Condensed Consolidated Statements of Operations - USD ($) shares in Millions, $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenues:
Product revenues, net	$ 2,196.2	$ 1,793.4	$ 4,293.7	$ 3,517.7
Costs and expenses:
Cost of sales	261.8	228.0	507.6	420.3
Research and development expenses	600.1	448.7	1,201.2	903.0
Acquired in-process research and development expenses	61.9	958.4	63.9	960.1
Selling, general and administrative expenses	215.3	194.6	430.5	386.7
Change in fair value of contingent consideration	(49.2)	1.6	(56.7)	(2.3)
Total costs and expenses	1,089.9	1,831.3	2,146.5	2,667.8
Income (loss) from operations	1,106.3	(37.9)	2,147.2	849.9
Interest income	10.8	1.1	12.4	2.6
Interest expense	(14.6)	(15.5)	(29.5)	(31.2)
Other (expense) income, net	(78.1)	8.1	(150.9)	(44.6)
Income (loss) before provision for (benefit from) income taxes	1,024.4	(44.2)	1,979.2	776.7
Provision for (benefit from) income taxes	213.9	(111.2)	406.6	56.6
Net income	$ 810.5	$ 67.0	$ 1,572.6	$ 720.1
Net income per common share:
Basic (in dollars per share)	$ 3.17	$ 0.26	$ 6.15	$ 2.78
Diluted (in dollars per share)	$ 3.13	$ 0.26	$ 6.09	$ 2.75
Shares used in per share calculations:
Basic (in shares)	255.9	259.0	255.5	259.2
Diluted (in shares)	258.7	261.0	258.3	261.5
Product revenues, net
Revenues:
Product revenues, net	$ 2,196.2	$ 1,793.4	$ 4,293.7	$ 3,516.7
Other revenues
Revenues:
Product revenues, net	$ 0.0	$ 0.0	$ 0.0	$ 1.0