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Hedging - Cash Flow Hedging Instruments (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Derivative Instruments, Gain (Loss) [Line Items]        
Product revenues, net $ 2,493.2 $ 2,196.2 $ 4,868.0 $ 4,293.7
Other income (expense), net 1.6 (78.1) 2.9 (150.9)
Foreign Currency Forward Contract | Reclassification out of Accumulated Other Comprehensive Income | Foreign currency forward contracts | Designated as hedging instruments        
Derivative Instruments, Gain (Loss) [Line Items]        
Product revenues, net 8.2 45.0 30.2 65.1
Foreign Currency Forward Contract | Reclassification out of Accumulated Other Comprehensive Income | Foreign currency forward contracts | Not designated as hedging instruments        
Derivative Instruments, Gain (Loss) [Line Items]        
Other income (expense), net $ 0.6 $ (8.4) $ 4.2 $ (16.8)