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Collaborative Arrangements (Tables)
9 Months Ended
Sep. 30, 2021
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Schedule of Collaborative Arrangement on Research and Development During the three and nine months ended September 30, 2021 and 2020, the Company recognized the following amounts in total related to these agreements:
Three Months Ended September 30,Nine Months Ended September 30,
2021202020212020
(in thousands)
Total research and development expenses incurred under the Original CTX001 JDCA and A&R JDCA$58,659 $28,623 $147,448 $66,720 
Vertex’s share recognized in research and development expenses in condensed consolidated statement of operations35,195 14,311 79,590 33,360