Stock-based Compensation Expense (Tables)

6 Months Ended

Jun. 30, 2011

Stock-based Compensation Expense

Stock-based compensation expense by type of award

		Three Months Ended June 30,					Six Months Ended June 30,
		2011			2010		2011			2010
		(in thousands)
Stock-based compensation expense by type of award:
	Stock options	$	23,903		$	17,735	$	43,527		$	31,203
	Restricted stock and restricted stock units		6,835			5,743		13,665			10,490
	ESPP share issuances		1,523			971		3,102			2,089
	Less stock-based compensation expense capitalized to inventory		(382	)		—		(536	)		—
Total stock-based compensation expense included in net loss		$	31,879		$	24,449	$	59,758		$	43,782
Stock-based compensation expense by line item:
	Research and development expenses	$	20,453		$	17,735	$	39,002		$	32,055
	Sales, general and administrative expenses		11,426			6,714		20,756			11,727
Total stock-based compensation expense included in net loss		$	31,879		$	24,449	$	59,758		$	43,782

Unrecognized stock-based compensation expense, net of forfeitures

		As of June 30, 2011
		Unrecognized Expense, Net of Estimated Forfeitures		Weighted-average Recognition Period
		(in thousands)		(in years)
Type of award:
	Stock options	$	131,167		2.65
	Restricted stock and restricted stock units		43,527		2.36
	ESPP share issuances		2,522		0.56

Stock options outstanding and exercisable

	Options Outstanding						Options Exercisable
Range of Exercise Prices	Number Outstanding		Weighted-average Remaining Contractual Life		Weighted-average Exercise Price		Number Exercisable		Weighted-average Exercise Price
	(in thousands)		(in years)		(per share)		(in thousands)		(per share)
$  8.68-$20.00		3,050		3.61	$	15.54		2,839	$	15.30
$20.01-$30.00		1,862		5.11		27.81		1,734		27.85
$30.01-$40.00		15,063		7.74		35.69		7,110		35.04
$40.01-$50.00		277		8.56		45.28		54		43.31
$50.01-$57.27		337		9.88		54.52		164		53.81