Exhibit 23.3

                       CONSENT OF INDEPENDENT ACCOUNTANTS

We hereby consent to the incorporation by reference in this Registration
Statement on Form S-4 of Vertex Pharmaceuticals Incorporated of our report
dated February 22, 2001 relating to the financial statements, which appears
in Vertex Pharmaceuticals Incorporated's Annual Report on Form 10-K for the
year ended December 31, 2000. We also consent to the reference to us under
the heading "Experts" in such Registration Statement.

/s/ PricewaterhouseCoopers LLP

Boston, Massachusetts
May 22, 2001