Stock-based Compensation Expense and Share Repurchase Programs - Stock-based Compensation Expense (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	$ 99,539	$ 85,420	$ 332,434	$ 268,898
Stock-based compensation expense related to inventories	(950)	(536)	(3,076)	(1,236)
Total stock-based compensation expense included in costs and expenses	99,539	85,420	332,434	268,898
Income tax effect	(35,295)	(21,996)	(130,692)	(87,638)
Total stock-based compensation expense, net of tax	64,244	63,424	201,742	181,260
Cost of sales
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	1,250	1,337	3,998	4,178
Research and development expenses
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	60,770	52,504	203,732	167,851
Sales, general and administrative expenses
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	37,519	31,579	124,704	96,869
Restricted stock and restricted stock units (including PSUs)
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	84,043	61,175	279,611	185,651
Stock options
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	13,221	21,737	47,334	76,053
ESPP share issuances
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	$ 3,225	$ 3,044	$ 8,565	$ 8,430