-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0001104659-09-018441.txt : 20090318
<SEC-HEADER>0001104659-09-018441.hdr.sgml : 20090318
<ACCEPTANCE-DATETIME>20090318095635
ACCESSION NUMBER:		0001104659-09-018441
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20090318
DATE AS OF CHANGE:		20090318
EFFECTIVENESS DATE:		20090318

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			VERTEX PHARMACEUTICALS INC / MA
		CENTRAL INDEX KEY:			0000875320
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				043039129
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-128109
		FILM NUMBER:		09689885

	BUSINESS ADDRESS:	
		STREET 1:		130 WAVERLY STREET
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139-4242
		BUSINESS PHONE:		6165776000
</SEC-HEADER>
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    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
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        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
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                <signatureName>/S/ Kenneth S. Boger</signatureName>
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