Exhibit 23.3

                       CONSENT OF INDEPENDENT ACCOUNTANTS

We hereby consent to the incorporation by reference in this Amendment No. 1
to the Registration Statement on Form S-4 (File No. 333-61480) of Vertex
Pharmaceuticals Incorporated of our report dated February 22, 2001 relating
to the financial statements, which appears in Vertex Pharmaceuticals
Incorporated's Annual Report on Form 10-K for the year ended December 31,
2000. We also consent to the reference to us under the heading "Experts" in
such Registration Statement.

/s/ PricewaterhouseCoopers LLP

Boston, Massachusetts
June 7, 2001