Revenue Recognition (Tables)

3 Months Ended

Mar. 31, 2023

Revenue from Contract with Customer [Abstract]

Schedule of Disaggregation of Revenue

“Product revenues, net” consisted of the following:

	Three Months Ended March 31,
	2023		2022
	(in millions)
TRIKAFTA/KAFTRIO	$	2,096.7	$	1,761.6
KALYDECO	125.0		139.0
ORKAMBI	122.5		132.1
SYMDEKO/SYMKEVI	30.6		64.8
Total product revenues, net	$	2,374.8	$	2,097.5

“Product revenues, net” by geographic region, based on the location of the customer, consisted of the following:

	Three Months Ended March 31,
	2023		2022
	(in millions)
United States	$	1,403.8	$	1,368.2
Outside of the United States
Europe	807.2		632.3
Other	163.8		97.0
Total product revenues outside of the United States	971.0		729.3
Total product revenues, net	$	2,374.8	$	2,097.5