Stock-based Compensation Expense and Share Repurchase Programs - Stock-based Compensation Expense (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	$ 130.9	$ 135.6	$ 372.6	$ 379.8
Stock-based compensation expense related to inventories	(0.8)	0.3	(1.8)	0.4
Total stock-based compensation expense included in “Total costs and expenses”	130.9	135.6	372.6	379.8
Income tax effect	(37.1)	(38.8)	(109.0)	(101.3)
Total stock-based compensation expense, net of tax	93.8	96.8	263.6	278.5
Cost of sales
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	1.7	2.4	5.4	7.0
Research and development expenses
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	81.1	80.0	231.9	229.9
Selling, general and administrative expenses
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	48.1	53.2	135.3	142.9
Restricted stock units (including PSUs)
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	129.1	130.3	358.6	351.5
Stock options
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	0.2	3.1	4.0	14.9
ESPP share issuances
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	$ 2.4	$ 1.9	$ 11.8	$ 13.0