Condensed Consolidated Statements of Income - USD ($) shares in Millions, $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Revenues:
Product revenues, net	$ 2,493.2	$ 2,196.2	$ 4,868.0	$ 4,293.7
Costs and expenses:
Cost of sales	308.6	261.8	575.5	507.6
Research and development expenses	785.7	600.1	1,528.3	1,201.2
Acquired in-process research and development expenses	110.5	61.9	457.6	63.9
Selling, general and administrative expenses	262.6	215.3	503.7	430.5
Change in fair value of contingent consideration	(0.6)	(49.2)	(2.5)	(56.7)
Total costs and expenses	1,466.8	1,089.9	3,062.6	2,146.5
Income from operations	1,026.4	1,106.3	1,805.4	2,147.2
Interest income	144.7	10.8	267.3	12.4
Interest expense	(11.2)	(14.6)	(22.6)	(29.5)
Other income (expense), net	1.6	(78.1)	2.9	(150.9)
Income before provision for income taxes	1,161.5	1,024.4	2,053.0	1,979.2
Provision for income taxes	245.8	213.9	437.5	406.6
Net income	$ 915.7	$ 810.5	$ 1,615.5	$ 1,572.6
Net income per common share:
Basic (in dollars per share)	$ 3.55	$ 3.17	$ 6.27	$ 6.15
Diluted (in dollars per share)	$ 3.52	$ 3.13	$ 6.21	$ 6.09
Shares used in per share calculations:
Basic (in shares)	257.7	255.9	257.6	255.5
Diluted (in shares)	260.4	258.7	260.3	258.3