Condensed Consolidated Statements of Cash Flows - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Cash flows from operating activities:
Net income	$ 699.8	$ 762.1
Adjustments to reconcile net income to net cash provided by operating activities:
Stock-based compensation expense	122.4	130.3
Depreciation expense	38.8	35.9
Deferred income taxes	(113.4)	(12.3)
(Gains) losses on equity securities	(6.4)	75.6
Decrease in fair value of contingent consideration	(1.9)	(7.5)
Other non-cash items, net	21.7	4.9
Changes in operating assets and liabilities:
Accounts receivable, net	(90.5)	(165.2)
Inventories	(82.6)	2.0
Prepaid expenses and other assets	46.2	67.6
Accounts payable	35.7	(14.5)
Accrued expenses	140.7	61.6
Other liabilities	89.4	15.7
Net cash provided by operating activities	899.9	956.2
Cash flows from investing activities:
Purchases of available-for-sale debt securities	(1,816.6)	(117.1)
Maturities of available-for-sale debt securities	50.0	129.7
Purchases of property and equipment	(42.1)	(63.6)
Investment in equity securities	(24.9)	0.0
Net cash used in investing activities	(1,833.6)	(51.0)
Cash flows from financing activities:
Issuances of common stock under benefit plans	14.2	33.7
Repurchases of common stock	(132.8)	0.0
Payments in connection with common stock withheld for employee tax obligations	(166.6)	(117.5)
Payments on finance leases	(10.6)	(12.9)
Other financing activities	1.1	1.3
Net cash used in financing activities	(294.7)	(95.4)
Effect of changes in exchange rates on cash	12.0	(5.9)
Net (decrease) increase in cash, cash equivalents and restricted cash	(1,216.4)	803.9
Cash, cash equivalents and restricted cash—beginning of period	10,512.0	6,800.1
Cash, cash equivalents and restricted cash—end of period	9,295.6	7,604.0
Supplemental disclosure of cash flow information:
Cash paid for income taxes	120.3	85.0
Cash paid for interest	$ 11.1	$ 13.7