Accrued Expenses and Other Current Liabilities (Tables)

12 Months Ended

Dec. 31, 2011

Accrued Expenses and Other Current Liabilities

Accrued expenses and other current liabilities

	At December 31,
	2011		2010
	(in thousands)
Research and development contract costs	$	66,426	$	55,506
Payroll and benefits		57,453		50,041
Product revenue allowances		58,201		—
Royalty payable		28,603		2,869
State income taxes		3,691		—
Unrecognized tax benefits		4,360		2,374
Professional fees		12,785		8,629
Other		20,780		14,995
Total	$	252,299	$	134,414