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Acquired In-Process Research and Development and Other Arrangements (Tables)
6 Months Ended
Jun. 30, 2022
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Schedule of Collaborative Arrangement Costs During the three and six months ended June 30, 2022 and 2021, we recognized the following amounts in total, not including amounts recorded to “Acquired in-process research and development expenses,” related to these agreements:
Three Months Ended June 30,Six Months Ended June 30,
2022202120222021
(in millions)
Total expenses incurred under the Original CTX001 JDCA and A&R JDCA$85.0 $55.0 $161.6 $95.0 
Vertex’s share recognized in “Total costs and expenses” in our condensed consolidated statements of operations
50.9 27.5 96.9 47.5