Revenue Recognition (Tables)

9 Months Ended

Sep. 30, 2021

Revenue from Contract with Customer [Abstract]

Schedule of Disaggregation of Revenue

Product revenues, net consisted of the following:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2021		2020		2021		2020
	(in thousands)
TRIKAFTA/KAFTRIO	$	1,555,772	$	960,308	$	4,004,600	$	2,773,256
SYMDEKO/SYMKEVI	81,415		156,178		339,969		501,066
ORKAMBI	184,561		225,919		624,224		692,038
KALYDECO	162,416		193,866		532,046		609,503
Total product revenues, net	$	1,984,164	$	1,536,271	$	5,500,839	$	4,575,863

Total net product revenues by geographic region, based on the location of the customer, consisted of the following:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2021		2020		2021		2020
	(in thousands)
United States	$	1,382,892	$	1,222,565	$	3,893,245	$	3,620,467
Outside of the United States
Europe	518,826		251,366		1,382,701		766,438
Other	82,446		62,340		224,893		188,958
Total product revenues outside of the United States	601,272		313,706		1,607,594		955,396
Total product revenues, net	$	1,984,164	$	1,536,271	$	5,500,839	$	4,575,863