Revenue Recognition (Tables)

9 Months Ended

Sep. 30, 2023

Revenue from Contract with Customer [Abstract]

Schedule of Disaggregation of Revenue

“Product revenues, net” consisted of the following:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2023		2022		2023		2022
	(in millions)
TRIKAFTA/KAFTRIO	$	2,274.3	$	2,010.5	$	6,611.4	$	5,665.3
KALYDECO	112.8		139.4		363.1		417.1
ORKAMBI	63.0		146.2		281.8		399.9
SYMDEKO/SYMKEVI	33.4		38.2		95.2		145.7
Total product revenues, net	$	2,483.5	$	2,334.3	$	7,351.5	$	6,628.0

“Product revenues, net” by geographic region, based on the location of the customer, consisted of the following:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2023		2022		2023		2022
	(in millions)
United States	$	1,554.2	$	1,455.6	$	4,465.8	$	4,238.9
Outside of the United States
Europe	766.5		730.5		2,373.7		2,018.3
Other	162.8		148.2		512.0		370.8
Total product revenues outside of the United States	929.3		878.7		2,885.7		2,389.1
Total product revenues, net	$	2,483.5	$	2,334.3	$	7,351.5	$	6,628.0