Stock-based Compensation Expense (Details)	12 Months Ended
	Dec. 31, 2021 USD ($) installment $ / shares shares	Dec. 31, 2020 USD ($) $ / shares shares	Dec. 31, 2019 USD ($) $ / shares shares
Stock-based compensation expense:
Stock-based compensation expense related to inventories	$ 441,400,000	$ 429,500,000	$ 360,500,000
Income tax effect	(82,900,000)	(147,000,000.0)	(124,200,000)
Total stock-based compensation included in costs and expenses, net of tax	358,500,000	282,500,000	236,300,000
Stock-based compensation expense related to inventories	(4,100,000)	$ (3,600,000)	$ (1,700,000)
Share-based Payment Arrangement, Additional Disclosure [Abstract]
Unrecognized Expense	$ 455,000,000.0
Weighted-average assumptions for options and ESPP subscriptions granted
Stock options granted (in shares) | shares	27,302	22,636	1,520,743
Stock Options
Weighted-average assumptions for options and ESPP subscriptions granted
Expected annual dividends	$ 0.00
Employee stock purchase plan
Weighted-average assumptions for options and ESPP subscriptions granted
Expected stock price volatility (percent)	34.06%	37.70%	33.43%
Risk-free interest rate (percent)	0.05%	0.11%	2.08%
Expected term of options (in years)	8 months 8 days	8 months 15 days	8 months 26 days
Expected annual dividends	$ 0	$ 0	$ 0
Granted (in usd per share) | $ / shares	$ 51.71	$ 65.88	$ 47.79
Restricted stock units (including PSUs)
Stock-based compensation expense:
Stock-based compensation expense	$ 384,300,000	$ 360,400,000	$ 254,300,000
Share-based Payment Arrangement, Additional Disclosure [Abstract]
Unrecognized Expense	$ 423,300,000
Weighted-average Recognition Period	1 year 10 months 28 days
Stock options
Stock-based compensation expense:
Stock-based compensation expense	$ 36,800,000	$ 59,700,000	$ 96,700,000
Share-based Payment Arrangement, Additional Disclosure [Abstract]
Unrecognized Expense	$ 19,100,000
Weighted-average Recognition Period	1 year 1 month 2 days
Weighted-average grant-date fair value, granted ( in usd per share) | $ / shares	$ 65.94	$ 88.37	$ 61.32
Weighted-average assumptions for options and ESPP subscriptions granted
Expected stock price volatility (percent)	35.03%	35.87%	36.99%
Risk-free interest rate (percent)	0.86%	0.43%	2.32%
Expected term of options (in years)	4 years 6 months	4 years 8 months 1 day	4 years 3 months 7 days
Expected annual dividends	$ 0	$ 0	$ 0
ESPP share issuances
Stock-based compensation expense:
Stock-based compensation expense	24,400,000	13,000,000.0	11,200,000
Share-based Payment Arrangement, Additional Disclosure [Abstract]
Unrecognized Expense	$ 12,600,000
Weighted-average Recognition Period	6 months 14 days
Performance-based RSUs
Weighted-average assumptions for options and ESPP subscriptions granted
Potential awards, percent of target shares, minimum	0.00%
Potential awards, percent of target shares, maximum	200.00%
Granted (in usd per share) | $ / shares	$ 212.44
Performance-based RSUs | Tranche one
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting period	3 years
Performance-based RSUs | Tranche two
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting period	3 years
Financial performance shares
Weighted-average assumptions for options and ESPP subscriptions granted
Number of installments | installment	3
Vesting period	3 years
Financial performance shares | Tranche one
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting percentage	33.30%
Financial performance shares | Tranche two
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting percentage	33.30%
Financial performance shares | Tranche three
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting percentage	33.30%
Non-financial performance shares
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting period	3 years
Cost of sales
Stock-based compensation expense:
Stock-based compensation expense related to inventories	$ 6,300,000	5,600,000	5,600,000
Research and development expenses
Stock-based compensation expense:
Stock-based compensation expense related to inventories	268,300,000	262,700,000	224,600,000
Selling, general and administrative expenses
Stock-based compensation expense:
Stock-based compensation expense related to inventories	$ 166,800,000	$ 161,200,000	$ 130,300,000