,000
Exercise price (in dollars per share) $ 29.21   $ 29.21  
XML 31 R21.htm IDEA: XBRL DOCUMENT v3.5.0.2
ACCOUNTS PAYABLE AND ACCRUED EXPENSES (Details) - USD ($)
Sep. 30, 2016
Dec. 31, 2015
Accounts payable and accrued expenses [Abstract]    
Trade accounts payable and accrued expenses $ 728,425 $ 372,367
Accrued legal and other professional fees 66,775 74,138
Accrued payroll and related costs 196,667 164,504
Total $ 991,867 $ 611,009
XML 32 R22.htm IDEA: XBRL DOCUMENT v3.5.0.2
PATENT COSTS (Details) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Dec. 31, 2015
Net Patent Costs [Abstract]          
Net patent costs $ 268,928   $ 268,928   $ 275,206
Patents [Member]          
Finite-Lived Intangible Assets [Line Items]          
Increase in capitalized patent costs     23,300    
Net Patent Costs [Abstract]          
Patents 720,600   720,600   697,260
Accumulated amortization (451,672)   (451,672)   (422,054)
Net patent costs 268,928   268,928   $ 275,206
Amortization expense for patents 10,300 $ 11,000 29,600 $ 34,000  
Estimated amortization expense [Abstract]          
October 1, 2016 to December 31, 2016 10,600   10,600    
2017 38,700   38,700    
2018 38,700   38,700    
2019 38,700   38,700    
2020 27,400   27,400    
Thereafter $ 114,800   $ 114,800    
Patents [Member] | Minimum [Member]          
Finite-Lived Intangible Assets [Line Items]          
Estimated useful lives     1 year    
Patents [Member] | Maximum [Member]          
Finite-Lived Intangible Assets [Line Items]          
Estimated useful lives     12 years    
XML 33 R23.htm IDEA: XBRL DOCUMENT v3.5.0.2
PROVISION FOR INCOME TAXES (Details) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Dec. 31, 2015
PROVISION FOR INCOME TAXES [Abstract]          
Provision for income taxes $ 1,759,220 $ 1,479,200 $ 4,497,359 $ 3,654,772  
Deferred tax assets 3,400,000   3,400,000   $ 600,000
Uncertain tax positions 0 $ 0 0 $ 0  
Interest and penalties $ 0   $ 0    
XML 34 R24.htm IDEA: XBRL DOCUMENT v3.5.0.2
SUBSEQUENT EVENTS (Details) - Subsequent Event [Member]
Nov. 01, 2016
USD ($)
Subsequent Event [Line Items]  
Additional lease term extension period 1 year
Monthly base rent $ 10,757
Notice period to cancel lease agreements 3 months
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