Condensed Consolidated Statements of Income - USD ($) shares in Millions, $ in Millions	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Revenues:
Product revenues, net	$ 2,374.8	$ 2,097.5
Costs and expenses:
Cost of sales	266.9	245.8
Research and development expenses	742.6	601.1
Acquired in-process research and development expenses	347.1	2.0
Selling, general and administrative expenses	241.1	215.2
Change in fair value of contingent consideration	(1.9)	(7.5)
Total costs and expenses	1,595.8	1,056.6
Income from operations	779.0	1,040.9
Interest income	122.6	1.6
Interest expense	(11.4)	(14.9)
Other income (expense), net	1.3	(72.8)
Income before provision for income taxes	891.5	954.8
Provision for income taxes	191.7	192.7
Net income	$ 699.8	$ 762.1
Net income per common share:
Basic (in dollars per share)	$ 2.72	$ 2.99
Diluted (in dollars per share)	$ 2.69	$ 2.96
Shares used in per share calculations:
Basic (in shares)	257.4	255.1
Diluted (in shares)	260.3	257.9