-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 WGCFdtlKSR4zb202yRlkmd0PS04/HxSR8ZbF4zJPa2n+WJKqCTB91ufQpCwIqvfd
 jYSW47cjsSxFEHgYfOSz9g==

<SEC-DOCUMENT>0000950120-08-000234.txt : 20080523
<SEC-HEADER>0000950120-08-000234.hdr.sgml : 20080523
<ACCEPTANCE-DATETIME>20080523115251
ACCESSION NUMBER:		0000950120-08-000234
CONFORMED SUBMISSION TYPE:	4/A
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080114
FILED AS OF DATE:		20080523
DATE AS OF CHANGE:		20080523

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BIOSPECIFICS TECHNOLOGIES CORP
		CENTRAL INDEX KEY:			0000875622
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				113054851
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		35 WILBUR ST
		CITY:			LYNBROOK
		STATE:			NY
		ZIP:			11563
		BUSINESS PHONE:		5165937000

	MAIL ADDRESS:	
		STREET 1:		35 WILBUR STREET
		CITY:			LYNBROOK
		STATE:			NY
		ZIP:			11563

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Wegman Toby
		CENTRAL INDEX KEY:			0001405128

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-19879
		FILM NUMBER:		08856995

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		(561) 988-0270

	MAIL ADDRESS:	
		STREET 1:		4092 BOCAIRE BLVD.
		CITY:			BOCA RATON
		STATE:			FL
		ZIP:			33487
</SEC-HEADER>
<DOCUMENT>
<TYPE>4/A
<SEQUENCE>1
<FILENAME>tobyweg-bioform4a_0523ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4/A</documentType>

    <periodOfReport>2008-01-14</periodOfReport>

    <dateOfOriginalSubmission>2008-02-05</dateOfOriginalSubmission>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000875622</issuerCik>
        <issuerName>BIOSPECIFICS TECHNOLOGIES CORP</issuerName>
        <issuerTradingSymbol>BSTC.OB</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001405128</rptOwnerCik>
            <rptOwnerName>Wegman Toby</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>4092 BOCAIRE BLVD.</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>BOCA RATON</rptOwnerCity>
            <rptOwnerState>FL</rptOwnerState>
            <rptOwnerZipCode>33487</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, $0.001 par value</value>
            </securityTitle>
            <transactionDate>
                <value>2008-01-14</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>243149</value>
                    <footnoteId id="F1"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1805293</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>Held by the Estate of Edwin H. Wegman</value>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">This amendment is being filed to correct the number of shares of the Issuer's common stock that were distributed by The S.J.
 Wegman Company, a New York limited partnership (&quot;SJW&quot;), to certain of its limited partners on January 14, 2008.  On January
 14, 2008, SJW distributed 243,149 shares to certain of its limited partners.  The initial Form 4 filed on February 5, 2008
 incorrectly reported that 618,331 shares were distributed.</footnote>
        <footnote id="F2">The Reporting Person is an executor and beneficiary of the Estate of Edwin H. Wegman (the &quot;Estate&quot;) and is therefore deemed
 to beneficially own shares of the Issuer's common stock that are held by SJW, for the benefit of the Estate as well as
 shares that are held directly by the Estate.  As of January 14, 2008, the Reporting Person beneficially owned indirectly
 1,805,293 shares held by the Estate.  As of the date of this filing and as reported in the Issuer's Form 10KSB filed on May
 2, 2008, the Reporting Person beneficially owns (i) indirectly 1,400,179 shares held by the Estate and (ii) directly options
 to purchase 15,000 shares.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Toby Wegman</signatureName>
        <signatureDate>2008-05-23</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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