Collaborative and Other Arrangements (Tables)

3 Months Ended

Mar. 31, 2022

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Schedule of Collaborative Arrangement Costs

During the three months ended March 31, 2022 and 2021, we recognized the following amounts in total related to these agreements:

	Three Months Ended March 31,
	2022		2021
	(in millions)
Total research and development expenses incurred under the Original CTX001 JDCA and A&R JDCA	$	76.6	$	40.0
Vertex’s share recognized in “Total costs and expenses” in our condensed consolidated statements of operations	46.0		20.0