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Revenue Recognition (Tables)
9 Months Ended
Sep. 30, 2020
Revenue from Contract with Customer [Abstract]  
Schedule of Disaggregation of Revenue
Product revenues, net consisted of the following:
Three Months Ended September 30,Nine Months Ended September 30,
2020201920202019
(in thousands)
TRIKAFTA/KAFTRIO$960,308 $— $2,773,256 $— 
SYMDEKO/SYMKEVI156,178 403,714 501,066 1,085,821 
ORKAMBI225,919 296,711 692,038 906,159 
KALYDECO193,866 249,403 609,503 755,481 
Total product revenues, net*
$1,536,271 $949,828 $4,575,863 $2,747,461 
* The preceding table does not include collaborative and royalty revenues.
Total revenues from external customers and collaborators by geographic region consisted of the following:
Three Months Ended September 30,Nine Months Ended September 30,
2020201920202019
(in thousands)
United States
$1,224,565 $710,323 $3,622,467 $2,052,044 
Outside of the United States
Europe
251,366 184,845 766,438 532,809 
Other
62,340 54,660 188,958 164,703 
Total revenues outside of the United States
313,706 239,505 955,396 697,512 
Total revenues
$1,538,271 $949,828 $4,577,863 $2,749,556