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Stock-based Compensation Expense and Share Repurchase Programs (Tables)
3 Months Ended
Mar. 31, 2022
Share-based Payment Arrangement [Abstract]  
Schedule of Stock-based Compensation Expense by Line Item
During the three months ended March 31, 2022 and 2021, we recognized the following stock-based compensation expense:
Three Months Ended March 31,
20222021
(in millions)
Stock-based compensation expense by type of award:
Restricted stock units (including PSUs)$118.2 $100.8 
Stock options5.5 10.6 
ESPP share issuances6.8 5.6 
Stock-based compensation expense related to inventories
(0.2)(1.8)
Total stock-based compensation expense included in costs and expenses
$130.3 $115.2 
Stock-based compensation expense by line item:
Cost of sales$2.2 $1.4 
Research and development expenses80.4 72.8 
Selling, general and administrative expenses47.7 41.0 
Total stock-based compensation expense included in costs and expenses
130.3 115.2 
Income tax effect(36.0)(31.3)
Total stock-based compensation expense, net of tax
$94.3 $83.9