Hedging - Cash Flow Hedging Instruments (Details) - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Derivative Instruments, Gain (Loss) [Line Items]
Product revenues, net	$ 2,097.5	$ 1,724.3
Other expense, net	(72.8)	(52.7)
Foreign Currency Forward Contract | Reclassification out of Accumulated Other Comprehensive Income | Foreign Currency Forward Contracts | Not designated as hedging instruments
Derivative Instruments, Gain (Loss) [Line Items]
Other expense, net	(8.4)	(8.0)
Product revenues, net
Derivative Instruments, Gain (Loss) [Line Items]
Product revenues, net	2,097.5	1,723.3
Product revenues, net | Foreign Currency Forward Contract | Reclassification out of Accumulated Other Comprehensive Income | Foreign Currency Forward Contracts | Designated as hedging instruments
Derivative Instruments, Gain (Loss) [Line Items]
Product revenues, net	$ 20.1	$ (16.5)