<SEC-DOCUMENT>0001209191-22-006767-index.html : 20220203
<SEC-HEADER>0001209191-22-006767.hdr.sgml : 20220203
<ACCEPTANCE-DATETIME>20220203161246
ACCESSION NUMBER:		0001209191-22-006767
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20220201
FILED AS OF DATE:		20220203
DATE AS OF CHANGE:		20220203

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Arbuckle Stuart A
		CENTRAL INDEX KEY:			0001557290

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-19319
		FILM NUMBER:		22588408

	MAIL ADDRESS:	
		STREET 1:		VERTEX PHARMACEUTICALS INCORPORATED
		STREET 2:		130 WAVERLY ST.
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			VERTEX PHARMACEUTICALS INC / MA
		CENTRAL INDEX KEY:			0000875320
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				043039129
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		50 NORTHERN AVENUE
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02210
		BUSINESS PHONE:		6173416393

	MAIL ADDRESS:	
		STREET 1:		50 NORTHERN AVENUE
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02210
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
Document 1 - file: doc4.html

Document 1 - RAW XML: doc4.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>attachment1.htm
<DESCRIPTION>EX-24 DOCUMENT
<TEXT>
Document 2 - file: attachment1.htm

</DOCUMENT>
</SEC-DOCUMENT>