<SEC-DOCUMENT>0001193125-24-093208-index.html : 20240411
<SEC-HEADER>0001193125-24-093208.hdr.sgml : 20240411
<ACCEPTANCE-DATETIME>20240411160856
ACCESSION NUMBER:		0001193125-24-093208
CONFORMED SUBMISSION TYPE:	SC TO-C
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20240411
DATE AS OF CHANGE:		20240411
GROUP MEMBERS:		ADAMS MERGER SUB, INC.

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ALPINE IMMUNE SCIENCES, INC.
		CENTRAL INDEX KEY:			0001626199
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				208969493
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC TO-C
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-88896
		FILM NUMBER:		24838588

	BUSINESS ADDRESS:	
		STREET 1:		188 EAST BLAINE ST., SUITE 200
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98102
		BUSINESS PHONE:		206-788-4545

	MAIL ADDRESS:	
		STREET 1:		188 EAST BLAINE ST., SUITE 200
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98102

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Nivalis Therapeutics, Inc.
		DATE OF NAME CHANGE:	20150211

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	N30 Pharmaceuticals, Inc.
		DATE OF NAME CHANGE:	20141121

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			VERTEX PHARMACEUTICALS INC / MA
		CENTRAL INDEX KEY:			0000875320
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				043039129
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC TO-C

	BUSINESS ADDRESS:	
		STREET 1:		50 NORTHERN AVENUE
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02210
		BUSINESS PHONE:		6173416393

	MAIL ADDRESS:	
		STREET 1:		50 NORTHERN AVENUE
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02210
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC TO-C
<SEQUENCE>1
<FILENAME>d712820dsctoc.htm
<DESCRIPTION>SC TO-C
<TEXT>
Document 1 - file: d712820dsctoc.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>d712820dex991.htm
<DESCRIPTION>EX-99.1
<TEXT>
Document 2 - file: d712820dex991.htm

</DOCUMENT>
</SEC-DOCUMENT>