Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019
Revenues:
Revenues	$ 1,538,271	$ 949,828	$ 4,577,863	$ 2,749,556
Costs and expenses:
Cost of sales	186,182	131,914	533,199	362,746
Research and development expenses	493,497	555,948	1,362,953	1,274,529
Sales, general and administrative expenses	184,551	159,674	558,613	463,221
Change in fair value of contingent consideration	1,800	2,959	12,600	2,959
Total costs and expenses	866,030	850,495	2,467,365	2,103,455
Income from operations	672,241	99,333	2,110,498	646,101
Interest income	3,100	17,628	19,919	51,319
Interest expense	(13,856)	(14,548)	(41,863)	(44,253)
Other income (expense), net	84,386	(31,747)	139,621	64,802
Income before provision for income taxes	745,871	70,666	2,228,175	717,969
Provision for income taxes	78,437	13,148	120,718	124,393
Net income	$ 667,434	$ 57,518	$ 2,107,457	$ 593,576
Net income per common share:
Basic (in dollars per share)	$ 2.56	$ 0.22	$ 8.10	$ 2.32
Diluted (in dollars per share)	$ 2.53	$ 0.22	$ 7.98	$ 2.28
Shares used in per share calculations:
Basic (in shares)	260,392	256,946	260,313	256,289
Diluted (in shares)	264,079	260,473	264,031	260,182
Product revenues, net
Revenues:
Revenues	$ 1,536,271	$ 949,828	$ 4,575,863	$ 2,747,461
Collaborative and royalty revenues
Revenues:
Revenues	$ 2,000	$ 0	$ 2,000	$ 2,095