Condensed Consolidated Statements of Cash Flows - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Cash flows from operating activities:
Net income	$ 762.1	$ 653.1
Adjustments to reconcile net income to net cash provided by operating activities:
Stock-based compensation expense	130.3	115.2
Depreciation expense	35.9	28.8
Decrease in fair value of contingent consideration	(7.5)	(3.9)
Deferred income taxes	(12.3)	57.0
Losses on equity securities	75.6	52.3
Other non-cash items, net	4.9	2.3
Changes in operating assets and liabilities:
Accounts receivable, net	(165.2)	(98.4)
Inventories	2.0	(22.8)
Prepaid expenses and other assets	67.6	(13.3)
Accounts payable	(14.5)	(10.6)
Accrued expenses	61.6	153.0
Other liabilities	15.7	8.3
Net cash provided by operating activities	956.2	921.0
Cash flows from investing activities:
Purchases of available-for-sale debt securities	(117.1)	(121.5)
Maturities of available-for-sale debt securities	129.7	118.1
Purchases of property and equipment	(63.6)	(70.9)
Net cash used in investing activities	(51.0)	(74.3)
Cash flows from financing activities:
Issuances of common stock under benefit plans	33.7	15.6
Repurchases of common stock	0.0	(424.9)
Payments in connection with common stock withheld for employee tax obligations	(117.5)	(102.1)
Payments on finance leases	(12.9)	(12.2)
Proceeds from finance leases	0.0	3.6
Other financing activities	1.3	1.3
Net cash used in financing activities	(95.4)	(518.7)
Effect of changes in exchange rates on cash	(5.9)	(4.0)
Net increase in cash, cash equivalents and restricted cash	803.9	324.0
Cash, cash equivalents and restricted cash—beginning of period	6,800.1	5,988.9
Cash, cash equivalents and restricted cash—end of period	7,604.0	6,312.9
Supplemental disclosure of cash flow information:
Cash paid for interest	13.7	14.5
Cash paid for income taxes	$ 85.0	$ 10.7