Stock-based Compensation Expense (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Stock-based compensation expense:
Stock-based compensation expense	$ 429,461	$ 360,489	$ 325,047
Income tax effect	(146,959)	(124,225)	0
Total stock-based compensation included in costs and expenses, net of tax	282,502	236,264	325,047
Stock-based compensation expense related to inventories	(3,609)	(1,720)	(585)
Stock-based compensation expense related to inventories	$ 429,461	$ 360,489	$ 325,047
Weighted-average assumptions for options and ESPP subscriptions granted
Stock options granted (in shares)	22,636	1,520,743	2,297,328
Stock Options
Weighted-average assumptions for options and ESPP subscriptions granted
Expected annual dividends	$ 0
Employee stock purchase plan
Weighted-average assumptions for options and ESPP subscriptions granted
Expected stock price volatility (percent)	37.70%	33.43%	36.51%
Risk-free interest rate (percent)	0.11%	2.08%	2.36%
Expected term of options (in years)	8 months 15 days	8 months 26 days	9 months
Expected annual dividends	$ 0	$ 0	$ 0
Weighted average fair value ( in usd per share)	$ 65.88	$ 47.79	$ 44.04
Restricted stock units (including PSUs) and restricted stock
Stock-based compensation expense:
Stock-based compensation expense	$ 360,364	$ 254,276	$ 207,845
Share-based Payment Arrangement, Additional Disclosure [Abstract]
Unrecognized Expense	$ 401,100
Weighted-average Recognition Period	1 year 10 months 17 days
Weighted-average assumptions for options and ESPP subscriptions granted
Weighted average fair value ( in usd per share)	$ 0
Stock options
Stock-based compensation expense:
Stock-based compensation expense	$ 59,722	$ 96,737	$ 107,854
Share-based Payment Arrangement, Additional Disclosure [Abstract]
Unrecognized Expense	$ 62,392
Weighted-average Recognition Period	1 year 9 months 7 days
Weighted-average grant-date fair value, granted ( in usd per share)	$ 88.37	$ 61.32	$ 60.83
Weighted-average assumptions for options and ESPP subscriptions granted
Expected stock price volatility (percent)	35.87%	36.99%	40.50%
Risk-free interest rate (percent)	0.43%	2.32%	2.61%
Expected term of options (in years)	4 years 8 months 1 day	4 years 3 months 7 days	4 years 6 months 18 days
Expected annual dividends	$ 0	$ 0	$ 0
ESPP share issuances
Stock-based compensation expense:
Stock-based compensation expense	12,984	11,196	9,933
Share-based Payment Arrangement, Additional Disclosure [Abstract]
Unrecognized Expense	$ 11,333
Weighted-average Recognition Period	7 months 2 days
Performance-based RSUs
Weighted-average assumptions for options and ESPP subscriptions granted
Potential awards, percent of target shares, minimum	0.00%
Potential awards, percent of target shares, maximum	200.00%
Weighted average fair value ( in usd per share)	$ 241.38
Performance-based RSUs | Tranche one
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting period	3 years
Performance-based RSUs | Tranche two
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting period	3 years
Financial performance shares
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting period	3 years
Financial performance shares | Tranche one
Weighted-average assumptions for options and ESPP subscriptions granted
Weighted-average Grant-date Fair Value	33.30%
Financial performance shares | Tranche two
Weighted-average assumptions for options and ESPP subscriptions granted
Weighted-average Grant-date Fair Value	33.30%
Financial performance shares | Tranche three
Weighted-average assumptions for options and ESPP subscriptions granted
Weighted-average Grant-date Fair Value	33.30%
Non-financial performance shares
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting period	3 years
Cost of sales
Stock-based compensation expense:
Stock-based compensation expense	$ 5,579	5,575	4,543
Research and development expenses
Stock-based compensation expense:
Stock-based compensation expense	262,690	224,558	203,112
Sales, general and administrative expenses
Stock-based compensation expense:
Stock-based compensation expense	$ 161,192	$ 130,356	$ 117,392