Hedging - Cash Flow Hedging Instruments (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Derivative Instruments, Gain (Loss) [Line Items]
Revenues	$ 1,984,164	$ 1,538,271	$ 5,501,839	$ 4,577,863
Other income (expense), net	42,368	84,386	(2,234)	139,621
Foreign Currency Forward Contract | Reclassification out of Accumulated Other Comprehensive Income | Foreign Currency Forward Contracts | Not designated as hedging instruments
Derivative Instruments, Gain (Loss) [Line Items]
Other income (expense), net	(400)	25,897	(9,350)	15,724
Product revenues, net
Derivative Instruments, Gain (Loss) [Line Items]
Revenues	1,984,164	1,536,271	5,500,839	4,575,863
Product revenues, net | Foreign Currency Forward Contract | Reclassification out of Accumulated Other Comprehensive Income | Foreign Currency Forward Contracts | Designated as hedging instruments
Derivative Instruments, Gain (Loss) [Line Items]
Revenues	$ (5,224)	$ (7,249)	$ (39,342)	$ 8,039